Entry |
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Name |
CDP-abequose synthase;
rfbJ (gene name)
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Class |
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
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Sysname |
CDP-alpha-D-abequose:NADP+ 4-oxidoreductase
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Reaction(IUBMB) |
CDP-alpha-D-abequose + NADP+ = CDP-4-dehydro-3,6-dideoxy-alpha-D-glucose + NADPH + H+ [RN: R08711]
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Reaction(KEGG) |
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Substrate |
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Product |
CDP-4-dehydro-3,6-dideoxy-alpha-D-glucose [CPD: C04297];
NADPH [CPD: C00005];
H+ [CPD: C00080]
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Comment |
Isolated from Yersinia pseudotuberculosis [1,3] and Salmonella enterica [1,2].
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History |
EC 1.1.1.341 created 2012
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Pathway |
ec00520 | Amino sugar and nucleotide sugar metabolism |
ec00541 | O-Antigen nucleotide sugar biosynthesis |
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Orthology |
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Genes |
» show all
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Reference |
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Authors |
Kessler AC, Brown PK, Romana LK, Reeves PR |
Title |
Molecular cloning and genetic characterization of the rfb region from Yersinia pseudotuberculosis serogroup IIA, which determines the formation of the 3,6-dideoxyhexose abequose. |
Journal |
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Sequence |
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Reference |
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Authors |
Wyk P, Reeves P |
Title |
Identification and sequence of the gene for abequose synthase, which confers antigenic specificity on group B salmonellae: homology with galactose epimerase. |
Journal |
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Sequence |
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Reference |
|
Authors |
Thorson JS, Lo SF, Ploux O, He X, Liu HW |
Title |
Studies of the biosynthesis of 3,6-dideoxyhexoses: molecular cloning and characterization of the asc (ascarylose) region from Yersinia pseudotuberculosis serogroup VA. |
Journal |
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Other DBs |
ExPASy - ENZYME nomenclature database: | 1.1.1.341 |
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