KEGG   ENZYME: 1.1.1.388
Entry
EC 1.1.1.388                Enzyme                                 
Name
glucose-6-phosphate dehydrogenase (NAD+);
Glc6PDH;
azf (gene name);
archaeal zwischenferment
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
D-glucose-6-phosphate:NAD+ 1-oxidoreductase
Reaction(IUBMB)
D-glucose 6-phosphate + NAD+ = 6-phospho-D-glucono-1,5-lactone + NADH + H+ [RN:R10520]
Reaction(KEGG)
R10520 > R10907
Substrate
D-glucose 6-phosphate [CPD:C00092];
NAD+ [CPD:C00003]
Product
6-phospho-D-glucono-1,5-lactone [CPD:C01236];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
The enzyme catalyses a step of the pentose phosphate pathway. The enzyme from the archaeon Haloferax volcanii is specific for NAD+. cf. EC 1.1.1.363, glucose-6-phosphate dehydrogenase [NAD(P)+] and EC 1.1.1.49, glucose-6-phosphate dehydrogenase (NADP+).
History
EC 1.1.1.388 created 2015
Pathway
ec00030  Pentose phosphate pathway
Orthology
K19243  NAD+ dependent glucose-6-phosphate dehydrogenase
Genes
SMACSMDB11_4230
SMWSMWW4_v1c01330
SPESpro_0125
SRRSerAS9_0085
SRLSOD_c00800
SRYM621_00395
SPLYQ5A_000425(udh)
SRSSerAS12_0085
SRASerAS13_0084
SMAFD781_0092
SLQM495_00425
SERFL085_05040
SERSSERRSCBI_00530
SFWWN53_08960
SFGAV650_01965
SRZAXX16_0430
SERMCLM71_00560
SQUE4343_15670
SFJSAMEA4384070_0088
SSURATE40_021335
SURIJ0X03_23415
SRHZFO014_09445
SENPKHA73_22670
SFOZ042_12665
GQUAWC35_10960
PAGCBEE12_20140
VNIVIBNI_B0433
VSHBSZ05_17150
LABPFJ695_05645
RUAD1823_00645
PHQD1820_15470
BLIBL00020(ytbQ)
BLDBLi03170(ytbQ)
BLHBaLi_c32420(ytbQ)
BSONS101395_01332
BPUBPUM_2667
BPUMBW16_14380
BPUSUP12_13645
BXIBK049_13705
BALTCFN77_14320
BSAFBSL056_15045
BACWQR42_13450
OIHOB2094
JEPBW721_01640
JDABW727_101137(udh)
JARG7057_00785
BFABfae_19740
BRXBH708_05895
BRVCFK39_02265
BGGCFK41_06745
BRZCFK38_09045
BSAUDWV08_07345
BRRC1N80_08935
ARSADJ73_06060
JLIEXU32_08155
JMEEEW87_000815
SERWFY030_05825
ORNDV701_11445
GEZFE251_10790
RSUALQF12_03265
MICGGJV80_12200
TFLRPIT_03130
TEZBKM78_12175
TLATLA_TLA_02453(udh_2)
BRTJ4N02_06995
VERHUT12_13150
TROtrd_1948
KBSEPA93_05700
PLONPla110_18890(fcl_3)
HBSIPV69_22805
HALVNG_0128C
HSLOE_1209F
HDLHALDL1_04035
HHBHhub_1317
HAGSJT689_01935
HABOJRZ79_00460
HNOLT974_01500
HLULT972_12330
HANRLJ422_00595
HJEHacjB3_14685
HALHHTSR_1773
HHSRHSR6_1839
HSUHLASF_0479
HSFHLASA_0476
SALRFQU85_02990
HALREFA46_005210 EFA46_010660 EFA46_010735
HARAAArcS_2737(wcaG11)
HAADMW046_08820
HALXM0R89_08310
HAXZM0R88_08495
HMArrnAC2305
HHIHAH_2759
HHNHISP_14025
HABSG26_03090 SG26_06305
HTABVU17_13435
HALJG9465_22030 G9465_23975
HSINKDQ40_15555
NPHNP_0308A(azf)
NMONmlp_1075
NHOHWV23_07375
NSALHWV07_10755
HMUHmuk_0576
HALZE5139_06035
HALLLC1Hm_3107
HAZPGBQ70_06030
HALIBV210_06955
HSNDV733_11575
HDSHSR122_1890(wcaG3)
HRRHZS55_00310 HZS55_21660
HPELHZS54_00365 HZS54_10485 HZS54_25135
HLTI7X12_13175 I7X12_14960
HARCHARCEL1_00695
HDOMUK72_03965
HWAHQ_1135A(azf)
HWCHqrw_1170(azf)
HVOHVO_0511(azf)
HMEHFX_0485
HGIABY42_02395 ABY42_15930 ABY42_18635
HALEG3A49_02635 G3A49_06695
HBOHbor_27280
HAQDU484_01385 DU484_06630
HAJDU500_01935 DU500_06900
HAERDU502_17440
HRAEI982_13605
HLMDV707_13470
HALMFCF25_06995 FCF25_09350
HLAHlac_0117 Hlac_2457
HALPDOS48_00600
HALBEKH57_11815
HEZZEO776_00480
HALQHrr1229_006340
HSSJ7656_00745
HSAIHPS36_06255
HAZZKI388_14110
SRUBC2R22_02330 C2R22_03520 C2R22_19640 C2R22_24195
HAEhalTADL_0298
HALNB4589_010180 B4589_012900
HALGHUG10_05530 HUG10_15360 HUG10_15910 HUG10_17945 HUG10_20285
HALUHUG12_18245
HMPK6T50_13120
HREK6T36_13035
HRMK6T25_03630
HACBHbl1158_04965
HDFAArcSl_0115 AArcSl_0416
HAHHalar_2838 Halar_3481
HTUHtur_0435 Htur_0833 Htur_4212 Htur_4433
HDABB347_12925
HSALJMJ58_07010 JMJ58_23600
HLOJ0X27_16360
HAKZJ0X25_08735
NMGNmag_2247(azf)
HXAHalxa_0384 Halxa_1805
NATNJ7G_4277
NPENatpe_3416
NVRFEJ81_16400 FEJ81_22085
NPLFGF80_15460
NAYHYG81_12865 HYG81_23160
HALYHYG82_13630 HYG82_18190
HJTDVR14_07215
NGENatgr_1320
HRUHalru_2600
NOUNatoc_0279
SALIL593_05140 L593_11535
SAIMK0C01_00340
HLRHALLA_02775 HALLA_04445 HALLA_04630 HALLA_06030
HLCCHINAEXTREME02945
NAJB1756_06410
NAGAArcMg_0155
NANAArc1_0157
NBGDV706_08395
NASGCU68_03710
SAWLNGM29_04355
NCONLC1Nh_0694
 » show all
Reference
1  [PMID:25836736]
  Authors
Pickl A, Schonheit P
  Title
The oxidative pentose phosphate pathway in the haloarchaeon Haloferax volcanii involves a novel type of glucose-6-phosphate dehydrogenase - The archaeal Zwischenferment.
  Journal
FEBS Lett 589:1105-11 (2015)
DOI:10.1016/j.febslet.2015.03.026
  Sequence
[hvo:HVO_0511]
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.388
IUBMB Enzyme Nomenclature: 1.1.1.388
ExPASy - ENZYME nomenclature database: 1.1.1.388
BRENDA, the Enzyme Database: 1.1.1.388

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