KEGG   ENZYME: 1.1.1.111Help
Entry
EC 1.1.1.111                Enzyme                                 

Name
3-(imidazol-5-yl)lactate dehydrogenase;
imidazol-5-yl lactate dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
(S)-3-(imidazol-5-yl)lactate:NAD(P)+ oxidoreductase
Reaction(IUBMB)
(S)-3-(imidazol-5-yl)lactate + NAD(P)+ = 3-(imidazol-5-yl)pyruvate + NAD(P)H + H+ [RN:R04185 R04186]
Reaction(KEGG)
Substrate
(S)-3-(imidazol-5-yl)lactate [CPD:C03817];
NAD+ [CPD:C00003];
NADP+ [CPD:C00006]
Product
3-(imidazol-5-yl)pyruvate [CPD:C03277];
NADH [CPD:C00004];
NADPH [CPD:C00005];
H+ [CPD:C00080]
History
EC 1.1.1.111 created 1972
Reference
1  [PMID:4303364]
  Authors
Coote JG, Hassall H.
  Title
The role of imidazol-5-yl-lactate-nicotinamide-adenine dinucleotide phosphate oxidoreductase and histidine-2-oxoglutarate aminotransferase in the degradation of imidazol-5-yl-lactate by Pseudomonas acidovorans.
  Journal
Biochem J 111:237-9 (1969)
Reference
2  [PMID:4237631]
  Authors
Cortese R, Brevet J, Hedegaard J, Roche J.
  Title
[Identification and purification of an alpha-ketoacid aromatic reductase of Escherichia coli B]
  Journal
C R Seances Soc Biol Fil 162:390-5 (1968)
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.111
IUBMB Enzyme Nomenclature: 1.1.1.111
ExPASy - ENZYME nomenclature database: 1.1.1.111
BRENDA, the Enzyme Database: 1.1.1.111
CAS: 37250-42-3

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