KEGG   ENZYME: 1.1.1.374
Entry
EC 1.1.1.374                Enzyme                                 
Name
UDP-N-acetylglucosamine 3-dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
UDP-N-acetyl-alpha-D-glucosamine:NAD+ 3-oxidoreductase
Reaction(IUBMB)
UDP-N-acetyl-alpha-D-glucosamine + NAD+ = UDP-2-acetamido-3-dehydro-2-deoxy-alpha-D-glucopyranose + NADH + H+ [RN:R10785]
Reaction(KEGG)
R10785
Substrate
UDP-N-acetyl-alpha-D-glucosamine [CPD:C00043];
NAD+ [CPD:C00003]
Product
UDP-2-acetamido-3-dehydro-2-deoxy-alpha-D-glucopyranose [CPD:C20849];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
The enzyme from the archaeon Methanococcus maripaludis is activated by KCl (200 mM).
History
EC 1.1.1.374 created 2014
Orthology
K18855  UDP-N-acetylglucosamine 3-dehydrogenase
Genes
HIAH733_0577(aidA)
PXAKSS93_10470
TDNSuden_0901
SULNFJR47_04075
SULCCVO_05540
CJUC8J_0468
CJICJSA_0474
CJMCJM1_0482
CJSCJS3_0497
CJPA911_02460
CJERH730_03410
CJVMTVDSCj20_0524
CJYQZ67_00514(idhA)
CJQUC78_0491(idhA)
CJLPJ17_02450
CJWPJ18_02510
CJRCJE0611
CJDJJD26997_1431
CJZM635_06885
CJXBN867_05170
CCVCCV52592_0687 CCV52592_0878
CCOCCC13826_0052
CCOCCCON33237_1237
CLACLA_1070
CLRUPTC16701_1040
CLMUPTC16712_1070
CLQUPTC4110_1049
CLNUPTC3659_1283
CLLCONCH_1024
CCOLBN865_15810
CCCG157_06135
CCQN149_0495
CCFYSQ_07325
CCYYSS_02330
CCOIYSU_06335
CCOFVC76_02645(pht4)
CCOOATE51_03196(pht4)
CISCINS_1034
CVOCVOL_1044
CPELCPEL_1174
CAMRCAQ16704_1059
CSMCSUB8521_1235
CSFCSUB8523_1341
CGRACGRAC_0964
CURECUREO_0588
CPINCPIN18020_0407
CCUNCCUN_0149
CAVICAV_0738
CHWA2J15_004560
COJCORN_1137
CRXCRECT_0771
CGEOCGEO_0625
CBLACBLAS_0584
CCORCCORG_1169
CARMCARM_1088
CMUCCMCT_1266
CSHOCSHOW_1277
SULSSdiek1_2139
SULJSJPD1_2063
SULTFA592_02810
AMOLAMOL_2609
HEBRAEBR_2920
NISNIS_1316
DFLDFE_1681
DSADesal_3643
DHYDESAM_20917
DAFDesaf_1501
DASDaes_2344
DPIBN4_11043
DEJAWY79_15310
PPRFDPRO_2915
PSELGM415_08515
DDNDND132_3281
LLUAKJ09_02966
KAIK32_19920
BJUBJ6T_37880
BJPRN69_18370
BRSS23_23370
AOLS58_25400
BRCBCCGELA001_25180
BRADBF49_5729
BICLMTR13_28220
BROBRAD285_2083
BRKCWS35_31495
BOTCIT37_24700
BRQCIT40_21535
BGQX265_14095
BGZXH91_11900
BSYMCIT39_20860
BBETF8237_26775
BARHWN72_32880
BVZBRAD3257_3197
BELBE61_41020
BDGLPJ38_31595
BSEPHAP48_0047240
BQBJ4P68_0006430
RPBRPB_1608
RPCRPC_1434
RPDRPD_1619
RPERPE_1455
RPTRpal_4502
RPXRpdx1_4239
RBKE0H22_09540
NHANham_1304
OCAOCAR_5339
OCGOCA5_c26370
OCOOCA4_c26360
VGOGJW-30_1_02195(afr_2)
TRBHB776_03500
XAUXaut_2339
XDIEZH22_03330
AZCAZC_3960
SNOSnov_2267
STARG3545_00445
ANCGBB76_06215
APRAG3A50_18040
MIVC4E04_13745
RHZRHPLAN_50000
BVRBVIR_931
BLAGBLTE_28750
PSINCAK95_17760
NOHG5V57_15750
PHRC6569_10745
PSTGE8M01_02110
BSBBresu_0332
BRDJL11_03705
BNEDA69_12555
BRGA4249_13795
BRLBZG35_03715
BVCCEP68_08570
BDMEQG53_04385
BRFE4M01_04145
BREVE7T10_01535
BMEDGYM46_07070
BVYNCTC9239_03180(afr)
BNDKWG56_16255
BPONIFE19_16225
BGOEIFJ75_17200
BVITJIP62_08930
BCRBCAH187_A0417
BCQBCQ_0392(idh)
BNCBCN_0339
BIFN288_14990
GSTHW35_13155
BWHA9C19_16895
BSHILGQ02_18810
BCOBcell_0487 Bcell_2264
BHKB4U37_18720
BCIRC2I06_15075
BMQBMQ_2148 BMQ_pBM50021
BMHBMWSH_3099
BMEGBG04_4458
BEOBEH_17540
BHABH1248
BCLABC3439
BLEBleG1_3629
OIHOB2565 OB3421
OCNCUC15_16595 CUC15_16600 CUC15_17090
OCBCV093_17815
GJFM493_10835
ANMGFC28_1033
ANLGFC29_594
AXLAXY_03850
HHDHBHAL_4556
HMNHM131_04365
HLIHLI_14690
VIRX953_15705
VHLBME96_15255
VIGBKP57_04840
VILCFK37_08630
VNECFK40_03840
FPNABE65_006625 ABE65_012115
FARABE41_007665
BSJUP17_02315
BMURABE28_002250
PBUTDTO10_14195
PPSRI6J18_11935
GRCGI584_01520 GI584_05315 GI584_06215 GI584_19200 GI584_22335
POFGS400_12945
NMKCHR53_25430
MEKUHUW50_08230 HUW50_11915 HUW50_24120
MDGK8L98_08710
BLENNCTC4824_01120(afr_4) NCTC4824_01503(ycjS_8) NCTC4824_03784(afr_10)
BVJI5776_16690
BBEVBBEV_3070(gfo)
GAJMY490_08170
MCLMCCL_0358
MACRBHM04_07915
BBEBBR47_17150
BFMBP422_03755
BAGRBA6348_20355
BCHSJNE38_14350
PJDPjdr2_0740
GYMGYMC10_0462 GYMC10_0796 GYMC10_4296
PPMPPSC2_24645(yobV11)
PPOPPM_4897
PPOLX809_41205
PPQPPSQR21_049860
PPOYRE92_12640
PSABPSAB_09135
PGMPGRAT_11170
PODPODO_16500
PAEAR70723_17870
PAEHH70357_19815 H70357_25860
PAEJH70737_16475
PBJVN24_07070 VN24_14570
PRIPRIO_2408 PRIO_6588
PPEOABE82_24935
PNPIJ22_32680
POWIJ21_27590 IJ21_29480
PBVAR543_19185
PXLBS614_29795
PSWUSY83_02095
PIBBBD41_10800 BBD41_12325 BBD41_24035
PKBB4V02_00405 B4V02_07155
PVOPVOR_04618 PVOR_06285
PLWD5F53_08785 D5F53_25625 D5F53_27220
PPSCEHS13_10080 EHS13_11635 EHS13_17605 EHS13_25960
PALBEJC50_25060 EJC50_27970
PPRTET464_19220
PBACHUB98_13165
PRZGZH47_07890 GZH47_22940 GZH47_22945
PLYCGXP70_08500 GXP70_15895 GXP70_21680 GXP70_23470 GXP70_23475
PTRIKDC22_22285
PALOE6C60_1696
PCELHUB94_19970
PALRHGI30_15345
TCOTheco_1685
COHNKCTCHS21_32960
AFXJZ786_01110
KYRCVV65_02505
JEOJMA_32020
SPAEE2C16_10435 E2C16_10480
PANCE2636_12270
NTRB0W44_12110
PABSJIR001_24520
CPRFK7H06_00450
IBUIB211_03157
HHLHalha_0115
CGJAR0_02355
CGQCGLAR1_02220
CAQUCAQU_12170
DLUA6035_12985
SGBWQO_10760
SFASfla_4282
STRPF750_2427
SFISFUL_2169
SCZABE83_25130
SRNA4G23_01675(ligC)
STRTA8713_10185
SNWBBN63_23680
SLKSLUN_13195
SQZFQU76_09405
STIRDDW44_08305
SNKCP967_23255
SFICEIZ62_22245
SGALCP966_12045
SSPODDQ41_06630
SPADDVK44_09095
SCAVCVT27_09560
STSUB7R87_09300
SFBCP974_09425
STRYEQG64_09855
KABB7C62_09650
STRIC7M71_022140
MIOAOA12_05510
MWAE4K62_04845
MLZF6J85_04620
MCHNHCR76_04850 HCR76_14705
MVDAWU67_02005
FRPAX769_02390
AUMAURMO_00440
MALKMalAC0309_2270
SALAESZ53_05720
LTREVS81_11685
LDNH9L06_09150
LINSG7067_04620
MANTBHD05_15450
CHREIE160_09885
ARRARUE_c28330
ARMART_1662
AREAL755_16300
AAQAOC05_10700 AOC05_10795
ARWMB46_11510
ARZAUT26_13180
ARQBWQ92_17935
ARNCGK93_15505
ARXARZXY2_1011
ACRYAC20117_00190
AAGINCTC2676_1_02019(yvaA)
AAUAAur_2677
PUEFV140_14720
PNVJMY29_12805
MLUMlut_09010
MICKB1A86_00004435
BFABfae_21020
BRXBH708_06725
BRVCFK39_02870
BRZCFK38_08430
BSAUDWV08_07955
BRRC1N80_08410
DJJCOP05_03495
LMOIVV02_09915
XYAET471_01745
CETB8281_08765
CCEUCBR64_02500
SKESked_08630
SANWG7063_11260
CEZCBP52_07945
CEJGC089_06110
ARSADJ73_05365
JMEEEW87_010845
PEIH9L10_02100
SERJSGUI_0550
SERWFY030_06165
ORNDV701_03715
ORZFNH13_09315
DCOSAMEA4475696_1941(iolG)
AUSIPK37_14410
GEZFE251_02870
HALTIM660_13985 IM660_14130
PAKHMPREF0675_3149
PAVTIA2EST22_00685
PAXTIA2EST36_00700
PAZTIA2EST2_00685
PAWPAZ_c01480(iolG1)
PADTIIST44_05335
PCNTIB1ST10_00690
PACCPAC1_00740
PACHPAGK_0141
PACNTIA1EST1_00690
CACNRN83_01135
PRAPALO_09950
PRLBCB70_05940
CGRN4412665_00510(iolG)
PPCHMPREF9154_2725
ARUBJ5A65_12725
PBOPACID_04730
AACIASQ49_02475
ACIJJS278_02848(iolX_3)
AJIC0Z10_11955
MPHMLP_25770
MIKFOE78_05145
MICGGJV80_21250
TFLRPIT_00590
TFABW733_06170
TESBW730_16125
TEZBKM78_06410
TLATLA_TLA_01296(iolX_1)
NCANoca_4211
NDKI601_1769(iolG)
PSIMKR76_03360
ACTWF7P10_15775
SROSros_2251 Sros_3076
NOABKM31_36795
NOWGBF35_08315
NGNLCN96_26045
PAUTPdca_01400
STPStrop_1689
SAQSare_1684
MAUMicau_2086
MILML5_2193
MICBMicB006_5143
MTUACSH63_14370
MICHFJK98_13570
MTEMGCE86_03920
MSAGGCM10017556_43520
VMAVAB18032_18210
MCRAID554_03225
ASEACPL_7750
ACTSACWT_7619
AIHAiant_36060
PLABC6361_28965
PLATC6W10_06475
VERHUT12_14395
CAICaci_7629
MCUHMPREF0573_11047
TPYCQ11_05130
TPYOX956_02580
TBWNCTC13354_00626(yvaA)
TPECHLG82_01820
SOOFBF35_07835
ACQAM609_10150
AOSAXE84_07680
ARDAXF14_01715
ACTPB6G06_07780
ACTCCHIBA101_1987
ANEAN27039_1727
AHWNCTC11636_02346(iolG_2)
ACTZCWT12_09385
ASLANCTC11923_02577(ydgJ)
AVCNCTC10951_01534(iolG_2)
AREPID810_02180
AVUBK816_03310
FSLEJO69_11395
WIKH8R18_01655
EKEEK0264_10615
BSOLFSW04_03480
CWOCwoe_5494
EUZDVS28_a1734 DVS28_a3561 DVS28_a4674
DFODform_01821
RRSRoseRS_1135
RCARcas_3975
CHLChy400_4094
CAGCagg_0831
PSUBPelsub_P0631
CAPCLDAP_17300
TBHTbon_02430
TTRTter_2603
CCZCCALI_01909
AMOBHG15A2_41960(gfo_4)
GIMF1728_07995 F1728_26170
GPNPan110_13340(iolG_5) Pan110_38740(ligC_3)
SDYNMal52_34580(ligC_2)
BROCIPI25_12395
ALUSSTSP2_02703(gfo_2)
BHCJFL75_04400
LBILEPBI_I2025
LBFLBF_1972
BHPBHAMNSH16_01135
SULSYO3AOP1_1282
SAFSULAZ_0147
PMXPERMA_0059
TLETlet_0392
PHYAJ81_04690
MPGTheba_1412 Theba_1413
MINFMESINF_2813
DINSelin_0714
NKFNkreftii_002734
MMPMMP0352
MVNMevan_0204
MVOMvol_0228
MTHMTH_875
MMGMTBMA_c12700
METCMTCT_0793
MWOMWSIV6_1249
METEtca_00840(iolX)
METZMETMT2_0943
METKFVF72_07180
MTHMFZP57_05940
METJFZP68_00265
MSTMsp_1333
METBAW729_08855
MRUmru_1747
MSIMsm_0882
MEBAbm4_0457
MMILsm9_1833
MEYETL18_08545
MOLYLM1_1201
MAROMarbSA_18410
MELMetbo_2341
MEWMSWAN_0318 MSWAN_1278
METHMBMB1_0357
MFCBRM9_1907
MFIDSM1535_0093
MCUBMCBB_0333
MSUBBK009_11980
METNBK008_07620
METTCIT01_02215
METOCIT02_05040
MEMEHYG87_03670
MFVMfer_1207
MKAMK0248
AVEArcve_0564
ASTAsulf_00048
PFUPF0766
PFIPFC_02985
PHOPH1882(PH1882)
PABPAB0775
PYNPNA2_0470
PYSPy04_0017
PYCTQ32_02935 TQ32_02955 TQ32_05360
TGATGAM_0389 TGAM_1564 TGAM_2151
TSITSIB_1682 TSIB_2031
TBATERMP_01840 TERMP_01841 TERMP_01927
THEGQS_09545
THMCL1_0826
TLTOCC_01379 OCC_05866
THSTES1_1826 TES1_1827 TES1_1882 TES1_2038
TGYX802_04125 X802_05770
THVADU37_CDS21840
TCHCHITON_0802
TPIEA7C91_03605
TGGA3K92_07375
TCEA3L02_05570 A3L02_07115
TBSA3L01_06705
THHCDI07_06670
TTDA3L14_00415 A3L14_09110
TRLA3L10_06175
THYA3L12_01515 A3L12_02920
PPACPAP_05155
MBAMbar_A1138
MBYMSBRM_3417
MBWMSBRW_3585
MBARMSBR2_3374
MBAKMSBR3_3343
MACMA_4448(idh)
MMAMM_1122 MM_1153
MMAZMmTuc01_1167 MmTuc01_1203
MMJMSMAS_0150 MSMAS_0181
MMACMSMAC_0156 MSMAC_0186
MVCMSVAZ_0134
MEKMSKOL_0130
MLSMSLAZ_2866
METMMSMTP_0134 MSMTP_0214
MEFMSWH1_0480 MSWH1_2954
MEQMSWHS_0489 MSWHS_2040
MSJMSSAC_4124 MSSAC_4148
MSZMSSIH_3660 MSSIH_3683
MSWMSSIT_3716 MSSIT_3739
MTHRMSTHT_1686
MTHEMSTHC_1603
MHORMSHOH_0208 MSHOH_0233
MFZAOB57_007590
MBUMbur_0122 Mbur_1611 Mbur_2030
MMETMCMEM_0690
MELOJ7W08_01555
MPYMpsy_0709
MHZMetho_1797
MPDMCP_0765 MCP_0852 MCP_0895
RCIRCIX1923(idhA)
HALJG9465_10790 G9465_19390
HALIBV210_18885 BV210_19425
HRRHZS55_06580 HZS55_10290
HPELHZS54_07115 HZS54_14840
HLTI7X12_03315 I7X12_06695
HBOHbor_33500 Hbor_33520 Hbor_33530
HAQDU484_07380
HAJDU500_07530
HAERDU502_04940
HRAEI982_08440
HXAHalxa_0452
ACFAciM339_0815
IAGIgag_1264
HBUHbut_1413
PFMPyrfu_1822
PDLPyrde_1941
PYRP186_2329
POGPogu_2396
TNETneu_0084
PYWPYWP30_00095
CMACmaq_0682 Cmaq_0906 Cmaq_0947
TTNTTX_1867
TUZTUZN_1623
VDIVdis_0790
VMOVMUT_1637
TPETpen_0717
THBN186_04940
TCBTCARB_0049
THFMA03_06125
THELIG193_04165
FFOFFONT_0258
NMRNmar_0247
NIRNSED_01150
NIDNPIRD3C_0640
NINNADRNF5_2001
NIWNisw_03700
NCLC5F47_01330
NOXC5F49_01305
NUEC5F50_01600
NIPNsoK4_07620
NCTNMSP_1463
NICDSQ20_01470
CSYCENSYa_1718
NGANgar_c21060
NVNNVIE_007640 NVIE_010090
NEVNTE_02307
TAANMY3_00953(iolG)
NFNNFRAN_1913(iolG)
NCVNCAV_0867
CSUCSUB_C0020 CSUB_C0685
NBVT478_1203
TAHSU86_007900
NIUDSQ19_08920
NDVNDEV_1854
CCAINAS2_1630
KCRKcr_1479
FLTSv326_0005
 » show all
Reference
1  [PMID:18634748]
  Authors
Namboori SC, Graham DE
  Title
Enzymatic analysis of uridine diphosphate N-acetyl-D-glucosamine.
  Journal
Anal Biochem 381:94-100 (2008)
DOI:10.1016/j.ab.2008.06.034
  Sequence
[mmp:MMP0352]
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.374
IUBMB Enzyme Nomenclature: 1.1.1.374
ExPASy - ENZYME nomenclature database: 1.1.1.374
BRENDA, the Enzyme Database: 1.1.1.374

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