Entry
Name
D-xylose 1-dehydrogenase (NADP+, D-xylono-1,5-lactone-forming);
D-xylose (nicotinamide adenine dinucleotide phosphate) dehydrogenase (ambiguous);
D-xylose-NADP dehydrogenase (ambiguous);
D-xylose:NADP+ oxidoreductase (ambiguous);
D-xylose 1-dehydrogenase (NADP) (ambiguous)
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
D-xylose:NADP+ 1-oxidoreductase (D-xylono-1,5-lactone-forming)
Reaction(IUBMB)
D-xylose + NADP+ = D-xylono-1,5-lactone + NADPH + H+ [RN:
R01430 ]
Reaction(KEGG)
Substrate
Product
Comment
The enzyme, characterized from pig arterial vessels and eye lens, also acts, more slowly, on L-arabinose and D-ribose. cf. EC
1.1.1.424 , D-xylose 1-dehydrogenase (NADP+, D-xylono-1,4-lactone-forming).
History
EC 1.1.1.179 created 1982, modified 2020
Pathway
ec00040 Pentose and glucuronate interconversions
Orthology
K00078 dihydrodiol dehydrogenase / D-xylose 1-dehydrogenase (NADP)
K14273 D-xylose 1-dehydrogenase (NADP+, D-xylono-1,5-lactone-forming)
Genes
TVP : 118833309 118839742(DHDH)
CCAY : 125627899 125628450
CPIC : 101949641 101952305
CABI : 116840048 116840080(DHDH)
ACS : 100560732 100560929 100561324 100562900
ASAO : 132768759 132777928 132777930 132777931 132779385
PVT : 110078474 110078540 110078568
SUND : 121933340 121933341 121933342 121933344
VKO : 123032094 123032205 123032207
PMUA : 114582606 114582681 114582780
PRAF : 128399991 128400112 128400814
ZVI : 118094926 118095810 118095891
GJA : 107116584 107116602 107116603
XLA : 108697264 444539(dhdh-like.1.L)
XTR : 100145807(dhdh) 448579(dhdh)
BBUF : 121001904 121001919
BGAR : 122926720 122928638
DRE : 406433(dhdh.1) 449558(dhdh.2)
SRX : 107709394 107712874 107713116
SANH : 107665090 107665427 107665437 107668471
SGH : 107553352 107595342(dhdh)
CCAR : 109063738(dhdh) 109075356
CAUA : 113061390 113061391 113090243 113118075 113118076
CGIB : 127934520 127934522 127977618 127977619 127977620 127977621
PTET : 122342436(dhdh.2) 122343217(dhdh.1)
OMC : 131523912(dhdh.2) 131524552(dhdh.1)
PPRM : 120487591(dhdh.1) 120487595(dhdh.2)
MAMB : 125254692(dhdh.1) 125254746(dhdh.2)
CIDE : 127499721 127499723 127500140 127500141
CERY : 137022985(dhdh.1) 137023492(dhdh.2)
MASI : 127416617 127416618 127447472
AMEX : 103045107(dhdh.2) 103045417
CMAO : 118802349 118818299(dhdh.2) 118818428(dhdh.1)
CHAR : 105888960 105903492(dhdh.2) 105908024
TRU : 101067668 101068481 101068704
TFS : 130515143(dhdh.2) 130517575 130533700
TNG : GSTEN00000746G001 GSTEN00012065G001
TBEN : 117471664(dhdh.1) 117471748 117471749 117482636
PGEO : 117461271 117463822 117466216(dhdh.1) 117466243 117466532 117466910
GACU : 117538392 117549146 117549147 117549148(dhdh.2) 117549149
EMAC : 134863260 134863261(dhdh.2) 134863439
ELY : 117251231(dhdh.2) 117257557
EFO : 125899300(dhdh.2) 125899307(dhdh.1) 125899715
PLEP : 121944994(dhdh.2) 121945624(dhdh.1) 121949449
GAT : 120831814(dhdh.2) 120834169
AFB : 129104831 129106486(dhdh.1) 129107127
PSWI : 130192209(dhdh.2) 130192210
CUD : 121513714 121522252 121523339(dhdh.2)
ALAT : 119017704 119017706 119018266 119026305
ONL : 100699617(dhdh) 100709652 109202511
OAU : 116325505 116325587(dhdh.2)
CSAI : 133421563 133421574 133421584(dhdh.1)
XMA : 102230657 102231180 102231435
XCO : 114142662 114143656 114143657
XHE : 116718058 116718060 116718061 116718062
PRET : 103462676 103462677 103462679 103462745
PMEI : 106913099 106913443 106922157 106922160
GAF : 122819685 122819690 122819711
PPRL : 129364005 129364006 129364007 129364009 129364011
CTUL : 119795117 119795140 119795142(dhdh.1)
NFU : 107381267(dhdh) 107381268
KMR : 108240245 108240257 108240258
ALIM : 106529988 106530000
AOCE : 111567618 111571639 111571640 111571659
MCEP : 125005267 125005268 125005446 125005592
CSEM : 103378996 103378997
SSEN : 122772624 122772831
HHIP : 117757207 117759290(dhdh.2)
HSP : 118105178(dhdh.2) 118110304(dhdh.1)
PPLT : 128441908(dhdh.1) 128454766(dhdh.2)
SMAU : 118301866(dhdh.2) 118301867(dhdh.1)
SDU : 111218641 111221353 111222353
SLAL : 111649505 111649507 111671508
XGL : 120794833(dhdh.1) 120801532
SSCV : 125967411 125967412 125967413 125967414
SBIA : 133498138 133498139
PEE : 133397611 133397618 133399425
PTAO : 133474189 133474190
BPEC : 110156372 110175360 110175496
BSPL : 114851776 114851777 114852232 114852789
SJO : 128358291(dhdh.2) 128360487 128367567
SASA : 100196772(dhdh) 106586438 106587215
STRU : 115160969 115167315 115167316
OTW : 112235746 112235761 112238788 112264191
OMY : 110520289 110526353 110526354(dhdh.2)
ONE : 115112200 115112529 115115747
OKI : 109887167 109887179 109902841
SALP : 111969572 111974720 111974721 111977378
SNH : 120025366 120036864 120036866 120057905
CCLU : 121536318 121582302(dhdh.2)
AANG : 118227383(dhdh.2) 118227384 118227424
ARUT : 117429242 117963168
BBEL : 109467398 109467399 109467407 109473215 109482310
SCLV : 120333416 120333425
SPU : 100891256 581125 581189 583996 588939
LPIC : 129271550 129282514 129282563 129282591 129283043
APLC : 110979612 110982584 110989501
ARUN : 117295431 117295528 117295529
DME : Dmel_CG13280(CG13280) Dmel_CG3597(CG3597) Dmel_CG3609(CG3609)
DER : 6541366 6541604 6547628
DSE : 6613087 6613088 6614431
DSI : Dsimw501_GD11964(Dsim_GD11964) Dsimw501_GD22839(Dsim_GD22839) Dsimw501_GD22840(Dsim_GD22840)
DYA : Dyak_GE13162 Dyak_GE15118 Dyak_GE15120
DSR : 110184938 110187287 110187308
DPO : 4816794 4817398 4817478
DPE : 6589241 6589434 6589435
DMN : 108161945 108162652 108163513
DWI : 6641896 6641897 6643528 6644481
DMO : Dmoj_GI17180 Dmoj_GI17186 Dmoj_GI17187
DAZ : 108609472 108611285 108620500
DNV : 108657724 115562357 115562360
DHE : 111595497 111595504 111601181
CCAT : 101459973 101460501 105664445
BOD : 106627582 106627594 106627595
BDR : 105230783 105230786 105230788
RZE : 108353932 108363144 108363146
AOQ : 129247680 129247681 129249213
ECOE : 129939640 129949767 129950130
CLON : 129606129 129612267 129612763
ACOZ : 120955603 120958717
AARA : 120902304 120903729
AMER : 121596412 121596856
ASTE : 118512038 118512580
AFUN : 125763959 125766147
AMOU : 128300696 128301195
AALI : 118457812 118459647
AALB : 109398262 109419782 109420591 115255013
ASUA : 134212955 134217271
CQU : CpipJ_CPIJ000841 CpipJ_CPIJ014580
CPII : 120413507 120418645
CNS : 116338110 116338203 116341595
BCOO : 119073281 119075711 119076382 119077405 119078292 119078293 119079754
BAFF : 126917848 126927394 126927654 126927655
BPAS : 132907531 132907532
PBAR : 105434330 105434331
VCAN : 122406943 122409869
ATD : 109599316 109599317 109599880 109607163 109607176
APLN : 108733592 108742036
PPYR : 116159525 116160058 116160693
BMOR : 101739041 101744141
BMAN : 114246311 114252054
MSEX : 115443738 115448674 119188489
DPL : KGM_215754 KGM_215781
BANY : 112044257 112052102 112052103
NIQ : 126772379 126772641 126781878
VCD : 124532658 124543727 124543812 124543885
MCIX : 123657672 123669943
PMAC : 106709317 106717577
PPOT : 106099353 106100802
PRAP : 111003825 111003869
PBX : 123715934 123716313 123716601
PNAP : 125054461 125063549
CCRC : 123697221 123700518 123701785
LSIN : 126966606 126977291
AAGE : 121730491 121730536
HAW : 110377761 110377790 110378531
HZE : 124633408 124634935 124635327
TNL : 113496171 113501943 113502165
SLIU : 111352846 111352965 111353256 111356690
OFU : 114351674 114351913 114357580
ATRA : 106140085 106140142 106140167
PGW : 126369686 126373175 126373382 126373422 126378668
LGLY : 125225755 125235956
AGS : 114122663 114122664 114131068
ACOO : 126836125 126837403
HHAL : 106677376 106679661 106685476 106685484
TPAL : 117645221 117653083
SGRE : 126268231 126281694 126282002
FCD : 110848466 110851368 110851432 110853947 110861155
PJA : 122266417 122266420 122267624
PCHN : 125024952 125048036
PMOO : 119573195 119576301
PCLA : 123746909 123746911 123746912
PTRU : 123506622 123506623 123511170
RSAN : 119393955 119394807
PTEP : 107439493 107455902 107456420 122268241
ABRU : 129965376 129980858
PMEO : 129584996 129585026 129597062 129597732 129597951 129598052 129598676 129601609
PCAN : 112559213 112560362 112560510
GAE : 121368040 121368041 121368042
HRF : 124113678 124113682 124113684 124142983
CANU : 128180732 128180734 128180735 128180736
MCAF : 127723915 127731928 127735692
MMER : 123535820 123536383 123536673 123555691
RPHI : 132733099 132738725 132758982
DPOL : 127835852 127845338 127846476
MAEA : 128219413 128220609 128220610 128220612 128220613
OBI : 106867507 106872773 106873778 106873779 106873780 106877994
OSN : 115218237 115218278 115218279 115218305 115218360 115218450 115218668
LJP : 135463429 135463511 135463514
LAK : 106160733 106174125 106174127 106174128 106181072
LLON : 135492722 135492818 135501796 135503176 135503181
FGR : FGSG_03001 FGSG_11142
FPU : FPSE_02237 FPSE_02878
TATV : 25785682(TrAtP1_010681)
TASP : 36609706(TrAFT101_009383)
PTRR : 6341154(PtrM4_065200)
CDEP : 91089596(L203_105387)
KMG : 30160245(I203_104622)
KNE : 92179066(IAR55_001807) 92180922(IAR55_003664)
CCAC : CcaHIS019_0405350(CcaverHIS019_0405350)
TPS : THAPSDRAFT_23184 THAPSDRAFT_36572
AAF : AURANDRAFT_18834 AURANDRAFT_20106 AURANDRAFT_72519
PIF : PITG_14355 PITG_14356 PITG_14357 PITG_14358 PITG_18534 PITG_18535 PITG_18536 PITG_18537
PSOJ : PHYSODRAFT_327667 PHYSODRAFT_327668 PHYSODRAFT_496155
EHX : EMIHUDRAFT_435339 EMIHUDRAFT_436368
MISZ : MishRS11D_44800(socC)
AEL : NCTC12917_01967(afr)
BKW : BkAM31D_16055(afr_2)
ACOP : RI196_02215 RI196_17190
GRC : GI584_08365 GI584_19695
BLEN : NCTC4824_03507(afr_8)
GYM : GYMC10_2308 GYMC10_4046
PPOL : X809_04420 X809_10930
PTA : HPL003_12505 HPL003_18945
PSON : JI735_06815 JI735_24685
PPEO : ABE82_04575 ABE82_10775
PXL : BS614_15630 BS614_29785
PIB : BBD41_03590 BBD41_25265
PKB : B4V02_14695 B4V02_20495
PLW : D5F53_10085 D5F53_18125
PPSC : EHS13_09180 EHS13_26525 EHS13_28620
PBAC : HUB98_13150 HUB98_28585
PRZ : GZH47_01950 GZH47_25890
PLYC : GXP70_14320 GXP70_21825
PMAH : PTQ21_01220 PTQ21_17150
SPAE : E2C16_10370 E2C16_10420
VPY : HZI73_09630 HZI73_22155
LCRE : Pla8534_20100(afr_4)
SNEP : Enr13x_53370(afr_10)
CCOP : Mal65_10680(afr_1) Mal65_25570(afr_3)
FPEC : Q1W71_03840 Q1W71_07710
» show all
Taxonomy
Reference
1
Authors
Wissler JH.
Title
D-Xylose:NADP oxidoreductase of arterial vessels and eye lens: a new enzyme and a final link in ATP-independent cycling of reducing eqivalents in aldose-polyol-ketose interconversion.
Journal
Hoppe-Seyler's Z Physiol Chem 358:1300-1301 (1977)
Reference
2
Authors
Wissler JH.
Title
Direct spectrophotometric and specific quantitative determination of free and bound D-xylose by analytical application of a new enzyme, D-xylose:NADP-oxidoreductase.
Journal
Fresenius' Z Anal Chem 290:179-180 (1978)
Other DBs
ExPASy - ENZYME nomenclature database: 1.1.1.179