KEGG   ENZYME: 1.1.1.216Help
Entry
EC 1.1.1.216                Enzyme                                 

Name
farnesol dehydrogenase (NADP+);
NADP+-farnesol dehydrogenase;
farnesol (nicotinamide adenine dinucleotide phosphate) dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
(2E,6E)-farnesol:NADP+ 1-oxidoreductase
Reaction(IUBMB)
(2E,6E)-farnesol + NADP+ = (2E,6E)-farnesal + NADPH + H+ [RN:R03264]
Reaction(KEGG)
Substrate
(2E,6E)-farnesol [CPD:C01126];
NADP+ [CPD:C00006]
Product
(2E,6E)-farnesal [CPD:C03461];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
Also acts, more slowly, on (2Z,6E)-farnesol, geraniol, citronerol and nerol.
History
EC 1.1.1.216 created 1989
Pathway
ec00900  Terpenoid backbone biosynthesis
ec00909  Sesquiterpenoid and triterpenoid biosynthesis
ec00981  Insect hormone biosynthesis
ec01130  Biosynthesis of antibiotics
Orthology
K15890  NADP+-dependent farnesol dehydrogenase
Genes
DME: Dmel_CG10962(CG10962) Dmel_CG1386(antdh) Dmel_CG3301(CG3301) Dmel_CG40485(CG40485) Dmel_CG40486(CG40486) Dmel_CG8757(CG8757) Dmel_CG9150(CG9150) Dmel_CG9360(CG9360)
DPO: Dpse_GA10693 Dpse_GA12578 Dpse_GA17238 Dpse_GA21577 Dpse_GA21729 Dpse_GA22691 Dpse_GA23087 Dpse_GA23088 Dpse_GA25891 Dpse_GA26486
DAN: Dana_GF10960 Dana_GF15405 Dana_GF16364 Dana_GF16365 Dana_GF17260 Dana_GF19119 Dana_GF20253 Dana_GF22156 Dana_GF22157 Dana_GF22361
DER: 6543477 6545569 6549862 6549973 6549974 6551346 6551694 6553336
DPE: 6587226 6587439 6587539 6589226 6597291 6597788 6597841 6598208 6598768 6600343 6602913
DSE: Dsec_GM10055 Dsec_GM10056 Dsec_GM10850 Dsec_GM11256 Dsec_GM13047 Dsec_GM13691 Dsec_GM15086 Dsec_GM17962 Dsec_GM23885 Dsec_GM24579
DSI: Dsimw501_GD15972(Dsim_GD15972) Dsimw501_GD15999(Dsim_GD15999) Dsimw501_GD16091(Dsim_GD16091) Dsimw501_GD17575(Dsim_GD17575) Dsimw501_GD19832(Dsim_GD19832) Dsimw501_GD19991(Dsim_GD19991) Dsimw501_GD22600(Dsim_GD22600) Dsimw501_GD23342(Dsim_GD23342) Dsimw501_GD26908(Dsim_GD26908)
DWI: 6641480 6641481 6642370 6644628 6644789 6650327 6650328 6650586 6650587 6650969 6652811 6653036
DYA: Dyak_GE15259 Dyak_GE15260 Dyak_GE17313 Dyak_GE17424 Dyak_GE17599 Dyak_GE18948 Dyak_GE20052 Dyak_GE25000
DGR: Dgri_GH10934 Dgri_GH12070 Dgri_GH12228 Dgri_GH12229 Dgri_GH12862 Dgri_GH17647 Dgri_GH18894 Dgri_GH18905 Dgri_GH24588
DQU: 106748262
LHU: 105672418
NVI: 100121837
PMAC: 106709858
PRAP: 110991447
 » show all
Taxonomy
Reference
1
  Authors
Inoue, H., Tsuji, H. and Uritani, I.
  Title
Characterization and activity change of farnesol dehydrogenase in black rot fungus-infected sweet-potato.
  Journal
Agric Biol Chem 48:733-738 (1984)
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.216
IUBMB Enzyme Nomenclature: 1.1.1.216
ExPASy - ENZYME nomenclature database: 1.1.1.216
BRENDA, the Enzyme Database: 1.1.1.216
CAS: 89089-75-8 90804-55-0

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