KEGG   ENZYME: 1.1.1.108
Entry
EC 1.1.1.108                Enzyme                                 

Name
carnitine 3-dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
carnitine:NAD+ 3-oxidoreductase
Reaction(IUBMB)
carnitine + NAD+ = 3-dehydrocarnitine + NADH + H+ [RN:R02395]
Reaction(KEGG)
R02395
Substrate
carnitine [CPD:C00487];
NAD+ [CPD:C00003]
Product
3-dehydrocarnitine [CPD:C02636];
NADH [CPD:C00004];
H+ [CPD:C00080]
History
EC 1.1.1.108 created 1972
Orthology
K17735  carnitine 3-dehydrogenase
Genes
SKS: FCN78_04110
PAE: PA5386(cdhA)
PAEV: N297_5571
PAEI: N296_5571
PAU: PA14_71140
PAP: PSPA7_6172
PAG: PLES_57821
PAF: PAM18_5506
PNC: NCGM2_6160
PAEB: NCGM1900_6238
PDK: PADK2_28665
PSG: G655_28330
PRP: M062_28380
PAEP: PA1S_29110
PAER: PA1R_gp3320
PAEM: U769_29610
PAEL: T223_29570
PAES: SCV20265_6117
PAEU: BN889_05979
PAEG: AI22_04880
PAEC: M802_5569
PAEO: M801_5436
PMY: Pmen_0501
PMK: MDS_0539
PRE: PCA10_04190
PCQ: PcP3B5_28840(lcdH_1) PcP3B5_61770(lcdH_3)
PPU: PP_0302(lcdH)
PPF: Pput_0322
PPG: PputGB1_0326
PPW: PputW619_4906
PPT: PPS_0295
PPB: PPUBIRD1_0331
PPI: YSA_05609
PPX: T1E_2549(cryL1)
PPUH: B479_01940
PPUT: L483_01535
PPUN: PP4_03300
PPUD: DW66_0306
PFV: Psefu_4236
PMON: X969_27695
PMOT: X970_27310
PMOS: O165_021495
PPJ: RK21_04724
POR: APT59_00675
PSB: Psyr_2918
PFL: PFL_5754
PPRC: PFLCHA0_c57070
PPRO: PPC_5700(fadB)
PFO: Pfl01_5232
PFS: PFLU_5675
PFE: PSF113_5456(cdhA)
PFC: PflA506_4971
PFN: HZ99_15465
PPZ: H045_18695
PFB: VO64_0484 VO64_2559
PMAN: OU5_3945
PTV: AA957_16675
PCG: AXG94_13170
PVR: PverR02_29115
PAZO: AYR47_04530
POI: BOP93_24130
PFW: PF1751_v1c50980
PFF: PFLUOLIPICF710500
PFX: A7318_25075
PEN: PSEEN5183
PSTT: CH92_03720
PBA: PSEBR_a5237
PBC: CD58_27495
PPUU: PputUW4_05035(hbd)
PDR: H681_25115
PSV: PVLB_23770
PSK: U771_29375
PKC: PKB_5777(lcdH)
PCH: EY04_31850
PCZ: PCL1606_05070
PCP: JM49_02645
PFZ: AV641_01790
PALK: PSAKL28_03330
PRH: LT40_17755
PSW: LK03_04180
PPV: NJ69_17060
PSEM: TO66_29110
PSEC: CCOS191_0335(lcdH)
PPSY: AOC04_21975
PSOS: POS17_5688(fadB)
PKR: AYO71_28025
PFK: PFAS1_13520
PANR: A7J50_5400
PPSL: BJP27_13685
PSET: THL1_364
PSIL: PMA3_28045
PYM: AK972_0257
PKE: DLD99_26670
PALL: UYA_02285
PUM: HGP31_28935
POJ: PtoMrB4_04660(lcdH)
PGG: FX982_01204
ABB: ABBFA_02248(lcdH)
ABX: ABK1_1705
ABZ: ABZJ_01412
ABR: ABTJ_02453
ABD: ABTW07_1433
ABH: M3Q_1628
ABAD: ABD1_12840
ABJ: BJAB07104_01422
ABAB: BJAB0715_01435
ABAJ: BJAB0868_01370
ABAZ: P795_11120
ABK: LX00_06220
ABAU: IX87_04195
ABAA: IX88_08440
ABW: BL01_13460
ABAL: ABLAC_20940
ACC: BDGL_000609(cryL1)
ALC: OTEC02_12010
ACAL: BUM88_06605
ACD: AOLE_12420
ACW: A0J50_11000
AGU: AS4_16040
ABER: BSR55_05550
MBS: MRBBS_1827
GAI: IMCC3135_12745(lcdH_1) IMCC3135_17730(lcdH_3)
CSA: Csal_3173
HEL: HELO_2748(lcdH)
HCS: FF32_18085
HAK: KO116_02882
HAM: HALO3119
HHU: AR456_09285
HSI: BOX17_07490
HBE: BEI_1570(lcdH)
HAG: BB497_10025
HAF: C8233_00655
HALK: CUU95_07290 CUU95_12950
HVN: EI420_12650 EI420_18960
HOL: HORIV_23150
HSR: HSBAA_22100
HAXI: HAALTHF_16130n
HTT: HZS52_20030
HAA: A5892_12955
CMAI: BFX80_07130
KUS: B9G99_01585
KMA: B9H00_13575
KUY: FY550_11975
PAUR: FGL86_03175
APAC: S7S_14045
MPRI: MP3633_3289
MARS: A8C75_21920
NIK: F5I99_00755
SALN: SALB1_2554
TSN: W908_00370
THIN: CRN91_01000
PSE: NH8B_0037
BMA: BMAA0492
BMV: BMASAVP1_0689
BML: BMA10229_0985
BMN: BMA10247_A1957
BMAL: DM55_2713 DM55_4075
BMAE: DM78_2271 DM78_3551
BMAQ: DM76_2697 DM76_4772
BMAI: DM57_13055 DM57_2810
BMAF: DM51_2646 DM51_4217
BMAZ: BM44_2496 BM44_4035
BMAB: BM45_2061 BM45_4812
BPS: BPSS0568
BPM: BURPS1710b_A2130
BPL: BURPS1106A_A0762
BPD: BURPS668_A0852
BPSE: BDL_3796 BDL_692
BPSM: BBQ_2119 BBQ_5626
BPSU: BBN_2245 BBN_3968
BPSD: BBX_2633 BBX_5633
BPZ: BP1026B_I2214 BP1026B_II0628
BPQ: BPC006_I1522 BPC006_II0807
BPK: BBK_196 BBK_3923
BPSH: DR55_3274 DR55_4783
BPSA: BBU_5478 BBU_868
BPSO: X996_2881 X996_3747
BUT: X994_1340 X994_4051
BTE: BTH_II1847
BTQ: BTQ_1212 BTQ_5131
BTJ: BTJ_1221 BTJ_3759
BTZ: BTL_2456 BTL_4617
BTD: BTI_2506 BTI_5398
BTV: BTHA_2642 BTHA_5612
BTHE: BTN_2202 BTN_4256
BTHM: BTRA_2813 BTRA_3837
BTHA: DR62_2437 DR62_4305
BTHL: BG87_2704 BG87_4588
BOK: DM82_4671 DM82_766
BOC: BG90_251 BG90_5923
BUU: WS70_11100 WS70_20325
BVI: Bcep1808_3392
BVE: AK36_3369 AK36_4332
BUR: Bcep18194_B0613 Bcep18194_C7698
BCN: Bcen_3317
BCH: Bcen2424_5050
BCM: Bcenmc03_5234
BCJ: BCAM2293
BCEN: DM39_1142 DM39_5571
BCEW: DM40_4993
BCEO: I35_6184
BAM: Bamb_4458
BAC: BamMC406_4978
BMU: Bmul_3590
BMK: DM80_4975
BMUL: NP80_4950
BCT: GEM_3397
BCED: DM42_5698
BCEP: APZ15_27650
BDL: AK34_3506
BPYR: ABD05_24120
BCON: NL30_01095
BUB: BW23_3456 BW23_475
BDF: WI26_24150
BLAT: WK25_27445
BTEI: WS51_08485
BSEM: WJ12_31355
BPSL: WS57_02755 WS57_24040
BMEC: WJ16_29805
BSTG: WT74_30180
BSTL: BBJ41_25215
BGL: bglu_2g06130
BGU: KS03_5304
BUG: BC1001_4157
BGF: BC1003_5259
BGD: bgla_2g08790
BGO: BM43_4491
BYI: BYI23_B012410
BUK: MYA_3010
BUE: BRPE67_BCDS16180(lcdH) BRPE67_DCDS03790
BUL: BW21_2522 BW21_5079
BUQ: AC233_28745
BGP: BGL_2c07850(hbd1)
BPLA: bpln_2g08720
BUD: AQ610_11940 AQ610_27810
BUM: AXG89_19840
BUI: AX768_29605
BXE: Bxe_B0826
BXB: DR64_6149 DR64_7527
BPH: Bphy_3284
BPX: BUPH_00739
BPY: Bphyt_4508
BFN: OI25_6578
BCAI: K788_0002736
PARB: CJU94_25140
PHS: C2L64_26855 C2L64_44910
PTER: C2L65_21510 C2L65_27715
PGP: CUJ91_27470
PCJ: CUJ87_17610
PTS: CUJ90_20665
PCAF: DSC91_000805
PMEG: FNZ07_10555
PPK: U875_11020
PPNO: DA70_03430
PPNM: LV28_02895
PRB: X636_23680
PPUL: RO07_21760
PSPU: NA29_15330
PAPI: SG18_20725
PVE: UC34_13100
POX: MB84_17625
PFG: AB870_00170
PNR: AT302_19055
PAND: DRB87_12090
PFIB: PI93_014865
PLG: NCTC10937_02583(paaH)
CABA: SBC2_55400(lcdH_2)
BUO: BRPE64_BCDS13590
BPET: B1917_1816
BPEU: Q425_30110
BBX: BBS798_3215
BHO: D560_0587
BHM: D558_0577
BTRM: SAMEA390648704204(fadB2_2)
BGM: CAL15_12125
AXN: AX27061_4678
AXX: ERS451415_04708(paaH_5)
ADT: APT56_21550
AIS: BUW96_13125
ASW: CVS48_26040
ACHR: C2U31_15905
ACHB: DVB37_20155
PUD: G9Q38_10255
AMIM: MIM_c27310
CDN: BN940_17536
PACR: FXN63_04545
VEI: Veis_3967
VBO: CKY39_00430
VAM: C4F17_18655
HSZ: ACP92_22610
HHF: E2K99_23830
HFR: G5S34_23775
CARE: LT85_3173
DRT: Dret_0345
MLO: mlr5041
MLN: A9174_02200
MCI: Mesci_0424
MOP: Mesop_0442
MAM: Mesau_00644
MAMO: A6B35_06065
MESO: BSQ44_22650
MESW: A9K65_002130 A9K65_030975 A9K65_031125
MESM: EJ066_09380
MESP: C1M53_02995
MHUA: MCHK_6106
MJR: EB229_02235
MERD: EB233_02320
HOE: IMCC20628_02952
AAK: AA2016_1880
AMIH: CO731_02015(lcdH_2)
PHT: BLM14_08035
NIY: FQ775_14145
SME: SMc01638
SMK: Sinme_2230
SMQ: SinmeB_2074
SMX: SM11_chr1009
SMI: BN406_02074(lcdH)
SMEG: C770_GR4Chr2309
SMEL: SM2011_c01638
SMER: DU99_12605
SMD: Smed_2174
RHI: NGR_c21580
SFH: SFHH103_02054
SFD: USDA257_c45490
SIX: BSY16_549
SAME: SAMCFNEI73_Ch2520
SINO: SS05631_c23070
EAD: OV14_3671
EAH: FA04_11390
ESJ: SJ05684_c23130
EAK: EKH55_2236
EMX: FKV68_14620 FKV68_23545 FKV68_23600
ATU: Atu5344
ARA: Arad_9260
ATA: AWN88_00065
RET: RHE_PC00126
REL: REMIM1_PB00140
REP: IE4803_PD00561
REI: IE4771_PE00576
RLE: pRL100375
RLT: Rleg2_4493
RLG: Rleg_6430
RLB: RLEG3_02215
RLU: RLEG12_05415
RTR: RTCIAT899_PC04735
RHL: LPU83_pLPU83c0619
RGA: RGR602_PC01927
RHN: AMJ98_PB00183
RPHA: AMC79_PA00225
RHX: AMK02_PB00197
RHK: Kim5_PD00534
REZ: AMJ99_PA00183
RJG: CCGE525_28965
RHR: CKA34_20725
RAD: CO657_34185
NEO: CYG48_22110
NEN: NCHU2750_44850(lcdH) NCHU2750_48340
SHZ: shn_12095
OIN: IAR37_20505
OAN: Oant_2923
OAH: DR92_3581
OCH: CES85_5191(lcdH)
BIC: LMTR13_25405 LMTR13_25515 LMTR13_25660
BGQ: X265_36365
BGZ: XH91_35570
BOP: AXW83_13330
BOS: BSY19_2289
BVV: BHK69_27410
SNO: Snov_0393
STAR: G3545_09340
LNE: FZC33_26150
ANC: GBB76_11735
MAQU: Maq22A_c00775(fadB)
MEE: DA075_12480
MTEA: DK419_20345
MOC: BB934_41920
CHEL: AL346_10015
MEY: TM49_22220
MMED: Mame_03227(lcdH_3)
AALA: IGS74_01805
PSIN: CAK95_14925
NOH: G5V57_30500
SIL: SPO1436 SPO2705
SIT: TM1040_2186
RUA: D1823_04130 D1823_08990
RUT: FIU92_08815(lcdH1) FIU92_18630(lcdH2)
RMB: K529_002940
RBL: B6K69_06590
JAN: Jann_3141 Jann_3827
RDE: RD1_2523
RLI: RLO149_c020370
RPON: G3256_10600
PDE: Pden_5073
PAMI: JCM7686_pAMI6p083
PYE: A6J80_22330
PCON: B0A89_06225
PZH: CX676_17225
PARO: CUV01_06260
PAMN: pAMV3p0253(lcdH)
PARS: DRW48_03230
PKD: F8A10_00640
PPAN: ESD82_10260
DSH: Dshi_2825
PSF: PSE_4121
PGA: PGA1_c08420
PGL: PGA2_c08170
PGD: Gal_02649
PHP: PhaeoP97_00806
PPIC: PhaeoP14_00764
PHQ: D1820_17315
OAT: OAN307_c14250
OAR: OA238_c09850
OTM: OSB_08610(lcdH)
OCT: FTO60_11465
LMD: METH_13310 METH_21860
LEJ: ETW24_09935 ETW24_13955 ETW24_20715
LAQU: R2C4_04980
RED: roselon_00048 roselon_02783
PTP: RCA23_c22110 RCA23_c29140
MALG: MALG_01861
RSU: NHU_02651(lcdH)
RHM: B5V46_11125
RHC: RGUI_3129
HAT: RC74_10280
LAP: ACP90_08760
LAGG: B0E33_20835
LABR: CHH27_11755
LABP: FJ695_03425
LABT: FIU93_14315(lcdH1)
DAA: AKL17_0015
YPAC: CEW88_14120 CEW88_18195 CEW88_20150
YAN: AYJ57_16300
TPRO: Ga0080559_TMP3878
SUAM: BOO69_12390 BOO69_20405
SPSE: SULPSESMR1_00890(lcdH) SULPSESMR1_02057(lcdH)
SULZ: C1J03_07620
SULI: C1J05_06975 C1J05_14740
SULD: B5M07_09530
SPOT: G6548_12330 G6548_14585
DON: BSK21_10345
TOM: BWR18_09725
RMM: ROSMUCSMR3_03098(lcdH)
ROK: RAK1035_1992
RID: RIdsm_00641(lcdH_1) RIdsm_04073(lcdH_4) RIdsm_04439(lcdH_5)
ROM: EI983_04460 EI983_04490 EI983_14360
ROH: FIU89_04000(lcdH1)
LVS: LOKVESSMR4R_02268(lcdH)
AHT: ANTHELSMS3_03203
SAGU: CDO87_20415
THAA: CFI11_07980
GEH: HYN69_15655
TAW: EI545_14055
SALO: EF888_07895
SEDI: EBB79_03425 EBB79_05585 EBB79_22475
HML: HmaOT1_14475 HmaOT1_17990
BOO: E2K80_18725
PSEB: EOK75_06675 EOK75_14590
OCD: FHY55_12290
MARU: FIU81_05425(lcdH)
PPRU: FDP22_03430
PAED: G5B38_01460 G5B38_05430 G5B38_10265
MALU: KU6B_26090(lcdH)
TGL: HFZ77_11325
PAMO: BAR1_01820 BAR1_10915
PSHQ: F3W81_06490 F3W81_08230
PALW: PSAL_035480(lcdH_1) PSAL_036210(lcdH_2)
RBZ: B9057_03260
THAS: C6Y53_04540 C6Y53_10965
HDH: G5B40_03905
SPHK: SKP52_01085(lcdH)
SPHD: HY78_26515
SECH: B18_08840
SYB: TZ53_05555
SYA: A6768_12345
SUFL: FIL70_21970
AACE: A0U92_02205
ABQ: ABAZ39_29140
ATI: AL072_21190
AZM: DM194_13930 DM194_21840
AZZ: DEW08_26055
AOZ: HUE56_07700
TMO: TMO_1135 TMO_b0425
THAC: CSC3H3_05660 CSC3H3_23945
TII: DY252_20650
NAO: Y958_14855
FER: FNB15_08945
HTQ: FRZ44_22810 FRZ44_27550(lcdH)
HADH: FRZ61_19890(lcdH) FRZ61_24410
PGV: SL003B_0536
PSTG: E8M01_34695
BCZ: pE33L466_0384(hbd)
BCY: Bcer98_0770
BLE: BleG1_1603
OIH: OB0997
HHD: HBHAL_4278
HMN: HM131_14605
HLI: HLI_16415
VIR: X953_18040
VHL: BME96_17510
VIL: CFK37_06815
VNE: CFK40_02195
LAO: AOX59_16635
SJE: AAV35_010990
GRC: GI584_06120
RUE: DT065_16690
SALE: EPH95_16095 EPH95_16470
POF: GS400_01160
SER: SERP2360
SEP: SE0220
SEPP: SEB_00146
SEPS: DP17_1248
SSP: SSP0449
SCA: SCA_0090
SXY: BE24_09735
SXL: SXYLSMQ121_0483
SXO: SXYL_00486(lcdH)
SEQO: SE1039_21180
SSIF: AL483_10580
SCV: A4G25_07285
SNL: BJD96_02610
SKL: C7J89_03935
SARL: SAP2_05490(lcdH)
SHV: AAT16_10610
PLN: Plano_2658
PKU: AUO94_02245
PLL: I858_009430
PDG: BCM40_01820
PHC: BBI08_10690
PFAE: AJGP001_15375
SPAE: E2C16_04750
PANC: E2636_03425
KPUL: GXN76_04130
CLS: CXIVA_10660(FadB)
FPLA: A4U99_02415 A4U99_15915
CCT: CC1_14980 CC1_30800
IBU: IB211_02424c
NTH: Nther_1018
MFT: XA26_04120
TPR: Tpau_2225
SCO: SCO6297(SCBAC8D1.10c)
SALB: XNR_0008 XNR_5931
SGR: SGR_6649
SGB: WQO_01850
SVL: Strvi_1044
SRC: M271_20580 M271_34120
SALL: SAZ_35445
SLV: SLIV_06660(lcdH)
STRE: GZL_01945
SLD: T261_1153
SLC: SL103_23430
SPAV: Spa2297_03255
SNR: SNOUR_08685(lcdH)
STRD: NI25_07920
SAUO: BV401_26915
SSIA: A7J05_05620
SVU: B1H20_01420
SMAL: SMALA_4613
SLAU: SLA_7086
SALF: SMD44_07202(lcdH)
SFK: KY5_7002
SKY: D0C37_00325 D0C37_31745
SKA: CP970_05050
KIT: CFP65_0450
SATK: SA2016_4012
CIG: E7741_15035
BRX: BH708_15830
BRV: CFK39_10445
BRZ: CFK38_00275
ARS: ADJ73_05975
BLY: A2T55_08570
BLIN: BLSMQ_1403 BLSMQ_1831
NOY: EXE57_03925
NDA: Ndas_1341
NAL: B005_0601
STRR: EKD16_07875(lcdH2)
SRO: Sros_5041
SEN: SACE_3866
SACE: GIY23_13570
SACG: FDZ84_36055
SVI: Svir_16250
AMYC: CU254_19720
AMYY: YIM_28040(lcdH2)
PSEA: WY02_01635
PSEE: FRP1_10610
PSEH: XF36_09860
PSEQ: AD006_20345
PECQ: AD017_28185
PHH: AFB00_26690
PAUT: Pdca_17680(fadB_2) Pdca_35570(lcdH)
PMAD: BAY61_12365
PBOR: BSF38_02080(lcdH)
TALB: FTW19_13300
NAX: HC341_11735
 » show all
Reference
1  [PMID:4302217]
  Authors
Aurich H, Kleber HP, Sorger H, Tauchert H
  Title
[Purification and properties of carnitine dehydrogenase from Pseudomonas aeruginosa].
  Journal
Eur J Biochem 6:196-201 (1968)
DOI:10.1111/j.1432-1033.1968.tb00437.x
  Sequence
[pae:PA5386]
Reference
2  [PMID:4310279]
  Authors
Schopp W, Sorger H, Kleber HP, Aurich H.
  Title
[Kinetic studies of the reaction mechanism of carnitine dehydrogenase of Pseudomonas aeruginosa]
  Journal
Eur J Biochem 10:56-60 (1969)
DOI:10.1111/j.1432-1033.1969.tb00654.x
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.108
IUBMB Enzyme Nomenclature: 1.1.1.108
ExPASy - ENZYME nomenclature database: 1.1.1.108
BRENDA, the Enzyme Database: 1.1.1.108
CAS: 9045-45-8

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Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG REACTION (1)   
   KEGG RCLASS (1)   
Gene (17052)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (687)   
   KEGG MGENES (14041)   
   RefGene (2323)   
Protein sequence (7732)   
   UniProt (3715)   
   SWISS-PROT (17)   
   RefSeq(pep) (4000)   
DNA sequence (17091)   
   RefSeq(nuc) (15842)   
   GenBank (702)   
   EMBL (547)   
Protein domain (8)   
   InterPro (8)   
All databases (41890)   

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