| Entry |
|
|---|
| Name |
2-dehydro-3-deoxy-D-gluconate 6-dehydrogenase;
2-keto-3-deoxy-D-gluconate dehydrogenase (ambiguous);
2-keto-3-deoxygluconate dehydrogenase (ambiguous)
|
|---|
| Class |
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
|
|---|
| Sysname |
2-dehydro-3-deoxy-D-gluconate:NADP+ 6-oxidoreductase
|
|---|
| Reaction(IUBMB) |
2-dehydro-3-deoxy-D-gluconate + NADP+ = (4S,5S)-4,5-dihydroxy-2,6-dioxohexanoate + NADPH + H+ [RN: R01543]
|
|---|
| Reaction(KEGG) |
|
|---|
| Substrate |
2-dehydro-3-deoxy-D-gluconate [CPD: C00204];
NADP+ [CPD: C00006]
|
|---|
| Product |
(4S,5S)-4,5-dihydroxy-2,6-dioxohexanoate [CPD: C04471];
NADPH [CPD: C00005];
H+ [CPD: C00080]
|
|---|
| History |
EC 1.1.1.126 created 1972
|
|---|
| Reference |
|
|---|
| Authors |
PREISS J, ASHWELL G. |
|---|
| Title |
Alginic acid metabolism in bacteria. II. The enzymatic reduction of 4-deoxy-L-erythro-5-hexoseulose uronic acid to 2-keto-3-deoxy-D-gluconic acid. |
|---|
| Journal |
J Biol Chem 237:317-21 (1962) |
|---|
| Other DBs |
| ExPASy - ENZYME nomenclature database: | 1.1.1.126 |
|
|---|
