Entry |
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Name |
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Class |
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
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Sysname |
D-glucitol:NADP+ oxidoreductase
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Reaction(IUBMB) |
D-glucitol + NADP+ = L-sorbose + NADPH + H+ [RN: R07346]
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Reaction(KEGG) |
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Substrate |
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Product |
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Comment |
The reaction occurs predominantly in the reverse direction. This enzyme can also convert D-fructose into D-mannitol, but more slowly. Belongs in the short-chain dehydrogenase family.
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History |
EC 1.1.1.289 created 2006
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Pathway |
ec00051 | Fructose and mannose metabolism |
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Orthology |
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Genes |
» show all
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Reference |
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Authors |
Greenberg JR, Price NP, Oliver RP, Sherman F, Rustchenko E. |
Title |
Candida albicans SOU1 encodes a sorbose reductase required for L-sorbose utilization. |
Journal |
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Sequence |
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Reference |
2 |
Authors |
Greenberg, J.R., Price, N.P., Oliver, R.P., Sherman, F. and Rustchenko, E. |
Title |
Erratum report: Candida albicans SOU1 encodes a sorbose reductase required for L-sorbose utilization. |
Journal |
Yeast 22:1171 (2005) |
Reference |
3 |
Authors |
Sugisawa, T., Hoshino, T. and Fujiwara, A. |
Title |
Purification and properties of NADPH-linked L-sorbose reductase from Gluconobacter melanogenus N44-1. |
Journal |
Agric Biol Chem 55:2043-2049 (1991) |
Reference |
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Authors |
Shinjoh M, Tazoe M, Hoshino T. |
Title |
NADPH-dependent L-sorbose reductase is responsible for L-sorbose assimilation in Gluconobacter suboxydans IFO 3291. |
Journal |
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Sequence |
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Other DBs |
ExPASy - ENZYME nomenclature database: | 1.1.1.289 |
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