KEGG   ENZYME: 1.1.1.386Help
Entry
EC 1.1.1.386                Enzyme                                 

Name
ipsdienol dehydrogenase;
IDOLDH
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
(R)-ipsdienol:NAD(P)+ oxidoreductase
Reaction(IUBMB)
(R)-ipsdienol + NAD(P)+ = ipsdienone + NAD(P)H + H+ [RN:R10918 R10919]
Reaction(KEGG)
Substrate
(R)-ipsdienol [CPD:C20943];
NAD+ [CPD:C00003];
NADP+ [CPD:C00006]
Product
ipsdienone [CPD:C20944];
NADH [CPD:C00004];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
The enzyme is involved in pheromone production by the pine engraver beetle, Ips pini.
History
EC 1.1.1.386 created 2015
Pathway
ec00902  Monoterpenoid biosynthesis
ec01110  Biosynthesis of secondary metabolites
Orthology
K20142  ipsdienol dehydrogenase
Reference
1  [PMID:22101251]
  Authors
Figueroa-Teran R, Welch WH, Blomquist GJ, Tittiger C
  Title
Ipsdienol dehydrogenase (IDOLDH): a novel oxidoreductase important for Ips pini pheromone production.
  Journal
Insect Biochem Mol Biol 42:81-90 (2012)
DOI:10.1016/j.ibmb.2011.10.009
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.386
IUBMB Enzyme Nomenclature: 1.1.1.386
ExPASy - ENZYME nomenclature database: 1.1.1.386
BRENDA, the Enzyme Database: 1.1.1.386

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