KEGG   ENZYME: 1.1.1.402
Entry
EC 1.1.1.402                Enzyme                                 
Name
D-erythritol 1-phosphate dehydrogenase;
eryB (gene name)
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
D-erythritol-1-phosphate 2-oxidoreductase
Reaction(IUBMB)
D-erythritol 1-phosphate + NADP+ = D-erythrulose 1-phosphate + NADPH + H+ [RN:R11341]
Reaction(KEGG)
R11341
Substrate
D-erythritol 1-phosphate [CPD:C21294];
NADP+ [CPD:C00006]
Product
D-erythrulose 1-phosphate [CPD:C21285];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
The enzyme, characterized from the pathogenic bacterium Brucella abortus, which causes brucellosis in livestock, participates in erythritol catabolism.
History
EC 1.1.1.402 created 2016
Orthology
K21054  D-erythritol 1-phosphate dehydrogenase
Genes
EFEEFER_0337(eryB)
IZHFEM41_12535
RBADH2866_13065
KLNLH22_12785
PANTPSNIH1_13470
PANSFCN45_09690
PDISD8B20_08525
PERLAC65_07495
PAGRE2H98_07000
HPEGEAO82_18800
CEBB0D95_06020
CEKD0B88_14400
CEGD0C16_06465
SPOIIMCC21906_00646
MTHDA3224_12040
MIIBTJ40_04115
CBGCbuG_1074(glpD)
CBCCbuK_0906(glpD)
TEETel_09900
SPIUSPICUR_04395
SROSBBH56_05250
HHUAR456_16135
HSVHNO53_17770
KAKKalk_20560
MPRIMP3633_1146(eryB)
MARDIBG28_06480
MFOIJSY38_15315
MPRFJ8N69_12370
ZDFAN401_08000
BHGI6G56_00375
BULBW21_6391
BUDAQ610_18855
CARIFNU76_09895
AMIMMIM_c32210(glpD)
BBAGE1O_27190
NLCEBAPG3_010020
URUDSM104443_03389(eryB)
UPLDSM104440_02897(eryB)
BEBABWI17_10065
MLOmlr7270
MLNA9174_29265
MCIMesci_5321
MOPMesop_5788
MAMMesau_05282
MAMOA6B35_10930
MESWA9K65_029085
MESMEJ066_15410
MHUAMCHK_0789
MJREB229_29845
MERDEB233_25890
MESRFGU64_19810
NKIKW403_04760(glpD)
SMESMc01620(eryB)
SMKSinme_2212
SMQSinmeB_2056
SMXSM11_chr1027(eryB)
SMIBN406_02056(glpD1)
SMEGC770_GR4Chr2290
SMELSM2011_c01620(eryB)
SMERDU99_12515
SMDSmed_2156 Smed_5463
RHINGR_b17450(eryB)
SFDUSDA257_c12950(glpD1)
SIXBSY16_3609
SINOSS05631_b56400
EADOV14_3645(eryB)
EAHFA04_11250
ARAArad_7458(glpD)
ARUIG6M88_17465
RLEpRL120205(eryB)
RLGRleg_5324
RLBRLEG3_09635
RTRRTCIAT899_PC05565
RGARGR602_PC00577(glpD-2)
RJGCCGE525_32060
RHRCKA34_19825
RGRFZ934_27775
RIIFFM53_025725
RBANJ2J98_21285
RRGJ3P73_24985
SHZshn_16430
SZOK8M09_21715
SOJK6301_18135
BMEBMEII0429
BMELDK63_2810
BMIBMEA_B0844
BMZBM28_B0831
BMGBM590_B0828
BMWBMNI_II0805
BMEEDK62_2588
BMFBAB2_0371
BMBBruAb2_0367(eryB)
BMCBAbS19_II03480
BAABAA13334_II00822
BABODK55_2361
BABRDO74_2781
BABTDK49_2871
BABBDK48_2330
BABUDK53_2371
BABSDK51_2950
BABCDO78_2689
BMSBRA0865(eryB)
BSIBS1330_II0858(eryB)
BSFBSS2_II0820(eryB)
BSUIBSSP1_II0809
BSUPBSPT1_II0806
BSUVBSPT2_II0807
BSUCBSSP2_II0818
BMTBSUIS_B0858
BSZDK67_2819
BSVBSVBI22_B0857(eryB)
BSWIY71_15320
BSGIY72_15270
BOVBOV_A0812(eryB)
BCSBCAN_B0883(glpD)
BSKBCA52141_II1824
BOLBCOUA_II0865(eryB)
BCARDK60_2556
BCASDA85_14610
BMRBMI_II859(eryB)
BPPBPI_II921(eryB)
BPVDK65_2784
BCETV910_200427
BCEEV568_200480
BVLBF3285c2_0389
BRUBFS01_12170
BRJBKD03_02245
OINIAR37_20570
BIOBR141012304_20151
OANOant_2910
OAHDR92_3595
OPSA8A54_12270
OCHCES85_5818
OCRHGK82_17645
OCLGTN27_20215
BRABRADO4792(glpD)
BBTBBta_3233(glpD)
AOLS58_28820
BROBRAD285_2451(glpD)
BRKCWS35_34685
BELBE61_33900(glpD)
BSEPHAP48_0033280
AZCAZC_2709
LNEFZC33_03430
MOCBB934_05015
MIVC4E04_13600
MICOGDR74_06715
BBARRHAL1_00621(glpD_1)
HNIW911_13440
MMEDMame_00677(glpD_1)
AUAM673_13445
AALAIGS74_12590
AALMLUX29_14480
NOHG5V57_07820 G5V57_19530(glpD)
LABTFIU93_29495(glpD3)
LAGGB0E33_29570
LIZLGH83_10260
RDERD1_3631(glpD)
RLIRLO149_c008350(glpD1)
OAROA238_c42150(glpD2)
CMARIMCC12053_405
MALGMALG_04507
TPROGa0080559_TMP2158
MALUKU6B_05460
PALXGQA70_00740
PARREOJ32_06600
PAAKFIU66_09030
PLIAE4191_09995
PMAUCP157_02322(glpD_1)
DONBSK21_15640
THWBMG03_00105
TECAKL02_018060
GFUKM031_18500
PPAFI8N54_11320
RBZB9057_14850
HDHG5B40_05630(glpD)
HBAHbal_2821
NDRHT578_10810
SNJA7E77_04040
SMYBJP26_13030
SPANAWL63_22475
SARIH5J25_05950(glpD)
SSUAFPZ54_07900
SAERNEF64_04180
SPPHKFK14_12265(glpD)
PALGHFP57_05650(glpD)
SMICSmB9_26000
CMANA9D14_08205
PNSA9D12_14120
ACRAcry_2574
AMVACMV_28990(glpD)
KBAA0U89_05185
RMTIAI58_17475(glpD)
NCHA0U93_09655
SHUMSTHU_34040 STHU_48280
SVCSTVA_08870(eryB)
STELSTAQ_43590
SKTIGS68_16125(glpD)
SMUCJL100_009990(glpD)
SROEJL101_009915(glpD)
FERFNB15_20700
HTQFRZ44_18340
HADHFRZ61_28830
THACCSC3H3_22380
ECOGFIV45_00875
MAIMICA_609
MANA11S_532
AQGHRU87_01515
 » show all
Reference
1  [PMID:163226]
  Authors
Sperry JF, Robertson DC
  Title
Erythritol catabolism by Brucella abortus.
  Journal
J Bacteriol 121:619-30 (1975)
DOI:10.1128/JB.121.2.619-630.1975
Reference
2  [PMID:10708387]
  Authors
Sangari FJ, Aguero J, Garcia-Lobo JM
  Title
The genes for erythritol catabolism are organized as an inducible operon in Brucella abortus.
  Journal
Microbiology 146 ( Pt 2):487-95 (2000)
DOI:10.1099/00221287-146-2-487
  Sequence
[bmf:BAB2_0371]
Reference
3  [PMID:25453104]
  Authors
Barbier T, Collard F, Zuniga-Ripa A, Moriyon I, Godard T, Becker J, Wittmann C, Van Schaftingen E, Letesson JJ
  Title
Erythritol feeds the pentose phosphate pathway via three new isomerases leading to D-erythrose-4-phosphate in Brucella.
  Journal
Proc Natl Acad Sci U S A 111:17815-20 (2014)
DOI:10.1073/pnas.1414622111
  Sequence
[bmf:BAB2_0371]
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.402
IUBMB Enzyme Nomenclature: 1.1.1.402
ExPASy - ENZYME nomenclature database: 1.1.1.402
BRENDA, the Enzyme Database: 1.1.1.402

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