| Entry |
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| Name |
glucuronolactone reductase;
GRase;
gulonolactone dehydrogenase
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| Class |
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
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| Sysname |
L-gulono-1,4-lactone:NADP+ 1-oxidoreductase
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| Reaction(IUBMB) |
L-gulono-1,4-lactone + NADP+ = D-glucurono-3,6-lactone + NADPH + H+ [RN: R03183]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
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| History |
EC 1.1.1.20 created 1961
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| Pathway |
| ec00053 | Ascorbate and aldarate metabolism |
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| Reference |
1 |
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| Authors |
Suzuki K, Mano Y, Shimazono N. |
|---|
| Title |
Conversion of L-gulonolactone to L-ascorbic acid; properties of the microsomal enzyme in rat liver. |
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| Journal |
J Biochem (Tokyo) 48:313-315 (1960) |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 1.1.1.20 |
| ExPASy - ENZYME nomenclature database: | 1.1.1.20 |
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