KEGG   ENZYME: 1.1.1.354
Entry
EC 1.1.1.354                Enzyme                                 
Name
farnesol dehydrogenase (NAD+);
NAD+-farnesol dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
(2E,6E)-farnesol:NAD+ 1-oxidoreductase
Reaction(IUBMB)
(2E,6E)-farnesol + NAD+ = (2E,6E)-farnesal + NADH + H+ [RN:R10412]
Reaction(KEGG)
R10412
Substrate
(2E,6E)-farnesol [CPD:C01126];
NAD+ [CPD:C00003]
Product
(2E,6E)-farnesal [CPD:C03461];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
The enzyme from the prune mite Carpoglyphus lactis also acts on geraniol with greater activity [cf. EC 1.1.1.347, geraniol dehydrogenase (NAD+)]. Unlike EC 1.1.1.216, farnesol dehydrogenase (NADP+), this enzyme cannot use NADP+ as cofactor.
History
EC 1.1.1.354 created 2013
Pathway
ec00900  Terpenoid backbone biosynthesis
ec00909  Sesquiterpenoid and triterpenoid biosynthesis
ec01110  Biosynthesis of secondary metabolites
Orthology
K15891  NAD+-dependent farnesol dehydrogenase
Genes
ATHAT4G33360(FLDH)
ALY9305289
CRB17878851
CSAT104716825 104721483 104729924
EUSEUTSA_v10025657mg
BRP103862234
BNA106411435 111207928
BOE106302011
RSZ108848622
THJ104819464
CPAP110815277
CIT102617063
PVY116129855
MINC123228976
TCC18591229
GRA105769201
GHI107905556 107958109
GAB108450623
DZI111315425
EGR104449340
GMX100792747
GSJ114414709
PVUPHAVU_009G064000g
VRA106762372
VAR108343368
VUN114196187
CCAJ109801757
APRC113864806
MTRMTR_3g101500
CAM101492439
LJALj1g3v1649010.1(Lj1g3v1649010.1) Lj1g3v1649010.2(Lj1g3v1649010.2) Lj1g3v2584610.1(Lj1g3v2584610.1)
ADU107460435
AIP107605825
AHF112705833 112766223
LANG109340006 109343904
FVE101307656
RCN112174260 112174457
PPER109949998
PMUM103320321
PAVI110761929
PDUL117634062
MDM103428773
PXB103941079 103949739 103949911
ZJU107420927
MNT21386905
CSV101223178
CMO103493529
BHJ120086060
MCHA111026159
CMAX111481147
CMOS111446335
CPEP111789148
RCU8278896
JCU105633659
HBR110664353
MESC110605974
POP112326478 7472693
PEU105120636 105120638
PALZ118057850 118057851 118062625
JRE108987634
QSU112017583 112017584
QLO115974197 115978079
TWL120009004
VVI100266013
VRI117907572
SLY101264803
SPEN107005370
SOT102604685
CANN107850726 107850727
NTA107760928 107771557 107803068
NSY104212650
NTO104093090 104115889
NAU109217688 109235514 109235516
INI109149773
ITR116021819
SIND105166261
OEU111397266 111409485
EGT105971449
SSPL121754503
HAN110913581
ECAD122607565
LSV111876193 111876194
CCAV112511479
DCR108224131 108224133
CSIN114287572 114292023
BVG104898527
SOE110776702
CQI110696565 110696566 110709081
NNU104610585
MING122070219
TSS122660873
PSOM113346636 113356818
NCOL116261978 116262597
OSA9269735 9272175
DOSAOs03t0184550-01(Os03g0184550)
OBR102707016 102707296
BDI100829741
ATS109735166
TDC119288494 119291687
TAES123093424 123098702
SBI8057655 8082002
ZMA100272889
SITA101767860 101768265
SVS117838560 117838561
PVIR120647065 120647068 120690899 120691876
PHAI112874069 112878075
PDA103701809
EGU105048681
MUS103971350
DCT110101245
PEQ110027609
AOF109848345
ATR18425069
SMOSELMODRAFT_111632 SELMODRAFT_234795
PPP112293999
MBASALGA_3274
PGINFRZ67_16760
MUCMuYL_4365
MUHHYN43_025140
MGKFSB76_26125
MRUBDEO27_027385
MGOSDIU38_028775
 » show all
Reference
1  [PMID:18422649]
  Authors
Noge K, Kato M, Mori N, Kataoka M, Tanaka C, Yamasue Y, Nishida R, Kuwahara Y
  Title
Geraniol dehydrogenase, the key enzyme in biosynthesis of the alarm pheromone, from the astigmatid mite Carpoglyphus lactis (Acari: Carpoglyphidae).
  Journal
FEBS J 275:2807-17 (2008)
DOI:10.1111/j.1742-4658.2008.06421.x
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.354
IUBMB Enzyme Nomenclature: 1.1.1.354
ExPASy - ENZYME nomenclature database: 1.1.1.354
BRENDA, the Enzyme Database: 1.1.1.354

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