KEGG   ENZYME: 1.1.1.407
Entry
EC 1.1.1.407                Enzyme                                 
Name
D-altritol 5-dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
D-altritol:NAD+ 5-oxidoreductase
Reaction(IUBMB)
D-altritol + NAD+ = D-tagatose + NADH + H+ [RN:R11638]
Reaction(KEGG)
R11638
Substrate
D-altritol [CPD:C21524];
NAD+ [CPD:C00003]
Product
D-tagatose [CPD:C00795];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
The enzyme, characterized in Agrobacterium fabrum C58, also has low activity with D-mannitol and D-arabinitol. It is part of a D-altritol degradation pathway.
History
EC 1.1.1.407 created 2017
Orthology
K21616  D-altritol 5-dehydrogenase
Genes
MAMOA6B35_14980
PHYLHB779_04870
SIXBSY16_5966
ATUAtu3163
AGRAGROH133_10700
ATFAch5_30180
AROB0909_22780
ARUIG6M88_23015
RETRHE_PC00217
RELREMIM1_PB00222
REPIE4803_PD00663
REIIE4771_PE00687
RIRBN877_II0149
RHNAMJ98_PB00288
RHXAMK02_PB00303
RHKKim5_PD00636
REZAMJ99_PA00288
RHRCKA34_32590
ROYG3A56_17445
RLSHB780_13015
SOJK6301_23640
OINIAR37_17060
OANOant_3849
OAHDR92_2642
OPSA8A54_22830
OCHCES85_2927
OCRHGK82_21705
OCLGTN27_16185
PLEOOHA_1_03633(tdh)
AUAM673_21985
PDEPden_4840
PCELHUB94_15975
 » show all
Reference
1  [PMID:26472925]
  Authors
Wichelecki DJ, Vetting MW, Chou L, Al-Obaidi N, Bouvier JT, Almo SC, Gerlt JA
  Title
ATP-binding Cassette (ABC) Transport System Solute-binding Protein-guided Identification of Novel d-Altritol and Galactitol Catabolic Pathways in Agrobacterium tumefaciens C58.
  Journal
J Biol Chem 290:28963-76 (2015)
DOI:10.1074/jbc.M115.686857
  Sequence
[atu:Atu3163]
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.407
IUBMB Enzyme Nomenclature: 1.1.1.407
ExPASy - ENZYME nomenclature database: 1.1.1.407
BRENDA, the Enzyme Database: 1.1.1.407

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