KEGG   ENZYME: 1.1.1.216Help
Entry
EC 1.1.1.216                Enzyme                                 

Name
farnesol dehydrogenase (NADP+);
NADP+-farnesol dehydrogenase;
farnesol (nicotinamide adenine dinucleotide phosphate) dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
(2E,6E)-farnesol:NADP+ 1-oxidoreductase
Reaction(IUBMB)
(2E,6E)-farnesol + NADP+ = (2E,6E)-farnesal + NADPH + H+ [RN:R03264]
Reaction(KEGG)
Substrate
(2E,6E)-farnesol [CPD:C01126];
NADP+ [CPD:C00006]
Product
(2E,6E)-farnesal [CPD:C03461];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
Also acts, more slowly, on (2Z,6E)-farnesol, geraniol, citronerol and nerol.
History
EC 1.1.1.216 created 1989
Pathway
ec00900  Terpenoid backbone biosynthesis
ec00909  Sesquiterpenoid and triterpenoid biosynthesis
ec00981  Insect hormone biosynthesis
ec01130  Biosynthesis of antibiotics
Orthology
K15890  NADP+-dependent farnesol dehydrogenase
Genes
DME: Dmel_CG10962(CG10962) Dmel_CG1386(antdh) Dmel_CG3301(CG3301) Dmel_CG40485(CG40485) Dmel_CG40486(CG40486) Dmel_CG8757(CG8757) Dmel_CG9150(CG9150) Dmel_CG9360(CG9360)
DPO: Dpse_GA10693 Dpse_GA12578 Dpse_GA17238 Dpse_GA21577 Dpse_GA21729 Dpse_GA22691 Dpse_GA23087 Dpse_GA23088 Dpse_GA25891 Dpse_GA26486
DAN: Dana_GF10960 Dana_GF15405 Dana_GF16364 Dana_GF16365 Dana_GF17260 Dana_GF19119 Dana_GF20253 Dana_GF22156 Dana_GF22157 Dana_GF22361
DER: 6543477 6545569 6549862 6549973 6549974 6551346 6551694 6553336
DPE: 6587226 6587439 6587539 6589226 6597291 6597788 6597841 6598208 6598768 6600343 6602913
DSE: Dsec_GM10055 Dsec_GM10056 Dsec_GM10850 Dsec_GM11256 Dsec_GM13047 Dsec_GM13691 Dsec_GM15086 Dsec_GM17962 Dsec_GM23885 Dsec_GM24579
DSI: Dsimw501_GD15972(Dsim_GD15972) Dsimw501_GD15999(Dsim_GD15999) Dsimw501_GD16091(Dsim_GD16091) Dsimw501_GD17575(Dsim_GD17575) Dsimw501_GD19832(Dsim_GD19832) Dsimw501_GD19991(Dsim_GD19991) Dsimw501_GD22600(Dsim_GD22600) Dsimw501_GD23342(Dsim_GD23342) Dsimw501_GD26908(Dsim_GD26908)
DWI: 6641480 6641481 6642370 6644628 6644789 6650327 6650328 6650586 6650587 6650969 6652811 6653036
DYA: Dyak_GE15259 Dyak_GE15260 Dyak_GE17313 Dyak_GE17424 Dyak_GE17599 Dyak_GE18948 Dyak_GE20052 Dyak_GE25000
DGR: Dgri_GH10934 Dgri_GH12070 Dgri_GH12228 Dgri_GH12229 Dgri_GH12862 Dgri_GH17647 Dgri_GH18894 Dgri_GH18905 Dgri_GH24588
DMO: Dmoj_GI10833 Dmoj_GI13477 Dmoj_GI14955 Dmoj_GI14956 Dmoj_GI15259 Dmoj_GI15562 Dmoj_GI15762 Dmoj_GI16085
DVI: Dvir_GJ12118 Dvir_GJ14440 Dvir_GJ14831 Dvir_GJ14832 Dvir_GJ15175 Dvir_GJ18619 Dvir_GJ18923 Dvir_GJ18924 Dvir_GJ23779
MDE: 101888729 101891883 101892059 101892231 101892484 101892558 101892573 101892919 101892999 101893249 101896442 101896457 101896812 101898950 101899129 101899302 101899478 101899636 101899804 105262085 105262086
AGA: AgaP_AGAP005500 AgaP_AGAP005503 AgaP_AGAP005645
AAG: 23687599 23687722 23687740 23687872
CQU: CpipJ_CPIJ004599 CpipJ_CPIJ016920 CpipJ_CPIJ016922 CpipJ_CPIJ016923
BIM: 100741907 100743402 100747182 100748684
BTER: 100647945 100650886
SOC: 105199354 105201878
AEC: 105144197 105151159
ACEP: 105617802 105619320
PBAR: 105422266 105433187
HST: 105180950 105184803 105187876
DQU: 106748262
CFO: 105248933 105249644 105254709 105258823
LHU: 105672418
PGC: 109853189 109854508 109860812
PCF: 106785511 106786151 106791161 106792782
NVI: 100121837
MDL: 103569447 103577122
TCA: 100142466 656859 657029 657192 657270 657342 657419 657969 658287 658434 658587 658671 658696 659209 659494
DPA: 109532835 109534023 109534024 109534026 109534027 109534635 109534645 109536884 109537328 109542161 109542162 109545029 109546116
NVL: 108563274 108563277 108563292 108563293 108563294 108563689 108565751 108565757 108565810 108565825 108565851 108565862 108565874
BMOR: 101735830 101741066 101743359
DPL: KGM_212697
PMAC: 106709858
PRAP: 110991447
HAW: 110370909 110372216
PXY: 105386204 105398348
API: 100159964 100160714 100162026 100162229 100164304 100168880 100169616 100301633 100571213
DNX: 107161331 107162000 107163401 107164395 107167415 107167735
CLEC: 106669480 106670299
PHU: Phum_PHUM184020
ZNE: 110833055 110834646 110834649 110834652
 » show all
Taxonomy
Reference
1
  Authors
Inoue, H., Tsuji, H. and Uritani, I.
  Title
Characterization and activity change of farnesol dehydrogenase in black rot fungus-infected sweet-potato.
  Journal
Agric Biol Chem 48:733-738 (1984)
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.216
IUBMB Enzyme Nomenclature: 1.1.1.216
ExPASy - ENZYME nomenclature database: 1.1.1.216
BRENDA, the Enzyme Database: 1.1.1.216
CAS: 89089-75-8 90804-55-0

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Pathway (8)   
   KEGG PATHWAY (8)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG REACTION (1)   
   KEGG RCLASS (1)   
Gene (386)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (250)   
   EGENES (135)   
Protein sequence (13)   
   UniProt (10)   
   SWISS-PROT (2)   
   RefSeq(pep) (1)   
DNA sequence (13)   
   RefSeq(nuc) (1)   
   GenBank (7)   
   EMBL (5)   
All databases (427)   

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