Entry
Name
farnesol dehydrogenase (NAD+);
NAD+-farnesol dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
(2E,6E)-farnesol:NAD+ 1-oxidoreductase
Reaction(IUBMB)
(2E,6E)-farnesol + NAD+ = (2E,6E)-farnesal + NADH + H+ [RN:
R10412 ]
Reaction(KEGG)
Substrate
Product
Comment
The enzyme from the prune mite Carpoglyphus lactis also acts on geraniol with greater activity [cf. EC
1.1.1.347 , geraniol dehydrogenase (NAD+)]. Unlike EC
1.1.1.216 , farnesol dehydrogenase (NADP+), this enzyme cannot use NADP+ as cofactor.
History
EC 1.1.1.354 created 2013
Pathway
ec00900 Terpenoid backbone biosynthesis
ec00909 Sesquiterpenoid and triterpenoid biosynthesis
ec01110 Biosynthesis of secondary metabolites
Orthology
K15891 NAD+-dependent farnesol dehydrogenase
Genes
CSAT : 104716825 104721483 104729924
PSAT : 127088158 127088159
LANG : 109340006 109343904
PCIN : 129295592 129299085
PXB : 103941079 103949739 103949911
PALZ : 118057850 118057851 118062625
QSU : 112017583 112017584 136061440 136065332
CANN : 107850726 107850727
NTA : 107760928 107771557 107803068
NAU : 109217688 109235514 109235516
APAN : 127257110 127257377
CSIN : 114287572 114292023
CQI : 110696565 110696566 110709081
PSOM : 113346636 113356818
TAES : 123093424 123098702
MFLO : 136535602 136551284
SITA : 101767860 101768265
PVIR : 120647065 120647068 120690899 120691876
PHAI : 112874069 112878075
PAUA : 133911758 133916795
NCOL : 116261978 116262597
SMO : SELMODRAFT_111632 SELMODRAFT_234795
» show all
Taxonomy
Reference
Authors
Noge K, Kato M, Mori N, Kataoka M, Tanaka C, Yamasue Y, Nishida R, Kuwahara Y
Title
Geraniol dehydrogenase, the key enzyme in biosynthesis of the alarm pheromone, from the astigmatid mite Carpoglyphus lactis (Acari: Carpoglyphidae).
Journal
Other DBs
ExPASy - ENZYME nomenclature database: 1.1.1.354