Entry |
|
Name |
glucuronate reductase;
L-hexonate:NADP dehydrogenase;
TPN-L-gulonate dehydrogenase;
NADP-L-gulonate dehydrogenase;
D-glucuronate dehydrogenase;
D-glucuronate reductase;
L-glucuronate reductase (incorrect)
|
Class |
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
|
Sysname |
L-gulonate:NADP+ 6-oxidoreductase
|
Reaction(IUBMB) |
L-gulonate + NADP+ = D-glucuronate + NADPH + H+ [RN: R01481]
|
Reaction(KEGG) |
|
Substrate |
|
Product |
|
Comment |
Also reduces D-galacturonate. May be identical with EC 1.1.1.2 [alcohol dehydrogenase (NADP+)].
|
History |
EC 1.1.1.19 created 1961
|
Pathway |
ec00040 | Pentose and glucuronate interconversions |
ec00053 | Ascorbate and aldarate metabolism |
|
Reference |
|
Authors |
SIVAK A, HOFFMANN-OSTENHOF O. |
Title |
Enzymes of mesoinositol catabolism in the yeast Schwanniomyces accidentalis. |
Journal |
|
Reference |
2 |
Authors |
von Wartburg JP, Wermoth B. |
Title |
Aldehyde reductase. |
Journal |
In: Jakoby WB (ed). Enzymatic Basis of Detoxication. Vol. 1. New York: Academic Press; 1980. p. 249-260. |
Reference |
|
Authors |
YORK JL, GROLLMAN AP, BUBLITZ C. |
Title |
TPN-L-gluonate dehydrogenase. |
Journal |
|
Other DBs |
ExplorEnz - The Enzyme Database: | 1.1.1.19 |
ExPASy - ENZYME nomenclature database: | 1.1.1.19 |
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