KEGG   ENZYME: 1.1.1.346Help
Entry
EC 1.1.1.346                Enzyme                                 

Name
2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming);
2,5-diketo-D-gluconate-reductase (ambiguous);
YqhE reductase;
dkgA (gene name);
dkgB (gene name)
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
2-dehydro-D-gluconate:NADP+ 2-oxidoreductase (2-dehydro-L-gulonate-forming)
Reaction(IUBMB)
2-dehydro-L-gulonate + NADP+ = 2,5-didehydro-D-gluconate + NADPH + H+ [RN:R08878]
Reaction(KEGG)
Substrate
2-dehydro-L-gulonate;
NADP+ [CPD:C00006]
Product
2,5-didehydro-D-gluconate [CPD:C02780];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
The enzyme is involved in ketogluconate metabolism, and catalyses the reaction in vivo in the reverse direction to that shown [1]. It is used in the commercial microbial production of ascorbate. cf. EC 1.1.1.274, 2,5-didehydrogluconate reductase (2-dehydro-D-gluconate-forming).
History
EC 1.1.1.346 created 2013
Orthology
K06221  2,5-diketo-D-gluconate reductase A
K06222  2,5-diketo-D-gluconate reductase B
Genes
OTW: 112243452
DSR: 110180742
PXY: 105384222
ZJU: 107408113
ECO: b0207(dkgB) b3012(dkgA)
ECJ: JW0197(dkgB) JW5499(dkgA)
ECD: ECDH10B_0188(dkgB) ECDH10B_3187(dkgA)
EBW: BWG_0194(dkgB) BWG_2726(dkgA)
ECOK: ECMDS42_0195(dkgB) ECMDS42_2488(dkgA)
ECE: Z0229(yafB) Z0374 Z4365(yqhE)
ECS: ECs0203(dkgB) ECs0335 ECs3896(dkgA)
ETW: ECSP_0206(dkgB) ECSP_0345 ECSP_3988(dkgA)
EOI: ECO111_0204(dkgB) ECO111_3839(dkgA)
EOJ: ECO26_0206(dkgB) ECO26_4117(dkgA)
EOH: ECO103_0201(dkgB) ECO103_3694(dkgA)
ECOH: ECRM13516_0218(dkgB) ECRM13516_3781(dkgA)
ESL: O3K_03865(dkgA) O3K_20550(dkgB)
ESO: O3O_04830(dkgB) O3O_21780(dkgA)
ESM: O3M_03900(dkgA) O3M_20450(dkgB)
ECK: EC55989_0205(dkgB) EC55989_3429(dkgA)
EOK: G2583_0211(dkgB) G2583_0396 G2583_3736(dkgA)
ECW: EcE24377A_0213(dkgB) EcE24377A_3480(dkgA)
ECOS: EC958_0350(dkgB) EC958_0447 EC958_3404(dkgA)
ECX: EcHS_A0211(dkgB) EcHS_A3190(dkgA)
ECR: ECIAI1_0215(dkgB) ECIAI1_3161(dkgA)
ECQ: ECED1_0212(dkgB) ECED1_3662(dkgA)
EUM: ECUMN_0204(dkgB) ECUMN_0336 ECUMN_3496(dkgA)
EOC: CE10_0212(dkgB) CE10_0263 CE10_3543(dkgA)
EBR: ECB_00200(dkgB) ECB_02885(dkgA)
EBL: ECD_00200(dkgB) ECD_02885(dkgA)
EBE: B21_00205(dkgB) B21_02835(dkgA)
EIH: ECOK1_0210(dkgB) ECOK1_0289 ECOK1_3428(dkgA)
ECZ: ECS88_0222(dkgB) ECS88_0299 ECS88_3392(dkgA)
ECC: c0244(yafB) c0414 c3746
ELO: EC042_0200(dkgB) EC042_0332 EC042_3301(dkgA)
EKF: KO11_00980(dkgB) KO11_07625(dkgA)
ELW: ECW_m0204(dkgB) ECW_m3283(dkgA)
ELL: WFL_00980(dkgB) WFL_16045(dkgA)
ELC: i14_0226(dkgB) i14_0396 i14_3438(dkgA)
ELD: i02_0226(dkgB) i02_0396 i02_3438(dkgA)
ELP: P12B_c0190(dkgB) P12B_c3113(dkgA)
ELF: LF82_0493(dkgA) LF82_0494(dkgB) LF82_053
ECOL: LY180_01010(dkgB) LY180_15580(dkgA)
ECOI: ECOPMV1_00215(dkgB) ECOPMV1_00297(yvgN_1) ECOPMV1_03314(dkgA)
ECOJ: P423_01105(dkgB) P423_01610(dkgA) P423_16990(dkgA)
EFE: EFER_0236(dkgB) EFER_2672 EFER_2952(dkgA)
EAL: EAKF1_ch1214c(dkgB) EAKF1_ch2926c(dkgA)
STY: STY0276(yafB)
STT: t2610(yafB)
SENT: TY21A_13240(dkgB)
STM: STM0255(yafB) STM3165(yqhE)
SEO: STM14_0300(dkgB) STM14_3832(dkgA)
SEY: SL1344_0250(dkgB) SL1344_3139(dkgA)
SEM: STMDT12_C02510(dkgB) STMDT12_C32200(dkgA)
SEJ: STMUK_0257(dkgB) STMUK_3153(dkgA)
SEB: STM474_0266(dkgB) STM474_3316(dkgA)
SEF: UMN798_0279(yafB) UMN798_3441(dkgA)
SETU: STU288_13470(dkgB) STU288_16025(dkgA)
SENR: STMDT2_02511(yafB) STMDT2_30591(dkgA)
SEND: DT104_02541(yafB) DT104_31611(dkgA)
SENI: CY43_01280(dkgB) CY43_16495(dkgA)
SEEN: SE451236_07295(dkgB) SE451236_21945(dkgA)
SPT: SPA2514(yafB) SPA3033(yqhE)
SEI: SPC_0265(yafB) SPC_3236(yqhE)
SEC: SCH_0251(yafB) SCH_3109(yqhE)
SEEH: SEEH1578_01965(dkgA) SEEH1578_10365(dkgB)
SENS: Q786_01335(dkgB) Q786_15375(dkgA)
SED: SeD_A0278(dkgB) SeD_A3515
SEG: SG0253(yafB) SG3062(yqhE)
SEL: SPUL_2727(yafB) SPUL_3173(yqhE)
SEGA: SPUCDC_2713(yafB) SPUCDC_3159(yqhE)
SET: SEN0257(yafB) SEN3008(yqhE)
SENA: AU38_01300(dkgB) AU38_15295(dkgA)
SENO: AU37_01300(dkgB) AU37_15300(dkgA)
SENV: AU39_01300(dkgB) AU39_15300(dkgA)
SENQ: AU40_01475(dkgB) AU40_17235(dkgA)
SENL: IY59_01325(dkgB) IY59_15900(dkgA)
SEEB: SEEB0189_004050(dkgA) SEEB0189_018030(dkgB)
SEEP: I137_12755(dkgB) I137_15145(dkgA)
SENB: BN855_2650(yafB) BN855_32430(yqhE)
SENE: IA1_01365(dkgB) IA1_15290(dkgA)
SENC: SEET0819_08205(dkgB) SEET0819_22830(dkgA)
SBG: SBG_1861 SBG_2762(dkgA)
SBZ: A464_3200
SBV: N643_13760(dkgA)
SALZ: EOS98_03495(dkgA) EOS98_17930(dkgB)
SFL: SF0192(dkgB) SF3057(yqhE)
SFX: S0200(yafB) S3260(yqhE)
SFV: SFV_0190(yafB) SFV_3062(yqhE)
SFE: SFxv_0204(dkgB) SFxv_3355(dkgA)
SFT: NCTC1_00203(dkgB) NCTC1_03310(dkgA)
SSN: SSON_0221(yafB) SSON_3155(yqhE)
SBO: SBO_0196(yafB) SBO_3006(yqhE)
SBC: SbBS512_E0204(dkgB) SbBS512_E3440(dkgA)
SDY: SDY_0226(dkgB) SDY_3061(dkgA)
SHQ: A0259_04885(dkgB) A0259_18800(dkgA)
ENO: ECENHK_04455(dkgB) ECENHK_18835(dkgA)
ENL: A3UG_04220(dkgB) A3UG_19225(dkgA)
ECLE: ECNIH2_05185(dkgB) ECNIH2_19445(dkgA)
ECLN: ECNIH4_03905(dkgA) ECNIH4_18505(dkgB)
ECLI: ECNIH5_04250(dkgB) ECNIH5_18255(dkgA)
ECLX: LI66_04260(dkgB) LI66_19015(dkgA)
ECLY: LI62_04775(dkgB) LI62_20960(dkgA)
ECLZ: LI64_04435(dkgB) LI64_17880(dkgA)
EHM: AB284_06665(dkgA) AB284_20700(dkgB)
ECLA: ECNIH3_04240(dkgB) ECNIH3_18340(dkgA)
ECLC: ECR091_04220(dkgB) ECR091_18275(dkgA)
EAU: DI57_00405(dkgA) DI57_14380(dkgB)
EEC: EcWSU1_00814(dkgB) EcWSU1_03798(dkgA)
ECLS: LI67_005190(dkgB) LI67_020570(dkgA)
ECHG: FY206_04930(dkgB) FY206_20755(dkgA)
ENR: H650_11535(dkgA) H650_19855(dkgB)
ENX: NI40_004050(dkgB) NI40_018640(dkgA)
EBG: FAI37_02360(dkgB) FAI37_10270(dkgA)
END: A4308_03510(dkgA) A4308_08310(dkgB)
CSK: ES15_0565(dkgA) ES15_3128(dkgB)
CCON: AFK62_17070(dkgA)
CDM: AFK67_04190(dkgB) AFK67_17645(dkgA)
CMJ: AFK66_002895(dkgA) AFK66_015535(dkgB)
CUI: AFK65_04135(dkgB) AFK65_16800(dkgA)
CMW: AFK63_01610(dkgA) AFK63_14420(dkgB)
CTU: CTU_36030(dkgA)
KPN: KPN_00221(dkgB) KPN_03432(dkgA)
KPU: KP1_1065(dkgB) KP1_4712(dkgA) KP1_p057
KPH: KPNIH24_06090(dkgA) KPNIH24_24050(dkgB)
KPZ: KPNIH27_04585(dkgB) KPNIH27_21760(dkgA)
KPW: KPNIH30_05005(dkgB) KPNIH30_22960(dkgA)
KPY: KPNIH31_03045(dkgB) KPNIH31_21880(dkgA)
KPG: KPNIH32_05010(dkgB) KPNIH32_23815(dkgA)
KPC: KPNIH10_04760(dkgB) KPNIH10_22710(dkgA)
KPQ: KPR0928_04770(dkgB) KPR0928_22220(dkgA)
KPE: KPK_0689(dkgA) KPK_4513(dkgB)
KPR: KPR_1148(dkgB) KPR_4463(dkgA)
KPI: D364_01075(dkgB) D364_03020 D364_17675(dkgA)
KPX: PMK1_00906(dkgA) PMK1_02526(dkgB)
KPB: FH42_13425(dkgA) FH42_21955(dkgB)
KPNE: KU54_003620(dkgA) KU54_021740(dkgB)
KPNU: LI86_03625(dkgA) LI86_11045 LI86_21580(dkgB)
KPNK: BN49_0676(dkgA) BN49_1190(dkgB)
KPK: A593_07215(dkgA) A593_15505(dkgB)
KOX: KOX_02300 KOX_02895(dkgA) KOX_11620(dkgB)
KOY: J415_06870(dkgA) J415_07530 J415_26090(dkgB)
KOM: HR38_00605 HR38_01270(dkgA) HR38_10380(dkgB)
KMI: VW41_04005(dkgB) VW41_20345(dkgA) VW41_23680(dkgB)
KOC: AB185_10890(dkgA) AB185_30800(dkgB)
EAE: EAE_03505(dkgA) EAE_11805(dkgB)
CRO: ROD_02121(dkgA) ROD_35601(dkgA)
CFD: CFNIH1_02325(dkgA) CFNIH1_10710(dkgB)
CAMA: F384_01070(dkgB) F384_04655 F384_25165(dkgA)
RON: TE10_06845(dkgB) TE10_24165(dkgA)
CNT: JT31_08260(dkgB) JT31_15590(dkgA)
CEM: LH23_02120(dkgA) LH23_09460(dkgB)
CEN: LH86_02095(dkgA) LH86_09515(dkgB)
CLAP: NCTC11466_00539(dkgA) NCTC11466_03718(dkgB)
PGE: LG71_07675(dkgA)
KLE: AO703_04295(dkgB) AO703_17885(dkgA)
KOR: AWR26_03440(dkgA) AWR26_20465(dkgB)
KRD: A3780_03275(dkgB) A3780_21085(dkgA)
KOT: EH164_03115(dkgA) EH164_18015(dkgB)
LAX: APT61_03710(dkgA) APT61_18070(dkgB)
LER: GNG29_04500(dkgB) GNG29_19285(dkgA)
LEA: GNG26_03985(dkgB) GNG26_18740(dkgA)
LNI: CWR52_07935(dkgB) CWR52_16190(dkgA)
AHN: NCTC12129_00841(dkgA_1)
IZH: FEM41_01685(dkgA)
YRE: HEC60_14605(dkgA) HEC60_22175(dkgB)
PSTS: E05_03560 E05_43610(yqhE)
YPE: YPO0676(dkgA) YPO1075(dkgB) YPO2805
YPM: YP_1162(aRA11) YP_2774(aRA13) YP_2991(aRA14)
YPW: CH59_1188(dkgA) CH59_3687 CH59_778(dkgB)
YPJ: CH55_1627 CH55_2137(dkgA) CH55_3831(dkgB)
YPV: BZ15_2489(dkgB) BZ15_2899(dkgA) BZ15_723
YPL: CH46_2299 CH46_242(dkgA) CH46_4063(dkgB)
YPO: BZ17_1494 BZ17_3221(dkgA) BZ17_3655(dkgB)
YPQ: DJ40_1222 DJ40_3039(dkgA) DJ40_3516(dkgB)
YPU: BZ21_2278(dkgB) BZ21_2669(dkgA) BZ21_300
YPR: BZ20_2739(dkgA) BZ20_3199(dkgB) BZ20_975
YPC: BZ23_2558(dkgB) BZ23_2957(dkgA) BZ23_577
YEN: YE0912(dkgB) YE3031 YE3652(dkgA)
YEW: CH47_2398 CH47_316(dkgB) CH47_4148(dkgA)
YET: CH48_2267(dkgA) CH48_692(dkgB)
YSI: BF17_01305(dkgB) BF17_04130(dkgA)
YAL: AT01_1940(dkgA)
YFR: AW19_2489 AW19_2654(dkgA) AW19_69(dkgB)
YIN: CH53_2367(dkgA)
YRO: CH64_1618 CH64_2028(dkgA)
YRU: BD65_1374(dkgA)
YRB: UGYR_07590(dkgA)
YAK: ACZ76_04450(dkgB) ACZ76_06160(dkgA)
YCA: F0T03_05085(dkgB) F0T03_18680(dkgA)
SMAR: SM39_0187(dkgB) SM39_0282 SM39_3682(dkgA)
SMAC: SMDB11_0187(dkgB) SMDB11_3487(dkgA)
SMW: SMWW4_v1c08520(dkgB) SMWW4_v1c41810(dkgA)
SRL: SOD_c07600(dkgB) SOD_c40630(dkgA)
SRY: M621_04200(dkgB) M621_22170(dkgA)
SPLY: Q5A_004050(dkgB) Q5A_022140(dkgA)
SLQ: M495_03800(dkgB) M495_21285(dkgA)
SERF: L085_07140(dkgA) L085_24175(dkgB)
SERS: SERRSCBI_03970(dkgB) SERRSCBI_20320(dkgA)
SFW: WN53_04095(dkgA) WN53_13295(dkgB)
RAA: Q7S_02935(dkgA) Q7S_04315(dkgB) Q7S_04635
ECA: ECA0349(dkgA)
PATR: EV46_01865(dkgA)
PATO: GZ59_03790(dkgA)
PCT: PC1_0336
PCV: BCS7_01745(dkgA)
PEC: W5S_0357
PPUJ: E2566_01970(dkgA)
SGL: SG0278
SOD: Sant_3594(dkgA) Sant_3639
DDD: Dda3937_01193(dkgB) Dda3937_01257(dkgA)
DZC: W909_01740(dkgA)
DSO: A4U42_10915(dkgA) A4U42_12895(dkgB)
CED: LH89_08520(dkgB) LH89_10415(dkgA)
DDQ: DDI_0103
DAQ: DAQ1742_00430(dkgA)
DIC: Dpoa569_003619(dkgA)
BGJ: AWC36_11215(dkgB) AWC36_16545(dkgA)
BRB: EH207_01375(dkgA)
BNG: EH206_20555(dkgA)
EAM: EAMY_0463(yqhE)
EAY: EAM_2962(dkgA)
ETA: ETA_04440(dkgA) ETA_24000
EPY: EpC_04480(dkgA) EpC_30520
EPR: EPYR_00471(yqhE) EPYR_03292(yqhE)
EBI: EbC_08400(dkgB) EbC_25540 EbC_38280(dkgA)
ERJ: EJP617_16120(dkgA)
EGE: EM595_0556(yqhE)
PAM: PANA_3355(dkgA)
PLF: PANA5342_0705(dkgA)
PAJ: PAJ_2600(dkgA)
PVA: Pvag_2637(yqhE)
KLN: LH22_05500(dkgA) LH22_18320(dkgB)
PANT: PSNIH1_02910(dkgA)
PANP: PSNIH2_01300(dkgA)
PSTW: DSJ_20395
PANS: FCN45_03985(dkgB) FCN45_16500(dkgA)
PEY: EE896_03290(dkgA)
MINT: C7M51_02738(dkgA)
MTHI: C7M52_00118(dkgA)
PLU: plu1527(dkgB) plu3946(dkgA)
PLUM: A4R40_07750(dkgB) A4R40_19620(dkgA)
PAY: PAU_03522(dkgA)
PTT: VY86_13720(dkgA) VY86_19900(dkgB)
PMR: PMI0024(dkgA) PMI0802(dkgB)
PMIB: BB2000_0189(dkgA) BB2000_0870(dkgB)
PVL: AOB99_02980(dkgA) AOB99_06445(dkgB)
PCIB: F9282_02950(dkgA)
PCOL: F1325_03090(dkgA)
XBO: XBJ1_1718(dkgA)
XBV: XBW1_1040(dkgA)
XNE: XNC1_3760(dkgA)
XNM: XNC2_3615(dkgA)
XDO: XDD1_0796(dkgA)
XPO: XPG1_2978(dkgA)
MMK: MU9_859
ANS: ArsFIN_19080(dkgB_1)
ETR: ETAE_3188(dkgA)
ETE: ETEE_1414
ETC: ETAC_15180(dkgA)
EDW: QY76_04585(dkgA)
EDL: AAZ33_16620(dkgA)
PDZ: HHA33_06115(dkgA)
MSU: MS1209(ara1)
MVR: X781_5300
AAT: D11S_0673
AAN: D7S_00997
AACN: AANUM_0729
BTO: WQG_2480
BTRE: F542_19480
BTRH: F543_21370
XCC: XCC0269(dkgB)
XCB: XC_0279
XCP: XCR_4242
XOM: XOO4264(XOO4264)
XOO: XOO4527
XOP: PXO_03276
XOY: AZ54_23855(dkgB)
XOR: XOC_4615
XOZ: BE73_00440(dkgB)
XAR: XB05_18140(dkgB)
XHY: FZ025_09985(dkgB)
SMT: Smal_3899
STEK: AXG53_19000(dkgB)
PSD: DSC_04780
LEZ: GLE_5346(dkgB)
LEM: LEN_4886
DJA: HY57_11390(dkgB)
VAG: N646_0676
VEJ: VEJY3_09060(dkgB)
VAN: VAA_00990
LAG: N175_18255(dkgB)
VAU: VANGNB10_cII0246c(dkgB)
VCY: IX92_24480(dkgB)
VCT: JV59_23385(dkgB)
VNL: D3H41_08475(dkgB)
VAS: GT360_19315(dkgB)
PAE: PA4167
PAEV: N297_4299
PAEI: N296_4299
PAU: PA14_09980(yafB)
PAF: PAM18_0770(dkgB)
PNC: NCGM2_5370(dkgB)
PAEB: NCGM1900_0789(dkgB)
PSG: G655_03870(dkgB)
PRP: M062_21965(dkgB)
PAEP: PA1S_03985(dkgB)
PAEM: U769_04015(dkgB)
PAEL: T223_03920(dkgB)
PAEU: BN889_04634(dkgB)
PAEG: AI22_29630(dkgB)
PAEC: M802_4297
PAEO: M801_4165
PMY: Pmen_0068
PMK: MDS_0087
PPSE: BN5_0042(dkgB)
PCQ: PcP3B5_33800(dkgB_1) PcP3B5_36070(dkgB_2)
PPU: PP_2368(dkgB) PP_3671
PPX: T1E_1749(dkgB) T1E_5313
PPUH: B479_09680(dkgB) B479_15755
PPUT: L483_09610(dkgB) L483_19260
PPUN: PP4_21220 PP4_34460(dkgB)
PMON: X969_07735(dkgB) X969_15270
PMOT: X970_07710(dkgB) X970_14915
PMOS: O165_012835(dkgB)
PFL: PFL_4075(dkgB) PFL_5394
PPRC: PFLCHA0_c41340(dkgB1) PFLCHA0_c53660(dkgB2)
PPRO: PPC_4174(dkgB) PPC_5364
PFS: PFLU_2183(dkgB)
PFN: HZ99_00315(dkgB)
PPZ: H045_06405(dkgB)
PMAN: OU5_1403
PTV: AA957_03710(dkgB)
PAZO: AYR47_17910(dkgB)
PFW: PF1751_v1c20060(dkgB)
PFF: PFLUOLIPICF726690(dkgB)
PEN: PSEEN3411(dkgB)
PSTT: CH92_16515
PDR: H681_13350(dkgB)
PSK: U771_11320(dkgB)
PKC: PKB_2645
PCH: EY04_20685(dkgB)
PCP: JM49_10570(dkgB)
PFZ: AV641_16080(dkgB)
PPV: NJ69_07530(dkgB)
PSES: PSCI_4433
PSEM: TO66_13925(dkgB)
PSEC: CCOS191_2077(dkgB)
PPSY: AOC04_13425(dkgB)
PSOS: POS17_5352
PANR: A7J50_2195
PSIL: PMA3_20075(dkgB)
PALI: A3K91_2349
PSYA: AOT82_2267
ACB: A1S_3439
ABM: ABSDF3630(alrA)
ABY: ABAYE0039(alrA)
ABN: AB57_3896
ABB: ABBFA_00038(dkgB)
ABX: ABK1_3692
ABZ: ABZJ_03830(dkgB)
ABD: ABTW07_3844(alrA)
ABAD: ABD1_33430(dkgB)
ABAZ: P795_0190
ABAU: IX87_14240(dkgB) IX87_19915
ABAA: IX88_01995(dkgB)
ABW: BL01_06715(dkgB)
ACC: BDGL_002911(alrA) BDGL_002912(alrA2)
ANO: RR32_00205(dkgB)
ACD: AOLE_00180(dkgB)
ACI: ACIAD3616(alrA)
ACW: A0J50_00110(dkgB)
AWU: BEN71_00975(dkgB)
ACUM: C9E88_011405(dkgB)
AGU: AS4_00560(dkgB)
SFR: Sfri_0210
SPOL: FH971_00930(dkgB)
PAT: Patl_4134
PSM: PSM_B0477
PBW: D172_019250(dkgB)
PEA: PESP_b0672(dkgB)
PART: PARC_b0593(dkgB)
PTD: PTET_a0456(dkgB) PTET_a0460(dkgB) PTET_b0593(dkgB)
PDJ: D0907_07820(dkgB) D0907_16495(dkgB)
PAGA: PAGA_b0747(dkgB)
MAD: HP15_833(dkgB)
MARI: ACP86_15285(dkgB)
MARA: D0851_17910(dkgB)
MARJ: MARI_09570(dkgB)
AAL: EP13_07315(dkgB)
AAUS: EP12_07415(dkgB)
ASQ: AVL57_09260(dkgB) AVL57_16010(dkgB)
AAW: AVL56_08150(dkgB) AVL56_14945(dkgB)
ALE: AV939_08275(dkgB) AV939_14920(dkgB)
ALZ: AV940_08095(dkgB) AV940_14670(dkgB)
APEL: CA267_002545(dkgB)
SALM: D0Y50_01095(dkgB) D0Y50_06460(dkgB)
SALK: FBQ74_11105(dkgB)
FBL: Fbal_1799
TTU: TERTU_2150(dkgB)
MTHD: A3224_15410(dkgB)
LCD: clem_01040(dkgB)
CSA: Csal_1316
HEL: HELO_1287(dkgB)
HHU: AR456_02090(dkgB)
HBE: BEI_1125(dkgB)
HOL: HORIV_15540(dkgB)
APAC: S7S_15135
BMAR: HF888_04485(dkgB)
AHA: AHA_1644(dkgB)
ASA: ASA_2717
AVR: B565_2512
AMED: B224_3482
ACAV: VI35_07090
TAU: Tola_1333
SALN: SALB1_2461
CVI: CV_0701
CRZ: D1345_23060(dkgB)
PSE: NH8B_3779
RSC: RCFBP_20279(dkgB)
RSM: CMR15_20359(dkgB)
RSY: RSUY_15720(dkgB)
RPI: Rpic_2695
RPJ: N234_11220(dkgB)
RMN: TK49_14925(dkgB)
REH: H16_B2162(h16_B2162)
CNC: CNE_2c21320(dkgB)
RME: Rmet_5364(dkgB)
CTI: RALTA_B1285(dkgB)
CGD: CR3_4011(dkgB)
BPSA: BBU_5895
BTQ: BTQ_5437
BTJ: BTJ_4093
BTZ: BTL_4905
BTV: BTHA_5318
BTHE: BTN_4562
BTHM: BTRA_4827
BTHA: DR62_4671(dkgB)
BTHL: BG87_4894
BOK: DM82_6090
BOC: BG90_4575
BVE: AK36_3155
BCN: Bcen_5450
BCJ: BCAM2605(dkgB)
BCEW: DM40_3213
BCEO: I35_6503(dkgB)
BAM: Bamb_4753
BMU: Bmul_3351
BMK: DM80_4731
BCT: GEM_5776
BCED: DM42_5367
BCEP: APZ15_23540(dkgB)
BDL: AK34_3262
BPYR: ABD05_22675(dkgB)
BCON: NL30_16840(dkgB)
BUB: BW23_18
BDF: WI26_25750(dkgB)
BLAT: WK25_28655(dkgB)
BTEI: WS51_09820(dkgB)
BSEM: WJ12_32940(dkgB)
BPSL: WS57_01215(dkgB) WS57_17455
BMEC: WJ16_31435(dkgB)
BSTG: WT74_27270(dkgB)
BGU: KS03_2631
BGO: BM43_2639
BUK: MYA_3239
BUM: AXG89_13910(dkgB)
BUI: AX768_07785(dkgB)
PARA: BTO02_11170(dkgB)
PMEG: FNZ07_07195(dkgB)
PPK: U875_20000(dkgB)
PPNO: DA70_12690(dkgB)
PPNM: LV28_18010(dkgB)
PPUL: RO07_16985
PSPU: NA29_08360
PAPI: SG18_19160(dkgB)
PFIB: PI93_016405(dkgB)
PLG: NCTC10937_03950(dkgB)
CABA: SBC2_20290(dkgB)
BPE: BP1609(dkgB)
BPC: BPTD_0896 BPTD_1591(dkgB)
BPER: BN118_1812
BPET: B1917_1533(dkgB) B1917_2924
BPEU: Q425_17880(dkgB) Q425_8350
BPAR: BN117_2677
BHZ: ACR54_02057(dkgB) ACR54_02781(dkgA)
AXY: AXYL_00268(dkgB) AXYL_02324(dkgA)
AXX: ERS451415_02120(dkgA) ERS451415_05214(dkgB_2)
PUT: PT7_2609
AMIM: MIM_c13750 MIM_c21070(dkgB)
AFQ: AFA_17365
ODI: ODI_R3440
PIG: EGT29_14485(dkgB)
POO: F7R28_02290(dkgB)
AAV: Aave_0287
AAA: Acav_0345
DAC: Daci_0945
VPD: VAPA_1c09460(dkgB)
VAA: AX767_07040(dkgB)
CTES: O987_17135(dkgB) O987_22630
HYB: Q5W_07015
JAG: GJA_4707(dkgB)
JAS: FJQ89_21405(dkgB)
HHF: E2K99_05585(dkgB)
CFU: CFU_1650(yafB)
CARE: LT85_3073
MNR: ACZ75_15130(dkgB)
MFLA: GO485_19645(dkgB)
RGU: A4W93_19525(dkgB)
SLT: Slit_1343
AZO: azo3631(yafB)
AOA: dqs_3776
CCOI: YSU_01105
SULJ: SJPD1_2089
GUR: Gura_4373
GBM: Gbem_3980(yvgN)
DPI: BN4_11130(yvgN)
HOH: Hoch_6096
MLO: mll1906
MHUA: MCHK_1345(dkgB) MCHK_3465
MES: Meso_3052
AMIH: CO731_00990(dkgB_2)
SME: SMa1410
SMD: Smed_0580
SFH: SFHH103_00660(yafB)
SFD: USDA257_c06950(dkgB)
SAME: SAMCFNEI73_Ch1030(dkgB)
AVI: Avi_4225(yafB)
RLE: RL4557(dkgA) pRL120107
RLG: Rleg_4086
RHT: NT26_0788(dkgB)
BME: BMEII1060
BMEL: DK63_2198
BMEE: DK62_3210
BMF: BAB2_0177
BABO: DK55_2174
BABR: DO74_2272
BABT: DK49_2282
BABB: DK48_2517
BABU: DK53_2960
BABS: DK51_2448
BABC: DO78_2097
BMS: BRA0183
BSZ: DK67_2204
BOV: BOV_A0164
BCS: BCAN_B0183(dkgA)
BCAR: DK60_3057
BCAS: DA85_11375
BMR: BMI_II180
BPP: BPI_II181
BPV: DK65_2290
BJA: blr2609
BRA: BRADO2128(dkgB)
BBT: BBta_2445(dkgB)
BRO: BRAD285_4336(dkgB) BRAD285_5125(dkgB)
RPA: RPA4297
RPD: RPD_3895
RPE: RPE_4151
OCG: OCA5_c22570(dkgB)
OCO: OCA4_c22560(dkgB)
BOS: BSY19_858
VGO: GJW-30_1_03380(dkgB)
XAU: Xaut_2717
SNO: Snov_3176
MEA: Mex_1p2002(dkgA)
MDI: METDI2790(dkgA)
MEX: Mext_2023
MCH: Mchl_2300
MPO: Mpop_1985
MNO: Mnod_0968
MOR: MOC_6040
META: Y590_09660
MAQU: Maq22A_c27590(ara1)
PHL: KKY_2116
MMED: Mame_00065(dkgB_1) Mame_04770(dkgB_2) Mame_04780(dkgB_3)
RSP: RSP_2314
JAN: Jann_2582
RDE: RD1_0511(dkgB)
RLI: RLO149_c040950(dkgB)
OAR: OA238_160p1090(dkgB)
MALG: MALG_04936
ROH: FIU89_04770(dkgB)
MARU: FIU81_10110(dkgB)
HBA: Hbal_1978
ZMO: ZMO1673
ZMN: Za10_1545
ZMM: Zmob_1467
ZMB: ZZ6_1443
ZMI: ZCP4_1488
SPHM: G432_02620
STAX: MC45_15150
SPAN: AWL63_10315(dkgB)
ELI: ELI_01980
GOX: GOX0644
GOH: B932_0735
ACR: Acry_1306
GXY: GLX_14490
GXL: H845_2721
KEU: S101446_02031(dkgA)
ASZ: ASN_151(dkgB) ASN_2570
RRF: F11_01455
TMO: TMO_1415(dkgB)
PGV: SL003B_1813(yafB)
BBAT: Bdt_3557
BAML: BAM5036_2332(yvgN)
BAO: BAMF_2496(dhgR)
BACP: SB24_16690
SAV: SAV2200
SAW: SAHV_2184
SAM: MW2127
SAS: SAS2101
SAR: SAR2290
SAC: SACOL2192
SAE: NWMN_2104
SAD: SAAV_2260
SUZ: MS7_2222
SUG: SAPIG2260
SAUA: SAAG_00035
SAUS: SA40_1954
SAUU: SA957_2038
SAUG: SA268_2109
SAUF: X998_2187
SAB: SAB2080c
SAUB: C248_2240
SAUC: CA347_2287
SAUR: SABB_01461
SAUI: AZ30_11640
SAUD: CH52_07950
SAMS: NI36_10865
SPAS: STP1_1255
SSCH: LH95_05640
SSCZ: RN70_05825
SAGQ: EP23_03970
SDP: NCTC12225_01384(dkgB)
LMOE: BN418_3074
LMOB: BN419_3086
LMOD: LMON_2608
LMOW: AX10_07080
LMR: LMR479A_2727(yvgN)
LMOM: IJ09_11780
LMOG: BN389_25520(P100_11E)
LMP: MUO_12950
LMOX: AX24_10970
LMQ: LMM7_2638
LMS: LMLG_1210
LMOK: CQ02_13195
LSG: lse_2292
LIV: LIV_2297
PPOL: X809_04850
PRI: PRIO_5630(yvgN3)
AAD: TC41_0057
LLC: LACR_1361
LLR: llh_6885
LLW: kw2_1145
SMJ: SMULJ23_1314(yvgN3)
SMUA: SMUFR_0592
SUB: SUB0903
SSR: SALIVB_0444(p100_11E)
STJ: SALIVA_0428(p100_11E)
SMN: SMA_1204
SIF: Sinf_1109
SANG: SAIN_1044(ara1)
SLU: KE3_1171
LPL: lp_2803
LJO: LJ_1167
LJH: LJP_0993c
LSL: LSL_0147
LSI: HN6_00126
LBU: LBUL_1768
LDL: LBU_1547
LGA: LGAS_0995
LRE: Lreu_1898
LRF: LAR_1780
LRU: HMPREF0538_21109(akr5f)
LHL: LBHH_1560
LHH: LBH_1697
LHD: HUO_00515
LRH: LGG_02783(dkgA)
LRG: LRHM_2677
LRL: LC705_02770(dkgA)
LRA: LRHK_2886
LAM: LA2_02950
LBH: Lbuc_0218
LAE: LBAT_1511
PPE: PEPE_0075
PPEN: T256_00380
ECAS: ECBG_03073
EMU: EMQU_0348(dkgB) EMQU_1939
THL: TEH_09290
LMM: MI1_04560
LMK: LMES_0889
WKO: WKK_03690
WSO: WSWS_00717(dkgA)
CRN: CAR_c11290(yvgN3)
CBK: CLL_A2112
CBT: CLH_1949
CPAS: Clopa_3561
CLT: CM240_1244(yvgN)
RIX: RO1_26670
ROB: CK5_05730
RTO: RTO_13060
SLP: Slip_0232
TIT: Thit_0703
TPZ: Tph_c21720(yvgN)
TSH: Tsac_1406
VPR: Vpar_1642
AIN: Acin_1054
MPE: MYPE7970(MYPE7970) MYPE9500(MYPE9500)
MHB: MHM_01880(ytbE)
SSYR: SSYRP_v1c08750(ytbE)
SCQ: SCULI_v1c02170(ytbE)
MTV: RVBD_2971
MRA: MRA_2999
MTUR: CFBS_3134
MTD: UDA_2971
MTUC: J113_20705
MTUE: J114_15875
MTX: M943_15305(dkgA)
MTUH: I917_20870
MTUL: TBHG_02901
MTUT: HKBT1_3121
MTUU: HKBT2_3126
MBT: JTY_2988
MBX: BCGT_2811
MAF: MAF_29770
MMIC: RN08_3279
MAVI: RC58_03900(dkgA) RC58_14660 RC58_21230(dkgA)
MAVU: RE97_03905(dkgA) RE97_14685 RE97_21280(dkgA)
MAV: MAV_1085
MUL: MUL_1987
MMI: MMAR_1744
MKN: MKAN_23705(dkgA)
MHAD: B586_15550
MVA: Mvan_1769
MGI: Mflv_4697
MVQ: MYVA_1510
MHAS: MHAS_00967
ASD: AS9A_0862(dkgA)
CGL: NCgl2277(Cgl2359)
CGB: cg2591(dkgA)
CGU: WA5_2277(DkgA)
CGT: cgR_2242
CGM: cgp_2591(dkgA)
CGJ: AR0_11300
CJK: jk0430
CUR: cu1549
CPL: Cp3995_0620(dkgA)
CPP: CpP54B96_0621(dkgA)
CPZ: CpPAT10_0610(dkgA)
COR: Cp267_0638(dkgA)
COD: Cp106_0594(dkgA)
COS: Cp4202_0604(dkgA)
CPSE: CPTA_01159
CPSU: CPTB_00373
CPSF: CPTC_01149
CRD: CRES_0342(dkgA)
CUN: Cul210932_0687(dkgA)
CUS: CulFRC11_0656(dkgA)
CUQ: Cul210931_0656(dkgA)
CUZ: Cul05146_0705(dkgA)
CUJ: CUL131002_0665(dkgA)
CVA: CVAR_0641
COA: DR71_639
CCJ: UL81_03565(dkgB) UL81_08935(dkgA)
CSP: WM42_0593 WM42_1978(dkgA)
CPHO: CPHO_09170
CAQU: CAQU_03605
NFA: NFA_6720
NCY: NOCYR_0689(dkgA)
ROP: ROP_15360 ROP_50880(dkgA)
GBR: Gbro_3547
GOR: KTR9_4584
TPR: Tpau_0861
SCO: SCO6551(SC4B5.01c)
SCT: SCAT_p0714(yvgN)
SALS: SLNWT_0431
SLD: T261_1645
SAMB: SAM23877_0853(dkgB) SAM23877_6253(dkgA)
SPRI: SPRI_1275
SLE: sle_12320(sle_12320) sle_65490(sle_65490)
SFK: KY5_6893c
KSK: KSE_28970
TWH: TWT_016
TWS: TW016(dkgA)
MOO: BWL13_00536(dkgB) BWL13_02818(dkgA)
MLV: CVS47_02007(dkgA) CVS47_02661(dkgB)
AAI: AARI_05170(dkgA) AARI_08870(dkgA) AARI_17510(dkgA)
KRH: KRH_00260(dkgA) KRH_15980(dkgB)
IDO: I598_2147
PAC: PPA2129
PACC: PAC1_10830
PACH: PAGK_2027
CACN: RN83_10880
PFR: PFREUD_01600(dkgA) PFREUD_03160(PF2369)
NCA: Noca_2688
NDK: I601_0950
KFL: Kfla_4692
MGG: MPLG2_0021(dkgA) MPLG2_2791(yvgN)
NDA: Ndas_3534
STRR: EKD16_22500(morA)
TCU: Tcur_1587
SRO: Sros_7952
FAL: FRAAL1875(dkgA)
NML: Namu_4383
MMAR: MODMU_5439(dkgA)
AMD: AMED_6780
PDX: Psed_5591
PSEE: FRP1_28380
PSEH: XF36_00590
PAUT: Pdca_60210
SESP: BN6_26140
ALO: CRK56180
ACTN: L083_7354
CAI: Caci_1160
TPYO: X956_00250(dkgA)
TBW: NCTC13354_01010(dkgA)
BLJ: BLD_1002(akrA2)
BLN: Blon_0442
BLON: BLIJ_0450
BLF: BLIF_0354
BLL: BLJ_0420
BLB: BBMN68_1017(akrA2)
BLM: BLLJ_0358
BLG: BIL_15110
BLA: BLA_0059
BANL: BLAC_00290
BANM: EN10_00350
BBP: BBPR_0382 BBPR_0520(dkgV)
BBF: BBB_0361(dkgA) BBB_0499(dkgA)
BBRU: Bbr_0424 Bbr_1294(dkgV)
BBRS: BS27_0425 BS27_1318(dkgV)
BCOR: BCOR_0310
BKS: BBKW_1645
BCAT: BBCT_1442
BPSP: AH67_00320
BPSC: BBPC_1548
GVG: HMPREF0421_20375(dkgB)
SIJ: SCIP_0226
CWO: Cwoe_0084
CYI: CBM981_2178(dkgA)
GLJ: GKIL_2589(dkgA)
RCA: Rcas_1051
HAU: Haur_0361
ATM: ANT_07630
DGE: Dgeo_0160
DSW: QR90_09505(dkgB)
DCH: SY84_07475(dkgB)
DAB: AUC44_14750(dkgB)
DEIN: DAAJ005_07700(dkgB)
AMU: Amuc_1800
BPO: BP951000_0611(dkgA)
LBA: Lebu_1439
TAI: Taci_1641
GBA: J421_1757
BTHO: Btheta7330_01836(yvgN)
BCEL: BcellWH2_04682(yvgN)
AFD: Alfi_3237
ASH: AL1_06540
RMR: Rmar_0166
CPI: Cpin_3785
MGOT: MgSA37_00872(yvgN)
FJG: BB050_04007(yvgN)
COC: Coch_1297
CHZ: CHSO_1229(dkgB)
TMW: THMA_1031
TMQ: THMB_1031
TMX: THMC_1031
TRQ: TRQ2_1796
TNA: CTN_1569
TNP: Tnap_1754
TLE: Tlet_1573
DTN: DTL3_1721(yvgN3)
SAAL: L336_0470(yvgN)
MMIL: sm9_1609
MEYE: TL18_06655
HAL: VNG_0467G(yafB)
HSL: OE_1698R
HHB: Hhub_1532
HALH: HTSR_0965
HHSR: HSR6_0996
HMA: pNG7293(yafB) rrnAC1660(yafB-3)
HHI: HAH_0190(yafB1) HAH_2201 HAH_5264(yafB3)
NPH: NP_4562A
NMO: Nmlp_2335
HALL: LC1Hm_0329(ara1) LC1Hm_0380(ara1-2) LC1Hm_2193(ara1-3) LC1Hm_2570(dkgB) LC1Hm_4121(dkgB)
HWA: HQ_1533A
HWC: Hqrw_1634
HME: HFX_0858(yafB) HFX_2284 HFX_2638(dkgB)
HDF: AArcSl_0918(dkgB) AArcSl_3238(dkgB2)
NAT: NJ7G_0899
 » show all
Taxonomy
Reference
1
  Authors
Sonoyama, T. and Kobayashi, K.
  Title
Purification and properties of two 2,5-diketo-D-gluconate reductases from a mutant strain derived from Corynebacterium sp.
  Journal
J Ferment Technol 65:311-317 (1987)
Reference
2  [PMID:3597405]
  Authors
Miller JV, Estell DA, Lazarus RA
  Title
Purification and characterization of 2,5-diketo-D-gluconate reductase from Corynebacterium sp.
  Journal
J Biol Chem 262:9016-20 (1987)
  Sequence
Reference
3  [PMID:10427017]
  Authors
Yum DY, Lee BY, Pan JG.
  Title
Identification of the yqhE and yafB genes encoding two 2, 5-diketo-D-gluconate reductases in Escherichia coli.
  Journal
Appl Environ Microbiol 65:3341-6 (1999)
DOI:10.1128/AEM.65.8.3341-3346.1999
Reference
4
  Authors
Maremonti, M., Greco, G. and Wichmann, R.
  Title
Characterisation of 2,5-diketo-D-gluconic acid reductase from Corynebacterium sp.
  Journal
Biotechnology Letters 18:845-850 (1996)
Reference
5  [PMID:9618487]
  Authors
Khurana S, Powers DB, Anderson S, Blaber M
  Title
Crystal structure of 2,5-diketo-D-gluconic acid reductase A complexed with NADPH  at 2.1-A resolution.
  Journal
Proc Natl Acad Sci U S A 95:6768-73 (1998)
DOI:10.1073/pnas.95.12.6768
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.346
IUBMB Enzyme Nomenclature: 1.1.1.346
ExPASy - ENZYME nomenclature database: 1.1.1.346
BRENDA, the Enzyme Database: 1.1.1.346

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