KEGG   Escherichia coli BL21(DE3): ECD_00075
Entry
ECD_00075         CDS       T00931                                 
Symbol
leuB
Name
(GenBank) 3-isopropylmalate dehydrogenase, NAD(+)-dependent
  KO
K00052  3-isopropylmalate dehydrogenase [EC:1.1.1.85]
Organism
ebl  Escherichia coli BL21(DE3)
Pathway
ebl00290  Valine, leucine and isoleucine biosynthesis
ebl00660  C5-Branched dibasic acid metabolism
ebl01100  Metabolic pathways
ebl01110  Biosynthesis of secondary metabolites
ebl01210  2-Oxocarboxylic acid metabolism
ebl01230  Biosynthesis of amino acids
Module
ebl_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:ebl00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00660 C5-Branched dibasic acid metabolism
    ECD_00075 (leuB)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    ECD_00075 (leuB)
Enzymes [BR:ebl01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.85  3-isopropylmalate dehydrogenase
     ECD_00075 (leuB)
SSDB
Motif
Pfam: Iso_dh DUF6259
Other DBs
NCBI-ProteinID: ACT41976
Position
complement(83672..84763)
AA seq 363 aa
MSKNYHIAVLPGDGIGPEVMTQALKVLDAVRNRFAMRITTSHYDVGGAAIDNHGQPLPPA
TVEGCEQADAVLFGSVGGPKWEHLPPDQQPERGALLPLRKHFKLFSNLRPAKLYQGLEAF
CPLRADIAANGFDILCVRELTGGIYFGQPKGREGSGQYEKAFDTEVYHRFEIERIARIAF
ESARKRRHKVTSIDKANVLQSSILWREIVNEIATEYPDVELAHMYIDNATMQLIKDPSQF
DVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGLYEPAGGSAPDIAGKNIANPIA
QILSLALLLRYSLDADDAACAIERAINRALEEGIRTGDLARGAAAVSTDEMGDIIARYVA
EGV
NT seq 1092 nt   +upstreamnt  +downstreamnt
atgtcgaagaattaccatattgccgtattgccgggggacggtattggtccggaagtgatg
acccaggcgctgaaagtgctggatgccgtgcgcaaccgctttgcgatgcgcatcaccacc
agccattacgatgtaggcggcgcagccattgataaccacgggcaaccactgccgcctgcg
acggttgaaggttgtgagcaagccgatgccgtgctgtttggctcggtaggcggcccgaag
tgggaacatttaccaccagaccagcaaccagaacgcggcgcgctgctgcctctgcgtaag
cacttcaaattattcagcaacctgcgcccggcaaaactgtatcaggggctggaagcattc
tgtccgctgcgtgcagacattgccgcaaacggcttcgacatcctgtgtgtgcgcgaactg
accggcggcatctatttcggtcagccaaaaggccgcgaaggtagcggacaatatgaaaaa
gcctttgataccgaggtgtatcaccgttttgagatcgaacgtatcgcccgcatcgcgttt
gaatctgctcgcaagcgtcgccacaaagtgacgtcgatcgataaagccaacgtgctgcaa
tcctctattttatggcgggagatcgttaacgagatcgccacggaatacccggatgtcgaa
ctggcgcatatgtacatcgacaacgccaccatgcagctgattaaagatccatcacagttt
gacgttctgctgtgctccaacctgtttggcgacattctgtctgacgagtgcgcaatgatc
actggctcgatggggatgttgccttccgccagcctgaacgagcaaggttttggactgtat
gaaccggcgggcggctcggcaccagatatcgcaggcaaaaacatcgccaacccgattgca
caaatcctttcgctggcactgctgctgcgttacagcctggatgccgatgatgcggcttgc
gccattgaacgcgccattaaccgcgcattagaagaaggcattcgcaccggggatttagcc
cgtggcgctgccgccgttagtaccgatgaaatgggcgatatcattgcccgctatgtagca
gaaggggtgtaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (8)   
   KEGG PATHWAY (6)   
   KEGG MODULE (2)   
Chemical substance (9)   
   KEGG COMPOUND (9)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein domain (2)   
   Pfam (2)   
All databases (29)   

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