KEGG ENZYME: 1.1.1.108

ENZYME: 1.1.1.108

Entry

EC 1.1.1.108 Enzyme

Name

carnitine 3-dehydrogenase

Class

Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor

Sysname

carnitine:NAD+ 3-oxidoreductase

Reaction(IUBMB)

carnitine + NAD+ = 3-dehydrocarnitine + NADH + H+ [RN:R02395]

Reaction(KEGG)

R02395

Substrate

carnitine [CPD:C00487];
NAD+ [CPD:C00003]

Product

3-dehydrocarnitine [CPD:C02636];
NADH [CPD:C00004];
H+ [CPD:C00080]

History

EC 1.1.1.108 created 1972

Orthology

K17735

carnitine 3-dehydrogenase

Genes

PAE:	PA5386(cdhA)

PAEV:

N297_5571

PAEI:

N296_5571

PAU:	PA14_71140

PAP:	PSPA7_6172

PAG:	PLES_57821

PAF:	PAM18_5506

PNC:	NCGM2_6160

PAEB:

NCGM1900_6238

PDK:	PADK2_28665

PSG:	G655_28330

PRP:	M062_28380

PAEP:

PAER:

PAEM:

PAEL:

PAES:

PAEU:

PAEG:

PAEC:

PAEO:

PMY:

PMK:

PRE:	PCA10_04190

PCQ:	PcP3B5_61770(lcdH_3)

PPU:	PP_0302(lcdH)

PPF:

Pput_0322

PPG:	PputGB1_0326

PPW:	PputW619_4906

PPT:

PPS_0295

PPB:	PPUBIRD1_0331

PPI:

YSA_05609

PPX:	T1E_2549(cryL1)

PPUH:

PPUT:

PPUN:

PPUD:

PFV:	Psefu_4236

PMON:

X969_27695

PMOT:

X970_27310

PMOS:

O165_021495

PPJ:	RK21_04724

POR:	APT59_00675

PSB:

Psyr_2918

PFL:

PFL_5754

PPRC:

PFLCHA0_c57070

PPRO:

PPC_5700(fadB)

PFO:	Pfl01_5232

PFS:

PFLU_5675

PFE:	PSF113_5456(cdhA)

PFC:	PflA506_4971

PFN:	HZ99_15465

PFW:	PF1751_v1c50980

PFF:	PFLUOLIPICF710500

PFX:	A7318_25075

PPZ:	H045_18695

PFB:

VO64_2559

PMAN:

OU5_3945

PTV:	AA957_16675

PCG:	AXG94_13170

PVR:	PverR02_29115

PAZO:

AYR47_04530

POI:	BOP93_24130

PEN:

PSEEN5183

PSTT:

CH92_03720

PBA:	PSEBR_a5237

PBC:	CD58_27495

PPUU:

PputUW4_05035(hbd)

PDR:	H681_25115

PSV:	PVLB_23770

PSK:	U771_29375

PKC:	PKB_5777(lcdH)

PCH:	EY04_31850

PCZ:	PCL1606_05070

PCP:	JM49_02645

PFZ:	AV641_01790

PALK:

PSAKL28_03330

PRH:	LT40_17755

PSW:	LK03_04180

PPV:	NJ69_17060

PSEM:

TO66_29110

PSEC:

CCOS191_0335(lcdH)

PPSY:

AOC04_21975

PSOS:

POS17_5688(fadB)

PKR:	AYO71_28025

PFK:	PFAS1_13520

PANR:

PPSL:

PSET:

PSIL:

GAI:	IMCC3135_12745(lcdH_1) IMCC3135_17730(lcdH_3)

CSA:

Csal_3173

HEL:	HELO_2748(lcdH)

HCS:	FF32_18085

HAK:	KO116_02882

HAM:

HALO3119

HHU:	AR456_09285

HSI:	BOX17_07490

HBE:	BEI_1570(lcdH)

HAG:	BB497_10025

HAF:	C8233_00655

HAA:	A5892_12955

CMAI:

BFX80_07130

KUS:	B9G99_01585

KMA:	B9H00_13575

APAC:

S7S_14045

MARS:

A8C75_21920

TSN:	W908_00370

PSE:

NH8B_0037

BMA:

BMAA0492

BMV:	BMASAVP1_0689

BML:	BMA10229_0985

BMN:	BMA10247_A1957

BMAL:

BMAE:

BMAQ:

BMAI:

BMAF:

BMAZ:

BMAB:

BPS:

BPM:	BURPS1710b_A2130

BPL:	BURPS1106A_A0762

BPD:	BURPS668_A0852

BPSE:

BPSM:

BPSU:

BPSD:

BPZ:	BP1026B_II0628

BPQ:	BPC006_II0807

BPK:

BPSH:

BPSA:

BPSO:

BUT:

BTE:	BTH_II1847

BTQ:

BTJ:

BTZ:

BTD:

BTV:

BTHE:

BTHM:

BTHA:

BTHL:

BOK:

BOC:

BVI:	Bcep1808_3392

BVE:

AK36_3369

BUR:	Bcep18194_B0613

BCN:

Bcen_3317

BCH:	Bcen2424_5050

BCM:	Bcenmc03_5234

BCJ:

BCEN:

BCEW:

BCEO:

BAM:

BAC:	BamMC406_4978

BMU:

BMK:

BMUL:

BCT:

BCED:

BCEP:

BDL:

BPYR:

BCON:

BUB:

BDF:	WI26_24150

BLAT:

BTEI:

BSEM:

BPSL:

BMEC:

BSTG:

BSTL:

BGL:	bglu_2g06130

BGP:	BGL_2c07850(hbd1)

BGU:

KS03_5304

BUG:	BC1001_4157

BGF:	BC1003_5259

BGD:	bgla_2g08790

BGO:

BM43_4491

BYI:	BYI23_B012410

BUK:

MYA_3010

BUO:	BRPE64_BCDS13590

BUE:	BRPE67_BCDS16180(lcdH)

BUL:

BW21_5079

BUQ:	AC233_28745

BPLA:

bpln_2g08720

BUD:	AQ610_27810

BXE:

Bxe_B0826

BXB:

DR64_6149

BPH:

Bphy_3284

BPX:	BUPH_00739

BPY:	Bphyt_4508

BFN:

OI25_6578

BCAI:

K788_0002736

PARB:

CJU94_25140

PHS:	C2L64_26855

PTER:

VEI:

CARE:

DRT:

MLO:

MLN:	A9174_02200

MCI:	Mesci_0424

MOP:	Mesop_0442

MAM:	Mesau_00644

MAMO:

A6B35_06065 A6B35_29570

MESO:

BSQ44_22650

MESW:

A9K65_002130 A9K65_030975 A9K65_031125

HOE:	IMCC20628_02952

AAK:	AA2016_1880

AMIH:

CO731_02015(lcdH_2)

PHT:	BLM14_08035

SME:

SMc01638

SMK:	Sinme_2230

SMQ:	SinmeB_2074

SMX:	SM11_chr1009

SMI:	BN406_02074(lcdH)

SMEG:

SMEL:

SMER:

SMD:

RHI:	NGR_c21580

SFH:	SFHH103_02054

SFD:	USDA257_c45490

SIX:

SAME:

SINO:

EAD:

EAH:	FA04_11390

ESJ:	SJ05684_c23130

ATU:

Atu5344

ARA:

Arad_9260

ATA:	AWN88_00065

RET:	RHE_PC00126

REL:	REMIM1_PB00140 REMIM1_PE00448

REI:	IE4771_PE00576

REP:	IE4803_PD00561

RLE:

pRL100375

RLT:	Rleg2_4493

RLG:

Rleg_6430

RLB:	RLEG3_02215

RLU:	RLEG12_05415

RTR:	RTCIAT899_PC04735

RHL:	LPU83_pLPU83c0619

RGA:	RGR602_PC01927

RHN:	AMJ98_PB00183

RPHA:

AMC79_PA00225

RHX:	AMK02_PB00197

SHZ:

shn_12095

OAN:

Oant_2923

OAH:

DR92_3581

OCH:	CES85_5191(lcdH)

BIC:	LMTR13_25405 LMTR13_25515 LMTR13_25660

SNO:

Snov_0393

CHEL:

AL346_10015

MEY:	TM49_22220

MMED:

Mame_03227(lcdH_3)

PSIN:

CAK95_14925

SIL:	SPO1436 SPO2705

SIT:	TM1040_2186

RMB:	K529_002940

JAN:

Jann_3827

RDE:

RD1_2523

RLI:	RLO149_c020370

PDE:

Pden_5073

PAMI:

JCM7686_pAMI6p083

PYE:	A6J80_22330

PZH:	CX676_17225

PARO:

CUV01_06260

DSH:

Dshi_2825

PGA:	PGA1_c08420

PGL:	PGA2_c08170

PGD:

Gal_02649

PHP:	PhaeoP97_00806

PPIC:

PhaeoP14_00764

OAT:	OAN307_c14250

OAR:	OA238_c09850

OTM:	OSB_08610(lcdH)

LMD:	METH_13310 METH_21860

RED:	roselon_00048 roselon_02783

PTP:	RCA23_c22110

MALG:

MALG_01861

RSU:	NHU_02651(lcdH)

RHM:	B5V46_11125

RHC:

RGUI_3129

HAT:	RC74_10280

LAP:	ACP90_08760

LAGG:

B0E33_20835

LABR:

CHH27_11755

DAA:	AKL17_0015

YPAC:

CEW88_18195 CEW88_20150

SUAM:

BOO69_12390

SPSE:

SULPSESMR1_02057(lcdH)

DON:	BSK21_10345

TPRO:

Ga0080559_TMP3878

TOM:	BWR18_09725

RMM:	ROSMUCSMR3_03098(lcdH)

LVS:	LOKVESSMR4R_02268(lcdH)

AHT:	ANTHELSMS3_03203

SAGU:

CDO87_20415

THAS:

C6Y53_04540 C6Y53_10965

GEH:	HYN69_15655

RDI:	CMV14_05565

TMO:

TMO_b0425

THAC:

CSC3H3_05660

BCZ:	pE33L466_0384(hbd)

BCY:	Bcer98_0770

BLE:	BleG1_1603

OIH:

OB0997

HHD:	HBHAL_4278

HMN:	HM131_14605

VIR:	X953_18040

VHL:	BME96_17510

VIL:	CFK37_06815

VNE:	CFK40_02195

LAO:	AOX59_16635

SJE:	AAV35_010990

SEP:

SER:

SEPP:

SEPS:

SSP:

SCA:

SXY:	BE24_09735

SXL:	SXYLSMQ121_0483

SXO:	SXYL_00486(lcdH)

SEQO:

SE1039_21180

SSIF:

AL483_10580

SCV:	A4G25_07285

SNL:	BJD96_02610

SKL:	C7J89_03935

SHV:	AAT16_10610

PLN:	Plano_2658

PKU:	AUO94_02245

PLL:	I858_009430

PDG:	BCM40_01820

PHC:	BBI08_10690

PFAE:

AJGP001_15375

CCT:

CC1_30800

FPLA:

A4U99_15915

NTH:	Nther_1018

SCO:	SCO6297(SCBAC8D1.10c)

SGR:

SGR_6649

SGB:

WQO_01850

SVL:	Strvi_1044

SALB:

XNR_0008 XNR_5931

SRC:	M271_20580 M271_34120

SALL:

SAZ_35445

SLV:	SLIV_06660(lcdH)

STRE:

GZL_01945

SLD:

T261_1153

SLC:	SL103_23430

SPAV:

Spa2297_03255

SNR:	SNOUR_08685(lcdH)

STRD:

NI25_07920

SAUO:

BV401_26915

SSIA:

A7J05_05620

SVU:	B1H20_01420

SMAL:

SMALA_4613

SALF:

SMD44_07202(lcdH)

SFK:

KY5_7002

BRX:	BH708_15830

BRV:	CFK39_10445

BRZ:	CFK38_00275

BLY:	A2T55_08570

BLIN:

NDA:

NAL:

SRO:

SEN:

SVI:	Svir_16250

AMYC:

PSEA:

PSEE:

PSEH:

PSEQ:

PECQ:

PHH:	AFB00_26690

PMAD:

BAY61_12365

AEY:	CDG81_09140

» show all

Reference

1 [PMID:4302217]

Authors

Aurich H, Kleber HP, Sorger H, Tauchert H.

Title

[Purification and properties of carnitine dehydrogenase from Pseudomonas aeruginosa]

Journal

Eur J Biochem 6:196-201 (1968)
DOI:10.1111/j.1432-1033.1968.tb00437.x

Sequence

[pae:PA5386]

Reference

2 [PMID:4310279]

Authors

Schopp W, Sorger H, Kleber HP, Aurich H.

Title

[Kinetic studies of the reaction mechanism of carnitine dehydrogenase of Pseudomonas aeruginosa]

Journal

Eur J Biochem 10:56-60 (1969)
DOI:10.1111/j.1432-1033.1969.tb00654.x

Other DBs

ExplorEnz - The Enzyme Database:

1.1.1.108

IUBMB Enzyme Nomenclature:

1.1.1.108

ExPASy - ENZYME nomenclature database:

1.1.1.108

BRENDA, the Enzyme Database:

1.1.1.108

CAS:

9045-45-8

DBGET integrated database retrieval system