KEGG   ENZYME: 1.1.1.377
Entry
EC 1.1.1.377                Enzyme                                 
Name
L-rhamnose 1-dehydrogenase (NADP+)
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
L-rhamnose:NADP+ 1-oxidoreductase
Reaction(IUBMB)
L-rhamnose + NADP+ = L-rhamnono-1,4-lactone + NADPH + H+ [RN:R10788]
Reaction(KEGG)
R10788
Substrate
L-rhamnose [CPD:C00507];
NADP+ [CPD:C00006]
Product
L-rhamnono-1,4-lactone [CPD:C02991];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
The enzyme from the archaeon Thermoplasma acidophilum is part of the non-phosphorylative degradation pathway for L-rhamnose. The enzyme differs in cofactor specificity from EC 1.1.1.173, L-rhamnose 1-dehydrogenase, which is specific for NAD+.
History
EC 1.1.1.377 created 2014
Pathway
ec00051  Fructose and mannose metabolism
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K18337  L-rhamnose 1-dehydrogenase
Genes
QSU: 111990061 112003557 112030403
PPA: PAS_chr4_0338
DHA: DEHA2E01100g
PIC: PICST_50944(DHG2)
PGU: PGUG_03591
CTEN: CANTEDRAFT_113935
CLU: CLUG_02926
CLUS: A9F13_18g00385
CAUR: CJI97_002171
SLB: AWJ20_4952(SPS19)
BNN: FOA43_001971(DHG2)
OPA: HPODL_01987
NCR: NCU09035
NTE: NEUTE1DRAFT102514(NEUTE1DRAFT_102514)
SMP: SMAC_05850
PAN: PODANSg706
TTT: THITE_2111000
MTM: MYCTH_102290
CTHR: CTHT_0045640
MGR: MGG_08318
PPEI: PpBr36_02105
TMN: UCRPA7_3732 UCRPA7_5029
SSCK: SPSK_02647
FGR: FGSG_09882
FPU: FPSE_10199
FVR: FVEG_02597
FOX: FOXG_05543
NHE: NECHADRAFT_37021 NECHADRAFT_41350
TRE: TRIREDRAFT_65588
TRR: M419DRAFT_36736
MAJ: MAA_08254
CMT: CCM_06363
PLJ: VFPFJ_09562
VAL: VDBG_07058
VDA: VDAG_06700
CFJ: CFIO01_07064 CFIO01_09199
CLUP: CLUP02_17412
CHIG: CH63R_09431
ELA: UCREL1_2272 UCREL1_7808
PFY: PFICI_03100 PFICI_06510 PFICI_13970
SSL: SS1G_10326
BFU: BCIN_14g04170
MBE: MBM_02654
PSCO: LY89DRAFT_684259 LY89DRAFT_707448
GLZ: GLAREA_03301
ANI: AN1886.2 AN4186.2
AFM: AFUA_7G04360
ACT: ACLA_006060
NFI: NFIA_025330
AOR: AO090005000123
ANG: ANI_1_132114(An13g00930) ANI_1_256044(An05g02050)
AFV: AFLA_002906
ALUC: AKAW2_20117A(DHG2) AKAW2_81349A
ACHE: ACHE_31306A ACHE_40186A(DHG2)
APUU: APUU_21191A APUU_50081S APUU_60465A(DHG2) APUU_60792A
PCS: Pc21g04410 Pc22g09480
PDP: PDIP_82370
TMF: PMAA_069180
TRG: TRUGW13939_06749 TRUGW13939_09624
ABE: ARB_00929
TVE: TRV_00758
PNO: SNOG_14192(SNOG_14191)
PTE: PTT_09742
BZE: COCCADRAFT_36707
BSC: COCSADRAFT_40878
BOR: COCMIDRAFT_4863
AALT: CC77DRAFT_1054497
ZTR: MYCGRDRAFT_83548
PFJ: MYCFIDRAFT_39072
FFU: CLAFUR5_12021 CLAFUR5_13485
BCOM: BAUCODRAFT_64509
NPA: UCRNP2_3170
TML: GSTUM_00003021001 GSTUM_00009300001
CNE: CNB05760
CNB: CNBB0030
CNG: CNAG_04097
CGI: CGB_A0020C
TASA: A1Q1_01844
PPL: POSPLDRAFT_87849
TVS: TRAVEDRAFT_159063
DSQ: DICSQDRAFT_131032
PCO: PHACADRAFT_247452
SHS: STEHIDRAFT_89569
HIR: HETIRDRAFT_456869
PSQ: PUNSTDRAFT_48714
ADL: AURDEDRAFT_80943
FME: FOMMEDRAFT_81776
GTR: GLOTRDRAFT_53059
ABP: AGABI1DRAFT31987(AGABI1DRAFT_31987)
ABV: AGABI2DRAFT182285(AGABI2DRAFT_182285)
MPR: MPER_11191
MRR: Moror_17215
MORE: E1B28_000966
SCM: SCHCO_02610587(SCHCODRAFT_02610587)
CPUT: CONPUDRAFT_86700
SLA: SERLADRAFT_467003
UMA: UMAG_11693
PFP: PFL1_03743
PLUM: A4R40_11700
PFN: HZ99_04550
PTV: AA957_01200
PAZO: AYR47_21440
PFX: A7318_11935
PYM: AK972_2741
PEZ: HWQ56_16160
PTRT: HU722_0013875
AVN: Avin_09160
AVL: AvCA_09160
AVD: AvCA6_09160
ABER: BSR55_00550
HEL: HELO_4213(rhaD)
HHU: AR456_20000
HBH: E4T21_09965
SALN: SALB1_2836
AMAH: DLM_0709
AQS: DKK66_01665
BCM: Bcenmc03_6233
BCH: Bcen2424_6635
BAM: Bamb_3400
BAC: BamMC406_1208
BPYR: ABD05_31635
BSEM: WJ12_16075
BUG: BC1001_3863
BGF: BC1003_5545
BYI: BYI23_B007530
BUE: BRPE67_BCDS10610
BUQ: AC233_21650
BGP: BGL_2c06950(fabG4)
BPLA: bpln_2g07800
BUM: AXG89_17635
BUI: AX768_27415
BURK: DM992_37155
BXE: Bxe_B1031
BXB: DR64_6352
BPH: Bphy_3467
BGE: BC1002_4237
BPX: BUPH_00437
BPY: Bphyt_5688
BFN: OI25_6825
BCAI: K788_0008513
PSPW: BJG93_25610
PARA: BTO02_31830
PARB: CJU94_23860
PHS: C2L64_22530
PTER: C2L65_25100
PGP: CUJ91_21880
PCJ: CUJ87_23065
PTS: CUJ90_29530
PMEG: FNZ07_09785
PTRO: G5S35_23015
PGIS: I6I06_24295
PACP: FAZ97_21155
PACS: FAZ98_17345
PEW: KZJ38_34630
PDIO: PDMSB3_2081.1(rhaD)
PBRY: NDK50_27200
PPUL: RO07_24905
PNR: AT302_22510
CABA: SBC2_60260
BUO: BRPE64_BCDS05710
VPD: VAPA_2c00520
KIA: G8A07_05020
MALI: EYF70_08165
MUM: FCL38_10600
MPLI: E1742_17255
MESP: C1M53_17345
RPOD: E0E05_15250
SMK: Sinme_6600
SMQ: SinmeB_6525
SMX: SM11_pC0375
SMI: BN406_03597(fabG1)
SMEL: SM2011_a0335
SMER: DU99_18905
SMD: Smed_5223
SIX: BSY16_5763
EAH: FA04_28460
AGR: AGROH133_14217
ATF: Ach5_46630
BOF: FQV39_05180
CSE: Cseg_1768 Cseg_2740
CFH: C1707_14155
BSB: Bresu_2867
BRD: JL11_06990
BRG: A4249_07690
BREV: E7T10_08375
BND: KWG56_07380
AEX: Astex_2133
PTP: RCA23_c23450(fabG4)
HBA: Hbal_2755
STAX: MC45_07230 MC45_07285
SPHI: TS85_02230
SSAN: NX02_22785
SNJ: A7E77_11680
SMY: BJP26_16645
SPAN: AWL63_05960
SKR: BRX40_01540
SPLM: BXU08_17995
SPHC: CVN68_10795
SARI: H5J25_00325
SSUA: FPZ54_00310
SBIN: SBA_ch1_06520
SCAB: LZK98_19645
SNOS: K8P63_02120
SPHR: BSY17_3168
SYA: A6768_21720
SPYG: YGS_C1P2522
BLAS: BSY18_1707
BFW: B5J99_17915
SPHS: ETR14_07025
TFV: IDJ81_03365
ABG: Asbog_01342
ROS: CTJ15_21290
NAO: Y958_05065
NCB: C0V82_24320
PPSC: EHS13_31275
PBK: Back11_16610(fabG_2)
CHEB: HH215_02220 HH215_18270
PAUT: Pdca_50300(fabG_11)
PMAD: BAY61_19440
ATL: Athai_30200
ASER: Asera_44360
SACI: Sinac_3785
TAC: Ta0747
TVO: TVG0436799(TVG0436799)
FAC: FACI_IFERC01G0497
 » show all
Reference
1  [PMID:22481639]
  Authors
Kim SM, Paek KH, Lee SB
  Title
Characterization of NADP+-specific L-rhamnose dehydrogenase from the thermoacidophilic Archaeon Thermoplasma acidophilum.
  Journal
Extremophiles 16:447-54 (2012)
DOI:10.1007/s00792-012-0444-1
  Sequence
[tac:Ta0747]
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.377
IUBMB Enzyme Nomenclature: 1.1.1.377
ExPASy - ENZYME nomenclature database: 1.1.1.377
BRENDA, the Enzyme Database: 1.1.1.377

  All links  
Pathway (6)   
   KEGG PATHWAY (6)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG REACTION (1)   
   KEGG RCLASS (1)   
Gene (427)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (249)   
   KEGG MGENES (98)   
   RefGene (79)   
Protein sequence (105)   
   UniProt (96)   
   SWISS-PROT (1)   
   RefSeq(pep) (8)   
DNA sequence (19)   
   RefSeq(nuc) (10)   
   GenBank (5)   
   EMBL (4)   
Protein domain (3)   
   InterPro (3)   
All databases (567)   

Download RDF
DBGET integrated database retrieval system