KEGG ENZYME: 1.1.1.341

ENZYME: 1.1.1.341

Entry

EC 1.1.1.341 Enzyme

Name

CDP-abequose synthase;
rfbJ (gene name)

Class

Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor

Sysname

CDP-alpha-D-abequose:NADP+ 4-oxidoreductase

Reaction(IUBMB)

CDP-alpha-D-abequose + NADP+ = CDP-4-dehydro-3,6-dideoxy-alpha-D-glucose + NADPH + H+ [RN:R08711]

Reaction(KEGG)

R08711

Substrate

CDP-alpha-D-abequose [CPD:C01788];
NADP+ [CPD:C00006]

Product

CDP-4-dehydro-3,6-dideoxy-alpha-D-glucose [CPD:C04297];
NADPH [CPD:C00005];
H+ [CPD:C00080]

Comment

Isolated from Yersinia pseudotuberculosis [1,3] and Salmonella enterica [1,2].

History

EC 1.1.1.341 created 2012

Pathway

ec00520

Amino sugar and nucleotide sugar metabolism

ec00541

O-Antigen nucleotide sugar biosynthesis

ec01100

Metabolic pathways

Orthology

K12455

CDP-abequose synthase

K19632

CDP-abequose synthase

Genes

STM:	STM2089(rfbJ)

SEO:	STM14_2583(rfbJ)

SEV:	STMMW_21201

SEY:	SL1344_2066(rfbJ)

SEM:	STMDT12_C21110

SEJ:	STMUK_2119(rfbJ)

SEB:	STM474_2174(rfbJ)

SEF:	UMN798_2257(rfbJ)

SETU:

SETC:

SENR:

SEND:

SEEN:

SPQ:	SPAB_00941

SEH:	SeHA_C2315

SHB:

SU5_02683

SENH:

CFSAN002069_21375

SEEH:

SEEH1578_19725

SEW:	SeSA_A2322

SEA:	SeAg_B2214

SENS:

YPQ:

YPR:

PAKH:

SKH:	STH12_02109(rfbJ)

MPAU:

ZMTM_15440(prt)

CINF:

CINF_0710

AOZ:	HUE56_00360

PLUT:

EI981_25810

LFS:	HFV01_27460

DRC:	G0Q07_02765

» show all

Reference

1 [PMID:1724263]

Authors

Kessler AC, Brown PK, Romana LK, Reeves PR

Title

Molecular cloning and genetic characterization of the rfb region from Yersinia pseudotuberculosis serogroup IIA, which determines the formation of the 3,6-dideoxyhexose abequose.

Journal

J Gen Microbiol 137:2689-95 (1991)
DOI:10.1099/00221287-137-12-2689

Sequence

[ag:AAB49402]

Reference

2 [PMID:2793832]

Authors

Wyk P, Reeves P

Title

Identification and sequence of the gene for abequose synthase, which confers antigenic specificity on group B salmonellae: homology with galactose epimerase.

Journal

J Bacteriol 171:5687-93 (1989)
DOI:10.1128/JB.171.10.5687-5693.1989

Sequence

[stm:STM2089]

Reference

3 [PMID:8071227]

Authors

Thorson JS, Lo SF, Ploux O, He X, Liu HW

Title

Studies of the biosynthesis of 3,6-dideoxyhexoses: molecular cloning and characterization of the asc (ascarylose) region from Yersinia pseudotuberculosis serogroup VA.

Journal

J Bacteriol 176:5483-93 (1994)
DOI:10.1128/JB.176.17.5483-5493.1994

Other DBs

ExplorEnz - The Enzyme Database:

1.1.1.341

IUBMB Enzyme Nomenclature:

1.1.1.341

ExPASy - ENZYME nomenclature database:

1.1.1.341

BRENDA, the Enzyme Database:

1.1.1.341

DBGET integrated database retrieval system