KEGG   ENZYME: 1.1.1.341
Entry
EC 1.1.1.341                Enzyme                                 
Name
CDP-abequose synthase;
rfbJ (gene name)
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
CDP-alpha-D-abequose:NADP+ 4-oxidoreductase
Reaction(IUBMB)
CDP-alpha-D-abequose + NADP+ = CDP-4-dehydro-3,6-dideoxy-alpha-D-glucose + NADPH + H+ [RN:R08711]
Reaction(KEGG)
R08711
Substrate
CDP-alpha-D-abequose [CPD:C01788];
NADP+ [CPD:C00006]
Product
CDP-4-dehydro-3,6-dideoxy-alpha-D-glucose [CPD:C04297];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
Isolated from Yersinia pseudotuberculosis [1,3] and Salmonella enterica [1,2].
History
EC 1.1.1.341 created 2012
Pathway
ec00520  Amino sugar and nucleotide sugar metabolism
ec00541  O-Antigen nucleotide sugar biosynthesis
ec01100  Metabolic pathways
Orthology
K12455  CDP-abequose synthase
K19632  CDP-abequose synthase
Genes
STMSTM2089(rfbJ)
SEOSTM14_2583(rfbJ)
SEVSTMMW_21201
SEYSL1344_2066(rfbJ)
SEMSTMDT12_C21110
SEJSTMUK_2119(rfbJ)
SEBSTM474_2174(rfbJ)
SEFUMN798_2257(rfbJ)
SETUSTU288_06830
SETCCFSAN001921_06335
SENRSTMDT2_20631
SENDDT104_21481
SEENSE451236_16655
SPQSPAB_00941
SEHSeHA_C2315
SHBSU5_02683
SENHCFSAN002069_21375
SEEHSEEH1578_19725
SEWSeSA_A2322
SEASeAg_B2214
SENSQ786_10315
YPQDJ40_1357
YPRBZ20_1044
PAKHB0X70_24655
PLUICE143_24695
SKHSTH12_02109(rfbJ)
SAVIJYB87_13140
MPAUZMTM_15440(prt)
CINFCINF_0710
AOZHUE56_00360
PLUTEI981_25810
LFSHFV01_27460
DRCG0Q07_02765
SABUMBM09_01935
 » show all
Reference
1  [PMID:1724263]
  Authors
Kessler AC, Brown PK, Romana LK, Reeves PR
  Title
Molecular cloning and genetic characterization of the rfb region from Yersinia pseudotuberculosis serogroup IIA, which determines the formation of the 3,6-dideoxyhexose abequose.
  Journal
J Gen Microbiol 137:2689-95 (1991)
DOI:10.1099/00221287-137-12-2689
  Sequence
Reference
2  [PMID:2793832]
  Authors
Wyk P, Reeves P
  Title
Identification and sequence of the gene for abequose synthase, which confers antigenic specificity on group B salmonellae: homology with galactose epimerase.
  Journal
J Bacteriol 171:5687-93 (1989)
DOI:10.1128/JB.171.10.5687-5693.1989
  Sequence
[stm:STM2089]
Reference
3  [PMID:8071227]
  Authors
Thorson JS, Lo SF, Ploux O, He X, Liu HW
  Title
Studies of the biosynthesis of 3,6-dideoxyhexoses: molecular cloning and characterization of the asc (ascarylose) region from Yersinia pseudotuberculosis serogroup VA.
  Journal
J Bacteriol 176:5483-93 (1994)
DOI:10.1128/JB.176.17.5483-5493.1994
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.341
IUBMB Enzyme Nomenclature: 1.1.1.341
ExPASy - ENZYME nomenclature database: 1.1.1.341
BRENDA, the Enzyme Database: 1.1.1.341

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