EC                Enzyme                                 

D-xylose 1-dehydrogenase (NADP+, D-xylono-1,5-lactone-forming);
D-xylose (nicotinamide adenine dinucleotide phosphate) dehydrogenase (ambiguous);
D-xylose-NADP dehydrogenase (ambiguous);
D-xylose:NADP+ oxidoreductase (ambiguous);
D-xylose 1-dehydrogenase (NADP) (ambiguous)
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
D-xylose:NADP+ 1-oxidoreductase (D-xylono-1,5-lactone-forming)
D-xylose + NADP+ = D-xylono-1,5-lactone + NADPH + H+ [RN:R01430]
D-xylose [CPD:C00181];
NADP+ [CPD:C00006]
D-xylono-1,5-lactone [CPD:C02266];
NADPH [CPD:C00005];
H+ [CPD:C00080]
The enzyme, characterized from pig arterial vessels and eye lens, also acts, more slowly, on L-arabinose and D-ribose. cf. EC, D-xylose 1-dehydrogenase (NADP+, D-xylono-1,4-lactone-forming).
EC created 1982, modified 2020
ec00040  Pentose and glucuronate interconversions
ec01100  Metabolic pathways
K00078  dihydrodiol dehydrogenase / D-xylose 1-dehydrogenase (NADP)
K14273  D-xylose 1-dehydrogenase (NADP+, D-xylono-1,5-lactone-forming)
HSA: 27294(DHDH)
PTR: 456194(DHDH)
PPS: 100991467(DHDH)
GGO: 101152398(DHDH)
PON: 100174691(DHDH)
NLE: 100591778(DHDH)
MCC: 718930(DHDH)
MCF: 102133381(DHDH)
CSAB: 103235003(DHDH)
CATY: 105595264(DHDH)
RRO: 104666542(DHDH)
RBB: 108523635(DHDH)
TFN: 117091536(DHDH)
CJC: 100390604(DHDH)
SBQ: 101049549(DHDH)
MMUR: 105865597(DHDH)
MMU: 71755(Dhdh)
MCAL: 110298665(Dhdh)
MPAH: 110337709(Dhdh)
RNO: 691002(Dhdh)
MCOC: 116102207(Dhdh)
MUN: 110540624(Dhdh)
CGE: 100753544(Dhdh)
PLEU: 114684644(Dhdh)
NGI: 103743638(Dhdh)
HGL: 101713222(Dhdh)
CPOC: 100731362(Dhdh)
CCAN: 109682683(Dhdh)
OCU: 100008610(DHDH)
OPI: 101528513(DHDH)
TUP: 102470508(DHDH)
CFA: 403786(DHDH)
VVP: 112931391(DHDH)
VLG: 121475970(DHDH)
AML: 100477136(DHDH)
UMR: 103657108(DHDH)
UAH: 113243321(DHDH)
ORO: 101371357(DHDH)
ELK: 111160798
MPUF: 101686519(DHDH)
EJU: 114199626(DHDH)
MLX: 117998244(DHDH)
FCA: 101101272(DHDH)
PYU: 121018750(DHDH)
PBG: 122494845(DHDH)
PTG: 102948867(DHDH)
PPAD: 109253091(DHDH)
AJU: 106988698(DHDH)
HHV: 120240202(DHDH)
BTA: 617564(DHDH)
BOM: 102280401(DHDH)
BIU: 109572213(DHDH)
BBUB: 102399742(DHDH)
CHX: 102188075(DHDH)
OAS: 101103175(DHDH)
ODA: 120872168(DHDH)
CCAD: 122421034(DHDH)
SSC: 397337(DHDH)
CFR: 102512639(DHDH)
CBAI: 105062610(DHDH)
CDK: 105102891(DHDH)
BACU: 103008204(DHDH)
ECB: 100051521(DHDH)
EPZ: 103553311(DHDH)
EAI: 106838267(DHDH)
MYB: 102262437(DHDH)
MYD: 102770117(DHDH)
MMYO: 118655427(DHDH)
MLF: 102443300(DHDH)
MNA: 107531900(DHDH)
PKL: 118712170(DHDH)
HAI: 109391066(DHDH)
DRO: 112310193(DHDH)
AJM: 119036829(DHDH)
PDIC: 114511061(DHDH)
MMF: 118639275(DHDH)
RFQ: 117034547(DHDH)
PALE: 102885391(DHDH)
PGIG: 120606955(DHDH)
RAY: 107498830(DHDH)
MJV: 108400314(DHDH)
TOD: 119249543(DHDH)
LAV: 100660549(DHDH)
TMU: 101355202
MDO: 100030403(DHDH)
GAS: 123242890(DHDH)
SHR: 111720213(DHDH)
PCW: 110220115(DHDH)
GGA: 777348(DHDH)
PCOC: 116240033(DHDH)
MGP: 104916162(DHDH)
CJO: 107325868(DHDH)
NMEL: 110390997(DHDH)
TGU: 115491770(DHDH)
LSR: 110481421(DHDH)
OTC: 121332636
PHI: 102104923(DHDH)
PMAJ: 107199051(DHDH)
ASN: 102376323(DHDH)
AMJ: 102574630(DHDH)
CPOO: 109320820(DHDH)
PSS: 102447655(DHDH)
CMY: 102931206(DHDH)
TST: 117888429(DHDH)
CABI: 116840048 116840080(DHDH)
PMUR: 107282543(DHDH)
TSR: 106538690(DHDH)
PGUT: 117669108(DHDH)
XLA: 108697264 444539(dhdh-like.1.L)
XTR: 100145807(dhdh) 448579(dhdh)
DRE: 406433(dhdh.1) 449558(dhdh.2)
SGH: 107553352 107595342(dhdh)
CCAR: 109063738(dhdh) 109075356
IPU: 100528487(dhdh)
PHYP: 113526400(dhdh)
EEE: 113576071
CGOB: 115025328
ELY: 117251231(dhdh.2) 117257557
PLEP: 121944994(dhdh.2) 121945624(dhdh.1) 121949449
SLUC: 116037533(dhdh.2)
ECRA: 117942893(dhdh.2)
PFLV: 114557526
GAT: 120831814(dhdh.2) 120834169
PPUG: 119226428(dhdh.2)
MSAM: 119889802(dhdh.2)
MZE: 101466663
OAU: 116325505 116325587(dhdh.2)
NFU: 107381267(dhdh) 107381268
HHIP: 117757207 117759290(dhdh.2)
XGL: 120794833(dhdh.1) 120801532
MALB: 109955837(dhdh)
SFM: 108930140
PKI: 111847990(dhdh)
LOC: 102692599(dhdh)
PSPA: 121294381
LCM: 102353287(DHDH)
CMK: 103189533
RTP: 109916392(dhdh)
BFO: 118407083
CIN: 100186038
DME: Dmel_CG13280(CG13280) Dmel_CG3597(CG3597) Dmel_CG3609(CG3609)
DSI: Dsimw501_GD11964(Dsim_GD11964) Dsimw501_GD22839(Dsim_GD22839) Dsimw501_GD22840(Dsim_GD22840)
MDE: 101900891
SCAC: 106086127
LCQ: 111676409
AME: 412231
ACER: 107997386
BIM: 100740559
BBIF: 117213213
BVK: 117239503
BVAN: 117162323
BTER: 100649548
BPYO: 122572759
CCAL: 108630663
OBB: 114873113
MGEN: 117218725
NMEA: 116431184
CGIG: 122403662
SOC: 105208047
MPHA: 105835107
AEC: 105154186
ACEP: 105622679
VEM: 105560923
HST: 105186645
DQU: 106741522
FEX: 115237753
LHU: 105671479
PGC: 109857477
OBO: 105284215
PCF: 106785709
PFUC: 122519681
VPS: 122630470
NVI: 100117805
TPRE: 106654210
MDL: 103578346
CGLO: 123267783
FAS: 105266916
DAM: 107036954
AGIF: 122854301
CCIN: 107264585
NVL: 108560837
OTU: 111428478
RMD: 113548345
ZNE: 110838823
CSEC: 111873256
HAME: 121862129
HAZT: 108682626
EAF: 111709298
VDE: 111250781
VJA: 111268866
CSCU: 111640181
SDM: 118197191
CRG: 105323672
MYI: 110455909
PMAX: 117339534
NVE: 5505671
EPA: 110244148
ATEN: 116289093
ADF: 107341873
AMIL: 114975326
PDAM: 113683557
SPIS: 111325722
DGT: 114517734
PTE: PTT_14440
CNE: CNE04820
SMIN: v1.2.018378.t1(symbB.v1.2.018378.t1)
SPAR: SPRG_05860
MCA: MCA0041
METL: U737_20635
MMAI: sS8_4175
MISZ: MishRS11D_44800(socC)
MEJ: Q7A_2650
MEC: Q7C_1095
AHA: AHA_2098
ASA: ASA_2199
AMED: B224_2088
AEL: NCTC12917_01967(afr)
SALN: SALB1_3671
MFA: Mfla_1214
MMB: Mmol_1981
MEH: M301_2404
MEP: MPQ_0833(mviM)
MBAC: BN1209_1717(mviM)
MPAU: ZMTM_17080
BHA: BH3843
BCL: ABC2696
BKW: BkAM31D_16055(afr_2)
GKA: GK1878
GTN: GTNG_1790
ANM: GFC28_950
AAMY: GFC30_2161
ANL: GFC29_676
AXL: AXY_19480
PSYO: PB01_01580
BLEN: NCTC4824_03507(afr_8)
BSE: Bsel_2006
PPO: PPM_2025(M1_2306)
PPOY: RE92_01815
PMW: B2K_16730
PSAB: PSAB_22875
PRI: PRIO_6414
PSWU: SY83_04270
PBK: Back11_02790(socC)
AAC: Aaci_2618
AAD: TC41_2914
SIV: SSIL_3749
MHEV: MHEL_37770
STRM: M444_32545
SCYG: S1361_01430(gfo1)
MOO: BWL13_00475(afr_3)
SESP: BN6_32320
CAU: Caur_3022
CAG: Cagg_3563
ATM: ANT_01810
TRA: Trad_0849
ROL: CA51_12430(afr_3)
LCRE: Pla8534_20100(afr_4)
RLC: K227x_13220(afr_3)
PLS: VT03_17280(gfo_3)
PLH: VT85_08640(afr_3)
GPN: Pan110_35270(gfo_7)
MRI: Mal4_21560(afr_6)
IPA: Isop_1854
SACI: Sinac_3314
PBOR: BSF38_00094(afr_1)
AGV: OJF2_68930(afr_2)
PCOR: KS4_29150(afr_4)
ABAC: LuPra_04720(afr_6)
HHB: Hhub_2517
HMA: rrnAC2929(gfo1)
HHI: HAH_0191(gfo1)
HUT: Huta_0347
HTI: HTIA_0527
HMU: Hmuk_0258
HALL: LC1Hm_2790(xdh2)
HDS: HSR122_2553(mviM6)
HVO: HVO_B0029
HLA: Hlac_2419
HTU: Htur_0178
SALI: L593_09740
 » show all
Wissler, J.H.
D-Xylose:NADP oxidoreductase of arterial vessels and eye lens: a new enzyme and a final link in ATP-independent cycling of reducing eqivalents in aldose-polyol-ketose interconversion.
Hoppe-Seyler's Z Physiol Chem 358:1300-1301 (1977)
Wissler, J.H.
Direct spectrophotometric and specific quantitative determination of free and bound D-xylose by analytical application of a new enzyme, D-xylose:NADP-oxidoreductase.
Fresenius' Z Anal Chem 290:179-180 (1978)
Other DBs
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IUBMB Enzyme Nomenclature:
ExPASy - ENZYME nomenclature database:
BRENDA, the Enzyme Database:
CAS: 83534-37-6

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