KEGG   ENZYME: 1.1.1.371
Entry
EC 1.1.1.371                Enzyme                                 

Name
scyllo-inositol 2-dehydrogenase (NADP+);
iolW (gene name)
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
scyllo-inositol:NADP+ 2-oxidoreductase
Reaction(IUBMB)
scyllo-inositol + NADP+ = 2,4,6/3,5-pentahydroxycyclohexanone + NADPH + H+ [RN:R09954]
Reaction(KEGG)
R09954
Substrate
scyllo-inositol [CPD:C06153];
NADP+ [CPD:C00006]
Product
2,4,6/3,5-pentahydroxycyclohexanone [CPD:C00691];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
The enzyme, found in the bacterium Bacillus subtilis, has no activity with NAD+ [cf. EC 1.1.1.370, scyllo-inositol 2-dehydrogenase (NAD+)].
History
EC 1.1.1.371 created 2014
Pathway
ec00562  Inositol phosphate metabolism
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K16044  scyllo-inositol 2-dehydrogenase (NADP+)
Genes
LCQ: 111682085
SERM: CLM71_15180
PANP: PSNIH2_15225
PALH: B1H58_04290
PCD: C2E16_03435
PLU: plu2375
PLUM: A4R40_11845
PAY: PAU_02122
PTT: VY86_19370
PMR: PMI1302
PHAU: PH4a_14965
XBO: XBJ1_2311(ydgJ)
XBV: XBW1_2060(ydgJ)
XNE: XNC1_2319(ydgJ)
XNM: XNC2_2237(ydgJ)
XDO: XDD1_2185(ydgJ)
XPO: XPG1_1694(ydgJ)
PSI: S70_00355
PSX: DR96_3217
PRG: RB151_023040(ydgJ)
PHEI: NCTC12003_01955(ydgJ)
PRJ: NCTC6933_01964(ydgJ)
MMK: MU9_2251
ANS: ArsFIN_19550(iolW)
PMV: PMCN06_0682(ydgJ)
PMP: Pmu_07190(ydgJ)
PMUL: DR93_1482
PDAG: 4362423_00789(ydgJ)
MHT: D648_1130
MHAT: B824_490
MHX: MHH_c06490(yvaA)
MHAE: F382_07580
MHAM: J450_07460
MHAO: J451_08390
MHAL: N220_00495
MHAQ: WC39_13570
MHAY: VK67_13575
MVR: X781_490
MVE: X875_650
APJ: APJL_1202
APA: APP7_1239
ASU: Asuc_0549
BTO: WQG_2440
BTRE: F542_19520
BTRH: F543_21420
BTRA: F544_2010
AVT: NCTC3438_01258(ydgJ)
PAET: NCTC13378_00825(ydgJ_3)
RBD: ALSL_2612
VCS: MS6_A0082
VCI: O3Y_13933
AMAL: I607_18140
AMAE: I876_18515
AMAO: I634_18280
AMAD: I636_18295
AMAI: I635_19140
AMAG: I533_18210
AMAC: MASE_18545
AAUS: EP12_18975
SALH: HMF8227_01125(iolW)
PIN: Ping_1244
MYA: MORIYA_0569(ydgJ)
CJA: CJA_1274
CBU: CBU_0679
CBD: CBUD_0692
CBG: CbuG_1324
CBC: CbuK_1576
GAI: IMCC3135_18695(iolW_3)
HCH: HCH_04874
OCE: GU3_02050
CHJ: NCTC10426_02228(ydgJ)
BMAL: DM55_1128
BMAE: DM78_28
BMAQ: DM76_1105
BMAI: DM57_1659
BMAF: DM51_2608
BMAZ: BM44_294
BMAB: BM45_2908
BPSE: BDL_2020
BPSM: BBQ_3480
BPSU: BBN_66
BPSD: BBX_412
BPK: BBK_1505
BPSH: DR55_1147
BPSA: BBU_2178
BUT: X994_2743
BTE: BTH_I3257
BTQ: BTQ_3197
BTJ: BTJ_2506
BTZ: BTL_443
BTV: BTHA_347
BTHE: BTN_942
BTHM: BTRA_624
BTHA: DR62_1114
BTHL: BG87_626
BVE: AK36_615
BCN: Bcen_2907
BCJ: BCAL0077
BCEW: DM40_921
BAM: Bamb_0135
BMU: Bmul_0145
BMK: DM80_1547
BMUL: NP80_273
BCT: GEM_0139
BCED: DM42_1630
BDL: AK34_2938
BCON: NL30_18760
BLAT: WK25_01970
BTEI: WS51_11550
BSEM: WJ12_00765
BPSL: WS57_13700
BMEC: WJ16_00735
BGU: KS03_1014
BUK: MYA_0145
BXB: DR64_2238
BPH: Bphy_3001
BFN: OI25_1567
CABA: SBC2_35310(ydgJ)
JAG: GJA_4659(ydgJ)
CFU: CFU_1393
CARE: LT85_3371
CCX: COCOR_03600(ydgJ)
SCL: sce9140
MSC: BN69_2082
HDI: HDIA_1731(yvaA_1)
PSF: PSE_1871
SPHI: TS85_07995
BSU: BSU33530(yvaA)
BSR: I33_3473
BSL: A7A1_2571
BSH: BSU6051_33530(yvaA)
BSUT: BSUB_03581(iolW)
BSUL: BSUA_03581(iolW)
BSUS: Q433_18400
BSS: BSUW23_16430(yvaA)
BST: GYO_3666
BSO: BSNT_09872(yvaA)
BSQ: B657_33530(yvaA)
BSX: C663_3223(yvaA)
BLI: BL00819(yvaA)
BLD: BLi03572(yvaA)
BLH: BaLi_c36330(yvaA)
BAQ: BACAU_3096(yvaA)
BYA: BANAU_3261(yvaA)
BAMP: B938_15725
BAML: BAM5036_2984(yvaA)
BAMA: RBAU_3203(yvaA)
BAMN: BASU_2989(yvaA)
BAMB: BAPNAU_3268(yvaA)
BAMT: AJ82_17360
BAMY: V529_33330(yvaA)
BMP: NG74_03240(yvaA)
BAO: BAMF_3201(yvaA)
BAZ: BAMTA208_17000(yvaA)
BQL: LL3_03484
BXH: BAXH7_03471(yvaA)
BQY: MUS_3672(yvaA)
BAMI: KSO_003795
BAMC: U471_31860
BAMF: U722_16505
BAN: BA_3655
BAR: GBAA_3655
BAT: BAS3390
BAI: BAA_3684
BANT: A16_36620
BANR: A16R_37060
BANS: BAPAT_3499
BANV: DJ46_2371
BCE: BC3595
BCA: BCE_3615
BCQ: BCQ_3389
BCX: BCA_3688
BNC: BCN_3405
BCF: bcf_17825
BCER: BCK_17270
BTL: BALH_3235
BTT: HD73_3870
BTHI: BTK_19040
BTM: MC28_2745
BTI: BTG_01370
BTW: BF38_4773
BWW: bwei_1360
BMYO: BG05_2434
BMYC: DJ92_562
BMQ: BMQ_2694
BMD: BMD_2681
BMH: BMWSH_2518(yvaA)
BMEG: BG04_5160
BJS: MY9_3401
BACP: SB24_13380
BACB: OY17_18680
BACY: QF06_15110
BACL: BS34A_36590(yvaA)
BALM: BsLM_3363
BEO: BEH_16135
BGY: BGLY_3959(yvaA)
BBEV: BBEV_3068(yvaA)
BSE: Bsel_2933
LMOD: LMON_2235
LMOW: AX10_05090
LMOM: IJ09_14115
LMP: MUO_11080
LMOX: AX24_08695
LMQ: LMM7_2260
LMS: LMLG_2193
LMOK: CQ02_11210
LWE: lwe2175
LSG: lse_2145
LIV: LIV_2148
BLR: BRLA_c003300(yvaA)
PPY: PPE_02354
PPM: PPSC2_12050(yvaA)
PPO: PPM_2306(yvaA)
PPOL: X809_28060
PPOY: RE92_00305
PLV: ERIC2_c06120(yvaA)
PSAB: PSAB_05415
PRI: PRIO_3071
THL: TEH_12250
CML: BN424_705
CBA: CLB_1945
CBH: CLC_1951
CBY: CLM_2221
CBL: CLK_1458
CBB: CLD_2620
CBI: CLJ_B2208
CBF: CLI_2071
CBM: CBF_2057
CBE: Cbei_4841
CBZ: Cbs_4841
CBEI: LF65_05390
AMT: Amet_3602
ASF: SFBM_1118
ASO: SFBmNL_01195(purA1)
CST: CLOST_0537(ydgJ)
TTM: Tthe_0644
TSH: Tsac_1261
PUF: UFO1_3455
AAXA: NCTC10138_00161(yvaA)
MIT: OCO_10130
MIA: OCU_10140
MID: MIP_01666
NFA: NFA_23680
NFR: ERS450000_01731(yvaA)
SBH: SBI_06708
SDV: BN159_5418(ydgJ)
STRE: GZL_05592
SLD: T261_5247
STRM: M444_13640
SAMB: SAM23877_2899(ydgJ)
SPRI: SPRI_4691
SLE: sle_44100(sle_44100)
SRN: A4G23_01900(yvaA)
SMAL: SMALA_2947
SALJ: SMD11_4343
SLX: SLAV_23630(ydgJ)
SRJ: SRO_4628
CMI: CMM_1580
CMS: CMS1723
ART: Arth_1980
ARM: ART_2868
FAL: FRAAL5078
SEN: SACE_1920
AMI: Amir_6241
SESP: BN6_75110
CAI: Caci_1107
HAU: Haur_4048
PLH: VT85_18245(yvaA)
SACI: Sinac_6157
PBOR: BSF38_01752(iolW_1)
AGV: OJF2_11210(yvaA_1)
ACA: ACP_0499
ABAS: ACPOL_5793
BCEL: BcellWH2_01856(yvaA)
PBT: ING2E5B_2131(yvaA)
PMUC: ING2E5A_0437(iolW)
PSAC: PSM36_0225(ydgJ)
CPI: Cpin_1263
FLN: FLA_4116
PHE: Phep_0179
SMIZ: 4412673_01284(ydgJ_1) 4412673_03021(ydgJ_2)
SDJ: NCTC13534_02018(ydgJ_1) NCTC13534_04280(yvaA_1)
MUC: MuYL_3944
MGOT: MgSA37_01442(yvaA)
CHU: CHU_2007(ydgJ)
DFE: Dfer_4956
SLI: Slin_5750
LBY: Lbys_1027
HSW: Hsw_2986
FJO: Fjoh_1166
FJG: BB050_01435(yvaA)
COC: Coch_1736
CBAL: M667_00210
CBAT: M666_00210
EAO: BD94_0688
ELB: VO54_01988(yhhX)
CHZ: CHSO_4248
MARF: CJ739_999
FBA: FIC_01701
KOL: Kole_0677
 » show all
Reference
1  [PMID:20133360]
  Authors
Morinaga T, Ashida H, Yoshida K.
  Title
Identification of two scyllo-inositol dehydrogenases in Bacillus subtilis.
  Journal
Microbiology 156:1538-46 (2010)
DOI:10.1099/mic.0.037499-0
  Sequence
[bsu:BSU33530]
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.371
IUBMB Enzyme Nomenclature: 1.1.1.371
ExPASy - ENZYME nomenclature database: 1.1.1.371
BRENDA, the Enzyme Database: 1.1.1.371

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