KEGG   ENZYME: 1.1.1.287
Entry
EC 1.1.1.287                Enzyme                                 
Name
D-arabinitol dehydrogenase (NADP+);
NADP+-dependent D-arabitol dehydrogenase;
ARD1p;
D-arabitol dehydrogenase 1
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
D-arabinitol:NADP+ oxidoreductase
Reaction(IUBMB)
(1) D-arabinitol + NADP+ = D-xylulose + NADPH + H+ [RN:R07143];
(2) D-arabinitol + NADP+ = D-ribulose + NADPH + H+ [RN:R07144]
Reaction(KEGG)
R07143 R07144
Substrate
D-arabinitol [CPD:C01904];
NADP+ [CPD:C00006]
Product
D-xylulose [CPD:C00310];
NADPH [CPD:C00005];
H+ [CPD:C00080];
D-ribulose [CPD:C00309]
Comment
The enzyme from the rust fungus Uromyces fabae can use D-arabinitol and D-mannitol as substrates in the forward direction and D-xylulose, D-ribulose and, to a lesser extent, D-fructose as substrates in the reverse direction. This enzyme carries out the reactions of both EC 1.1.1.11, D-arabinitol 4-dehydrogenase and EC 1.1.1.250, D-arabinitol 2-dehydrogenase, but unlike them, uses NADP+ rather than NAD+ as cofactor. D-Arabinitol is capable of quenching reactive oxygen species involved in defense reactions of the host plant.
History
EC 1.1.1.287 created 2005
Pathway
ec00040  Pentose and glucuronate interconversions
ec01100  Metabolic pathways
Orthology
K17818  D-arabinitol dehydrogenase (NADP+)
Genes
BFO118404134 118407503 118409407 118409409
BBEL109469863 109485904 109485905 109485906
CIN100181990 100184356
TCA656777 656868 656956
DPA109543751
SOY115883327 115883331
ATD109606193 109606521
CSET123319748
AGB108904881
LDC111512233 111512234 111512235
APLN108733757 108743068
PPYR116161257 116162229 116162524
OTU111417893
BMOR732960
BMAN114244156
MSEX115446355
DPLKGM_208136
BANY112045129
NIQ126778895 126778897
PMAC106716118
PPOT106109593
PXU106124335
PRAP111000494
ZCE119838172
HAW110382525
HZE124643775
TNL113498593
SLIU111354833
OFU114365938
PXY105395266 105395281
HHAL106679170
NLU111059478 111059479
FOC113211191 113215677
TPAL117641356 117653082
ZNE110829191 110829307
CSEC111868664 111869992
EAF111702938
PPOI119102375 119107173 119113973
LGILOTGIDRAFT_122580 LOTGIDRAFT_159773 LOTGIDRAFT_188066
NVE5507187 5519969
EPA110231764
ATEN116287780 116298403
ADF107355656
AMIL114963647
PDAM113684290 113684326
SPIS111343963 111343964
DGT114536034
XEN124449516
HMG100204180
TADTRIADDRAFT_54628
MGRMGG_01114
PPEIPpBr36_08024
TMNUCRPA7_4120
SSCKSPSK_09459
NHENECHADRAFT_78747
MAWMAC_06529
MAJMAA_07660
PLJVFPFJ_06970
VALVDBG_05181
VDAVDAG_08929
CFJCFIO01_05463
CLUPCLUP02_01181
CHIGCH63R_10122
SAPOSAPIO_CDS4891
ELAUCREL1_1758
PFYPFICI_08899
SSLSS1G_10495
BFUBCIN_14g04580
MBEMBM_09044
PSCOLY89DRAFT_746517 LY89DRAFT_770545
GLZGLAREA_11059
ANIAN0443.2
AFMAFUA_1G04620
ACTACLA_030040
NFINFIA_020120
AORAO090003000888
ANGANI_1_452014(An01g03480) ANI_1_552044(An05g02000)
AFVAFLA_000788
ALUCAKAW2_20514S AKAW2_81343A
ACHEACHE_11636S
APUUAPUU_11613S APUU_21187S
PCSPc16g08460
TMFPMAA_054360
TRGTRUGW13939_00501 TRUGW13939_01187
CIMCIMG_04945
CPWCPC735_069350
UREUREG_06606
PBLPAAG_00966
PBNPADG_03859
ABEARB_06173
TVETRV_00619
AJEHCAG_03605
BGHBDBG_05375
PNOSNOG_10906
PTEPTT_18102
BZECOCCADRAFT_29730
BSCCOCSADRAFT_136377
BORCOCMIDRAFT_93489
AALTCC77DRAFT_931060
BCOMBAUCODRAFT_204777
NPAUCRNP2_4574
TMLGSTUM_00002324001
CNECNC06260
CNBCNBC0940
CNGCNAG_01558
CGICGB_C1260W
TMSTREMEDRAFT_40868
TASAA1Q1_00927
PPLPOSPLDRAFT_87428
TVSTRAVEDRAFT_30336 TRAVEDRAFT_73393
DSQDICSQDRAFT_162455 DICSQDRAFT_179082 DICSQDRAFT_181925 DICSQDRAFT_54950
PCOPHACADRAFT_142124 PHACADRAFT_253802
SHSSTEHIDRAFT_103570 STEHIDRAFT_84864
HIRHETIRDRAFT_156927 HETIRDRAFT_461044
PSQPUNSTDRAFT_52317 PUNSTDRAFT_68061
ADLAURDEDRAFT_156498
FMEFOMMEDRAFT_103362 FOMMEDRAFT_165934
GTRGLOTRDRAFT_104555 GLOTRDRAFT_111731 GLOTRDRAFT_63257
LBCLACBIDRAFT_248925
CCICC1G_05273
ABPAGABI1DRAFT116829(AGABI1DRAFT_116829) AGABI1DRAFT46050(AGABI1DRAFT_46050)
ABVAGABI2DRAFT145143(AGABI2DRAFT_145143) AGABI2DRAFT194619(AGABI2DRAFT_194619)
PCUBJR316_0010009 JR316_0010045
MRRMoror_10616 Moror_7142 Moror_7157
MOREE1B28_004931 E1B28_008305
SCMSCHCO_02636705(SCHCODRAFT_02636705)
CPUTCONPUDRAFT_109782 CONPUDRAFT_92430
SLASERLADRAFT_345461 SERLADRAFT_457148
PGRPGTG_20122 PGTG_22572
MLRMELLADRAFT_46902
LCKHN018_01245
PNPIJ22_33020
PLYCGXP70_22330
CCHLFPL14_17170
LJIELX58_04790
CFMBJL90_00115
FPLAA4U99_17855
OBJEIO64_11180
ETMCE91St48_33740(ydjJ)
MSMMSMEG_1370
MSGMSMEI_1331
MSBLJ00_06830
MSNLI99_06830
MSHLI98_06830
SRCM271_42350
MSEDE3O41_04265
AGMDCE93_00255
ARTArth_1823
PHWG7075_18115
PEIH9L10_01045
NABB1sIIB91_04945
IAGIgag_0313
 » show all
Reference
1  [PMID:15796718]
  Authors
Link T, Lohaus G, Heiser I, Mendgen K, Hahn M, Voegele RT
  Title
Characterization of a novel NADP(+)-dependent D-arabitol dehydrogenase from the plant pathogen Uromyces fabae.
  Journal
Biochem J 389:289-95 (2005)
DOI:10.1042/BJ20050301
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.287
IUBMB Enzyme Nomenclature: 1.1.1.287
ExPASy - ENZYME nomenclature database: 1.1.1.287
BRENDA, the Enzyme Database: 1.1.1.287

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