Entry
Name
geraniol dehydrogenase (NADP+)
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
geraniol:NADP+ oxidoreductase
Reaction(IUBMB)
geraniol + NADP+ = geranial + NADPH + H+ [RN:
R03581 ]
Reaction(KEGG)
Substrate
Product
Comment
Also acts, more slowly on farnesol but not on nerol. The enzyme produces a mixture known as citral, which includes geranial and neral. It is still not known whether neral is produced directly by the enzyme, or by isomerization of geranial.
History
EC 1.1.1.183 created 1983
Pathway
ec00907 Pinene, camphor and geraniol degradation
ec01120 Microbial metabolism in diverse environments
Orthology
K12957 alcohol/geraniol dehydrogenase (NADP+)
Genes
ECOO : ECRM13514_5530(yjgB)
ECOH : ECRM13516_5083(yjgB)
EDJ : ECDH1ME8569_4123(yjgB)
ECOI : ECOPMV1_04737(adhC)
REE : electrica_04519(adhC2)
RTG : NCTC13098_06562(adhC2_2)
CLAP : NCTC11466_00426(adhC2)
KIE : NCTC12125_03163(adhC2_1)
PLF : PANA5342_p10305(yjgB)
PVA : Pvag_pPag10027(yjgB)
PANZ : NR302_23490 NR302_23495
TPTY : NCTC11468_00471(adhC2)
PAET : NCTC13378_00701(adhC2)
PKQ : ACEJ41_04285 ACEJ41_04340
AVZ : HWI77_00240 HWI77_17310
ATV : ABEF79_15825 ABEF79_16570
SALH : HMF8227_00173(yjgB)
LLG : 44548918_02176(yahK_1)
NANI : NCTC12227_00525(adhA_2)
FIL : BN1229_v1_1228(yjgB)
FIY : BN1229_v1_1226(yjgB)
SFLA : SPHFLASMR4Y_03374(ahr)
SMAM : Mal15_29790(ahr_1) Mal15_58630(ahr_2)
GOG : C1280_02770 C1280_12775
EPL : P4G45_10000 P4G45_14245
MKU : I2456_07315 I2456_16485
SYY : SYNGTS_3134(slr1192)
SYT : SYNGTI_3133(slr1192)
SYS : SYNPCCN_3132(slr1192)
SYQ : SYNPCCP_3132(slr1192)
» show all
Taxonomy
Reference
1
Authors
Potty VH, Bruemmer JH.
Title
Oxidation of geraniol by an enzyme system from orange.
Journal
Phytochemistry 9:1001-1007 (1970)
Reference
Authors
Sekiwa-Iijima Y, Aizawa Y, Kubota K
Title
Geraniol dehydrogenase activity related to aroma formation in ginger (Zingiber officinale Roscoe).
Journal
Reference
Authors
Saito Y, Ito S, Koltunow AM, Sakai H
Title
Crystallization and preliminary X-ray analysis of geraniol dehydrogenase from Backhousia citriodora (lemon myrtle).
Journal
Other DBs
ExPASy - ENZYME nomenclature database: 1.1.1.183
UM-BBD (Biocatalysis/Biodegradation Database): 1.1.1.183