KEGG ENZYME: 1.1.1.327

ENZYME: 1.1.1.327

Entry

EC 1.1.1.327 Enzyme

Name

5-exo-hydroxycamphor dehydrogenase;
F-dehydrogenase;
FdeH

Class

Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor

Sysname

5-exo-hydroxycamphor:NAD+ oxidoreductase

Reaction(IUBMB)

5-exo-hydroxycamphor + NAD+ = bornane-2,5-dione + NADH + H+ [RN:R10021]

Reaction(KEGG)

R10021

Substrate

5-exo-hydroxycamphor [CPD:C03448];
NAD+ [CPD:C00003]

Product

bornane-2,5-dione;
NADH [CPD:C00004];
H+ [CPD:C00080]

Comment

Contains Zn2+. Isolated from Pseudomonas putida, and involved in degradation of (+)-camphor.

History

EC 1.1.1.327 created 2012

Orthology

K19649

5-exo-hydroxycamphor dehydrogenase

Reference

1 [PMID:4351810]

Authors

Rheinwald JG, Chakrabarty AM, Gunsalus IC

Title

A transmissible plasmid controlling camphor oxidation in Pseudomonas putida.

Journal

Proc Natl Acad Sci U S A 70:885-9 (1973)
DOI:10.1073/pnas.70.3.885

Reference

2 [PMID:2613690]

Authors

Koga H, Yamaguchi E, Matsunaga K, Aramaki H, Horiuchi T

Title

Cloning and nucleotide sequences of NADH-putidaredoxin reductase gene (camA) and putidaredoxin gene (camB) involved in cytochrome P-450cam hydroxylase of Pseudomonas putida.

Journal

J Biochem 106:831-6 (1989)
DOI:10.1093/oxfordjournals.jbchem.a122939

Reference

3 [PMID:8334169]

Authors

Aramaki H, Koga H, Sagara Y, Hosoi M, Horiuchi T

Title

Complete nucleotide sequence of the 5-exo-hydroxycamphor dehydrogenase gene on the CAM plasmid of Pseudomonas putida (ATCC 17453).

Journal

Biochim Biophys Acta 1174:91-4 (1993)
DOI:10.1016/0167-4781(93)90098-X

Sequence

[ag:BAA03511]

Other DBs

ExplorEnz - The Enzyme Database:

1.1.1.327

IUBMB Enzyme Nomenclature:

1.1.1.327

ExPASy - ENZYME nomenclature database:

1.1.1.327

UM-BBD (Biocatalysis/Biodegradation Database):

1.1.1.327

BRENDA, the Enzyme Database:

1.1.1.327

DBGET integrated database retrieval system