KEGG   ENZYME: 1.1.1.183
Entry
EC 1.1.1.183                Enzyme                                 

Name
geraniol dehydrogenase (NADP+)
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
geraniol:NADP+ oxidoreductase
Reaction(IUBMB)
geraniol + NADP+ = geranial + NADPH + H+ [RN:R03581]
Reaction(KEGG)
R03581;
(other) R08083 R08084 R08085
Substrate
geraniol [CPD:C01500];
NADP+ [CPD:C00006]
Product
geranial [CPD:C01499];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
Also acts, more slowly on farnesol but not on nerol. The enzyme produces a mixture known as citral, which includes geranial and neral. It is still not known whether neral is produced directly by the enzyme, or by isomerization of geranial.
History
EC 1.1.1.183 created 1983
Pathway
ec00281  Geraniol degradation
ec01110  Biosynthesis of secondary metabolites
Orthology
K12957  alcohol/geraniol dehydrogenase (NADP+)
Genes
ZJU: 107434484
ECO: b4269(ahr)
ECJ: JW5761(yjgB)
ECD: ECDH10B_4462(yjgB)
EBW: BWG_3975(yjgB)
ECOK: ECMDS42_3708(yjgB)
ECE: Z5876(yjgB)
ECS: ECs5241
ECF: ECH74115_5786
ETW: ECSP_5365(yjgB)
EOI: ECO111_5148(yjgB)
EOJ: ECO26_5434(yjgB)
EOH: ECO103_5060(yjgB)
ECOO: ECRM13514_5530(yjgB)
ECOH: ECRM13516_5083(yjgB)
ESL: O3K_22295
ESO: O3O_03100
ESM: O3M_22190
ECK: EC55989_4827(yjgB)
ECG: E2348C_4588(yjgB)
EOK: G2583_5094(yjgB)
ELH: ETEC_4610
ECP: ECP_4519
ENA: ECNA114_4488(yjgB)
ECOS: EC958_4759(yjgB)
ECV: APECO1_2125(yjgB)
ECR: ECIAI1_4495(yjgB)
ECQ: ECED1_5123(yjgB)
EUM: ECUMN_4801(yjgB)
ECT: ECIAI39_4742(yjgB)
EOC: CE10_5015(yjgB)
EBR: ECB_04135(yjgB)
EBL: ECD_04135(ahr)
EBE: B21_04099(yjgB)
EBD: ECBD_3767
ECI: UTI89_C4876(yjgB)
ECZ: ECS88_4851(yjgB)
ECC: c5370(yjgB)
ESE: ECSF_4157
EKF: KO11_22990(yjgB)
EAB: ECABU_c48340(yjgB)
EDJ: ECDH1ME8569_4123(yjgB)
ELW: ECW_m4629(yjgB)
ELL: WFL_22545(yjgB)
ELC: i14_4873(yjgB)
ELD: i02_4873(yjgB)
ELP: P12B_c4376(yjgB)
ELF: LF82_3470(yjgB)
ECOI: ECOPMV1_04737(adhC)
ECOJ: P423_23735
EFE: EFER_3111(yjgB)
STM: STM4486(yjgB)
SEO: STM14_5383(yjgB)
SEY: SL1344_4416(yjgB)
SEJ: STMUK_4472(yjgB)
SEB: STM474_4684(yjgB)
SENI: CY43_23360
SPT: SPA4286(yjgB)
SEK: SSPA3983
SEI: SPC_4618(yjgB)
SEC: SCH_4342(yjgB)
SHB: SU5_0534
SENS: Q786_22100
SED: SeD_A4871
SEG: SG4310(yjgB)
SEL: SPUL_4462(yjgB)
SEGA: SPUCDC_4448(yjgB)
SET: SEN4239(yjgB)
SENA: AU38_21860
SENO: AU37_21875
SENV: AU39_21895
SENQ: AU40_24440
SENL: IY59_22430
SEEP: I137_21340
SENE: IA1_21860
SBG: SBG_3905(yjgB)
SBZ: A464_4476
SFL: SF4225(yjgB)
SFX: S4486(yjgB)
SFV: SFV_4229(yjgB)
SFE: SFxv_4607
SFN: SFy_6065
SFS: SFyv_6135
SFT: NCTC1_04593(yjgB)
SSN: SSON_4454(yjgB)
SBO: SBO_4176(yjgB)
SDY: SDY_4288(yjgB)
ENC: ECL_04598
ECLO: ENC_34550
ECLX: LI66_20145
ECLY: LI62_22125
ECLZ: LI64_19245
EEC: EcWSU1_04022(yjgB)
CSK: ES15_3418(yjgB)
CTU: CTU_05090(yjgB)
KPN: KPN_04683(yjgB)
KPU: KP1_0570(yjgB)
KPP: A79E_4513
KPR: KPR_0660(yjgB)
KPX: PMK1_02151(adhA)
KPNU: LI86_23675
KPNK: BN49_4754(yjgB)
KVA: Kvar_4571
KPE: KPK_4982
KOX: KOX_09430
KOE: A225_0562
EAE: EAE_09865
EAR: CCG32062
CRO: ROD_33301
CKO: CKO_03534
CAMA: F384_16970
EBT: EBL_c34810(yjgB)
RTG: NCTC13098_06562(adhC2_2)
REE: electrica_04519(adhC2)
CLAP: NCTC11466_00426(adhC2)
KIE: NCTC12125_03163(adhC2_1)
EBF: D782_3967
PSTS: E05_27690
RAA: Q7S_02940
ECA: ECA3198
PATR: EV46_15845
PATO: GZ59_32100
PCT: PC1_2982
PEC: W5S_1199
EAM: EAMY_3520(yjgB)
EAY: EAM_3313
ETA: ETA_33100
EPY: EpC_35100
EPR: EPYR_03771(yjgB)
EBI: EbC_21010
EGE: EM595_0200(yjgB)
PAM: PANA_4164(yjgB)
PLF: PANA5342_p10305(yjgB)
PAJ: PAJ_p0120(yjgB)
PAQ: PAGR_p231
PVA: Pvag_pPag10027(yjgB)
PSTW: DSJ_25950
MINT: C7M51_01034(ahr)
MTHI: C7M52_01782(ahr)
TPTY: NCTC11468_00471(adhC2)
PAET: NCTC13378_00701(adhC2)
PSUW: WQ53_09835
PMY: Pmen_3746
PMK: MDS_4063
PPSE: BN5_0783
PEN: PSEEN2684
PALI: A3K91_0774
ACB: A1S_3436
ABM: ABSDF3625
ABY: ABAYE0043
ABN: AB57_3891
ABB: ABBFA_00042(ahr)
ABX: ABK1_3688
ABAD: ABD1_33390
ABAZ: P795_0210
ABAU: IX87_14220
ABAA: IX88_01975
ACC: BDGL_002906(yjgB)
ACI: ACIAD3612
ASJ: AsACE_CH02826(adhC)
AGU: AS4_00600(alrA)
AUG: URS_1050
PAT: Patl_2391
PSEO: OM33_19970
PSPO: PSPO_b0496(yjgB)
AMAL: I607_06915
AMAE: I876_07210
AMAO: I634_07325
AMAD: I636_07780
AMAI: I635_07690
AMAG: I533_07235
AMAC: MASE_06850
SALH: HMF8227_00173(yjgB)
SDE: Sde_3956
MICC: AUP74_00824(ahr)
MICT: FIU95_07485(ahr)
LHA: LHA_2572(yjgB)
LLG: 44548918_02176(yahK_1)
TMC: LMI_2728(yjgB)
TOL: TOL_3305
SPLB: SFPGR_30260(yjgB)
DEU: DBW_0736
BID: Bind_1144
MSL: Msil_1987
HDN: Hden_2510
FIL: BN1229_v1_1228(yjgB)
FIY: BN1229_v1_1226(yjgB)
HBA: Hbal_1174
GAK: X907_2278
SFLA: SPHFLASMR4Y_03374(ahr)
SMAL: SMALA_3483
KFL: Kfla_3954
AMI: Amir_3359
ACTN: L083_0691
SYN: slr1192
SYY: SYNGTS_3134(slr1192)
SYT: SYNGTI_3133(slr1192)
SYS: SYNPCCN_3132(slr1192)
SYQ: SYNPCCP_3132(slr1192)
AMR: AM1_4818
MAR: MAE_49470
MPK: VL20_2787
CTHE: Chro_0641
RBA: RB11151(yjgB)
PSL: Psta_0582
PIR: VN12_06560(ahr)
RUL: UC8_00800(ahr)
MFF: MFFC18_48760(ahr)
PLM: Plim_2975
PEH: Spb1_37330(ahr)
PLS: VT03_15665(ahr)
GMR: GmarT_07270(ahr)
GES: VT84_00425(ahr)
SACI: Sinac_0585
AGV: OJF2_07190(ahr)
ABAS: ACPOL_1479
SUS: Acid_2579
CPI: Cpin_2208
SGN: SGRA_0746
CBAL: M667_15805
MLT: VC82_719
TMAR: MARIT_1822(yjgB)
MARF: CJ739_3821
MESQ: C7H62_2232
TAA: NMY3_01370(ahr)
NFN: NFRAN_2275(ahr)
 » show all
Reference
1
  Authors
Potty, V.H. and Bruemmer, J.H.
  Title
Oxidation of geraniol by an enzyme system from orange.
  Journal
Phytochemistry 9:1001-1007 (1970)
Reference
2  [PMID:11743782]
  Authors
Sekiwa-Iijima Y, Aizawa Y, Kubota K
  Title
Geraniol dehydrogenase activity related to aroma formation in ginger (Zingiber officinale Roscoe).
  Journal
J Agric Food Chem 49:5902-6 (2001)
DOI:10.1021/jf0102970
Reference
3  [PMID:21636906]
  Authors
Saito Y, Ito S, Koltunow AM, Sakai H
  Title
Crystallization and preliminary X-ray analysis of geraniol dehydrogenase from Backhousia citriodora (lemon myrtle).
  Journal
Acta Crystallogr Sect F Struct Biol Cryst Commun 67:665-7 (2011)
DOI:10.1107/S1744309111006920
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.183
IUBMB Enzyme Nomenclature: 1.1.1.183
ExPASy - ENZYME nomenclature database: 1.1.1.183
UM-BBD (Biocatalysis/Biodegradation Database): 1.1.1.183
BRENDA, the Enzyme Database: 1.1.1.183
CAS: 56802-96-1

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