KEGG   ENZYME: 1.1.1.335
Entry
EC 1.1.1.335                Enzyme                                 
Name
UDP-N-acetyl-2-amino-2-deoxyglucuronate dehydrogenase;
WlbA;
WbpB
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
UDP-N-acetyl-2-amino-2-deoxy-alpha-D-glucuronate:NAD+ 3-oxidoreductase
Reaction(IUBMB)
UDP-N-acetyl-2-amino-2-deoxy-alpha-D-glucuronate + NAD+ = UDP-2-acetamido-2-deoxy-alpha-D-ribo-hex-3-uluronate + NADH + H+ [RN:R10140]
Reaction(KEGG)
R10140
Substrate
UDP-N-acetyl-2-amino-2-deoxy-alpha-D-glucuronate [CPD:C04573];
NAD+ [CPD:C00003]
Product
UDP-2-acetamido-2-deoxy-alpha-D-ribo-hex-3-uluronate [CPD:C20395];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
This enzyme participates in the biosynthetic pathway for UDP-alpha-D-ManNAc3NAcA (UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-mannuronic acid), an important precursor of B-band lipopolysaccharide. The enzymes from Pseudomonas aeruginosa serotype O5 and Thermus thermophilus form a complex with the the enzyme catalysing the next step the pathway (EC 2.6.1.98, UDP-2-acetamido-2-deoxy-ribo-hexuluronate aminotransferase). The enzyme also possesses an EC 1.1.99.2 (L-2-hydroxyglutarate dehydrogenase) activity, and utilizes the 2-oxoglutarate produced by EC 2.6.1.98 to regenerate the tightly bound NAD+. The enzymes from Bordetella pertussis and Chromobacterium violaceum do not bind NAD+ as tightly and do not require 2-oxoglutarate to function.
History
EC 1.1.1.335 created 2012
Pathway
ec00520  Amino sugar and nucleotide sugar metabolism
ec00541  O-Antigen nucleotide sugar biosynthesis
ec01100  Metabolic pathways
Orthology
K13016  UDP-N-acetyl-2-amino-2-deoxyglucuronate dehydrogenase
K13020  UDP-N-acetyl-2-amino-2-deoxyglucuronate dehydrogenase
Genes
CBRAA6J81_14380
CWECO701_19350
CAMAF384_24285
CFARCI104_22315
CTELGBC03_07515
KASKATP_40590
BUFD8682_19095
BAGEBADSM9389_06600
BFTMNO13_03405
SMAFD781_0082
RAHRahaq_1175
RACEJHW33_00230
RAQRahaq2_1252
RAAQ7S_05670
ROXBV494_01215
RVCJ9880_13720
SODSant_2703
PAOPat9b_4259
PLUplu4797(wblB)
PLUMA4R40_23860
PAYPAU_04312(wblB)
PTTVY86_07520
PLUICE143_24590
XBOXBJ1_4314
XNEXNC1_0112
XNMXNC2_0114
PVCG3341_19065
HPARAL518_10040
LRINCTC12151_03551(gfo)
MSUMS1500(mviM)
BSUNA4G13_04960
ASUAsuc_0110
AAZADJ80_05775
AVTNCTC3438_01791(gfo_2)
DJICH75_07775
DJAHY57_11970
DYEEO087_12210
DCSISN74_19545
DTLH8F01_18615
VTUIX91_00690
VEUIXK98_09355
PAEPA3158(wbpB)
PAEVN297_3269(wbpB)
PAEIN296_3269(wbpB)
PAEMU769_09132
PAECM802_3267(wbpB)
PAEOM801_3134(wbpB)
PMYPmen_1858
PPUHB479_06900
PAZOAYR47_15420
PBAPSEBR_a1558
PDRH681_23225
PSESPSCI_2866
PSOSPOS17_4987
PSETTHL1_1977
PXAKSS93_10395(wbpB)
PANHHU763_007130(wbpB)
PCAVD3880_03190
MSRAU15_01125
MARIACP86_02340
MARAD0851_05440
MARJMARI_04640(wbpB)
PCRPcryo_0614
PRWPsycPRwf_0247
PALIA3K91_0139 A3K91_0719
PSYPE5677_09790 E5677_12790
ACBA1S_0053
ABKLX00_00465
ABWBL01_01445
ACCBDGL_002972
ACDAOLE_19130
AIDCTZ23_14935
ADSFPL17_13950
ACHICDG60_01075
ASHAG8E00_00505
SAZSama_2259
SSESsed_2972
SSEMJYB85_11890
SGLAFJ709_05395
SVMKDH10_000086
IPICEW91_09915
IDICWC33_02945
PSEOOM33_04950
PLZS4054249_18600
PPISB1L02_14600
PXIJ5O05_07160
PVBJ5X90_03255 J5X90_03345
PSAZPA25_03820(wbpB)
AALEP13_13975
AAUSEP12_05245
ASPAOR13_496
ASQAVL57_16025
AAWAVL56_14960
ALEAV939_14935
ALZAV940_14685
LALAT746_12775
CATEC2869_02600 C2869_15620
PAEWKIH87_04760
CELLCBR65_17455
SDESde_0872
AFUSEYZ66_11590
LFALFA_0788
LOKLoa_02107
LWASAMEA4504053_1071(gfo)
LSSNCTC12082_00067(gfo)
MBUREQU24_04405
FRXF7310_06790
CYYCPC19_11160
TANIJ8380_09335
TMBThimo_0036
THIMKFB96_04800
TNITVNIR_0687(pht4_[H])
TTITHITH_05750
SPIZGJ672_09095
HAHEENC22_10775
HCOLOKO_02148(wbpB)
HALOBWR19_11915
HTTHZS52_20505
HCAMI4484_08290 I4484_11335
HPIZGYM47_15080
HSXHNO51_07700 HNO51_11040
HSVHNO53_09795
HTXEKK97_08735 EKK97_12330
ADIB5T_01708(wbpB)
MMWMmwyl1_0822
MPRIMP3633_3247
MFOIJSY38_06740
TORR615_06290
MGEOCFI10_13645
OMEOLMES_5515
SUTRL0B52_04095
ORBIPMB12_01885
SDFACG33_04725
SEDSAAY24_11380
THINCRN91_03260
NELNELON_10585
NSIA6J88_04690
NMJNM96_12900
NEIBG910_03000
NEKCGZ77_00960
NZLD0T92_00375
NZOSAMEA4504057_0083(iolG)
NANINCTC12227_01671(gfo)
NBCH3L91_10800
NMUSH7A79_1726
NSCJ7445_11470
NDNH3L92_00305
NDULVJ88_11205
NMBMON40_05915
VFFVITFI_CDS0485
VITADP71_03400
VSTLVJ81_10700
VMSLVJ82_06285
NBACUN60_03460 CUN60_12660
PTESJQU52_03225
MCERMON37_00925
CVICV_4127
CVCBKX93_16815
CHROCXB49_18575
CHRIDK842_10875
CHRBDK843_16310
CRZD1345_02465
CHRMFYK34_19605
CHAECH06BL_04730(wlbA) CH06BL_39690(wlbA)
LHKLHK_02805(wblB)
PSENH8B_0413
AMAHDLM_4446
AQSDKK66_05305
VOGLCH97_14395
RPJN234_28855
REHH16_B0033(wbpB)
CUUBKK79_06660
COXE0W60_06205
PPNODA70_17270
LMIRNCTC12852_00294(afr_1)
CARIFNU76_04840
BPEBP0093(bplA)
BPCBPTD_0089(bplA)
BPERBN118_0162(wlbA)
BPETB1917_0096(bplA)
BPEUQ425_2060(bplA)
BPARBN117_0153(wlbA)
BPABPP0155(bplA)
BBHBN112_3256(wlbA)
BBRBB0155(bplA)
BBMBN115_0144(wlbA)
BBXBBS798_0154(bplA)
BPTBpet4814(wlbA)
BAVBAV0098(wlbA)
BHOD560_1328
BHMD558_1317
BHZACR54_00110(gfo)
BTRMSAMEA390648701342(bplA)
BPDZBBN53_20140
AXYAXYL_06286
AXNAX27061_5896
AXXERS451415_06023(gfo)
AISBUW96_24710
ASWCVS48_07140
TEQTEQUI_1006
TEAKUI_0407
TEGKUK_0147
AAMMFE795_15360
ODIODI_R2826
OUEI6G29_01505
PNAPnap_3129
POSDT070_03600 DT070_14460
POOF7R28_05840 F7R28_16145
AAVAave_0950
AJSAjs_3015
ACKC380_07385
ACIPCBP36_03010
ACISCBP35_15930
AMONH9L24_09495
DLAI6G47_27630
VAPVapar_1927
VPEVarpa_4688
VPDVAPA_1c53890
CTESO987_08010
CSERCCO03_06555
COFFOZ74_09545
HYBQ5W_21470
HYLLPB072_07145 LPB072_22690
KIAG8A07_07045
RGERGE_41570(bplA)
RBNRBXJA2T_06710
RDPRD2015_4065
MIUABE85_17725
SNNEWH46_01090
IDCLRM40_05260
ATERMW290_27430
HSEHsero_4195
HSZACP92_20960
HFRG5S34_02285
MASWAM586_10905
MASSCR152_27235
MANCIV454_20540
MFYHH212_25110
NOKFAY22_12115
LCHLcho_0289
PKTAT984_02045
RGUA4W93_23595
TTWLCC91_03250
BBAYA4V04_01330
APPCAP2UW1_0065
HEOC694_03500
HPJjhp_0620
HPAHPAG1_0661
HPSHPSH_03470
HHPHPSH112_03620
HHQHPSH169_03465
HHRHPSH417_03260
HPGHPG27_637
HPPHPP12_0690(wbpB)
HPBHELPY_0692
HPLHPB8_881(wbpB)
HPCHPPC_03400
HCAHPPC18_03315
HPMHPSJM_03455
HPEHPELS_03135
HPOHMPREF4655_20921
HPIhp908_0688(wbpB)
HPQhp2017_0665(wbpB)
HPWhp2018_0666(wbpB)
HPUHPCU_03650
HEFHPF16_0688(wbpB)
HPFHPF30_0654(wbpB)
HEQHPF32_0643(wbpB)
HEXHPF57_0700(wbpB)
HPTHPSAT_03405
HPZHPKB_0669
HPVHPV225_0684
HPXHMPREF0462_0737
HENHPSNT_03505
HPHHPLT_03380
HEGHPGAM_03495
HPNHPIN_03255
HEPHPPN120_03320
HEUHPPN135_03335
HESHPSA_03225
HPYSHPSA20_0708
HCNHPB14_03300
HPDKHP_0646(wbpB)
HEYMWE_0830(wbpB)
HERC695_03505
HEIC730_03505
HPYAHPAKL117_03210
HPYKHPAKL86_04340
HPYOHPOK113_0689(wbpB)
HPYLHPOK310_0668(wbpB)
HPYBHPOKI102_03625
HPYCHPOKI112_03660
HPYDHPOKI128_03220
HPYEHPOKI154_03450
HPYFHPOKI422_03630
HPYGHPOKI673_03435
HPYHHPOKI828_03435
HPYJHPOKI898_03630
HPYRK747_07485
HPYIK750_05685
HPYUK751_03995
HPYMK749_02110
HEMK748_00585
HEBU063_0983
HEZU064_0987
HHEHH_1662(wbpB)
HACHac_0861(wbpB)
HMSHMU06630
HFEHFELIS_04170
HBIHBZC1_15200
HCEHCW_05405
HCMHCD_05220
HCPHCN_0856(wbpB)
HCBHCBAA847_1124(wbpB)
HHMBN341_16330
HADCDV25_01305 CDV25_01335
HETBBW65_01175
HCLNCTC13205_00267(ycjS)
HWIA0Z60_07530
HSHNHP194022_04680
WSUWS2188(WBPB)
TDNSuden_1422
SULGFJR48_03715
SPALFM071_05905
CCOCCC13826_0542
CBLACBLAS_0711
ABUAbu_0662
ALANALANTH_0830
ANTArnit_2570
AAQIAAQM_2034
ASUIASUIS_2001
PACOAACT_0950
AHSAHALO_0814
HBVABIV_0864
SUNSUN_0093
SINUIMZ28_10360
GEBGM18_1433
GLOGlov_1510
GSBGSUB_15340
GERKP004_12105
GNTKP003_11600 KP003_17840
GPLM1B72_07915
PEFA7E78_01465
LIPLIC097
LIRLAW_30095
DBADbac_3255
DEOCAY53_06145
DOLDole_1819
DALDalk_1674
BSEDDN745_14955
PCAYFRD00_13475
BBAEFRD01_13735
NAFGQ61_06800
MESPC1M53_04250
MESMeso_4484
NIYFQ775_09675
PMOBHG718_00085
SMKSinme_4777
SMQSinmeB_3736
SMXSM11_pD0667
SMIBN406_05730
SMEGC770_GR4pD0650
SMELSM2011_b21355
SMERDU99_28765
SMDSmed_4750
SAMESAMCFNEI73_pC1037
SINOSS05631_b57670
EMXFKV68_31770
AGCBSY240_4564
AROB0909_16745
REPIE4803_CH00778
RGARGR602_CH03041
RHKKim5_CH00859
NGGRG540_PA12740
NENNCHU2750_04910
RHTNT26_2973
RFVRFYW14_03055
BJUBJ6T_32920
BJPRN69_15965
BRSS23_22680
BICLMTR13_10760
BRKCWS35_31765 CWS35_31850
BGQX265_13695
BGZXH91_11630
BBETF8237_26405
BARHWN72_33195
BELBE61_40460
BSEPHAP48_0047530 HAP48_0047655
BQBJ4P68_0000015 J4P68_0006710 J4P68_0006830
ANCGBB76_09925
HNIW911_00400
DEQXM25_13460
DEAFPZ08_13280
YTIFNA67_17200
PSFPSE_p0069
RUAD1823_06620
RUTFIU92_10720(pht2)
RPONG3256_01625
KVLKVU_PA0205
KVUEIO_3032
OTMOSB_21250(gfo_3)
SULIC1J05_06025
SPOTG6548_17115
TOMBWR18_15515
OCDFHY55_10395
HATRC74_13180
PAROCUV01_03365
PTPRCA23_c02930
THWBMG03_04755
PALWPSAL_034710(apsD_1)
FAQG5B39_12330
SPHKSKP52_10585
SPHQBWQ93_05585
SPHOC3E99_07010
SPLMBXU08_19465
SSING7078_06195
SPHLLPB140_06435
SPHSETR14_12065
ERRDVR09_11395
EBLAJGUZn3_12530(iolG_2)
AZMDM194_14155
MAGamb0131
MGRYMSR1_31310(ycjS_1)
MAGXXM1_0970
DVNHQ394_13385
THAIIT893_15695
MAGQMGMAQ_3670
MGMMmc1_2424
PEGE5R92_03420
APCHIMB59_00015070
APMHIMB5_00011140
BBATBdt_1672
BBACEP01_04555
BDCDOE51_07880
SBFJCM31447_25090
BLIBL03076
BLDBLi00809(yrbE)
BLHBaLi_c09130(yrbE)
BSONS101395_01005(bvdR)
BIFN288_23270
BMETBMMGA3_15120
BGYBGLY_0828
BWHA9C19_10500
BSAFBSL056_02015
BFDNCTC4823_03739(gfo)
BDAFSZ17_21485
BACIB1NLA3E_20885
BACWQR42_02065
BACQDOE78_22820
BCOHBC6307_01160
BCIRC2I06_01615 C2I06_02230 C2I06_13815
BEOBEH_14640
BCLABC0605
BLEBleG1_2898
BONA361_24880
CSUAIM538_21385
CFIRNAF01_22650
CSOALIS82_24415
OCNCUC15_17145
OCBCV093_18425
GKAGK3166
GTEGTCCBUS3UF5_35350
GTKGT3570_15455
GTMGT3921_03250
BCALCWI35_12090
GYCGYMC61_3257
GYAGYMC52_3288
GCTGC56T3_3177
GGHGHH_c32410
GELIB49_07995
GSEGT50_07690
GEJA0V43_13695
GZAIC807_11900
PTBDER53_03275
AAMYGFC30_481
AXLAXY_03830
LYGC1N55_07270
HHDHBHAL_2426
VIGBKP57_04850
VILCFK37_01455 CFK37_01460
VNECFK40_17645
VPTKBP50_03840
FARABE41_017785
BMURABE28_003935
PSYHD0S48_07970
PSYOPB01_04620
GRCGI584_05185 GI584_07220 GI584_18230
POFGS400_13830
MEKUHUW50_20990
AIAAWH56_015925
BLENNCTC4824_00366(yvaA_1) NCTC4824_00367(ycjS_1) NCTC4824_01177(ycjS_5)
SEDDERJ70_04170 ERJ70_06670
BVQFHE72_22055
BVJI5776_14050
BOUI5818_17210
GAJMY490_11980
SSPSSP1334
SXYBE24_04425
SXLSXYLSMQ121_1372
SXOSXYL_01457
SEQOSE1039_12560 SE1039_12570
SCOHBZ166_11260
SNLBJD96_07230
SPSDJMB28_07585
PJDPjdr2_4073 Pjdr2_5204
GYMGYMC10_1211
PLVERIC2_c20090
PGMPGRAT_15295
PODPODO_28500
PAENP40081_17815
PAEFR50345_14270
PAEQR50912_16610
PAEAR70723_15265
PAEER70331_24850
PAEHH70357_16925
PAEJH70737_13620 H70737_15725
PBJVN24_11935 VN24_16770
PIHUB51_13970
PSONJI735_24145
PNPIJ22_38360 IJ22_49060
POWIJ21_32520 IJ21_43900
PXLBS614_28655
PYGAWM70_20130
PDHB9T62_11895
PIBBBD41_08725
PCXLPB68_18930
PVOPVOR_08105
PLWD5F53_23505
PPSCEHS13_28630
PLUTEI981_18335 EI981_27145
PALBEJC50_27535 EJC50_29195
PCHIPC41400_04320
PBKBack11_15410 Back11_63550
PRZGZH47_11580 GZH47_17545 GZH47_31940
PLYCGXP70_05125 GXP70_06580 GXP70_28940
TCOTheco_3205
ANXACH33_01670
ATHEK3F53_17345
PKUAUO94_04055
PMARB0X71_16965 B0X71_16970
NTRB0W44_04610
LFBC1X05_09310 C1X05_16015
TVUAB849_005520
KPULGXN76_15355
KEBGXN75_16715
PABSJIR001_23250 JIR001_30150
SPABKQ224_02975
ECASECBG_00089
VCPH9L18_01905
AUIAPT62_02650 APT62_02655
AUHAWM75_03250
CRNCAR_c21330
JEHEJN90_03895
JARG7057_03175
JPOG7058_07610 G7058_08180
CTCCTC_02264
CTETBN906_02465
CNONT01CX_1781
CBACLB_3136
CBHCLC_3009
CBYCLM_3513
CBLCLK_2501
CBKCLL_A3174
CBBCLD_1433
CBICLJ_B3373
CBNCbC4_0993
CBTCLH_2923
CBFCLI_3166
CBMCBF_3155
CBJH04402_03184
CBECbei_4619
CBZCbs_4619
CBEILF65_05162
CKLCKL_3168
CKRCKR_2806
CLJCLJU_c34090
CSRCspa_c53470
CPASClopa_4712
CSBCLSA_c41240(yrbE2)
CAHCAETHG_1307
CSQCSCA_4789
CLDCLSPO_c32020
CCKCcar_17270
CBUTATN24_15725
CTYKCTK_C08660
CEUA7L45_12160
CTAEBGI42_12580
CARGRSJ17_08110
CDRKB9W14_20925
CDYF3K33_23515
CCOHSAMEA4530647_1933(ycjS)
CFERD4Z93_04405
CGASJ1C67_09890 J1C67_19005
CLOSDMR38_17085
CNNCNEO_4194
AMTAmet_3444
HHWNCTC503_02000(afr)
CALEFDN13_03435
CLOHMPREF0868_0599
FSAC5Q98_06705
RUKA4V00_10630
RBPB6259_08165
RHEREHE19_018995
CTHDCDO33_08210 CDO33_08265
CCELCCDG5_0711
FPLAA4U99_06465
EHAEthha_0671
FPRFP2_24960
FPRACG447_01245
FDUGXM22_07620
CAPREQM14_12870
OBJEIO64_14100
CAMLH6X83_09695
CLFGJQ69_02335
CFEMHCR03_17325
BPBbpr_I0406
BYLA4V09_01925 A4V09_19545
BPROPMF13cell1_01643(gfo_1) PMF13cell1_05065(iolX_4) PMF13cell1_05439(gfo_4)
CSHClosa_0342
ACELacsn021_15130
CSTCLOST_2336
ROCHF520_12270 HF520_12275
SWOSwol_0706
DDHDesde_3864
DDLDesdi_3236
DMTDESME_14510
SGYSgly_3009
DORDesor_5337
DAIDesaci_4448
DMIDesmer_4338
DEDDHBDCA_p2685
DECDCF50_p2696
DRSDEHRE_13250
TFRBR63_12295
ELMELI_2560
EMTCPZ25_005080
VGUHYG85_03210 HYG85_08055 HYG85_13860
VPYHZI73_04125 HZI73_21530 HZI73_24085
SAYTPY_3674
SAPSulac_3373
STHRBXT84_14985
MDVC5Q96_07730
EUUADJ67_02465
TITThit_0178
TMTTmath_0235
TKITKV_c06640(mviM)
CSCCsac_0599 Csac_1804
ATEAthe_1239 Athe_2334
COBCOB47_1317 COB47_2107
CHDCalhy_0192 Calhy_1486
COWCalow_1030 Calow_2063
CKICalkr_1220 Calkr_2363
CLCCalla_0086 Calla_0628
CKNCalkro_0219 Calkro_1461
CCHAELD05_07305 ELD05_12070
CDIACaldiYA01_01930 CaldiYA01_12690
TSHTsac_0498
MASMahau_0353 Mahau_1490
TEPTepRe1_1590
TAETepiRe1_1712
TOCToce_1590
HALSD7D81_05130
AARAcear_2129
HHLHalha_0117
FMAFMG_0585
APRApre_1597
SPOAEQM13_10605
PUFUFO1_0304
TSGHLK68_13225
LPILLIP_1016
TBMBK010_04830
TBZBK011_02340 BK011_09435
CGBcg2918
CGUWA5_2546
CGTcgR_2455 cgR_2540
CGSC624_12525 C624_12960
CGGC629_12530 C629_12965
CGMcgp_2918
CGJAR0_12795
CGQCGLAR1_12660
CGXSB89_12425
CGYCGLY_11570
CDOCDOO_09605
CUTCUTER_00580
CSTACSTAT_03290
CCJZccrud_11890
CAMGCAMM_03405
CSURN24_2630 N24_2719
CCYSSAMEA4530656_1528(gfo)
CCYCSCMU_39910
BFVC628_13055
RERRER_46960
REYO5Y_22175
REBXU06_22290
RQIC1M55_23630
ROPROP_15350
ROAPd630_LPD06020
RRZCS378_14825
RHODAOT96_03665
RKOJWS14_09505
RGOKYT97_30395
ROZCBI38_24870
SCIB446_01935 B446_33355
SALUDC74_7991
SALLSAZ_41245
STREGZL_p00135
SCXAS200_44420
SCADDN051_42370
SVNCP980_33425
SSEOD0Z67_01125
SMOBJ7W19_27470
LXXLxx17360(bplA)
LXYO159_19880
LEIFHF024_02130
LSEF1C12_00010
CMICMM_2271
CMSCMS2465
CMCCMN_02246
CMHVO01_10570
CCAPAES38_11080
MPRTET475_07805
MOYCVS54_03687(iolX)
CUMNI26_03705
CUBBJK06_03895
CUGC1N91_03560
FRPAX769_09535
AGFET445_08965
MSPOKXZ72_13600
HUWFPZ11_06520
GRYD7I44_03310
PLAPEAO79_04425
GLNF1C58_16425
ARTArth_0500 Arth_3483
ARRARUE_c04960
ARMART_1531
ARLAFL94_05080
AREAL755_16035
AAQAOC05_10420
ARWMB46_11180
ARHAHiyo8_29850 AHiyo8_52300
ARYATC04_12805
ARZAUT26_02220
ARQBWQ92_13480
ARNCGK93_02805 CGK93_19165
ARXARZXY2_3410
ARTHC3B78_03100
ARTPE5206_01110
ACITHPK19_06430
ARIUM93_15235
AAUAAur_0525
PUEFV140_02760
PNVJMY29_02410 JMY29_13015
ACHAchl_0779
APNAsphe3_06760
PSULAU252_07695 AU252_09955
PSNINIBR502771_01505
PSEYGU243_18880
GPRJQN66_05520
SATKSA2016_0412 SA2016_3913
BCVBcav_3315 Bcav_3348
BFABfae_01870
BRVCFK39_09080
BGGCFK41_16260
BRZCFK38_01740
BSAUDWV08_15020
BRRC1N80_02130
IVAIsova_2543
CCEUCBR64_12280
PSEIGCE65_04230
GEZFE251_10180
HALTIM660_02185 IM660_02195 IM660_11160
RHALLQF10_01950
MPHMLP_05720
MIKFOE78_01370
MICGGJV80_16690 GJV80_18860
RAINRai3103_13930
PRVG7070_05670 G7070_06850
MGGMPLG2_3178
SACEGIY23_12090
ACTNL083_1494 L083_6344
AFSAFR_16830
PLABC6361_08510
PLATC6W10_05080
ATLAthai_37850
DVCDvina_14965
CCAZCOUCH_19560
RUBGBA63_02070
CWOCwoe_4459
ELEElen_0638
SYNWSynWH8103_00503
PMIPMT9312_1300
PMBA9601_14101
NCNBZZ01_20160
RRSRoseRS_2681
RCARcas_2202
ABAOBEQ56_06830
KBSEPA93_43700
TTRTter_0217 Tter_1908
DPDDeipe_2030
DSWQR90_12655
DEINDAAJ005_05030
DRDLMT64_11840
TRATrad_1846
TTHTT_C0287(wbpB)
MRBMrub_0358
MREK649_01410
MTAIMtai_v1c25020
FGIOP10G_3931
OTEOter_0898
OBGVerru16b_02254(afr_3)
OBTOPIT5_15870 OPIT5_24765
CAACaka_2925
LUOHHL09_22720
VBAIMCC26134_03350
RBARB6199
PSLPsta_2822 Psta_3167
PIRVN12_21635(afr_4)
RULUC8_06010(wbpB_1) UC8_10100(gfo_3) UC8_50390(wbpB_2)
MFFMFFC18_27070(gfo_4)
ROLCA51_12660(gfo_3)
AHELQ31a_45900(ycjS_2)
LCREPla8534_38000(afr_6) Pla8534_38530(gfo_6) Pla8534_69440(wbpB)
AAGGETAA8_64750(afr_6)
BVOPan97_25430(gfo_5)
TTFTHTE_2673
LPAVPLANPX_2245
AMUCPan181_17760(afr_1)
PNDPla175_16240(ycjS)
AMOBHG15A2_31400(wbpB)
PLMPlim_2198
PEHSpb1_29720(afr_3)
PBSPlabr_1624 Plabr_2773
PLSVT03_19395(afr_3) VT03_23415(ycjS_2)
PLHVT85_17850(gfo_3)
FMRFuma_02244(iolG_9) Fuma_06237(afr_5)
GMRGmarT_05450(afr_1)
GIMF1728_03030 F1728_11525
GPNPan110_05850(afr_2)
MRIMal4_34820(afr_7)
SDYNMal52_02280(gfo_2)
PLONPla110_21360(afr_3)
GESVT84_01060(gfo_1) VT84_03575(ycjS)
GOGC1280_16480 C1280_30365
GMSSOIL9_74650 SOIL9_83510
TIMGMBLW1_10240
LRSPX52LOC_02889
FTJFTUN_3203 FTUN_8198
ULIETAA1_50810(gfo_7)
TSPHKIH39_13880
IPAIsop_0786
SACISinac_5779 Sinac_6114
PBORBSF38_01063(gfo_2) BSF38_03488(gfo_6)
AGVOJF2_28930(gfo_7)
KSTKSMBR1_2318(cbaC_1)
PBASSMSP2_00900(ycjS_4) SMSP2_01883(wbpB)
ALUSSTSP2_02795(wbpB)
HBSIPV69_15960
TPEDTPE_0183
TRMJO41_03150
TRZGWP43_02810
TPAVHRQ91_00985 HRQ91_10790
TMEDDWB79_01420
SSMSpirs_3603
STASTHERM_c06180
STQSpith_0632
SPEREW093_13200 EW093_13430
SLRL21SP2_3140
OCKEXM22_01585
SBUSpiBuddy_0091
SGPSpiGrapes_1443 SpiGrapes_1792 SpiGrapes_2991
TAZTREAZ_2637
SCDSpica_2851
LKMEFP84_18045
TPXTurpa_0310
ABAAcid345_3316
SUSAcid_1518
PFERIRI77_04535
ABACLuPra_02895(afr_4)
FUSHMPREF0409_01480
FNEFSDG_01878
FHWRN87_00945
FCII6I83_02410
STRSterm_4053
ACOAmico_1727
TLITlie_1823
CPORBED41_09420
GAUGAU_1966
GPHGEMMAAP_10215
GGRHKW67_04500
GBAJ421_2473
BUNBun01g_30810
PGIPG_2119
PGNPGN_0168(wbpB) PGN_1068
PGTPGTDC60_1302
PAHPoras_0234
PCRENCTC12858_00136(iolG)
PENDLA319_05660
PMUCING2E5A_0875 ING2E5A_0880(iolX1)
PETPEIBARAKI_4689
PPNPalpr_0599
PDIBDI_2789
PARCCI960_20185
PMERINE87_02436
PGOLK6V26_21195
PJOLK449_17465
TFOBFO_1077
TOHBCB71_10490
OSPOdosp_0961
BVIRI6J59_09245 I6J59_14365
TTZFHG85_08190
BLQL21SP5_01622(wbpB)
BACCBRDCF_p620(ycjS) BRDCF_p621
DORIFH5T_09010 FH5T_09100 FH5T_21445
DRCG0Q07_00780 G0Q07_02715
MCOSGM418_10500 GM418_12515 GM418_23735
ASXCDL62_08695
ALKQM9189_00215
RMRRmar_1674
RMGRhom172_1112
RBARAWN76_001865
CBAECOR50_03165
NKONiako_6748
NSONIASO_01490
NIAA8C56_08560
FLASY85_01720
FGGFSB75_02855 FSB75_06700 FSB75_11455
ARBA9P82_11335
AGIFSB73_17185
ARACE0W69_017455
ATEEK9M52_16130
PSEGD3H65_09815
PGINFRZ67_02960 FRZ67_02965
PGOFSB84_21450
FLSGLV81_01885
LACSH4075_01935
FLPLK994_08750
FLCKJS93_05830
FLVKJS94_04580 KJS94_16535
HHYHalhy_2761
SGNSGRA_4064
PHEPhep_0349 Phep_0551
PEJFYC62_11505
PSNPedsa_1140 Pedsa_3258
SPSCE2P86_16385
SPHEGFH32_12500
SCNSolca_3168
MGIKGO620_005155
SBXCA265_19285
CMRCycma_4733
CAMUCA2015_4545
EVIEchvi_3098
ESTDN752_22330
ECHIFKX85_14665 FKX85_20315
ALMAO498_00110
SLISlin_4507
SRDSD10_24330
SMONAWR27_24625
SPIRCWM47_04730
SPIKEXU85_28890
SPIBG8759_06370 G8759_15345
STAEHNV11_19265
SRHOHH216_10170
RSIRunsl_3956
RUNDR864_23540
FAEFAES_5182
FIBA6C57_06070
HSWHsw_1635
HYMN008_00290
HYDPK28_08405
HYEAM218_07895
HYGAUC43_12620
HYPA0257_01145
HYZAXW84_10805
HNVDDQ68_04740
HYHD3Y59_06270
HYJFHG12_00250
HQIH9L05_19910
HRSHER32_18390
HBNGUY19_05570
HTSHMJ29_15375
HMTMTP16_20420
HTBMTX78_09015
RUFTH63_05750
RTIDC20_16625
RUDTH61_13615
NIBGU926_01120
FPFDCC35_01150
FKAKM029_13880
FBTD770_17580 D770_17610
CHKD4L85_11150
FUVJR347_14480
FBRFBFL15_1030
CAPHCGC49_04835
RBIRB2501_00856
ZGAZOBELLIA_1140 ZOBELLIA_1740(wbpB)
SPONHME9304_01540(wbpB)
POMMED152_05725
POBLPB03_07140
PRNBW723_09650
POLABXQ17_13895
POACW731_08025
PHALH9I45_06505
PLITK8354_09870
PPECH9W90_01185
PBATJL193_14510
PCEAJ3359_17210
AHZAPS56_00715
TDIAUW17_02345
TENLPB136_06615
TJETJEJU_1135(wbpB)
TMARMARIT_2536(wbpB)
TMPF9Y86_04690
LUTLupro_06250
LULLPB138_01540
WFUAXE80_01025
SALTAO058_00385
AQBD1818_09115
AQAD1815_20985
AQDD1816_16185
EMARD1013_01180 D1013_17800
PSYNE9099_06905
MGELG5B37_01375
GAAHX109_12625 HX109_13045
ASAGFGM00_16580
FBEFF125_12120
RANRiean_1174
RAIRA0C_1443
RARRIA_1052
RAGB739_0706
RAEG148_0432
RATM949_1164
WVIWeevi_1284
CIHATE47_11365
CHHA0O34_13950
CIOCEQ15_13535
CHRZCO230_02295
CARHEGY05_16495
CGLENCTC11432_02321(ycjS)
CLACEG342_00040
CTAK4412677_01091(yvaA)
CSALNBC122_00346(iolW_1)
CNPM0D58_15450
CCASEIB73_13630
EBVF0358_05705
EFALFH779_00830
ESTEHNV03_10880
APIBG8C43_06600
CIVIMZ16_09065
FBOJ9309_04135
FTEFluta_2062
FLUCHH17_01450
OHOOweho_3295
CHYDH4K34_02510
SHYRLA303_13210
BBAUAEM51_05415 AEM51_07995
IALIALB_2460(wbpB)
MROMROS_2688
CPRVCYPRO_3324
CACICLOAM1565(mviM)
SAFSULAZ_0344
TMMTmari_0583
TMITHEMA_01740
TMWTHMA_0600
TMQTHMB_0600
TMXTHMC_0600
TPTTpet_0333
TNPTnap_0367
TRQTRQ2_0351
TNACTN_0079
THQT2812B_01745
THZCELL2_01820
THRTRQ7_01865
TLETlet_0884
TTATheth_0520
PHYAJ81_09400
TMETmel_1052
TAFTHA_1334
THPBG95_05995
THERY592_06070
TFEJYK00_03495
FNOFnod_1779
FPEFerpe_2053
FIANA23_10385
OCYOSSY52_04570
PMOPmob_0962
MPZMarpi_1464
MARNLN42_07805
DTNDTL3_0340
KOLKole_1641
KPFIX53_00290
MPGTheba_1179
MINFMESINF_2243
ASACATHSA_0559
CNICalni_1806
CABYCabys_972
TOPTOPB45_1236
TCMHL41_05485
THETF1847_01380
CTHITHC_1547
TMAIFVE67_05410
HALREFA46_010675
HUTHuta_2849
HTIHTIA_2755
HRRHZS55_01030 HZS55_02890 HZS55_22175
HPELHZS54_01075 HZS54_02610 HZS54_25835
HLTI7X12_10350 I7X12_14360
HGIABY42_15230
HTUHtur_4428
HSALJMJ58_23625
HXAHalxa_0374 Halxa_0397
HLRHALLA_00600 HALLA_04470
SSOASULA_0826
SSOLSULB_0828
SSOFSULC_0826
SSHIJ5U23_00438
SISLS215_2481
SIAM1425_2309
SIMM1627_2388
SIDM164_2311
SIYYG5714_2446
SINYN1551_0464
SIILD85_2596
SIHSiH_2250
SIRSiRe_2194
SICSiL_2159
SULABFU36_07240
SULEGFS03_12445
SACDHS1genome_1651
CMACmaq_0434
 » show all
Reference
1  [PMID:19282284]
  Authors
Westman EL, McNally DJ, Charchoglyan A, Brewer D, Field RA, Lam JS
  Title
Characterization of WbpB, WbpE, and WbpD and reconstitution of a pathway for the biosynthesis of UDP-2,3-diacetamido-2,3-dideoxy-D-mannuronic acid in Pseudomonas aeruginosa.
  Journal
J Biol Chem 284:11854-62 (2009)
DOI:10.1074/jbc.M808583200
  Sequence
[pae:PA3158]
Reference
2  [PMID:19348502]
  Authors
Larkin A, Imperiali B
  Title
Biosynthesis of UDP-GlcNAc(3NAc)A by WbpB, WbpE, and WbpD: enzymes in the Wbp pathway responsible for O-antigen assembly in Pseudomonas aeruginosa PAO1.
  Journal
Biochemistry 48:5446-55 (2009)
DOI:10.1021/bi900186u
  Sequence
[pae:PA3158]
Reference
3  [PMID:20690587]
  Authors
Thoden JB, Holden HM
  Title
Structural and functional studies of WlbA: A dehydrogenase involved in the biosynthesis of 2,3-diacetamido-2,3-dideoxy-D-mannuronic acid .
  Journal
Biochemistry 49:7939-48 (2010)
DOI:10.1021/bi101103s
  Sequence
[pae:PA3158]
Reference
4  [PMID:21241053]
  Authors
Thoden JB, Holden HM
  Title
Biochemical and structural characterization of WlbA from Bordetella pertussis and Chromobacterium violaceum: enzymes required for the biosynthesis of 2,3-diacetamido-2,3-dideoxy-D-mannuronic acid.
  Journal
Biochemistry 50:1483-91 (2011)
DOI:10.1021/bi101871f
  Sequence
[bpe:BP0093] [cvi:CV_4127]
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.335
IUBMB Enzyme Nomenclature: 1.1.1.335
ExPASy - ENZYME nomenclature database: 1.1.1.335
BRENDA, the Enzyme Database: 1.1.1.335

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