KEGG ENZYME: 1.1.1.163

ENZYME: 1.1.1.163

Entry

EC 1.1.1.163 Enzyme

Name

cyclopentanol dehydrogenase

Class

Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor

Sysname

cyclopentanol:NAD+ oxidoreductase

Reaction(IUBMB)

cyclopentanol + NAD+ = cyclopentanone + NADH + H+ [RN:R02553]

Reaction(KEGG)

R02553;
(other) R02229

Substrate

cyclopentanol [CPD:C02020];
NAD+ [CPD:C00003]

Product

cyclopentanone [CPD:C00557];
NADH [CPD:C00004];
H+ [CPD:C00080]

Comment

4-Methylcyclohexanol and cyclohexanol can also act as substrates.

History

EC 1.1.1.163 created 1976

Pathway

ec00930

Caprolactam degradation

Orthology

K17754

cyclopentanol dehydrogenase

Genes

RBD:

ALSL_0416

PPJ:	RK21_02868

POL:

Bpro_5564

AJS:

Ajs_2100

ADK:	Alide2_4312

HPSE:

HPF_13115(cpnA)

NAF:	GQ61_01095

PLA:

Plav_1760

RUT:	FIU92_22365(cpnA2)

CON:	TQ29_18920

LABT:

FIU93_30975(cpnA)

SUAM:

BOO69_22550

SPSE:

SULPSESMR1_04139(cpnA)

SULD:

B5M07_18390

PABY:

Ga0080574_TMP217

LVS:	LOKVESSMR4R_03945(cpnA)

MALU:

KU6B_59940

MHOS:

CXR34_00710

PMO:

Pmob_0729

DTN:	DTL3_0723(cpnA)

» show all

Reference

1 [PMID:4349113]

Authors

Griffin M, Trudgill PW.

Title

The metabolism of cyclopentanol by Pseudomonas N.C.I.B. 9872.

Journal

Biochem J 129:595-603 (1972)
DOI:10.1042/bj1290595

Reference

2 [PMID:12406764]

Authors

Iwaki H, Hasegawa Y, Wang S, Kayser MM, Lau PC.

Title

Cloning and characterization of a gene cluster involved in cyclopentanol metabolism in Comamonas sp. strain NCIMB 9872 and biotransformations effected by Escherichia coli-expressed cyclopentanone 1,2-monooxygenase.

Journal

Appl Environ Microbiol 68:5671-84 (2002)
DOI:10.1128/AEM.68.11.5671-5684.2002

Sequence

[ag:BAC22653]

Other DBs

ExplorEnz - The Enzyme Database:

1.1.1.163

IUBMB Enzyme Nomenclature:

1.1.1.163

ExPASy - ENZYME nomenclature database:

1.1.1.163

BRENDA, the Enzyme Database:

1.1.1.163

CAS:	37364-12-8

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