KEGG   ENZYME: 1.1.1.385Help
Entry
EC 1.1.1.385                Enzyme                                 

Name
dihydroanticapsin dehydrogenase;
BacC;
ywfD (gene name)
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
L-dihydroanticapsin:NAD+ oxidoreductase
Reaction(IUBMB)
L-dihydroanticapsin + NAD+ = L-anticapsin + NADH + H+ [RN:R10917]
Reaction(KEGG)
Substrate
L-dihydroanticapsin [CPD:C20940];
NAD+ [CPD:C00003]
Product
L-anticapsin [CPD:C20941];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
The enzyme, characterized from the bacterium Bacillus subtilis, is involved in the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin.
History
EC 1.1.1.385 created 2015
Pathway
ec00998  Biosynthesis of secondary metabolites - other antibiotics
ec01100  Metabolic pathways
ec01130  Biosynthesis of antibiotics
Orthology
K19548  dihydroanticapsin dehydrogenase
Genes
ZAL: AZF00_02525
PARA: BTO02_29060
SMI: BN406_06775
RHI: NGR_b19870
SAME: SAMCFNEI73_pC1591(bacC)
REP: IE4803_CH03677
RUA: D1823_09010
SEDI: EBB79_03440
SPHB: EP837_03750
RDI: CMV14_16680
BSU: BSU37720(bacC)
BSR: I33_3920
BSL: A7A1_0191
BSH: BSU6051_37720(bacC)
BSUT: BSUB_04008(bacC)
BSUL: BSUA_04008(bacC)
BSUS: Q433_20775
BSS: BSUW23_18630(bacC)
BST: GYO_4158
BSO: BSNT_10430(ywfD)
BSQ: B657_37720(bacC)
BSX: C663_3677(bacC)
BAY: RBAM_034910(bacC)
BAQ: BACAU_3520(bacC)
BYA: BANAU_3673(bacC)
BAMP: B938_17915(bacC)
BAML: BAM5036_3421(bacC)
BAMA: RBAU_3629(bacC)
BAMN: BASU_3405(bacC)
BAMB: BAPNAU_3687(bacC)
BAMT: AJ82_19700
BAMY: V529_37630(bacC)
BMP: NG74_03666(gdhIV_2)
BAO: BAMF_3605(bacC)
BAZ: BAMTA208_19090(bacC)
BQL: LL3_03916(bacC)
BXH: BAXH7_03908(bacC)
BQY: MUS_4150(bacC3)
BAMI: KSO_001605
BAMC: U471_36360
BAMF: U722_18650
BPU: BPUM_3422
BPUM: BW16_18170
BPUS: UP12_17615
BJS: MY9_3863
BACW: QR42_17170
BACP: SB24_11240
BACB: OY17_01120
BACY: QF06_17300
BACL: BS34A_40900(bacC)
BALM: BsLM_3802
PPY: PPE_00548
PPM: PPSC2_03030(fabG3)
PPO: PPM_0548(fabG3)
PPOL: X809_02505
PPQ: PPSQR21_005830(fabG)
PPOY: RE92_08905
PSAB: PSAB_12355
MHAS: MHAS_02975(xecD)
RRT: 4535765_02278(ycdF_2)
STRM: M444_35575
AOI: AORI_3585
SESP: BN6_36930
PBOR: BSF38_00344(xecD)
ABAS: ACPOL_4032
 » show all
Taxonomy
Reference
1  [PMID:23317005]
  Authors
Parker JB, Walsh CT
  Title
Action and timing of BacC and BacD in the late stages of biosynthesis of the dipeptide antibiotic bacilysin.
  Journal
Biochemistry 52:889-901 (2013)
DOI:10.1021/bi3016229
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.385
IUBMB Enzyme Nomenclature: 1.1.1.385
ExPASy - ENZYME nomenclature database: 1.1.1.385
BRENDA, the Enzyme Database: 1.1.1.385

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