KEGG ENZYME: 1.1.1.216

ENZYME: 1.1.1.216

Entry

EC 1.1.1.216 Enzyme

Name

farnesol dehydrogenase (NADP+);
NADP+-farnesol dehydrogenase;
farnesol (nicotinamide adenine dinucleotide phosphate) dehydrogenase

Class

Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor

Sysname

(2E,6E)-farnesol:NADP+ 1-oxidoreductase

Reaction(IUBMB)

(2E,6E)-farnesol + NADP+ = (2E,6E)-farnesal + NADPH + H+ [RN:R03264]

Reaction(KEGG)

R03264

Substrate

(2E,6E)-farnesol [CPD:C01126];
NADP+ [CPD:C00006]

Product

(2E,6E)-farnesal [CPD:C03461];
NADPH [CPD:C00005];
H+ [CPD:C00080]

Comment

Also acts, more slowly, on (2Z,6E)-farnesol, geraniol, citronerol and nerol.

History

EC 1.1.1.216 created 1989

Pathway

ec00900

Terpenoid backbone biosynthesis

ec00981

Insect hormone biosynthesis

Orthology

K15890

NADP+-dependent farnesol dehydrogenase

Genes

DME:	Dmel_CG10962(CG10962) Dmel_CG1386(antdh) Dmel_CG3301(CG3301) Dmel_CG40485(CG40485) Dmel_CG40486(CG40486) Dmel_CG8757(CG8757) Dmel_CG9150(CG9150) Dmel_CG9360(CG9360)

DPO:	Dpse_GA10693 Dpse_GA12578 Dpse_GA17238 Dpse_GA21577 Dpse_GA21729 Dpse_GA22691 Dpse_GA23087 Dpse_GA23088 Dpse_GA25891 Dpse_GA26486

DAN:	Dana_GF10960 Dana_GF15405 Dana_GF16364 Dana_GF16365 Dana_GF17260 Dana_GF19119 Dana_GF20253 Dana_GF22156 Dana_GF22157 Dana_GF22361

DER:	6543477 6545569 6549862 6549973 6549974 6551346 6551694 6553336

DPE:	6587226 6587439 6587539 6589226 6597291 6597788 6597841 6598208 6598768 6600343 6602913

DSE:	Dsec_GM10055 Dsec_GM10056 Dsec_GM10850 Dsec_GM11256 Dsec_GM13047 Dsec_GM13691 Dsec_GM15086 Dsec_GM17962 Dsec_GM23885 Dsec_GM24579

DSI:	Dsimw501_GD15972(Dsim_GD15972) Dsimw501_GD15999(Dsim_GD15999) Dsimw501_GD16091(Dsim_GD16091) Dsimw501_GD17575(Dsim_GD17575) Dsimw501_GD19832(Dsim_GD19832) Dsimw501_GD19991(Dsim_GD19991) Dsimw501_GD22600(Dsim_GD22600) Dsimw501_GD23342(Dsim_GD23342) Dsimw501_GD26908(Dsim_GD26908)

DWI:	6641480 6641481 6642370 6644628 6644789 6650327 6650328 6650586 6650587 6650969 6652811 6653036

DYA:	Dyak_GE15259 Dyak_GE15260 Dyak_GE17313 Dyak_GE17424 Dyak_GE17599 Dyak_GE18948 Dyak_GE20052 Dyak_GE25000

DGR:	Dgri_GH10934 Dgri_GH12070 Dgri_GH12228 Dgri_GH12229 Dgri_GH12862 Dgri_GH17647 Dgri_GH18894 Dgri_GH18905 Dgri_GH24588

DMO:	Dmoj_GI10833 Dmoj_GI13477 Dmoj_GI14955 Dmoj_GI14956 Dmoj_GI15259 Dmoj_GI15562 Dmoj_GI15762 Dmoj_GI16085

DAZ:	108609983 108615742 108618236 108618823 108618824 108619049 108619645 108620172

DNV:	108652792 108656080 108656143 108656144 108656698 108657549 108657604

DHE:	111596354 111596716 111598445 111598450 111600180 111602647 111602869 111603126 111604844

DVI:	Dvir_GJ12118 Dvir_GJ14440 Dvir_GJ14831 Dvir_GJ14832 Dvir_GJ15175 Dvir_GJ18619 Dvir_GJ18923 Dvir_GJ18924 Dvir_GJ23779

AGA:	AgaP_AGAP005500 AgaP_AGAP005503 AgaP_AGAP005645

AAG:	23687599 23687722 23687740 23687872

CQU:	CpipJ_CPIJ004599 CpipJ_CPIJ016920 CpipJ_CPIJ016922 CpipJ_CPIJ016923

AME:

725489

BIM:	100741907 100743402 100747182 100748684

BTER:

100647945 100650886

SOC:	105199354 105201878

MPHA:

105830613 105835413

AEC:	105144197 105151157 105151159

ACEP:

105617802 105619320

PBAR:

105422266 105433187

HST:	105180950 105184803 105187876

DQU:	106748262 106748778

CFO:	105248924 105248933 105249644 105254709 105258823 109609829

LHU:	105672418 105679444

PGC:	109853189 109854508 109860812

OBO:	105275997 105288130

PCF:	106785511 106786151 106791161 106792782

NVI:

100121837

MDL:	103569447 103575761 103577122

TCA:	100142466 656859 657029 657192 657270 657342 657419 657969 658287 658434 658587 658671 658696 659209 659494

DPA:	109532835 109534023 109534024 109534026 109534027 109534635 109534645 109536884 109537328 109542161 109542162 109545029 109546116

NVL:	108563274 108563277 108563292 108563293 108563294 108563689 108565751 108565757 108565810 108565825 108565851 108565862 108565874

BMOR:

101735830 101741066 101743359

DPL:	KGM_212697

PMAC:

106709858

PRAP:

110991447

HAW:	110370909 110372216

TNL:	113498808 113503048

PXY:	105386204 105398348

API:	100159964 100160714 100162026 100162229 100164304 100168880 100169616 100301633 100571213

DNX:	107161331 107162000 107163401 107164395 107167415 107167735

AGS:	114119318 114119988 114119989 114120739 114129457 114129953

CLEC:

106669480 106670299

PHU:	Phum_PHUM184020

ZNE:	110833055 110834646 110834649 110834652

» show all

Reference

Authors

Inoue, H., Tsuji, H. and Uritani, I.

Title

Characterization and activity change of farnesol dehydrogenase in black rot fungus-infected sweet-potato.

Journal

Agric Biol Chem 48:733-738 (1984)

Other DBs

ExplorEnz - The Enzyme Database:

1.1.1.216

IUBMB Enzyme Nomenclature:

1.1.1.216

ExPASy - ENZYME nomenclature database:

1.1.1.216

BRENDA, the Enzyme Database:

1.1.1.216

CAS:	89089-75-8 90804-55-0

DBGET integrated database retrieval system