KEGG   ENZYME: 1.1.1.296
Entry
EC 1.1.1.296                Enzyme                                 

Name
dihydrocarveol dehydrogenase;
carveol dehydrogenase (ambiguous)
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
menth-8-en-2-ol:NAD+ oxidoreductase
Reaction(IUBMB)
menth-8-en-2-ol + NAD+ = menth-8-en-2-one + NADH + H+ [RN:R08918]
Reaction(KEGG)
Substrate
menth-8-en-2-ol [CPD:C18017];
NAD+ [CPD:C00003]
Product
menth-8-en-2-one [CPD:C18018];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
This enzyme from the Gram-positive bacterium Rhodococcus erythropolis DCL14 forms part of the carveol and dihydrocarveol degradation pathway. The enzyme accepts all eight stereoisomers of menth-8-en-2-ol as substrate, although some isomers are converted faster than others. The preferred substrates are (+)-neoisodihydrocarveol, (+)-isodihydrocarveol, (+)-dihydrocarveol and (-)-isodihydrocarveol.
History
EC 1.1.1.296 created 2008
Pathway
ec00903  Limonene and pinene degradation
Reference
1  [PMID:10832640]
  Authors
van der Werf MJ, Boot AM
  Title
Metabolism of carveol and dihydrocarveol in Rhodococcus erythropolis DCL14.
  Journal
Microbiology 146 ( Pt 5):1129-41 (2000)
DOI:10.1099/00221287-146-5-1129
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.296
IUBMB Enzyme Nomenclature: 1.1.1.296
ExPASy - ENZYME nomenclature database: 1.1.1.296
BRENDA, the Enzyme Database: 1.1.1.296

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Pathway (2)   
   KEGG PATHWAY (2)   
Chemical substance (17)   
   KEGG COMPOUND (17)   
Chemical reaction (10)   
   KEGG REACTION (9)   
   KEGG RCLASS (1)   
All databases (29)   

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