KEGG ENZYME: 1.1.1.159

ENZYME: 1.1.1.159

Entry

EC 1.1.1.159                Enzyme

Name

7alpha-hydroxysteroid dehydrogenase;
7alpha-hydroxy steroid dehydrogenase;
7alpha-HSDH

Class

Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor

Sysname

7alpha-hydroxysteroid:NAD+ 7-oxidoreductase

Reaction(IUBMB)

cholate + NAD+ = 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholan-24-oate + NADH + H+ [RN:R02792]

Reaction(KEGG)

R02792

Substrate

cholate [CPD:C00695];
NAD+ [CPD:C00003]

Product

3alpha,12alpha-dihydroxy-7-oxo-5beta-cholan-24-oate [CPD:C04643];
NADH [CPD:C00004];
H+ [CPD:C00080]

Comment

Catalyses the oxidation of the 7alpha-hydroxy group of bile acids and alcohols both in their free and conjugated forms. The Bacteroides fragilis and Clostridium enzymes can also utilize NADP+.

History

EC 1.1.1.159 created 1976, modified 1980

Pathway

ec00121

Secondary bile acid biosynthesis

Orthology

K00076

7-alpha-hydroxysteroid dehydrogenase

Genes

ECO:	b1619(hdhA)

ECJ:	JW1611(hdhA)

ECD:	ECDH10B_1752(hdhA)

EBW:	BWG_1433(hdhA)

ECOK:

ECMDS42_1289(hdhA)

ECOC:

C3026_09310

ECE:	Z2624(hdhA)

ECS:	ECs_2327(hdhA)

ECF:	ECH74115_2331

ETW:	ECSP_2183(hdhA)

ELX:	CDCO157_2160

EOI:	ECO111_2088(hdhA)

EOJ:	ECO26_2347(hdhA)

EOH:	ECO103_1759(hdhA)

ECOO:

ECRM13514_2111(hdhA)

ECOH:

ECRM13516_2013(hdhA)

ESL:

O3K_12140

ESO:

O3O_13495

ESM:

O3M_12105

ECK:	EC55989_1786(hdhA)

ECG:	E2348C_1704(hdhA)

EOK:	G2583_2013(hdhA)

ELR:	ECO55CA74_09890

ELH:

ETEC_1653

ECW:	EcE24377A_1827

EUN:	UMNK88_2078

ECP:

ECP_1563

ENA:	ECNA114_1666(hdhA)

ECOS:

EC958_1840(hdhA)

ECV:	APECO1_702(hdhA)

ECOA:

APECO78_11905

ECX:	EcHS_A1694

ECM:	EcSMS35_1580

ECY:

ECSE_1740

ECR:	ECIAI1_1670(hdhA)

ECQ:	ECED1_1819(hdhA)

EUM:	ECUMN_1909(hdhA)

ECT:	ECIAI39_1439(hdhA)

EOC:	CE10_1891(hdhA)

EBR:	ECB_01588(hdhA)

ECOB:

C3029_12445

EBL:	ECD_01588(hdhA)

EBE:	B21_01578(hdhA)

EBD:

ECBD_2026

ECI:	UTI89_C1807(hdhA)

EIH:	ECOK1_1737

ECZ:	ECS88_1666(hdhA)

ECC:	c2011(hdhA)

ELO:	EC042_1787(hdhA)

ELN:	NRG857_08110

ESE:

ECSF_1480

ECL:	EcolC_2011

EKO:	EKO11_2157

EKF:	KO11_14655(hdhA)

EAB:	ECABU_c18710(hdhA)

EDH:	EcDH1_2023

EDJ:	ECDH1ME8569_1562(hdhA)

ELU:	UM146_09060

ELW:	ECW_m1785(hdhA)

ELL:	WFL_08740(hdhA)

ELC:	i14_1831(hdhA)

ELD:	i02_1831(hdhA)

ELP:	P12B_c1464(hdhA)

ELF:	LF82_0973(hdhA)

ECOL:

LY180_08440

ECOI:

ECOPMV1_01714(hdhA)

ECOJ:

P423_08660

EAL:	EAKF1_ch4433

EMA:	C1192_04160

ESZ:	FEM44_23020(hdhA)

ERUY:

OSH18_02810(hdhA)

SFL:

SF1644

SFN:

SFy_2351

SFS:

SFyv_2405

SFT:	NCTC1_01782(hdhA)

SSN:	SSON_1541(hdhA)

SBO:	SBO_1517(hdhA)

SBC:	SbBS512_E1806

SDY:	SDY_1838(hdhA)

SDZ:	Asd1617_02472

SHQ:	A0259_12120

PSHI:

SAMEA2665130_1873(hdhA)

PATL:

KGI96_05555

ADP:	NCTC12871_00061(hdhA)

MSEP:

CEP49_01210

SACZ:

AOT14_04240

STEK:

AXG53_18805

PMEX:

H4W19_17740(hdhA)

RGL:	CS053_01945 CS053_04875(hdhA)

GHO:	AL542_12830

GKD:	K6Q96_13740(hdhA)

PPUT:

L483_14070

PPUN:

PP4_27250

PFZ:	AV641_10540

PLQ:	AA042_19770

PPSY:

AOC04_07840

PSIL:

PMA3_11740

PUM:	HGP31_20755

PPSH:

G5J76_13495

PTAE:

NCTC10697_02058(hdhA)

PCAV:

D3880_17500

PPHN:

HU825_14750

PKM:	PZ739_11550

PFOU:

OZ911_14085

PSA:

PST_0160

PSED:

DM292_18055

SDEG:

GOM96_01755

HARR:

HV822_17970

PPHA:

BVH74_17955

PCR:	Pcryo_2061

PRW:	PsycPRwf_0646

PSO:	PSYCG_11165

PUR:	AOC03_04405 AOC03_05445

PSPG:

AK823_11385

PSYG:

AK825_11820

PSYC:

DABAL43B_2359(hdhA)

PSYY:

DLE54_03375

PCIA:

Q6344_12185 Q6344_13355

PRAE:

MN210_04450

ACB:

A1S_3474

ARJ:	DOM24_05960

ACHI:

CDG60_11550

ABOU:

ACBO_29550(hdhA)

ATZ:	M5E07_09265

COLW:

A3Q33_18515

CBER:

B5D82_11330

PHA:	PSHAa2129(hdhA)

PTN:	PTRA_a2582(hdhA) PTRA_b0693(hdhA)

PNG:	PNIG_a2776(hdhA)

SNAN:

I6N98_14745

ZAL:	AZF00_13560

AFUS:

EYZ66_13050

PAQM:

E0F26_07420

RHH:	E0Z06_14935

THIP:

N838_00855(hdhA) N838_28820

TBOG:

LT988_04030(hdhA)

TWG:	Thiowin_03292(hdhA)

HPIS:

P1P91_14285

PAUR:

FGL86_03760

MSEC:

LN244_04780

MRZ:	KDW95_00775

OCE:

GU3_12620

OPE:	PU634_09790

OCM:	CBP12_06080

OPF:	CBP31_12435

CUH:	BJN34_31130

BXE:

Bxe_C0288

BXB:

DR64_8145

CTT:	CtCNB1_1310

CTES:

O987_07540

DIH:	G7047_10080

SMIO:

CATMQ487_31910(hdhA)

NET:

Neut_1072

AZI:	AzCIB_1506

AZD:	CDA09_09950

THU:	AC731_008890

THAU:

C4PIVTH_4322

THAG:

CKCBHOJB_02378

SMX:	SM11_pC0473

SMI:	BN406_04893

RGA:	RGR602_PC01386

KAI:	K32_36820(hdhA)

BME:	BMEI0405 BMEI0406

BMEL:

DK63_1019(hdhA) DK63_1020

BMI:	BMEA_A1670 BMEA_A1671

BMZ:	BM28_A1622 BM28_A1623

BMG:	BM590_A1606 BM590_A1607

BMW:	BMNI_I1556 BMNI_I1557

BMEE:

DK62_1927 DK62_1928(hdhA)

BMF:	BAB1_1634 BAB1_1635

BMB:	BruAb1_1604 BruAb1_1605

BMC:	BAbS19_I15270 BAbS19_I15280

BAA:	BAA13334_I01387 BAA13334_I01389

BABO:

DK55_1585(hdhA) DK55_1586

BABR:

DO74_303 DO74_304(hdhA)

BABT:

DK49_1343(hdhA) DK49_1344

BABB:

DK48_533 DK48_534(hdhA)

BABU:

DK53_1569(hdhA) DK53_1570

BABS:

DK51_1972 DK51_1973(hdhA)

BABC:

DO78_1490(hdhA) DO78_1491

BMS:	BR1618 BR1619

BSI:	BS1330_I1612 BS1330_I1613

BSF:	BSS2_I1570 BSS2_I1571

BSUI:

BSSP1_I1639 BSSP1_I1640

BSUP:

BSPT1_I1656 BSPT1_I1657

BSUV:

BSPT2_I1638 BSPT2_I1639

BSUC:

BSSP2_I1643 BSSP2_I1644

BMT:	BSUIS_A1676 BSUIS_A1677

BSZ:	DK67_709 DK67_710(hdhA)

BSV:	BSVBI22_A1612 BSVBI22_A1613

BSW:	IY71_07985 IY71_07990

BSG:	IY72_07725 IY72_07730

BOV:	BOV_1561 BOV_1562

BCS:	BCAN_A1655 BCAN_A1656

BSK:	BCA52141_I2599 BCA52141_I2601

BOL:	BCOUA_I1618 BCOUA_I1619

BCAR:

DK60_1627(hdhA) DK60_1628

BCAS:

DA85_07770 DA85_07775

BMR:	BMI_I1635 BMI_I1636

BPP:

BPI_I1675

BPV:	DK65_1879 DK65_1880(hdhA)

BCET:

V910_100402 V910_100403

BCEE:

V568_100447 V568_100448

BVL:	BF3285c1_1242 BF3285c1_1243

BRU:	BFS01_07770 BFS01_07775

BRJ:	BKD03_13710 BKD03_13715

BIO:	BR141012304_11076 BR141012304_11077

BOS:	BSY19_1534 BSY19_1535(hdhA)

APRA:

G3A50_13370

META:

Y590_18880

MIV:	C4E04_17885

JAV:	OXU80_25760 OXU80_25765(hdhA)

BNE:	DA69_08650

BDM:	EQG53_16165

BVY:	NCTC9239_00818(hdhA_3)

BBUL:

U0030_03425(hdhA)

SIL:

SPO3654

SIT:	TM1040_2532

RUA:	D1823_17850

RUT:	FIU92_02140(hdhA)

RCON:

K3740_02245

RUY:	NOR97_02045

JAN:

Jann_3883

RDE:

RD1_1281

RLI:	RLO149_c035010

RPON:

G3256_16665

RFU:	ROLI_036970(bacC_2)

DSH:

Dshi_0672

PGA:	PGA1_c29980

PGL:	PGA2_c27890

PGD:

Gal_00421

PHP:	PhaeoP97_00508

PPIC:

PhaeoP14_02768

PHQ:	D1820_09675

OAT:	OAN307_c05980

OAR:	OA238_c36120

OTM:	OSB_28210(fabG_6)

OCT:	FTO60_13900

LMD:	METH_02790

LEJ:	ETW24_03535

LAQU:

R2C4_14145

LEV:	ETW23_16605

LCAE:

K3721_02925

RED:	roselon_00663

CID:

P73_4196

CMAR:

IMCC12053_1256

CEH:	CEW89_10655

CBAK:

DA792_19010

MALG:

MALG_02629

CON:	TQ29_14840 TQ29_15795

YPAC:

CEW88_11930

YAN:	AYJ57_05920

TPRO:

Ga0080559_TMP1389 Ga0080559_TMP3707

PABY:

Ga0080574_TMP1631

SUAM:

BOO69_15645

SULZ:

C1J03_02495

SULI:

C1J05_01330

SULD:

B5M07_15295

SPOT:

G6548_14490

SMED:

JNX03_11455

SINL:

DSM14862_03001(fabG_9)

SFAV:

PL335_14355

SUAL:

KDD17_12820

SDUB:

R1T39_09175

SPSE:

SULPSESMR1_02760(fabG)

TOM:	BWR18_14185

RMM:	ROSMUCSMR3_02595(bacC)

ROK:	RAK1035_0580

RID:	RIdsm_00133(ydaD_1)

ROM:	EI983_09585

ROH:	FIU89_02020(fabG3)

RPEL:

N7U68_13580

AHT:	ANTHELSMS3_01579

SAGU:

CDO87_07555

THAA:

CFI11_03795

OCD:	FHY55_03165

ROT:	FIV09_01880(fabG1)

RMH:	LVO79_14210

MALU:

KU6B_50150

TGL:	HFZ77_14855

HAT:	RC74_08740

PALX:

GQA70_17690

LSAL:

KBK07_02785

LALG:

LentiSH36_00050

TRY:	QF118_07290

PLCG:

RVY76_01070

MARU:

FIU81_02760(hdhA)

RMAI:

MACH21_29470

RSP:

RSP_0684

RSH:	Rsph17029_2339

RSQ:	Rsph17025_0546 Rsph17025_4255 Rsph17025_4256

RSK:	RSKD131_2042

CAZT:

LV780_02435 LV780_21205 LV780_21210(hdhA)

RHP:	LPB142_13640

RBL:	B6K69_15135

FYT:	QF092_15135

PDE:

Pden_1754

PAMI:

JCM7686_1119

PYE:	A6J80_05285

PZH:	CX676_01685

PARO:

CUV01_13510

PARU:

CYR75_03350 CYR75_14110

PAMN:

JCM7685_2020

PMUT:

DPM13_03235

PARR:

EOJ32_09285

PAAK:

FIU66_06160

PKD:	F8A10_12490

PPAN:

ESD82_14760

PLIA:

E4191_06715

PMAU:

CP157_01787(fabG_2)

PMEH:

JWJ88_18290

PSEW:

JHW44_05550

PSAP:

JHX88_07695

PFIS:

JHX87_00825

PAEX:

JHW48_08260

PSTL:

JHW45_04430

PALP:

JHW40_15615

PVER:

E3U25_13565

PAEZ:

PAE61_10605

PALS:

PAF20_09030

PDIM:

PAF18_07175

PFEO:

E3U26_02365

PTP:	RCA23_c06370

RSU:

NHU_00279

RHM:	B5V46_02790

RHC:

RGUI_3217

RMB:	K529_012140

TSCO:

R1T40_13215

DAA:	AKL17_4764

DON:	BSK21_02145

RBZ:	B9057_11405

THW:	BMG03_16065

TEC:	AKL02_015555

LVS:	LOKVESSMR4R_00749(bacC)

GEH:	HYN69_14550

GFU:	KM031_12865

TAW:	EI545_08600

SALO:

EF888_09100

SEDI:

EBB79_18090

PPSO:

QPJ95_10035

HML:	HmaOT1_02265

BOO:	E2K80_17215

PSEB:

EOK75_11710

LIT:	FPZ52_02725

PPRU:

FDP22_05250

PAED:

G5B38_10445

MON:	G8E03_05335

PAMO:

BAR1_14065

POZ:	I0K15_13820

PALW:

PSAL_023510(bacC)

PSHQ:

F3W81_17390

PPAF:

I8N54_17130

CACT:

HZ995_04055

THAS:

C6Y53_09995

CMAG:

CBW24_02840

FAP:	GR316_00300

GCE:	KYE46_03680

GYJ:	AADW23_01850 AADW23_13020(hdhA)

NSM:	JO391_02180 JO391_19865(hdhA) JO391_19870

ACRO:

K3J57_11635

SINR:

O5O51_02995

AALK:

LGT41_0006315

AMYL:

QBD29_04895

AMAQ:

GO499_00620

RHOC:

QTA57_03370

PBAE:

P8S53_02395

RBG:	BG454_03170

LVR:	T8T21_13470

BOSG:

GKR98_15840

FAQ:	G5B39_12655

RBX:	I3V23_07285

NPP:	PP1Y_Mpl2814

NGF:	FRF71_11480

NOG:	GKE62_04200

SPHA:

D3Y57_09485

SLAN:

GV829_01765

SBD:	ATN00_02530

SPHB:

EP837_03639

SPPH:

KFK14_05365

SPHG:

AZE99_15690

SFLA:

SPHFLASMR4Y_02341(benD)

SPHY:

CHN51_05505

PARJ:

J4G78_12865

ARUE:

QQX03_09250

TFV:	IDJ81_03145

ERY:	CP97_00135

PORL:

BG023_11863

PHZ:	CHX26_05430

RMT:	IAI58_21185(hdhA)

HPY:

HP_1014

HEO:	C694_05250

HPJ:

jhp_0409

HPA:	HPAG1_0432

HPS:	HPSH_02240

HHP:	HPSH112_02435

HHQ:	HPSH169_02355

HHR:	HPSH417_02165

HPG:

HPG27_414

HPP:	HPP12_0429

HPB:	HELPY_0439

HPL:	HPB8_1130(hdhA)

HPC:	HPPC_02185

HCA:	HPPC18_02145

HPM:	HPSJM_02280

HPE:	HPELS_04580

HPO:	HMPREF4655_20677

HPI:	hp908_0449

HPQ:	hp2017_0437

HPW:	hp2018_0439

HPU:	HPCU_02500

HEF:	HPF16_0436

HPF:	HPF30_0865

HEQ:	HPF32_0876

HEX:	HPF57_0484

HPT:	HPSAT_02170

HPZ:

HPKB_0437

HPV:	HPV225_0454

HPX:	HMPREF0462_0493

HEN:	HPSNT_02330

HPH:	HPLT_02230

HEG:	HPGAM_02325

HPN:	HPIN_02030

HEP:	HPPN120_02200

HEU:	HPPN135_02215

HES:	HPSA_02180

HPYS:

HPSA20_0481

HCN:	HPB14_02110

HPD:	KHP_0420(hdhA)

HEY:

MWE_0518

HER:	C695_05255

HEI:	C730_05250

HPYA:

HPAKL117_02115

HPYK:

HPAKL86_03240

HPYO:

HPOK113_0440

HPYL:

HPOK310_0435

HPYB:

HPOKI102_02470

HPYC:

HPOKI112_02460

HPYD:

HPOKI128_02260

HPYE:

HPOKI154_02275

HPYF:

HPOKI422_02460

HPYG:

HPOKI673_02265

HPYH:

HPOKI828_02260

HPYJ:

HPOKI898_02475

HPYR:

K747_10870

HPYI:

K750_03740

HPYU:

K751_05290

HPYM:

K749_03465

HEM:	K748_01880

HEB:

U063_1219

HEZ:

U064_1223

HHE:

HH_1627

HAC:	Hac_1118(hdhA)

HMS:

HMU14020

HFE:	HFELIS_09110

HBI:	HBZC1_04430

HCE:

HCW_03695

HCM:

HCD_06040

HCP:

HCN_0775

HCB:	HCBAA847_1213

HHM:	BN341_13850

HTY:	BN2458_PEG0841

HBL:	XJ32_11090

HAD:	CDV25_07120

HET:	BBW65_03700

HCL:	NCTC13205_01179(fabL)

HWI:	A0Z60_06755

HSH:	NHP194022_15110(hdhA)

HPUL:

NCTC13154_00469(fabL)

HAIL:

ASB7_10900

WSU:

WS2222

TDN:	Suden_1227

SUA:

Saut_0922

SULN:

FJR47_04390

SULG:

FJR48_06720

SULC:

CVO_05190

SPAL:

FM071_06305

SSEI:

FJR45_04620

SBAL:

HUE88_04550

SMAS:

HUE87_07470

SMAX:

FJR03_07070

SAQT:

GJV85_05720

SKU:	Sulku_0931

SULR:

B649_07490

CJE:

Cj0807

CJB:	BN148_0807

CJJ:	CJJ81176_0828

CJU:

C8J_0758

CJN:	ICDCCJ07001_780

CJI:

CJSA_0763

CJM:

CJM1_0784

CJS:

CJS3_0855

CJP:	A911_03915

CJEJ:

N564_00786

CJEU:

N565_00830

CJEN:

N755_00827

CJEI:

N135_00852

CJER:

H730_04935

CJV:	MTVDSCj20_0816

CJY:	QZ67_00875(fabL)

CJQ:	UC78_0770(fabL)

CJL:	PJ17_03920

CJW:	PJ18_03980

CJR:

CJE0898

CJD:	JJD26997_1203

CJZ:	M635_08335

CJX:	BN867_08080

CFF:	CFF8240_0783

CFT:	CFF04554_0790

CFV:	CFVI03293_0964

CFX:	CFV97608_0847

CFZ:

CSG_12070

CAMP:

CFT03427_0773

CFP:	CR44_03930

CCV:	CCV52592_1137

CHA:	CHAB381_0584

CCO:	CCC13826_0121

CCOC:

CCON33237_1067

CLA:

CLA_0625

CLR:	UPTC16701_0627

CLM:	UPTC16712_0633

CLQ:	UPTC4110_0636

CLN:	UPTC3659_0721

CLL:	CONCH_0634

CCOL:

BN865_13120c

CCC:	G157_04865

CCQ:

N149_0749

CCF:

YSQ_05365

CCY:

YSS_04040

CCOI:

YSU_05020

CCOF:

VC76_03920(fabL)

CCOO:

ATE51_02030(fabL)

CAJ:	CIG1485E_1090

CIS:

CINS_0600

CVO:

CVOL_0619

CPEL:

CPEL_0692

CAMR:

CAQ16704_0661

CSM:	CSUB8521_0665

CSF:	CSUB8523_0753

CGRA:

CGRAC_1259

CURE:

CUREO_0896

CHYO:

CHH_0712

CHV:	CHELV3228_0529

CSPF:

CSF_1172

CPIN:

CPIN18020_0636

CCUN:

CCUN_0804

CLX:

CLAN_0896

CAVI:

CAV_0650

CHW:	A2J15_002725

CAMZ:

CVIC12175_0889

CAMY:

CSUIS_0947

COJ:

CORN_0707

CUX:	CUP3940_1162

CRX:	CRECT_1198

CGEO:

CGEO_1020

CBLA:

CBLAS_0865

CCOR:

CCORG_0774

CARM:

CARM_0690

CMUC:

CMCT_0879

CSHO:

CSHOW_0956

CINF:

CINF_0722

CNV:	CNZW441b_0709

CVU:	CVULP_0467

CDEV:

CIGN_0738

SDL:

Sdel_1059

SBA:	Sulba_1205

SMUL:

SMUL_1469

SHAL:

SHALO_1439

SULS:

Sdiek1_1516

SULJ:

SJPD1_1446

SULT:

FA592_13535

ABU:

Abu_0873

ABT:

ABED_0825

ABL:	A7H1H_0883

ASK:	EI285_02720

ATP:

ATR_1094

ACIB:

ACBT_1565

ACRE:

ACRYA_0869

ALAN:

ALANTH_1036

AFC:	AFAEC_1436

ATHR:

ATH_1317

ANT:	Arnit_2128

AELL:

AELL_1015

AAQI:

AAQM_0898

ASUI:

ASUIS_1701

ACLO:

ACLO_0968

AVP:	AVENP_2042

ADZ:	ADFLV_1043

ARC:

ABLL_1104

PACO:

AACT_1128

APOC:

APORC_1370

AROS:

NJU99_10140

ALK:

ALEK_2461

ALP:	LPB137_09490

AHS:	AHALO_1779

AMYT:

AMYT_1854

AMAR:

AMRN_1809

ACAA:

ACAN_1828

AMOL:

AMOL_1854

APAI:

APAC_1684

HBV:

ABIV_1642

HEBR:

AEBR_1977

AANA:

AANAER_1925

HYO:

NNO_1099

HTM:	RZR91_07610

HCJ:

HCR_01700

NSA:	Nitsa_0918

SUN:

SUN_0808

SLH:	YH65_07615

SINU:

IMZ28_07650

SMAB:

LN246_03900

NIS:

NIS_0698

NAM:

NAMH_0962

NAP:	C3L23_04980

CMED:

FE773_05965

CPAF:

C6V80_05200

PAUU:

E8A73_045650

CSO:

CLS_38520

PHX:	KGNDJEFE_01400

AARG:

Aargi30884_01080

ABSI:

A9CBEGH2_02660

MTU:

Rv0927c

MTV:	RVBD_0927c

MTC:

MT0954

MRA:

MRA_0935

MTF:	TBFG_10945

MTB:	TBMG_03062

MTK:	TBSG_03082

MTZ:	TBXG_003042

MTG:	MRGA327_05815

MTI:	MRGA423_05825

MTE:	CCDC5079_0856

MTUR:

CFBS_0975

MTL:	CCDC5180_0847

MTO:	MTCTRI2_0951

MTD:

UDA_0927c

MTN:	ERDMAN_1028

MTJ:	J112_05005

MTUB:

MT7199_0946

MTUE:

J114_04965

MTX:	M943_04860

MTUL:

TBHG_00912

MTUT:

HKBT1_0975

MTUU:

HKBT2_0976

MTQ:	HKBS1_0975

MBO:	BQ2027_MB0950C

MBB:

BCG_0979c

MBT:

JTY_0949

MBM:	BCGMEX_0950c

MBK:	K60_009920

MBX:

BCGT_0739

MAF:

MAF_09360

MMIC:

RN08_1034

MCE:	MCAN_09271

MCQ:	BN44_11019

MCV:	BN43_20397

MCX:	BN42_20736

MCZ:	BN45_20227

MORY:

MO_000990

MPA:	MAP_0871c MAP_1787c MAP_3222c

MAO:	MAP4_0566 MAP4_2989

MAVI:

RC58_02750 RC58_14840

MAVU:

RE97_02755 RE97_14865

MAV:	MAV_1046 MAV_2460 MAV_4056

MIT:	OCO_09170 OCO_10850 OCO_18870 OCO_24570 OCO_39040

MIA:	OCU_09210 OCU_19070 OCU_24440 OCU_39010

MID:	MIP_01531 MIP_02649 MIP_03394 MIP_05898

MYO:	OEM_09340 OEM_23040 OEM_39580

MCHI:

AN480_05765 AN480_12375 AN480_20525

MIR:	OCQ_09300 OCQ_17480 OCQ_23110 OCQ_40190

MMAL:

CKJ54_04565 CKJ54_11155 CKJ54_18565

MMAN:

MMAN_15090 MMAN_52540 MMAN_56040

MSER:

MTY59_02540 MTY59_28500 MTY59_40270

MSA:	Mycsm_05330

MUL:	MUL_2481 MUL_4442

MMI:	MMAR_1395 MMAR_4581

MMAE:

MMARE11_13620 MMARE11_43930

MLI:	MULP_01566 MULP_04798

MPSE:

MPSD_15830 MPSD_47320

MSHO:

MSHO_19980 MSHO_21330

MMC:	Mmcs_4362 Mmcs_4414 Mmcs_4606

MKM:	Mkms_4448 Mkms_4501 Mkms_4694

MJL:	Mjls_4742 Mjls_4795 Mjls_4989

MMM:	W7S_04535 W7S_11870 W7S_19515

MKN:	MKAN_09160 MKAN_22075

MYV:	G155_06610

MYE:	AB431_08675 AB431_14210 AB431_24220

MHAD:

B586_06155

MDX:	BTO20_29220

MSHG:

MSG_01350 MSG_04115

MFJ:	MFLOJ_03030 MFLOJ_07660 MFLOJ_20240 MFLOJ_45100

MSTO:

MSTO_22680 MSTO_49310

MSIM:

MSIM_11130 MSIM_34450 MSIM_47800

MSAK:

MSAS_24690 MSAS_50450

MKU:	I2456_07405 I2456_21845 I2456_22895

MLW:	MJO58_07015 MJO58_22955

MXE:	MYXE_12230

MNV:	MNVI_08290 MNVI_29110

MPAG:

C0J29_08085 C0J29_25255

MNM:	MNVM_09660

MGOR:

H0P51_07035 H0P51_23535

MCOO:

MCOO_22990 MCOO_25910 MCOO_46140

MBAI:

MB901379_04011(hdhA_1)

MSEO:

MSEO_01620 MSEO_17320 MSEO_29140

MHEK:

JMUB5695_01155 JMUB5695_02813 JMUB5695_03557

MGAU:

MGALJ_02830 MGALJ_34450 MGALJ_34980

MLJ:	MLAC_04320

MBRD:

MBRA_24070 MBRA_25160

MSHJ:

MSHI_01040

MMAM:

K3U93_06770 K3U93_19990

MSPG:

F6B93_18550

MOT:	LTS72_02290 LTS72_18165

MPAA:

MKK62_04415 MKK62_09505 MKK62_25320

MKY:	IWGMT90018_14940 IWGMT90018_52780

MADI:

A7U43_08545

MWU:	PT015_13090 PT015_18320

MYW:	BVC93_01370 BVC93_06905

MSM:	MSMEG_5584

MSG:	MSMEI_5435

MSB:	LJ00_27615

MSN:	LI99_27620

MSH:	LI98_27625

MVA:	Mvan_4921 Mvan_4971

MGI:	Mflv_1776 Mflv_1825

MSP:	Mspyr1_11610 Mspyr1_12250

MCB:	Mycch_4294

MNE:	D174_22695

MYN:	MyAD_22255

MFT:	XA26_12480 XA26_13200

MPHL:

MPHLCCUG_00880(hdhA_2) MPHLCCUG_03862(kduD_2)

MVQ:	MYVA_4738 MYVA_4790

MLL:	B1R94_20595 B1R94_23510

MRH:	MycrhN_2704 MycrhN_3273 MycrhN_6233

MTHN:

4412656_03807(hdhA_1) 4412656_04008(hdhA_2)

MHAS:

MHAS_03412 MHAS_03449

MDU:	MDUV_09750 MDUV_52070 MDUV_52540

MCHT:

MCHIJ_23070 MCHIJ_48410

MAUU:

NCTC10437_04635(hdhA_2)

MMAG:

MMAD_45500

MMOR:

MMOR_15270 MMOR_15800

MFX:	MFAL_36340

MAIC:

MAIC_09170 MAIC_14680

MIJ:	MINS_40180

MALV:

MALV_45780

MTY:	MTOK_27160 MTOK_37210

MPSC:

MPSYJ_19430

MARZ:

MARA_48920 MARA_51280

MGAD:

MGAD_21190 MGAD_33320 MGAD_34180

MHEV:

MHEL_31390 MHEL_38840

MSAR:

MSAR_02520 MSAR_07970

MANY:

MANY_00360 MANY_29580

MAUB:

MAUB_41170

MPOF:

MPOR_50370

MPHU:

MPHO_28370

MMUC:

C1S78_004160

MMAT:

MMAGJ_09730

MBOK:

MBOE_23810

MFG:	K6L26_07165 K6L26_07430

MSEI:

MSEDJ_32370 MSEDJ_59130

MFLV:

NCTC10271_00850(hdhA_2) NCTC10271_01431(fabG_10)

MCEE:

MCEL_41720 MCEL_47180

MMON:

EWR22_23570 EWR22_23925

MGO:	AFA91_12725

MHOL:

K3U96_04735 K3U96_07800

MSEN:

K3U95_23390 K3U95_23635

MPAE:

K0O64_08190 K0O64_23920

MRF:	MJO55_22375

MDF:	K0O62_23940

MCRO:

MI149_09195 MI149_24345

MGRO:

FZ046_00800 FZ046_02410

MAUS:

JN090_24365 JN090_24655

MKR:	MKOR_38740

MPAK:

MIU77_03490

MAB:

MAB_4632

MMV:	MYCMA_2556

MABB:

MASS_4659

MABL:

MMASJCM_4688

MCHE:

BB28_23630

MIZ:	BAB75_26110

MSTE:

MSTE_04802

MSAO:

MYCSP_21595

MSAL:

DSM43276_04463(hdhA_2)

MJD:	JDM601_0876

MTER:

4434518_00836(hdhA_1)

MMIN:

MMIN_25030

MHIB:

MHIB_03680

MHER:

K3U94_04745

MVM:	MJO54_04910

NFA:

NFA_24670

NFR:	ERS450000_01631(hdhA_1)

NCY:	NOCYR_3703(hdhA)

NBR:	O3I_017480

NNO:	NONO_c04060

NSL:	BOX37_16220

NSR:	NS506_00363

NTP:	CRH09_02755

NOZ:	DMB37_39175

NOD:	FOH10_29365

NAH:	F5544_20265

NAD:	NCTC11293_03330(hdhA_1)

NWL:	NWFMUON74_03900(hdhA)

NIE:	KV110_19495

NTC:	KHQ06_08160

NHU:	H0264_03250

NYA:	LTV02_29475

NGP:	LTT66_36145

NSPU:

IFM12276_37460

NYU:	D7D52_03940

ROP:	ROP_pROB02-00930

ROZ:	CBI38_27615

WHR:	OG579_10725

GBR:

Gbro_4568

GPO:	GPOL_c04750

GOR:

KTR9_4545

GTA:	BCM27_23790

GOC:	CXX93_12045

GRU:	GCWB2_22720(hdhA)

GOM:	D7316_03070

GAV:	C5O27_05690

GOD:	GKZ92_21735

GOS:	QAD21_22530

GOJ:	GR168_21615

GJI:	H1R19_21880

GOI:	LK459_10555

GHN:	MVF96_22570

GAMI:

IHQ52_05170

GMG:	NWF22_12320

GSI:	P5P27_10065

SPIN:

KV203_10140

NCA:

Noca_0427

NDK:	I601_1650(rhlG)

NBE:	Back2_27110

NANO:

G5V58_24635

NARO:

CFH99_02805

NPI:	G7071_03055

NPC:	KUV85_15470

NMAR:

HPC71_01665

NFC:	KG111_01600

NBI:	SHK19_01385

PSIM:

KR76_03205

AEB:	C6I20_03170

AMAZ:

LUW76_08500

ACIR:

OG979_32740

SPIQ:

OHA34_09660

ACTQ:

OG417_42060

AMD:	AMED_2305(hdhA)

AMN:

RAM_11735

AMM:	AMES_2279(hdhA)

AMZ:	B737_2280(hdhA)

AOI:	AORI_5625(hdhA)

AJA:	AJAP_11350

AAB:	A4R43_15340

AMYY:

YIM_15175(hdhA2)

AORI:

SD37_27485

AACD:

LWP59_30390

APRT:

MUY14_24935

AROO:

NQK81_38600

ATHM:

L1857_28150

ARHD:

VSH64_00720

AMOG:

QRX60_25245

ACYN:

ORV05_05970

ACOR:

LCL61_16905

KUT:	JJ691_19340(hdhA)

KPHY:

AOZ06_43315

PMAD:

BAY61_23920

ASG:	FB03_02480

JCY:	M6B22_17830

ABAI:

IMCC26256_11538

AYM:	YM304_02910 YM304_04710

AQZ:	KSP35_14430

IAM:	HC251_22620

IMA:	PO878_20335

DHI:	LH044_15070

LSC:	KIK02_24535(hdhA) KIK02_24540

CYT:

cce_2593

CYC:	PCC7424_0224

CYJ:	Cyan7822_5662

PPSU:

NO713_01292(hdhA) NO713_01293(hdhA)

LFS:	HFV01_24820 HFV01_24825(hdhA)

LIX:	H2674_02365(hdhA) H2674_02370

SCS:	Sta7437_4706 Sta7437_4710

DSW:	QR90_06115

DEIN:

DAAJ005_08310

DRB:	N0D28_05190

FVA:	FV113G1_21970(hdhA)

FUL:	C4N20_16245

FMO:	C4N19_06120

FHO:	H9Q81_05130

CSOM:

MKD34_09355

CPOR:

BED41_06355

BIS:	DXK01_008775

MGOD:

E7746_00535 E7746_00540

BVIR:

I6J59_17315

BFH:	F1611_10950

AIT:	AI2BBH_15620(hdhA)

RBC:	BN938_2809 BN938_2810

PEP:	AQ505_11130

PGJ:	QG516_04475

HYP:	A0257_02490

FGC:	LNP27_09770

ASL:	Aeqsu_0778

AEV:	EI546_09960

OCI:	FEZ18_04625

BIA:	GMA17_14425

HWS:	RNZ46_04705

ORH:	Ornrh_2066

ORI:	Q785_10220

CSAL:

NBC122_01959(hdhA)

CJG:	NCTC13459_00290(hdhA)

CANT:

NCTC13489_01390(hdhA)

KFA:	Q73A0000_08775

EFAL:

FH779_06390

SUL:	SYO3AOP1_0187

» show all

Reference

1 [PMID:786279]

Authors

Haslewood ES, Haslewood GA.

Title

The specificity of a 7 alpha-hydroxy steroid dehydrogenase from Escherichia coli.

Journal

Biochem J 157:207-10 (1976)
DOI:10.1042/bj1570207

Reference

2 [PMID:6945134]

Authors

MacDonald IA, Roach PD.

Title

Bile induction of 7 alpha- and 7 beta-hydroxysteroid dehydrogenases in Clostridium absonum.

Journal

Biochim Biophys Acta 665:262-9 (1981)
DOI:10.1016/0005-2760(81)90011-4

Reference

3 [PMID:4581498]

Authors

Macdonald IA, Williams CN, Mahony DE.

Title

7Alpha-hydroxysteroid dehydrogenase from Escherichia coli B: preliminary studies.

Journal

Biochim Biophys Acta 309:243-53 (1973)
DOI:10.1016/0005-2744(73)90022-3

Reference

4 [PMID:236764]

Authors

Macdonald IA, Williams CN, Mahony DE, Christie WM.

Title

NAD- and NADP-dependent 7alpha-hydroxysteroid dehydrogenases from bacteroides fragilis.

Journal

Biochim Biophys Acta 384:12-24 (1975)
DOI:10.1016/0005-2744(75)90091-1

Other DBs

ExplorEnz - The Enzyme Database:

1.1.1.159

IUBMB Enzyme Nomenclature:

1.1.1.159

ExPASy - ENZYME nomenclature database:

1.1.1.159

BRENDA, the Enzyme Database:

1.1.1.159

CAS:	39361-64-3

DBGET integrated database retrieval system