KEGG   ENZYME: 1.1.1.308
Entry
EC 1.1.1.308                Enzyme                                 
Name
sulfopropanediol 3-dehydrogenase;
DHPS 3-dehydrogenase (sulfolactate forming);
2,3-dihydroxypropane-1-sulfonate 3-dehydrogenase (sulfolactate forming);
dihydroxypropanesulfonate 3-dehydrogenase;
hpsN (gene name)
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
(R)-2,3-dihydroxypropane-1-sulfonate:NAD+ 3-oxidoreductase
Reaction(IUBMB)
(R)-2,3-dihydroxypropane-1-sulfonate + 2 NAD+ + H2O = (R)-3-sulfolactate + 2 NADH + 2 H+ [RN:R09545]
Reaction(KEGG)
R09545
Substrate
(R)-2,3-dihydroxypropane-1-sulfonate [CPD:C19675];
NAD+ [CPD:C00003];
H2O [CPD:C00001]
Product
(R)-3-sulfolactate [CPD:C11537];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
The enzyme is involved in degradation of (R)-2,3-dihydroxypropanesulfonate.
History
EC 1.1.1.308 created 2011
Orthology
K15509  sulfopropanediol 3-dehydrogenase
Genes
ECLXLI66_17165 LI66_17190
ECLYLI62_18750 LI62_18775
ECLOENC_28830
EXFBFV63_16780 BFV63_16805
ECANCWI88_05315(hisD) CWI88_05340(hisD)
ENSHWQ15_02605(hisD) HWQ15_02630(hisD)
ENKLOC22_05435(hisD) LOC22_05460(hisD)
EAEEAE_05825
EARCCG32834
LAXAPT61_12775 APT61_12800
LEIC2U54_14965(hisD) C2U54_14990(hisD)
LEHC3F35_01725(hisD)
LEEDVA44_13790(hisD)
LERGNG29_09810(hisD) GNG29_09835(hisD)
LEAGNG26_09515(hisD) GNG26_09540(hisD)
LEFLJPFL01_1827 LJPFL01_1832
LEWDAI21_16950(hisD)
BAGEBADSM9389_23870(hisD) BADSM9389_23920(hisD)
BFTMNO13_09305(hisD) MNO13_09335(hisD)
AHNNCTC12129_02753(hisD_1)
ASUBNLZ15_10135(hisD)
SGOEA8O29_004590(hisD) A8O29_004615(hisD)
GQUAWC35_21415
EAMEGXP68_05000(hisD)
PANSFCN45_18875(hisD) FCN45_18905(hisD)
VHAVIBHAR_02554
VCAM892_00680(hisD)
VAGN646_3369
VOWA9237_15570
VEJVEJY3_22851
VNIVIBNI_A1932 VIBNI_B0231
VCYIX92_08770
VNLD3H41_23030(hisD)
VKABTD91_14780(hisD)
VGIMID13_18425(hisD)
PGHFH974_23985(hisD)
GHOAL542_00750(hisD) AL542_03485(hisD)
PMUIG4G71_12360(hisD)
PFEPSF113_0825
PFSPFLU_1949
PALKPSAKL28_22220
PEZHWQ56_11980(hisD)
PSYCDABAL43B_1044(hisD1)
ABKLX00_09300
ABAUIX87_19995
COLWA3Q33_05355
THTE2K93_07265(hisD)
THAPFNC98_06420(hisD)
PARTPARC_a1302(hpsN)
PAGAPAGA_a2523(hpsN)
AMACMASE_15385
AMBAMBAS45_15845
ALRDS731_00845(hisD)
GAGGlaag_2410
GPSC427_0082
PMESFX988_00704
SPIUSPICUR_05125
GAIIMCC3135_20750(hpsN_1) IMCC3135_26035(hpsN_2) IMCC3135_30885(hpsN_3)
HHUAR456_20185 AR456_20195
HCOLOKO_03376(hpsN)
HHHCLM76_02795(hisD)
HBEBEI_0845(hpsN1) BEI_1107(hpsN2)
HAFC8233_03385(hisD)
HCAMI4484_05145(hisD) I4484_16810(hisD)
HSXHNO51_16710(hisD)
KUYFY550_15220(hisD)
PAURFGL86_17225(hisD)
MMEMarme_3106
NJPNEJAP_0151 NEJAP_1559
LLPGH975_08280(hisD)
SALNSALB1_1666
TSNW908_00390 W908_01090
THINCRN91_00450(hisD) CRN91_00980(hisD)
REHH16_A1694(h16_A1694)
CUHBJN34_08955
REUReut_C6092
CPAUEHF44_26110(hisD)
CCAMM5D45_06840(hisD)
BCMBcenmc03_6970
BCHBcen2424_6312
BGOBM43_40(hisD)
BYIBYI23_C004140 BYI23_C004280
BUEBRPE67_CCDS07870(hisD) BRPE67_CCDS08060(hisD)
BGPBGL_2c18430(hisD)
BXEBxe_C0309
BXBDR64_8125(hisD)
BPHBphy_7422
PCAFDSC91_002433 DSC91_007274 DSC91_007675
PMEGFNZ07_08965(hisD)
PTROG5S35_25415(hisD)
PGISI6I06_21520(hisD)
PEWKZJ38_23565(hisD)
PANIDCO16_09170(hisD)
PTXABW99_14130
BUOBRPE64_BCDS07370
BHZACR54_00804(hpsN)
BTRMSAMEA390648700451(hisD_1)
BBROBAU06_19845
BFZBAU07_03250
AXYAXYL_01399(hisD2)
AISBUW96_19425
ASWCVS48_08695(hisD)
AKATKWG_18855 TKWG_25569
AMIMMIM_c09530(hisD2)
PARKLSG25_14785(hisD)
AANTHUK68_04570(hisD)
VEIVeis_0769
ADNAlide_2313
ADKAlide2_2507
RTARta_27270(hisD)
LIHL63ED372_00902(hpsN)
HYNF9K07_28790(hisD)
HHFE2K99_23220(hisD)
XYKGT347_15510(hisD)
ACOMCEW83_08425(hisD)
AZRCJ010_08300(hisD)
BEBAEM42_10120
DFIAXF13_09680
DEOCAY53_05305
DATHRM2_03140(hisD1)
DALKDSCA_18210(hisD_1)
DEKDSLASN_21760(hisD_1) DSLASN_21880(hisD_2)
MLOmlr6649
MLNA9174_10755
MESWA9K65_021575
MESRFGU64_03150(hisD)
MESMeso_1928
AAKAA2016_6277
PHTBLM14_21300
RPODE0E05_11230(hisD)
NKIKW403_11225(hisD)
ORMHTY61_12010(hisD)
KMNHW532_13965(hisD)
SMDSmed_1713 Smed_4290
RHINGR_b04410 NGR_b16070(hisD1)
SFHSFHH103_01284(hisD2)
SIXBSY16_5513(hisD)
SAMESAMCFNEI73_pC1468(hisD)
SINOSS05631_c35480
EADOV14_b0880(hisD1)
EAKEKH55_3859
ARAArad_12308
RECRHECIAT_PC0000802
REIIE4771_PB00243(hisD-2)
RLEpRL80041(hisD2)
RHRCKA34_28430(hisD)
RGRFZ934_23660(hisD)
RRGJ3P73_36000(hisD)
SHZshn_14670 shn_29190
SOJK6301_19620(hisD)
VGOGJW-30_1_00907(hpsN_1) GJW-30_1_01965(hpsN_2)
BOSBSY19_1289(hisD)
BOFFQV39_18635(hisD)
XDIEZH22_20100(hisD)
SNOSnov_0212 Snov_2959
STARG3545_11255(hisD) G3545_24870(hisD)
LNEFZC33_00875(hisD) FZC33_14695(hisD)
APRAG3A50_21635(hisD)
APOLK9D25_00705(hisD) K9D25_08335(hisD) K9D25_16755(hisD) K9D25_22105(hisD)
MNOMnod_4267
MMESMMSR116_01585(hisD)
RHJHZY79_09725(hisD)
CHELAL346_12475
CDQBOQ54_05175
RHZRHPLAN_60230
DEIC4375_12335(hisD) C4375_12360(hisD)
DSALK1X15_00960(hisD) K1X15_00985(hisD)
HDIHDIA_3170(hpsN)
MMEDMame_04313(hpsN_1) Mame_05173(hpsN_2) Mame_05185(hpsN_3)
AUAM673_19035
AALAIGS74_17450(hisD)
AALMLUX29_19515(hisD)
AUZSa4125_17400(hisD_2)
AUBLXB15_15350(hisD)
BRND1F64_19415(hisD)
PSINCAK95_16175
LABRCHH27_12040(hisD) CHH27_16760(hisD)
LABPFJ695_27790(hisD)
LABTFIU93_30275(hpsN1) FIU93_30335(hpsN2)
LAGGB0E33_28460 B0E33_28515
CFHC1707_01990(hisD)
SILSPO0594(hpsN) SPO0981
RUAD1823_05095(hisD) D1823_18835(hisD)
RUTFIU92_07910(hpsN1) FIU92_18225(hpsN2)
JANJann_1104 Jann_1398
RDERD1_3808(hisD) RD1_3948(hisD)
RLIRLO149_c004880(hisD2) RLO149_c006370(hisD3)
RPONG3256_03870(hisD) G3256_13775(hisD)
DSHDshi_2034(hisD2) Dshi_2242(hisD3)
PGAPGA1_c07750(hisD1) PGA1_c25490(hisD2) PGA1_c27370(hisD3)
PGLPGA2_c07530(hisD2) PGA2_c25390(hisD3)
PGDGal_00689 Gal_02716
PHPPhaeoP97_01086(hisD3)
PPICPhaeoP14_00696(hisD1) PhaeoP14_02480(hisD3)
PHQD1820_08400(hisD) D1820_16950(hisD)
OATOAN307_c35180(hisD2) OAN307_c48490(hisD3)
OAROA238_160p0290(hisD) OA238_c24160(hisD1) OA238_c29640(hisD2) OA238_c48370(hisD4)
OTMOSB_32490(hpsN)
OCTFTO60_12465(hisD) FTO60_13760(hisD)
LMDMETH_14695 METH_22265
LEJETW24_02325(hisD) ETW24_15625(hisD)
LAQUR2C4_00650(hisD) R2C4_03535(hisD)
LEVETW23_01060(hisD) ETW23_14945(hisD) ETW23_15430(hisD)
REDroselon_00226
MALGMALG_00809 MALG_01230 MALG_04086 MALG_05015
YPACCEW88_04375(hisD) CEW88_22695(hisD)
YANAYJ57_15325
TPROGa0080559_TMP3736 Ga0080559_TMP4849
SUAMBOO69_14470
SULZC1J03_04920(hisD) C1J03_11915(hisD)
SULIC1J05_06910(hisD) C1J05_16090(hisD)
SULDB5M07_10355 B5M07_10390
SPOTG6548_16730(hisD)
SMEDJNX03_07090(hisD) JNX03_12640(hisD) JNX03_17100(hisD) JNX03_17125(hisD)
SINLDSM14862_01599(hpsN)
SPSESULPSESMR1_02323(hpsN) SULPSESMR1_02367(hpsN)
TOMBWR18_03280
RMMROSMUCSMR3_00082(hpsN) ROSMUCSMR3_02361(hpsN)
ROKRAK1035_0822 RAK1035_2931
RIDRIdsm_00494(hpsN)
ROMEI983_02800(hisD) EI983_18900(hisD)
ROHFIU89_02610(hpsN1) FIU89_13955(hpsN2)
AHTANTHELSMS3_04524 ANTHELSMS3_04949
SAGUCDO87_14620(hisD) CDO87_18475(hisD) CDO87_18520(hisD)
THAACFI11_07280(hisD) CFI11_22175(hisD)
MARUFIU81_03585(hpsN)
ROTFIV09_00080(hpsN)
MALUKU6B_37700(hisD_1) KU6B_37810(hisD_2) KU6B_40350(hisD_3)
HATRC74_10990
LSALKBK07_04225(hisD)
PDEPden_1091 Pden_3579
PAMIJCM7686_1850
PYEA6J80_16310(hisD) A6J80_16410(hisD)
PZHCX676_13155(hisD) CX676_13200(hisD)
PAROCUV01_13375(hisD) CUV01_13420(hisD)
PARUCYR75_12595(hisD)
PPANESD82_00940(hisD) ESD82_16450(hisD)
PTPRCA23_c21930(hisD2) RCA23_c26870(hisD3)
RSUNHU_04453(hisD)
THWBMG03_09575
RBGBG454_15370(hisD)
GEHHYN69_00370(hisD)
TAWEI545_04905(hisD) EI545_04925(hisD) EI545_14725(hisD)
SEDIEBB79_03180(hisD) EBB79_14275(hisD)
BOOE2K80_12245(hisD) E2K80_12270(hisD)
PSEBEOK75_01145(hisD) EOK75_18460(hisD)
PAEDG5B38_17045(hisD)
POZI0K15_18095(hisD) I0K15_20480(hisD)
PPAFI8N54_04660(hisD)
CACTHZ995_04845(hisD) HZ995_10075(hisD) HZ995_11300(hisD)
THASC6Y53_06700(hisD)
GCEKYE46_06510(hisD) KYE46_13960(hisD) KYE46_15045(hisD)
FAQG5B39_15400(hisD)
AMAQGO499_11575(hisD)
HBCAEM38_03115
NARSaro_3423
NPPPP1Y_Mpl6151
NREBES08_18880 BES08_18910
NOVTQ38_020025(hisD)
NOTC7W88_17740(hisD)
NORFA702_20075(hisD) FA702_20105(hisD)
NOGGKE62_07885(hisD) GKE62_11150(hisD)
NDRHT578_09325(hisD)
RDICMV14_09780(hisD)
SPHITS85_23210
SSUAFPZ54_13510(hisD)
SBINSBA_ch2_1600(hisD)
SPHRBSY17_83(hisD)
SPPHKFK14_22710(hisD)
BLASBSY18_3965(hisD)
BFWB5J99_00910
SPHJBSL82_11015
PALGHFP57_16015(hisD)
SANDH3309_03500(hisD)
POQKZX46_14060(hisD)
RMTIAI58_21565(hisD)
SRFLHU95_15400(hisD)
SHUMSTHU_10300(hisD_1)
SVCSTVA_44230(hisD_2)
NAOY958_19140(hisD)
NCBC0V82_13695(hisD)
HTQFRZ44_36780(hisD1) FRZ44_43920(hisD)
HADHFRZ61_35830(hisD1) FRZ61_41810(hisD)
THACCSC3H3_22895(hisD)
PUBSAR11_0801(hisD2)
PEGE5R92_01975(hisD)
APMHIMB5_00003860
APBSAR116_0046 SAR116_2138
BMDBMD_1657(hisD)
BMEGBG04_3973(hisD)
BEOBEH_11410
BCLABC1168
BONA361_25265
BKOCKF48_05215(hisD)
CFIRNAF01_23295(hisD)
GSRGS3922_14545
LYGC1N55_20065(hisD)
LMACI6G82_22305(hisD)
LYCFH508_0017105(hisD)
VIRX953_15495
BMURABE28_019205
PASABAOM_4816(hpsN)
PSYHD0S48_10150(hisD)
RUEDT065_17120(hisD)
SALEEPH95_03675(hisD)
SCIBHUG20_05105(hisD)
SCIAHUG15_07010(hisD)
MSEMGMB29_06560(hisD)
STEAC0679_01115(hisD)
SEQOSE1039_24510
SSCUCEP64_13375(hisD)
BCHSJNE38_27525(hisD)
PPSCEHS13_22085(hisD)
AACOK1I37_06045(hisD)
BTSBtus_2894
PLNPlano_2203
PKUAUO94_04670
PRTAUC31_07070
PLLI858_011830
PMARB0X71_17400
PPLABBI15_14945
PFAEAJGP001_12870
PLXCW734_04305(hisD)
SPSYAZE41_01200
SPORSporoP33_08725
SPOPSporoP37_09120
SURESporoP32a_00250
RSTATY39_08710
CACECACET_c12870(hisD1)
CRSFQB35_14815(hisD)
BYLA4V09_16190
BLAUDQQ01_02240(hisD)
BPROPMF13cell1_01234(hpsN) PMF13cell1_01786(hisD)
PDCCDIF630_01753(hisD)
CDCCD196_1504(hisD)
CDLCDR20291_1479(hisD)
PDFCD630DERM_15820(hisD)
FWADCMF_09405 DCMF_20190
TEPTepRe1_1016
TAETepiRe1_1115(hisD)
NTHNther_1898
MGOAFA91_12390 AFA91_19790 AFA91_28975
MDXBTO20_06200 BTO20_27735
MGROFZ046_01425(hisD)
MSENK3U95_23775(hisD)
MSMMSMEG_2012(hisD) MSMEG_5656(hisD)
MSGMSMEI_1967 MSMEI_5507
MSBLJ00_10040 LJ00_27970
MSNLI99_10040 LI99_27975
MSHLI98_10040 LI98_27980
MVQMYVA_3092(hisD2)
MLLB1R94_00320
MAUUNCTC10437_01640(hpsN)
MTYMTOK_36470(hisD_1)
MARZMARA_23200(hisD_2) MARA_40130(hisD_3)
MPOFMPOR_51220(hisD_2)
MMATMMAGJ_22130(hisD_1)
MSEIMSEDJ_11570(hisD_1) MSEDJ_59590(hisD_3)
CGTcgR_0116
CGSC624_00560
CGGC629_00560
CGYCGLY_10805(hisD1) CGLY_10865(hpsN)
CCJZccrud_10815 ccrud_10880
RHARHA1_ro04557(hisD2)
ROPROP_44710(hisD)
ROAPd630_LPD01008 Pd630_LPD03671
RHODAOT96_06360
RKOJWS14_19480(hisD) JWS14_24755(hisD)
SCBSCAB_89041(hisD)
SMALSMALA_1386
SSOII1A49_10450(hisD)
SCXAS200_01765
SGMGCM10017557_79280(hisD)
SAUOBV401_10775
SGEDWG14_02657(hpsN)
SASTCD934_07485(hisD) CD934_07505(hisD)
SDECL3078_40055(hisD)
MIMAKG07_13985 AKG07_14015
MLVCVS47_01021(hpsN_1) CVS47_01027(hpsN_2)
CUBBJK06_11385
PLAPEAO79_05850(hisD)
LVIG7068_07535(hisD)
LINSG7067_01020(hisD)
AGGC1N71_13130(hisD)
ARUASPU41_01785
ARQBWQ92_09300
ARTHC3B78_17490(hisD)
PSEYGU243_21335(hisD)
NMESH9L09_09850(hisD)
AEBC6I20_02945(hisD)
ACTWF7P10_23120(hisD) F7P10_23160(hisD)
KRAKrad_2498
SENSACE_3119(hisD2)
AMYCCU254_18835(hisD) CU254_18870(hisD)
AMYYYIM_21405(hpsN1) YIM_21450(hpsN2)
PSEAWY02_28305
PSEEFRP1_14415 FRP1_14450
PSEHXF36_14660 XF36_14695
PSEQAD006_22080 AD006_22115
PECQAD017_01665 AD017_01700
PHHAFB00_23140
PBROHOP40_22260(hisD)
PMADBAY61_21005
CATICS0771_63050(hisD_1)
DVCDvina_39095(hisD)
BSOLFSW04_24235(hisD)
CWOCwoe_0128
SBAEDSM104329_04999(hpsN)
MRBMrub_2545
MREK649_09815
LPAVPLANPX_2467
PLHVT85_11070(hpsN)
SACISinac_7380
PBORBSF38_01252(hpsN)
AGVOJF2_30990(hpsN)
TAITaci_0033
CPORBED41_01700
PVFJ5A55_01930
NIAA8C56_13465
FGGFSB75_00075(hisD)
PGINFRZ67_05840(hisD)
MMABHQ865_23750(hisD)
RHOZGXP67_01645(hisD)
RSIRunsl_0478
RUNDR864_23085(hisD)
RUPDTQ70_06245(hisD)
EOLEmtol_0096
HYJFHG12_20705(hisD)
HMTMTP16_23690(hisD)
HDLHALDL1_10300
HALJG9465_23315(hisD)
NHOHWV23_09090(hisD)
HALIBV210_13745
HAERDU502_08815(hisD)
HALUHUG12_14850(hisD)
NVRFEJ81_21100(hisD)
NAYHYG81_22685(hisD)
NOUNatoc_2917
 » show all
Reference
1  [PMID:20150239]
  Authors
Mayer J, Huhn T, Habeck M, Denger K, Hollemeyer K, Cook AM
  Title
2,3-Dihydroxypropane-1-sulfonate degraded by Cupriavidus pinatubonensis JMP134: purification of dihydroxypropanesulfonate 3-dehydrogenase.
  Journal
Microbiology 156:1556-64 (2010)
DOI:10.1099/mic.0.037580-0
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.308
IUBMB Enzyme Nomenclature: 1.1.1.308
ExPASy - ENZYME nomenclature database: 1.1.1.308
BRENDA, the Enzyme Database: 1.1.1.308

DBGET integrated database retrieval system