KEGG   ENZYME: 1.1.1.374
Entry
EC 1.1.1.374                Enzyme                                 
Name
UDP-N-acetylglucosamine 3-dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
UDP-N-acetyl-alpha-D-glucosamine:NAD+ 3-oxidoreductase
Reaction(IUBMB)
UDP-N-acetyl-alpha-D-glucosamine + NAD+ = UDP-2-acetamido-3-dehydro-2-deoxy-alpha-D-glucopyranose + NADH + H+ [RN:R10785]
Reaction(KEGG)
R10785
Substrate
UDP-N-acetyl-alpha-D-glucosamine [CPD:C00043];
NAD+ [CPD:C00003]
Product
UDP-2-acetamido-3-dehydro-2-deoxy-alpha-D-glucopyranose [CPD:C20849];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
The enzyme from the archaeon Methanococcus maripaludis is activated by KCl (200 mM).
History
EC 1.1.1.374 created 2014
Orthology
K18855  UDP-N-acetylglucosamine 3-dehydrogenase
Genes
MHARL1P08_10365
GCSMUN88_08050
GSMMUN87_10840
PAUNMJA45_15140 MJA45_22485
PHKSK066_06810
PNKAASFL403_07615 AASFL403_15220
PPABKET34_05535 KET34_10385
BCOCBLCOC_00850(iolG_2) BLCOC_22680(iolG_12)
KSLOG809_38395
ACTQOG417_13685
DFODform_01821
SLOMPXH66_15255
MMPMMP0352
MVNMevan_0204
MVOMvol_0228
MTHMTH_875
MMGMTBMA_c12700
MWOMWSIV6_1249
MTEEMTTB_05060
METCMTCT_0793
METEtca_00840(iolX)
METZMETMT2_0943
METKFVF72_07180
MTHMFZP57_05940
METJFZP68_00265
MSTMsp_1333
METBAW729_08855
MEISPXD04_00515
MRUmru_1747
MSIMsm_0882
MEBAbm4_0457
MMILsm9_1833
MEYETL18_08545
MOLYLM1_1201
MAROMarbSA_18410
METVK4897_07085
MELMetbo_2341
MEWMSWAN_0318 MSWAN_1278
METHMBMB1_0357
MFCBRM9_1907
MFIDSM1535_0093
MCUBMCBB_0333
MSUBBK009_11980
METNBK008_07620
METTCIT01_02215
METOCIT02_05040
MEMEHYG87_03670
MFEGGCM10025860_12540
MFVMfer_1207
MKAMK0248
PFUPF0766
PFIPFC_02985
PABPAB0775
PYCTQ32_02955 TQ32_05360
TGATGAM_0389 TGAM_2151
TSITSIB_2031
TBATERMP_01927
THMCL1_0826
TLTOCC_01379
THSTES1_1882 TES1_2038
TGYX802_04125 X802_05770
THVADU37_CDS21840
TCHCHITON_0802
TPIEA7C91_03605
TCEA3L02_07115
TTDA3L14_00415
THYA3L12_02920
THEIK1720_02895 K1720_03050
MBAMbar_A1138
MBYMSBRM_3417
MBWMSBRW_3585
MBARMSBR2_3374
MBAKMSBR3_3343
MACMA_4448(idh)
MMAMM_1122 MM_1153
MMAZMmTuc01_1167 MmTuc01_1203
MMJMSMAS_0150 MSMAS_0181
MMACMSMAC_0156 MSMAC_0186
MVCMSVAZ_0134
MEKMSKOL_0130
MLSMSLAZ_2866
METMMSMTP_0134 MSMTP_0214
MEFMSWH1_0480 MSWH1_2954
MEQMSWHS_0489 MSWHS_2040
MSJMSSAC_4124 MSSAC_4148
MSZMSSIH_3660 MSSIH_3683
MSWMSSIT_3716 MSSIT_3739
MTHRMSTHT_1686
MTHEMSTHC_1603
MHORMSHOH_0208 MSHOH_0233
MFZAOB57_007590
MBUMbur_0122 Mbur_2030
MMETMCMEM_0690
MELOJ7W08_01555
MPYMpsy_0709
MMAVRE476_05175
MSEBRE474_01465
MHZMetho_1797
MEFWF1737_10590
MPDMCP_0765 MCP_0852 MCP_0895
RCIRCIX1923(idhA)
PABIPABY_19410
CMACmaq_0947
 » show all
Reference
1  [PMID:18634748]
  Authors
Namboori SC, Graham DE
  Title
Enzymatic analysis of uridine diphosphate N-acetyl-D-glucosamine.
  Journal
Anal Biochem 381:94-100 (2008)
DOI:10.1016/j.ab.2008.06.034
  Sequence
[mmp:MMP0352]
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.374
IUBMB Enzyme Nomenclature: 1.1.1.374
ExPASy - ENZYME nomenclature database: 1.1.1.374
BRENDA, the Enzyme Database: 1.1.1.374

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