KEGG   ENZYME: 1.1.1.288Help
Entry
EC 1.1.1.288                Enzyme                                 

Name
xanthoxin dehydrogenase;
xanthoxin oxidase;
ABA2
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
xanthoxin:NAD+ oxidoreductase
Reaction(IUBMB)
xanthoxin + NAD+ = abscisic aldehyde + NADH + H+ [RN:R06954]
Reaction(KEGG)
Substrate
xanthoxin [CPD:C13453];
NAD+ [CPD:C00003]
Product
abscisic aldehyde [CPD:C13455];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
Requires a molybdenum cofactor for activity. NADP+ cannot replace NAD+ and short-chain alcohols such as ethanol, isopropanol, butanol and cyclohexanol cannot replace xanthoxin as substrate [3]. Involved in the abscisic-acid biosynthesis pathway in plants, along with EC 1.2.3.14 (abscisic-aldehyde oxidase), EC 1.13.11.51 (9-cis-epoxycarotenoid dioxygenase) and EC 1.14.13.93 [(+)-abscisic acid 8'-hydroxylase]. Abscisic acid is a sesquiterpenoid plant hormone that is involved in the control of a wide range of essential physiological processes, including seed development, germination and responses to stress [3].
History
EC 1.1.1.288 created 2005
Pathway
ec00906  Carotenoid biosynthesis
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K09841  xanthoxin dehydrogenase
Genes
RSS: 109442472
ATH: AT1G52340(ABA2)
ALY: ARALYDRAFT_474354
CRB: 17896886
CSAT: 104758555 104778156
EUS: EUTSA_v10011636mg
BRP: 103832798 103871215
BNA: 106345736 106390565
BOE: 106300040
THJ: 104821959
CPAP: 110815871
CIT: 102577974(ABA2)
TCC: 18585758
GRA: 105783205
EGR: 104454559
CAM: 101515018
ADU: 107471843
AIP: 107622404
LJA: Lj0g3v0091119.1(Lj0g3v0091119.1)
LANG: 109335868
FVE: 101292810
PPER: 18785370
PMUM: 103343399
ZJU: 107417757
CSV: 101219413
CMO: 103503321
MCHA: 111024504
CMAX: 111489670
CMOS: 111445228
CPEP: 111808179
JCU: 105631198
HBR: 110661036
POP: 7487015
VVI: 100265470
SLY: 100750250(SlscADH1) 101254297 101254591
INI: 109155970
SIND: 105172159
OEU: 111410241
HAN: 110925709
DCR: 108206649
NNU: 104612004
OSA: 4334535
DOSA: Os03t0810800-01(Os03g0810800)
OBR: 102708142
BDI: 100827045
ATS: 109784728(LOC109784728)
SBI: 8057083
ZMA: 100282128(sca1)
MUS: 103981080
DCT: 110111993
AOF: 109848475
ATR: 18433242
 » show all
Taxonomy
Reference
1  [PMID:16666262]
  Authors
Sindhu RK, Walton DC.
  Title
Xanthoxin Metabolism in Cell-free Preparations from Wild Type and Wilty Mutants of Tomato.
  Journal
Plant Physiol 88:178-182 (1988)
Reference
2  [PMID:9159947]
  Authors
Schwartz SH, Leon-Kloosterziel KM, Koornneef M, Zeevaart JA.
  Title
Biochemical characterization of the aba2 and aba3 mutants in Arabidopsis thaliana.
  Journal
Plant Physiol 114:161-6 (1997)
  Sequence
[ath:AT1G52340]
Reference
3  [PMID:12172025]
  Authors
Gonzalez-Guzman M, Apostolova N, Belles JM, Barrero JM, Piqueras P, Ponce MR, Micol JL, Serrano R, Rodriguez PL.
  Title
The short-chain alcohol dehydrogenase ABA2 catalyzes the conversion of xanthoxin to abscisic aldehyde.
  Journal
Plant Cell 14:1833-46 (2002)
DOI:10.1105/tpc.002477
  Sequence
[ath:AT1G52340]
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.288
IUBMB Enzyme Nomenclature: 1.1.1.288
ExPASy - ENZYME nomenclature database: 1.1.1.288
BRENDA, the Enzyme Database: 1.1.1.288
CAS: 129204-37-1

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