KEGG   ENZYME: 1.1.1.402Help
Entry
EC 1.1.1.402                Enzyme                                 

Name
D-erythritol 1-phosphate dehydrogenase;
eryB (gene name)
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
D-erythritol-1-phosphate 2-oxidoreductase
Reaction(IUBMB)
D-erythritol 1-phosphate + NADP+ = D-erythrulose 1-phosphate + NADPH + H+ [RN:R11341]
Reaction(KEGG)
Substrate
D-erythritol 1-phosphate [CPD:C21294];
NADP+ [CPD:C00006]
Product
D-erythrulose 1-phosphate [CPD:C21285];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
The enzyme, characterized from the pathogenic bacterium Brucella abortus, which causes brucellosis in livestock, participates in erythritol catabolism.
History
EC 1.1.1.402 created 2016
Orthology
K21054  D-erythritol 1-phosphate dehydrogenase
Genes
EFE: EFER_0337(eryB)
IZH: FEM41_12535
KLN: LH22_12785
PANT: PSNIH1_13470
PANS: FCN45_09690
SPIU: SPICUR_04395
SROS: BBH56_05250
HHU: AR456_16135
ZDF: AN401_08000
BUL: BW21_6391
MLO: mlr7270
SME: SMc01620(eryB)
SMX: SM11_chr1027(eryB)
SMI: BN406_02056(glpD1)
SMEL: SM2011_c01620(eryB)
SMER: DU99_12515
SMD: Smed_2156
RHI: NGR_b17450(eryB)
SFD: USDA257_c12950(glpD1)
EAD: OV14_3645(eryB)
ARA: Arad_7458(glpD)
RLE: pRL120205(eryB)
RLG: Rleg_5324
RGA: RGR602_PC00577(glpD-2)
SHZ: shn_16430
BME: BMEII0429
BMEL: DK63_2810
BMEE: DK62_2588
BMF: BAB2_0371
BMB: BruAb2_0367(eryB)
BABO: DK55_2361
BABR: DO74_2781
BABT: DK49_2871
BABB: DK48_2330
BABU: DK53_2371
BABS: DK51_2950
BABC: DO78_2689
BMS: BRA0865(eryB)
BSI: BS1330_II0858(eryB)
BSF: BSS2_II0820(eryB)
BSZ: DK67_2819
BSV: BSVBI22_B0857(eryB)
BOV: BOV_A0812(eryB)
BCS: BCAN_B0883(glpD)
BOL: BCOUA_II0865(eryB)
BCAR: DK60_2556
BCAS: DA85_14610
BMR: BMI_II859(eryB)
BPP: BPI_II921(eryB)
BPV: DK65_2784
OAN: Oant_2910
OAH: DR92_3595
BRA: BRADO4792(glpD)
BBT: BBta_3233(glpD)
AOL: S58_28820
BRO: BRAD285_2451(glpD)
BBAR: RHAL1_00621(glpD_1)
MMED: Mame_00677(glpD_1)
RDE: RD1_3631(glpD)
RLI: RLO149_c008350(glpD1)
OAR: OA238_c42150(glpD2)
MALG: MALG_04507
ACR: Acry_2574
AMV: ACMV_28990(glpD)
SHUM: STHU_34040
 » show all
Taxonomy
Reference
1  [PMID:163226]
  Authors
Sperry JF, Robertson DC
  Title
Erythritol catabolism by Brucella abortus.
  Journal
J Bacteriol 121:619-30 (1975)
Reference
2  [PMID:10708387]
  Authors
Sangari FJ, Aguero J, Garcia-Lobo JM
  Title
The genes for erythritol catabolism are organized as an inducible operon in Brucella abortus.
  Journal
Microbiology 146 ( Pt 2):487-95 (2000)
DOI:10.1099/00221287-146-2-487
  Sequence
[bmf:BAB2_0371]
Reference
3  [PMID:25453104]
  Authors
Barbier T, Collard F, Zuniga-Ripa A, Moriyon I, Godard T, Becker J, Wittmann C, Van Schaftingen E, Letesson JJ
  Title
Erythritol feeds the pentose phosphate pathway via three new isomerases leading to D-erythrose-4-phosphate in Brucella.
  Journal
Proc Natl Acad Sci U S A 111:17815-20 (2014)
DOI:10.1073/pnas.1414622111
  Sequence
[bmf:BAB2_0371]
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.402
IUBMB Enzyme Nomenclature: 1.1.1.402
ExPASy - ENZYME nomenclature database: 1.1.1.402
BRENDA, the Enzyme Database: 1.1.1.402

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