KEGG T00931: ECD

Escherichia coli BL21(DE3): ECD_01250

Entry

ECD_01250         CDS       T00931

Symbol

topA

Name

(GenBank) DNA topoisomerase I, omega subunit

K03168

DNA topoisomerase I [EC:5.6.2.1]

Organism

ebl Escherichia coli BL21(DE3)

Brite

KEGG Orthology (KO) [BR:ebl00001]
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:ebl03032]
    ECD_01250 (topA)
   03400 DNA repair and recombination proteins [BR:ebl03400]
    ECD_01250 (topA)
Enzymes [BR:ebl01000]
5. Isomerases
  5.6  Isomerases altering macromolecular conformation
   5.6.2  Enzymes altering nucleic acid conformation
    5.6.2.1  DNA topoisomerase
     ECD_01250 (topA)
DNA replication proteins [BR:ebl03032]
Prokaryotic type
  DNA Topoisomerases
   ECD_01250 (topA)
DNA repair and recombination proteins [BR:ebl03400]
Prokaryotic type
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHIIR (short-homology-independent illegitimate recombination)
     Facilitator
      ECD_01250 (topA)

SSDB

Motif

Pfam:

Topoisom_bac Topo_Zn_Ribbon TOP1_ZnF Toprim zf-C4_Topoisom Zn_ribbon_recom Toprim_4 DUF1722 DUF4795

Other DBs

NCBI-ProteinID:

ACT43139

Position

1317418..1320015

AA seq 865 aa
MGKALVIVESPAKAKTINKYLGSDYVVKSSVGHIRDLPTSGSAAKKSADSTSTKTAKKPK
KDERGALVNRMGVDPWHNWEAHYEVLPGKEKVVSELKQLAEKADHIYLATDLDREGEAIA
WHLREVIGGDDARYSRVVFNEITKNAIRQAFNKPGELNIDRVNAQQARRFMDRVVGYMVS
PLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWEVDASTTTPSGEALALQVTH
QNDKPFRPVNKEQTQAAVSLLEKARYSVLEREDKPTTSKPGAPFITSTLQQAASTRLGFG
VKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVNMVRGYISDNFGKKYLPESPNQYASKEN
SQEAHEAIRPSDVNVMAESLKDMEADAQKLYQLIWRQFVACQMTPAKYDSTTLTVGAGDF
RLKARGRILRFDGWTKVMPALRKGDEDRILPAVNKGDALTLVELTPAQHFTKPPARFSEA
SLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNY
DFTAQMENSLDQVANHEAEWKAVLDHFFSDFTQQLDKAEKDPEEGGMRPNQMVLTSIDCP
TCGRKMGIRTASTGVFLGCSGYALPPKERCKTTINLVPENEVLNVLEGEDAETNALRAKR
RCPKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHL
KMGRFGKYMACTNEECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVF
LAANTFPKSRETRAPLVEELYRFRDRLPEKLRYLADAPQQDPEGNKTMVRFSRKTKQQYV
SSEKDGKATGWSAFYVDGKWVEGKK

NT seq 2598 nt +upstreamnt +downstreamnt
atgggtaaagctcttgtcatcgttgagtccccggcaaaagccaaaacgatcaacaagtat
ctgggtagtgactacgtggtgaaatccagcgtcggtcacatccgcgatttgccgaccagt
ggctcagctgccaaaaagagtgccgactctacctccaccaagacggctaaaaagcctaaa
aaggatgaacgtggcgctctcgtcaaccgtatgggggttgacccgtggcacaattgggag
gcgcactatgaagtgttgcctggtaaagagaaggtcgtctctgaactgaaacaactggct
gaaaaagccgaccacatctatctcgcaaccgaccttgaccgcgaaggggaagccattgca
tggcacctgcgggaagtgattgggggtgatgatgcgcgctatagccgagtggtgtttaac
gaaattactaaaaacgcgatccgccaggcatttaacaaaccgggtgagctgaatattgat
cgtgttaatgcccagcaggcgcgtcgctttatggaccgcgtggtggggtatatggtttcg
ccgctgctatggaaaaagatcgctcgtggtctgtctgccggtcgtgtgcagtcggtggcg
gttcgcctggtggtcgagcgtgagcgtgaaattaaagcgttcgtgccggaagagttctgg
gaagtcgatgccagcacgaccacgccatctggtgaagcgttggcgttacaggtgactcat
cagaacgacaaaccgttccgtccggtcaacaaagaacaaactcaggctgcggtaagtctg
ctggaaaaagcgcgctacagcgtgctggaacgtgaagacaaaccgacaaccagtaaacct
ggcgctccttttattacctctacgctgcaacaagctgccagcacccgtcttggatttggc
gtgaaaaaaaccatgatgatggcgcagcgtttgtatgaagcaggctatatcacttacatg
cgtaccgactccactaacctgagtcaggacgcggtaaatatggttcgcggttatatcagc
gataattttggtaagaaatatctgccggaaagtccgaatcagtacgccagcaaagaaaac
tcacaggaagcgcacgaagcgattcgtccttctgacgtcaatgtgatggcggaatcgctg
aaggatatggaagcagatgcgcagaaactgtaccagttaatctggcgtcagttcgttgcc
tgccagatgaccccagcgaaatatgactccacgacgctgaccgttggtgcgggcgatttc
cgcctgaaagcacgcggtcgtattttgcgttttgatggctggacaaaagtgatgcctgcg
ttgcgtaaaggcgatgaagatcgcatcttaccagcagttaataaaggcgatgctctgacg
ctcgttgaacttacaccagcccagcactttaccaagccgccagcccgtttcagtgaagca
tcgctggttaaagagctggaaaaacgcggtatcggtcgtccgtctacctatgcgtcgatc
atttcgaccattcaggatcgtggctacgtgcgagtagaaaatcgtcgtttctatgcggaa
aaaatgggcgaaatcgtcaccgatcgccttgaagaaaatttccgcgagttaatgaactac
gattttaccgcgcagatggaaaacagcctcgaccaggtggcaaatcacgaagcagagtgg
aaagctgtactggatcacttcttctcggatttcacccagcagttagataaagctgaaaaa
gatccggaagagggtggtatgcgcccgaaccagatggttctgaccagcattgactgcccg
acttgtggtcgcaaaatggggattcgcacagcgagcaccggggtattccttggctgttct
ggctatgcgctgccgccgaaagagcgttgcaaaaccaccattaacctggtgccggaaaac
gaagtgctgaacgtgctggaaggcgaagatgctgaaaccaacgcgctgcgcgcaaaacgt
cgttgcccgaaatgcggcacggcgatggacagctatctcatcgatccgaaacgtaagttg
catgtctgtggtaataacccaacctgcgacggttacgagatcgaagagggcgaattccgc
attaaaggttatgacggcccgatcgttgagtgtgaaaaatgtggctctgaaatgcacctg
aaaatggggcgtttcggtaaatacatggcctgcaccaacgaagagtgtaaaaacacacgt
aagattttacgtaacggcgaagtggcaccaccgaaagaagatccggtgccattacctgag
ctgccgtgcgaaaaatcagatgcttatttcgtgctgcgtgacggtgctgccggtgtgttc
ctggctgccaacactttcccgaaatcgcgtgaaacgcgtgcgccactggtggaagagctt
tatcgcttccgcgaccgtctgccggaaaaactgcgttatctggccgatgcgccacagcag
gatccggaaggtaataagaccatggttcgctttagccgtaaaaccaaacagcaatatgtc
tcttcggaaaaagacggaaaggcgactggctggtcagcattttatgttgatggcaaatgg
gttgaaggaaaaaaataa

All links

Ontology (4)   
   KEGG BRITE (4)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein domain (9)   
   Pfam (9)   
All databases (18)   

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