KEGG   ENZYME: 1.1.1.183
Entry
EC 1.1.1.183                Enzyme                                 
Name
geraniol dehydrogenase (NADP+)
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
geraniol:NADP+ oxidoreductase
Reaction(IUBMB)
geraniol + NADP+ = geranial + NADPH + H+ [RN:R03581]
Reaction(KEGG)
R03581;
(other) R08083 R08084 R08085
Substrate
geraniol [CPD:C01500];
NADP+ [CPD:C00006]
Product
geranial [CPD:C01499];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
Also acts, more slowly on farnesol but not on nerol. The enzyme produces a mixture known as citral, which includes geranial and neral. It is still not known whether neral is produced directly by the enzyme, or by isomerization of geranial.
History
EC 1.1.1.183 created 1983
Pathway
ec00281  Geraniol degradation
ec01110  Biosynthesis of secondary metabolites
Orthology
K12957  alcohol/geraniol dehydrogenase (NADP+)
Genes
ECOb4269(ahr)
ECJJW5761(yjgB)
ECDECDH10B_4462(yjgB)
EBWBWG_3975(yjgB)
ECOKECMDS42_3708(yjgB)
ECEZ5876(yjgB)
ECSECs_5241(ahr)
ECFECH74115_5786
ETWECSP_5365(yjgB)
ELXCDCO157_4925
EOIECO111_5148(yjgB)
EOJECO26_5434(yjgB)
EOHECO103_5060(yjgB)
ECOOECRM13514_5530(yjgB)
ECOHECRM13516_5083(yjgB)
ESLO3K_22295
ESOO3O_03100
ESMO3M_22190
ECKEC55989_4827(yjgB)
ECGE2348C_4588(yjgB)
EOKG2583_5094(yjgB)
ELRECO55CA74_24430
ELHETEC_4610
ECWEcE24377A_4837
EUNUMNK88_5210
ECPECP_4519
ENAECNA114_4488(yjgB)
ECOSEC958_4759(yjgB)
ECVAPECO1_2125(yjgB)
ECOAAPECO78_02315
ECXEcHS_A4525
ECMEcSMS35_4750
ECRECIAI1_4495(yjgB)
ECQECED1_5123(yjgB)
EUMECUMN_4801(yjgB)
ECTECIAI39_4742(yjgB)
EOCCE10_5015(yjgB)
EBRECB_04135(yjgB)
EBLECD_04135(ahr)
EBEB21_04099(yjgB)
EBDECBD_3767
ECIUTI89_C4876(yjgB)
EIHECOK1_4786
ECZECS88_4851(yjgB)
ECCc5370(yjgB)
ELOEC042_4739
ELNNRG857_21710
ESEECSF_4157
ECLEcolC_3748
EKOEKO11_4044
EKFKO11_22990(yjgB)
EABECABU_c48340(yjgB)
EDHEcDH1_3728
EDJECDH1ME8569_4123(yjgB)
ELUUM146_21605
ELWECW_m4629(yjgB)
ELLWFL_22545(yjgB)
ELCi14_4873(yjgB)
ELDi02_4873(yjgB)
ELPP12B_c4376(yjgB)
ELFLF82_3470(yjgB)
ECOLLY180_22410
ECOIECOPMV1_04737(adhC)
ECOJP423_23735
EFEEFER_3111(yjgB)
EALEAKF1_ch1562
STMSTM4486(yjgB)
SEOSTM14_5383(yjgB)
SEVSTMMW_44321
SEYSL1344_4416(yjgB)
SEMSTMDT12_C46140
SEJSTMUK_4472(yjgB)
SEBSTM474_4684(yjgB)
SEFUMN798_4856
SETUSTU288_22500
SETCCFSAN001921_18000
SENRSTMDT2_43321
SENDDT104_44761
SENICY43_23360
SEENSE451236_05450
SPTSPA4286(yjgB)
SEKSSPA3983
SPQSPAB_05644
SEISPC_4618(yjgB)
SECSCH_4342(yjgB)
SEHSeHA_C4890
SHBSU5_0534
SENHCFSAN002069_09765
SEEHSEEH1578_08495
SEESNSL254_A4834
SENNSN31241_8560
SEWSeSA_A4741
SEASeAg_B4771
SENSQ786_22100
SEDSeD_A4871
SEGSG4310(yjgB)
SELSPUL_4462(yjgB)
SEGASPUCDC_4448(yjgB)
SETSEN4239(yjgB)
SENAAU38_21860
SENOAU37_21875
SENVAU39_21895
SENQAU40_24440
SENLIY59_22430
SENJCFSAN001992_11540
SEECCFSAN002050_05840
SEEBSEEB0189_019960
SEEPI137_21340
SENBBN855_45630
SENEIA1_21860
SENCSEET0819_06295
SESSARI_03157
SBGSBG_3905(yjgB)
SBZA464_4476
SBVN643_19765
SALZEOS98_19795
SFLSF4225(yjgB)
SFXS4486(yjgB)
SFVSFV_4229(yjgB)
SFESFxv_4607
SFNSFy_6065
SFSSFyv_6135
SFTNCTC1_04593(yjgB)
SSNSSON_4454(yjgB)
SBOSBO_4176(yjgB)
SBCSbBS512_E4816
SDYSDY_4288(yjgB)
SHQA0259_02990
ENCECL_04598
ENLA3UG_20375
ECLGEC036_39770
ECLEECNIH2_20880
ECLNECNIH4_02830
ECLIECNIH5_19490
ECLXLI66_20145
ECLYLI62_22125
ECLZLI64_19245
ECLOENC_34550
EHMAB284_05250
EXFBFV63_19625
ECLAECNIH3_19590
ECLCECR091_19515
EAUDI57_20885
EKBBFV64_20985
ENOECENHK_19800
EECEcWSU1_04022(yjgB)
ELGBH714_19705
ECANCWI88_02355
ERNBFV67_19640
ECLSLI67_021560
ECHGFY206_21955
ESHC1N69_20510
ENTEnt638_3652
EASEntas_3903
ENRH650_18060
ENXNI40_019875
ENFAKI40_4427
LNICWR52_15050
EBGFAI37_09200
ENDA4308_04475
ENZG0034_20420
ENSHWQ15_05465
ENKLOC22_08190
EHUD5067_0002555
EMORL6Y89_19715
ENBELK40_20220
ESAESA_03438 ESA_03457
CSKES15_3418(yjgB)
CSZCSSP291_16060
CSJCSK29544_00388
CCONAFK62_02710
CDMAFK67_02695
CSIP262_05066
CMJAFK66_017110
CUIAFK65_02625
CMWAFK63_15880
CTUCTU_05090(yjgB)
KPNKPN_04683(yjgB)
KPUKP1_0570(yjgB)
KPMKPHS_05370
KPPA79E_4513
KPHKPNIH24_02770
KPZKPNIH27_02690
KPVKPNIH29_02850
KPWKPNIH30_02910
KPYKPNIH31_05195
KPGKPNIH32_02915
KPCKPNIH10_02755
KPQKPR0928_02765
KPTVK055_2769
KPOKPN2242_01510
KPRKPR_0660(yjgB)
KPID364_23850
KPAKPNJ1_04923
KPSKPNJ2_04872
KPXPMK1_02151(adhA)
KPBFH42_19830
KPNEKU54_023835
KPNULI86_23675
KPNKBN49_4754(yjgB)
KVAKvar_4571
KPEKPK_4982
KPKA593_13465
KVDKR75_10920
KVQSP68_17505
KOXKOX_09430
KOEA225_0562
KOYJ415_00315
KOMHR38_08150
KMIVW41_20790
KOKKONIH1_03075
KOCAB185_33140
KQUAVR78_07315
EAEEAE_09865
EARCCG32062
KQVB8P98_24635
KLLBJF97_03825
KLWDA718_25630
KARLGL98_22245
KGRJJJ10_24745
RORRORB6_16095
RONTE10_04930
RPLNB1209_24105
RAODSD31_22905
RTGNCTC13098_06562(adhC2_2)
REEelectrica_04519(adhC2)
CROROD_33301
CKOCKO_03534
CFDCFNIH1_09120
CBRAA6J81_13970
CWECO701_18990
CYOCD187_21120
CPOTFOB25_08450
CFQC2U38_02575
CSEDJY391_19385
CAMAF384_16970
CAFAL524_06395
CIFAL515_04280
CFARCI104_21935
CIRC2U53_13235
CIEAN232_00920
CPARCUC49_22275
CTELGBC03_07900
CITZE4Z61_14060
CARSE1B03_03980
EBTEBL_c34810(yjgB)
CNTJT31_15175
CEMLH23_02525
CENLH86_02475
CLAPNCTC11466_00426(adhC2)
PGELG71_00670
ESCEntcl_3879
KLEAO703_02525
KSAC813_12385
KORAWR26_22340
KRDA3780_01380
KCOBWI95_02900
KOTEH164_19675
KPSEIP581_02665
KIENCTC12125_03163(adhC2_1)
KASKATP_40060
LAXAPT61_02570
LEIC2U54_02150
LEHC3F35_14455
LEEDVA44_02575
LERGNG29_20430
LEAGNG26_19615
LPNUKQ929_01990
LAZA8A57_18980
LEFLJPFL01_3756
METYMRY16398_49730
YREHEC60_20360
SGOEA8O29_019960
KINAB182_22320
PDZHHA33_25025
IZHFEM41_08430
PSGCG163CM_30200(ahr)
EBFD782_3967
EBCC2U52_04320
EBUCUC76_12625
PSTSE05_27690
SFWWN53_04090
SFOZ042_08090
RAHRahaq_0643
RACEJHW33_19820
RAQRahaq2_0663
RAAQ7S_02940
ROXBV494_20080
RVCJ9880_10760
ECAECA3198
PATREV46_15845
PATOGZ59_32100
PCTPC1_2982
PCCPCC21_030220
PCVBCS7_15155
PWAPecwa_1292
PPARA8F97_12410
PECW5S_1199
PWSA7983_01800
PPOABJK05_10065
PBRAB5S52_06725
PPUJE2566_15410
PARII2D83_06710
PAQUDMB82_0006340
PVZOA04_32470(ahr)
PPAVLOZ86_14950
PQUIG609_005800
EAMEAMY_3520(yjgB)
EAYEAM_3313
ETAETA_33100
EPYEpC_35100
EPREPYR_03771(yjgB)
EBIEbC_21010
ERJEJP617_09900
EGEEM595_0200(yjgB)
EPECI789_19770
ERWIGN242_01070
ERPLJN55_01340
PAMPANA_4164(yjgB)
PLFPANA5342_p10305(yjgB)
PAJPAJ_p0120(yjgB)
PAQPAGR_p231
PVAPvag_pPag10027(yjgB)
PAGGAL522_02670
PAOPat9b_5232
PANTPSNIH1_p01450
PANPPSNIH2_09660
PAGCBEE12_23075
PSTWDSJ_25950
PALHB1H58_18890
PANSFCN45_21310
PEYEE896_21720
PDISD8B20_19355
PERLAC65_17670
PGZC2E15_08990
PCDC2E16_08980
MINTC7M51_01034(ahr)
MTHIC7M52_01782(ahr)
TCIA7K98_02170
TPTYNCTC11468_00471(adhC2)
HAVAT03_17035
OPODSM2777_08190
FCLA4G17_07900
PAETNCTC13378_00701(adhC2)
PSUWWQ53_09835
PDDMNQ95_08360
LAREHIV01_014660
RHDR2APBS1_0784
RTHLRK53_05455
DJICH75_01685
DJAHY57_19430
DTLH8F01_05750
DTADYST_04238
XBAC7S18_14385
PMYPmen_3746
PMKMDS_4063
PPSEBN5_0783
PALCA0T30_05300
PFOPfl01_2347
PENPSEEN2684
PPUUPputUW4_03046
PKEDLD99_12510
PALLUYA_19590
PUMHGP31_17840
PGYAWU82_15370
PSEJHNQ25_05840
PKHJLK41_20850
PTYJWV26_05835
PMAOPMYSY11_3504(ahr)
PCAMHNE05_14735
PAZEKSS91_16830
PWZJ7655_19190
PWYHU734_013545
PCRPcryo_2398
PSOPSYCG_12955
PALIA3K91_0774
PSYPE5677_09510
ACBA1S_3436
ABMABSDF3625
ABYABAYE0043
ABCACICU_03634
ABNAB57_3891
ABBABBFA_00042(ahr)
ABXABK1_3688
ABZABZJ_03825
ABRABTJ_00046
ABDABTW07_3840
ABHM3Q_178 M3Q_404
ABADABD1_33390
ABJBJAB07104_03735
ABABBJAB0715_03822
ABAJBJAB0868_03683
ABAZP795_0210
ABKLX00_18530
ABAUIX87_14220
ABAAIX88_01975
ABWBL01_06735
ABALABLAC_00430
ACCBDGL_002906(yjgB)
ANORR32_00225
ALCOTEC02_00235
ACALBUM88_19365
ASEII8T81_00230
ACDAOLE_00200
ACIACIAD3612
ATTAMQ28_07825
AJORZ95_00280
ACWA0J50_00130
AHLAHTJS_00245
AJNBVL33_01660
ASOLBEN76_12920
ASJAsACE_CH02826(adhC)
AIDCTZ23_00255
ADVDJ533_02745
ARJDOM24_14140
AWUBEN71_00995
ACUMC9E88_003975
AGUAS4_00600(alrA)
AUGURS_1050
ALWFOB21_09640
ADSFPL17_14620
ABERBSR55_20885
ATNFM020_16205
ACHICDG60_17740
AWGGFH30_12975
ATGJ4G44_02260
AVBRYU24_00560(yjgB)
ABOUACBO_00510(yjgB)
AGYLFPL18_07250
ACIUA3K93_12425
AVZHWI77_00240 HWI77_17310
MBAHHYN46_11725
PATPatl_2391
PSEOOM33_19970
PSPOPSPO_b0496(yjgB)
PSYMJ1N51_08400
AMCMADE_1007575
AMHI633_07735
AMAAamad1_07700
AMALI607_06915
AMAEI876_07210
AMAOI634_07325
AMADI636_07780
AMAII635_07690
AMAGI533_07235
AMACMASE_06850
AMBAMBAS45_07185
AMGAMEC673_06910
AMKAMBLS11_06865
ALTambt_11195
ASPAOR13_2054
ASQAVL57_09000
AAWAVL56_07890
ALEAV939_08015
ALZAV940_07845
SALKFBQ74_02735
GAGGlaag_1975
SALHHMF8227_00173(yjgB)
SDESde_3956
GILNHM04_08855
MICCAUP74_00824(ahr)
MIIBTJ40_09270
MICTFIU95_07485(ahr)
MHYDGTQ55_00470
MCELLPW13_16290
MICZGL2_31350(yjgB)
LHALHA_2572(yjgB)
LLG44548918_02176(yahK_1)
TMCLMI_2728(yjgB)
MPINLGT42_010985
HNAHneap_1375
HAZA9404_00985
TOLTOL_3305
TORR615_15570
OAIOLEAN_C03110
BSANCHH28_07715
BMARHF888_13815
VCWGJQ55_01420
BACZKFF03_13950
ENWMJO57_22055
FCEJN531_007980
ACIIC4901_07770
ATYA9R16_007175
NANINCTC12227_00525(adhA_2)
NAWLVJ86_03705
LIMNHKT17_09890
RSBRS694_15405
RHOAHZ993_21810
AONDEH84_10405
NITNAL212_1252
NIINit79A3_1181
NCOAAW31_08575
NURATY38_10105
NMUNmul_A1400
NLCEBAPG3_007870
SEMEMIZ01_1789
SULFCAP31_04095
SPLBSFPGR_30260(yjgB)
ATWC0099_14640
DEUDBW_0736
AVMJQX13_17280
MRMA7982_00710
BIDBind_1144
MSLMsil_1987
HDNHden_2510
FILBN1229_v1_1228(yjgB)
FIYBN1229_v1_1226(yjgB)
GAKX907_2278
HYTHXX25_08645
HBAHbal_1174
SFLASPHFLASMR4Y_03374(ahr)
SPHYCHN51_11350
DEXHWD60_19735
DVNHQ394_13755
MKUI2456_07315 I2456_16485
MTYMTOK_07050(yjgB)
SVLStrvi_8773
SRCM271_27765
SMALSMALA_3483
SSOII1A49_21180
SAUOBV401_20880
KFLKfla_3954
APRECNX65_16865
AMIAmir_3359
ACTNL083_0691
SYNslr1192
SYZMYO_131700
SYYSYNGTS_3134(slr1192)
SYTSYNGTI_3133(slr1192)
SYSSYNPCCN_3132(slr1192)
SYQSYNPCCP_3132(slr1192)
SYJD082_11380
SYOC7I86_16455
SYXSynWH7803_0815
SYNESyn6312_2029
SYNPSyn7502_02611
SYNCCB0101_03050
SYNYBM449_13200
DSLDacsa_2985
CGCCyagr_1734
AMRAM1_4818
PSEUPse7367_0781
GEEGM3708_618
MARMAE_49470
MPKVL20_2787
MIQB5D77_10410
MVZmyaer102_22710
CANCyan10605_3131
CYPPCC8801_1449
CYHCyan8802_1475
CYCPCC7424_5216
CYJCyan7822_3475
ARPNIES39_L00820
OXYHCG48_18485
LFSHFV01_03030
NOSNos7107_4857
NONNOS3756_12740
RIVRiv7116_2823
CTHEChro_0641
PLPPle7327_0886
RUFIK0V07_15680
ROOG5S37_08310
LUOHHL09_04240
RBARB11151(yjgB)
PSLPsta_0582
PIRVN12_06560(ahr)
RULUC8_00800(ahr)
RMLFF011L_22650(ahr)
MFFMFFC18_48760(ahr)
ROLCA51_01530(ahr)
AHELQ31a_19710(ahr)
LCREPla8534_14770(ahr)
AAGGETAA8_15360(ahr)
RLCK227x_06490(ahr)
LPAVPLANPX_4105
PNDPla175_24310(ahr)
PLMPlim_2975
PEHSpb1_37330(ahr)
PBSPlabr_4772
PLSVT03_15665(ahr)
GMRGmarT_07270(ahr)
GESVT84_00425(ahr)
GOGC1280_02770 C1280_12775
GMSSOIL9_73480
LRSPX52LOC_02726
FTJFTUN_2805
ULIETAA1_48770(ahr)
TSPHKIH39_23600
SACISinac_0585
AGVOJF2_07190(ahr)
PCORKS4_05060(ahr)
MCADPan265_02300(ahr)
HBSIPV69_21200
ACMAciX9_1430
GRWFTO74_10120
GRBGOB94_14790
ABASACPOL_1479
EDAGWR55_03800
SUSAcid_2579
CPICpin_2208
CHIHGWR21_26325
COYHF329_09070
CFILMYF79_31305
SGNSGRA_0746
MGKFSB76_02015
SRHOHH216_16975
CBALM667_15805
MLTVC82_719
AICJK629_02100
SZEAW14_10190
TMARMARIT_1822(yjgB)
MARFCJ739_3821
AQDD1816_05730
MUREQY75_05325
MESQC7H62_2232
ZSPMQE36_09160
TAANMY3_01370(ahr)
NFNNFRAN_2275(ahr)
 » show all
Reference
1
  Authors
Potty, V.H. and Bruemmer, J.H.
  Title
Oxidation of geraniol by an enzyme system from orange.
  Journal
Phytochemistry 9:1001-1007 (1970)
Reference
2  [PMID:11743782]
  Authors
Sekiwa-Iijima Y, Aizawa Y, Kubota K
  Title
Geraniol dehydrogenase activity related to aroma formation in ginger (Zingiber officinale Roscoe).
  Journal
J Agric Food Chem 49:5902-6 (2001)
DOI:10.1021/jf0102970
Reference
3  [PMID:21636906]
  Authors
Saito Y, Ito S, Koltunow AM, Sakai H
  Title
Crystallization and preliminary X-ray analysis of geraniol dehydrogenase from Backhousia citriodora (lemon myrtle).
  Journal
Acta Crystallogr Sect F Struct Biol Cryst Commun 67:665-7 (2011)
DOI:10.1107/S1744309111006920
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.183
IUBMB Enzyme Nomenclature: 1.1.1.183
ExPASy - ENZYME nomenclature database: 1.1.1.183
UM-BBD (Biocatalysis/Biodegradation Database): 1.1.1.183
BRENDA, the Enzyme Database: 1.1.1.183
CAS: 56802-96-1

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