KEGG   ENZYME: 1.1.1.407Help
Entry
EC 1.1.1.407                Enzyme                                 

Name
D-altritol 5-dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
D-altritol:NAD+ 5-oxidoreductase
Reaction(IUBMB)
D-altritol + NAD+ = D-tagatose + NADH + H+ [RN:R11638]
Reaction(KEGG)
Substrate
D-altritol [CPD:C21524];
NAD+ [CPD:C00003]
Product
D-tagatose [CPD:C00795];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
The enzyme, characterized in Agrobacterium fabrum C58, also has low activity with D-mannitol and D-arabinitol. It is part of a D-altritol degradation pathway.
History
EC 1.1.1.407 created 2017
Orthology
K21616  D-altritol 5-dehydrogenase
Genes
PHD: 102330122
MAMO: A6B35_14980
SIX: BSY16_5966
ATU: Atu3163
ATF: Ach5_30180
AGR: AGROH133_10700
ARO: B0909_22780
RET: RHE_PC00217
REL: REMIM1_PB00222
REP: IE4803_PD00663
OAN: Oant_3849
OAH: DR92_2642
PDE: Pden_4840
 » show all
Taxonomy
Reference
1  [PMID:26472925]
  Authors
Wichelecki DJ, Vetting MW, Chou L, Al-Obaidi N, Bouvier JT, Almo SC, Gerlt JA
  Title
ATP-binding Cassette (ABC) Transport System Solute-binding Protein-guided Identification of Novel d-Altritol and Galactitol Catabolic Pathways in Agrobacterium tumefaciens C58.
  Journal
J Biol Chem 290:28963-76 (2015)
DOI:10.1074/jbc.M115.686857
  Sequence
[atu:Atu3163]
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.407
IUBMB Enzyme Nomenclature: 1.1.1.407
ExPASy - ENZYME nomenclature database: 1.1.1.407
BRENDA, the Enzyme Database: 1.1.1.407

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