KEGG ENZYME: 1.1.1.216

ENZYME: 1.1.1.216

Entry

EC 1.1.1.216 Enzyme

Name

farnesol dehydrogenase (NADP+);
NADP+-farnesol dehydrogenase;
farnesol (nicotinamide adenine dinucleotide phosphate) dehydrogenase

Class

Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor

Sysname

(2E,6E)-farnesol:NADP+ 1-oxidoreductase

Reaction(IUBMB)

(2E,6E)-farnesol + NADP+ = (2E,6E)-farnesal + NADPH + H+ [RN:R03264]

Reaction(KEGG)

R03264

Substrate

(2E,6E)-farnesol [CPD:C01126];
NADP+ [CPD:C00006]

Product

(2E,6E)-farnesal [CPD:C03461];
NADPH [CPD:C00005];
H+ [CPD:C00080]

Comment

Also acts, more slowly, on (2Z,6E)-farnesol, geraniol, citronerol and nerol.

History

EC 1.1.1.216 created 1989

Pathway

ec00900

Terpenoid backbone biosynthesis

ec00981

Insect hormone biosynthesis

ec01110

Biosynthesis of secondary metabolites

Orthology

K15890

NADP+-dependent farnesol dehydrogenase

Genes

DME:	Dmel_CG10962(CG10962) Dmel_CG1386(antdh) Dmel_CG3301(CG3301) Dmel_CG40485(CG40485) Dmel_CG40486(CG40486) Dmel_CG8757(CG8757) Dmel_CG9150(CG9150)

DER:	6543477 6545569 6549862 6549973 6549974 6551694 6553336

DSE:	6605603 6613582 6617640 6619743 6620024 6620089 6620090

DSI:	Dsimw501_GD15999(Dsim_GD15999) Dsimw501_GD16091(Dsim_GD16091) Dsimw501_GD17575(Dsim_GD17575) Dsimw501_GD19991(Dsim_GD19991) Dsimw501_GD22600(Dsim_GD22600) Dsimw501_GD23342(Dsim_GD23342) Dsimw501_GD26908(Dsim_GD26908)

DYA:	Dyak_GE15259 Dyak_GE15260 Dyak_GE17313 Dyak_GE17424 Dyak_GE18948 Dyak_GE20052 Dyak_GE25000

DAN:	6498214 6500045 6501882 6504823 6504824 6505023

DSR:	110176041 110180365 110180367 110182109 110182689 110187933 110188271 110190274

DPO:	Dpse_GA12578 Dpse_GA17238 Dpse_GA21577 Dpse_GA22691 Dpse_GA23087 Dpse_GA23088 Dpse_GA25891

DPE:	6587226 6589226 6597291 6597788 6597841 6598208 6598768 6602913

DMN:	108150850 108151202 108154295 108157162 108157803 108162957 108165133 108165134

DWI:	6641480 6641481 6642370 6644789 6650969 6652811 6653036

DGR:	Dgri_GH10934 Dgri_GH12070 Dgri_GH12228 Dgri_GH12229 Dgri_GH12862 Dgri_GH17647 Dgri_GH18894 Dgri_GH18905

DMO:	Dmoj_GI10833 Dmoj_GI13477 Dmoj_GI14955 Dmoj_GI14956 Dmoj_GI15562 Dmoj_GI15762 Dmoj_GI16085

DAZ:	108609983 108615742 108618823 108618824 108619049 108619645 108620172

DNV:	108652792 108656080 115563334 115564232 115565192

DHE:	111596354 111598445 111598450 111600180 111602647 111603126 111604844

DVI:	6628165 6631803 6631854 6631855 6634765 6635194 6635533

MDE:	101888729 101891883 101892059 101892484 101892558 101892573 101892919 101892999 101893249 101896442 101896457 101896812 101898950 101899129 101899302 101899478 101899636 101899804

LCQ:	111678705 111678707 111679994 111679995 111679996 111679997 111679998 111681916 111682725 111683024 111683775 111683933 111686785 111686935 111686937 111686938 111686940 111686941 111686942

AGA:	AgaP_AGAP005499 AgaP_AGAP005500 AgaP_AGAP005501 AgaP_AGAP005502 AgaP_AGAP005503 AgaP_AGAP005645 AgaP_AGAP010311

AAG:	110674007 110680302 23687599 23687722 23687740 23687872 5570715 5572258 5572855 5573679 5573680

CQU:	CpipJ_CPIJ001561 CpipJ_CPIJ002517 CpipJ_CPIJ002522 CpipJ_CPIJ004598 CpipJ_CPIJ004599 CpipJ_CPIJ004600 CpipJ_CPIJ004602 CpipJ_CPIJ004603 CpipJ_CPIJ005654 CpipJ_CPIJ005655 CpipJ_CPIJ005656 CpipJ_CPIJ016920 CpipJ_CPIJ016921 CpipJ_CPIJ016922 CpipJ_CPIJ016923 CpipJ_CPIJ020041

AME:	406147 412458

BIM:	100742025 100743402 100747302 100748185

BTER:

100644832 100647945 100648073

CCAL:

108623174 108630799 108630800

OBB:	114877440 114877441 114880112 114880113

SOC:	105198426 105199354

MPHA:

105835413 105838190

AEC:	105144197 105144228

PBAR:

105433698

VEM:

105561928

HST:	105183110 105184798 105184803 105187876

DQU:	106745641 106748262

CFO:	105249644 105254709

LHU:

105673536

PGC:	109853189 109853191 109853288 109854507 109854508 109860758 109860887

OBO:	105274794 105274796 105275997 113561435 113563372

PCF:	106786151 106791135 106791161 106791432 106792782

NVI:	100115586 100116170 100116955 100117064 100117099 100118150 100120166 100120547 100120753 100120843 100121819(SDR) 100121837 100122966 100678345

MDL:	103569447 103569449 103577122

TCA:	100142466 655111 656859 657029 657192 657270 657342 657419 657969 658287 658434 658587 658671 658696 659209 659494

DPA:	109532835 109532836 109534023 109534024 109534026 109534027 109534635 109534645 109536884 109537328 109538476 109542161 109542162 109544759 109544952 109545029 109546116

ATD:	109597244 109599757 109601194 109601197 109601199 109604250 109604251 109604256 109604764 109608105

NVL:	108563274 108563277 108563292 108563293 108563294 108563689 108565751 108565757 108565810 108565825 108565851 108565862 108565874

BMOR:

101735830 101741066

BMAN:

114247690 114247691 114247722

DPL:	KGM_212697

PMAC:

106709858

PRAP:

110991447

HAW:	110370909 110372216

TNL:	113498808 113503048

PXY:	105386204 105398348

API:	100159964 100160714 100160733 100162026 100162229 100164304 100166294 100168880 100169616 100301633 100571213

DNX:	107161331 107162000 107162475 107163401 107164395 107165835 107167415 107167735

AGS:	114119318 114119988 114119989 114120739 114120740 114121527 114122163 114122164 114123857 114129457 114129953

RMD:	113550480 113551435 113551436 113551753 113552079 113553672 113553821 113555909 113556918 113560812 113561249

BTAB:

109032727 109037418

CLEC:

106662924 106669481 106670299

PHU:	Phum_PHUM184020

ZNE:	110828106 110833055 110834646 110834649 110834652 110834654 110838180

» show all

Reference

Authors

Inoue, H., Tsuji, H. and Uritani, I.

Title

Characterization and activity change of farnesol dehydrogenase in black rot fungus-infected sweet-potato.

Journal

Agric Biol Chem 48:733-738 (1984)

Other DBs

ExplorEnz - The Enzyme Database:

1.1.1.216

IUBMB Enzyme Nomenclature:

1.1.1.216

ExPASy - ENZYME nomenclature database:

1.1.1.216

BRENDA, the Enzyme Database:

1.1.1.216

CAS:	89089-75-8 90804-55-0

DBGET integrated database retrieval system