KEGG   ENZYME: 1.1.1.371Help
Entry
EC 1.1.1.371                Enzyme                                 

Name
scyllo-inositol 2-dehydrogenase (NADP+);
iolW (gene name)
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
scyllo-inositol:NADP+ 2-oxidoreductase
Reaction(IUBMB)
scyllo-inositol + NADP+ = 2,4,6/3,5-pentahydroxycyclohexanone + NADPH + H+ [RN:R09954]
Reaction(KEGG)
Substrate
scyllo-inositol [CPD:C06153];
NADP+ [CPD:C00006]
Product
2,4,6/3,5-pentahydroxycyclohexanone [CPD:C00691];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
The enzyme, found in the bacterium Bacillus subtilis, has no activity with NAD+ [cf. EC 1.1.1.370, scyllo-inositol 2-dehydrogenase (NAD+)].
History
EC 1.1.1.371 created 2014
Pathway
ec00562  Inositol phosphate metabolism
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K16044  scyllo-inositol 2-dehydrogenase (NADP+)
Genes
ETA: ETA_17660(ydgJ)
EBI: EbC_19670
PLU: plu2375
PLUM: A4R40_11845
PAY: PAU_02122
PTT: VY86_19370
PMR: PMI1302
PMIB: BB2000_1322
PVL: AOB99_08470
PVG: CRN77_13240
PHAU: PH4a_14965
XBO: XBJ1_2311(ydgJ)
XBV: XBW1_2060(ydgJ)
XNE: XNC1_2319(ydgJ)
XNM: XNC2_2237(ydgJ)
XDO: XDD1_2185(ydgJ)
XPO: XPG1_1694(ydgJ)
PSI: S70_00355
PSX: DR96_3217
PRG: RB151_023040(ydgJ)
PHEI: NCTC12003_01955(ydgJ)
PRJ: NCTC6933_01964(ydgJ)
MMK: MU9_2251
ANS: ArsFIN_19550(iolW)
AMAL: I607_18140
AMAE: I876_18515
AMAO: I634_18280
AMAD: I636_18295
AMAI: I635_19140
AMAG: I533_18210
AMAC: MASE_18545
HCH: HCH_04874
CCX: COCOR_03600(ydgJ)
SCL: sce9140
HDI: HDIA_1731(yvaA_1)
PSF: PSE_1871
BSU: BSU33530(yvaA)
BSR: I33_3473
BSL: A7A1_2571
BSH: BSU6051_33530(yvaA)
BSUT: BSUB_03581(iolW)
BSUL: BSUA_03581(iolW)
BSUS: Q433_18400
BSS: BSUW23_16430(yvaA)
BST: GYO_3666
BSO: BSNT_09872(yvaA)
BSQ: B657_33530(yvaA)
BSX: C663_3223(yvaA)
BLI: BL00819(yvaA)
BLD: BLi03572(yvaA)
BLH: BaLi_c36330(yvaA)
BAQ: BACAU_3096(yvaA)
BYA: BANAU_3261(yvaA)
BAMP: B938_15725
BAML: BAM5036_2984(yvaA)
BAMA: RBAU_3203(yvaA)
BAMN: BASU_2989(yvaA)
BAMB: BAPNAU_3268(yvaA)
BAMT: AJ82_17360
BAMY: V529_33330(yvaA)
BMP: NG74_03240(yvaA)
BAO: BAMF_3201(yvaA)
BAZ: BAMTA208_17000(yvaA)
BQL: LL3_03484
BXH: BAXH7_03471(yvaA)
BQY: MUS_3672(yvaA)
BAMI: KSO_003795
BAMC: U471_31860
BAMF: U722_16505
BAN: BA_3655
BAR: GBAA_3655
BAT: BAS3390
BAI: BAA_3684
BANT: A16_36620
BANR: A16R_37060
BANS: BAPAT_3499
BANV: DJ46_2371
BCE: BC3595
BCA: BCE_3615
BCQ: BCQ_3389
BCX: BCA_3688
BNC: BCN_3405
BCF: bcf_17825
BCER: BCK_17270
BTL: BALH_3235
BTT: HD73_3870
BTHI: BTK_19040
BTM: MC28_2745
BTI: BTG_01370
BTW: BF38_4773
BWW: bwei_1360
BMYO: BG05_2434
BMYC: DJ92_562
BMQ: BMQ_2694
BMD: BMD_2681
BMH: BMWSH_2518(yvaA)
BMEG: BG04_5160
BJS: MY9_3401
BACP: SB24_13380
BACB: OY17_18680
BACY: QF06_15110
BACL: BS34A_36590(yvaA)
BALM: BsLM_3363
BEO: BEH_16135
BGY: BGLY_3959(yvaA)
BLR: BRLA_c003300(yvaA)
PLV: ERIC2_c06120(yvaA)
CST: CLOST_0537(ydgJ)
PUF: UFO1_3455
AAXA: NCTC10138_00161(yvaA)
DORI: FH5T_21230
 » show all
Taxonomy
Reference
1  [PMID:20133360]
  Authors
Morinaga T, Ashida H, Yoshida K.
  Title
Identification of two scyllo-inositol dehydrogenases in Bacillus subtilis.
  Journal
Microbiology 156:1538-46 (2010)
DOI:10.1099/mic.0.037499-0
  Sequence
[bsu:BSU33530]
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.371
IUBMB Enzyme Nomenclature: 1.1.1.371
ExPASy - ENZYME nomenclature database: 1.1.1.371
BRENDA, the Enzyme Database: 1.1.1.371

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