KEGG   ENZYME: 1.1.1.411Help
Entry
EC 1.1.1.411                Enzyme                                 

Name
L-threonate 2-dehydrogenase;
ltnD (gene name)
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
L-threonate:NAD+ 2-oxidoreductase
Reaction(IUBMB)
L-threonate + NAD+ = 2-dehydro-L-erythronate + NADH + H+
Substrate
L-threonate [CPD:C01620];
NAD+ [CPD:C00003]
Product
2-dehydro-L-erythronate [CPD:C21618];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
The enzyme, characterized from bacteria, is involved in L-threonate catabolism.
History
EC 1.1.1.411 created 2017
Orthology
K08319  L-threonate 2-dehydrogenase
Genes
ECO: b2736(ygbJ)
ECJ: JW2706(ygbJ)
ECD: ECDH10B_2904(ygbJ)
EBW: BWG_2472(ygbJ)
ECOK: ECMDS42_2241(ygbJ)
EOJ: ECO26_3801(ygbJ)
EOI: ECO111_3456(ygbJ)
EOH: ECO103_3274(ygbJ)
ECG: E2348C_3002(ygbJ)
ESO: O3O_19775
ESM: O3M_05915
ESL: O3K_05870
ELH: ETEC_2927
ECC: c3297(ygbJ)
ECP: ECP_2714
ECI: UTI89_C3102(ygbJ)
ECV: APECO1_3788(ygbJ)
ECY: ECSE_2984
ECR: ECIAI1_2831(ygbJ)
ECQ: ECED1_3189(ygbJ)
ECK: EC55989_3003(ygbJ)
ECZ: ECS88_3003(ygbJ)
ESE: ECSF_2530
EBR: ECB_02586(ygbJ)
EBD: ECBD_0988
EKF: KO11_09315(ygbJ)
EAB: ECABU_c30090(ygbJ)
EDJ: ECDH1ME8569_2646(ygbJ)
EIH: ECOK1_3111(garR)
ELW: ECW_m2938(ygbJ)
ELL: WFL_14345(ygbJ)
ELC: i14_3026(ygbJ)
ELD: i02_3026(ygbJ)
EBL: ECD_02586(ygbJ)
EBE: B21_02551(ygbJ)
ELF: LF82_3139(ygbJ)
ECOI: ECOPMV1_02994(garR_2)
ECOJ: P423_14990
ECOS: EC958_3004(ygbJ)
STM: STM2918(ygbJ)
SEO: STM14_3520(ygbJ)
SEY: SL1344_2897(ygbJ)
SEJ: STMUK_2907(ygbJ)
SEB: STM474_3058(ygbJ)
SENI: CY43_15230
SPT: SPA2775(ygbJ)
SEK: SSPA2587
SEI: SPC_2960(ygbJ)
SEC: SCH_2848(ygbJ)
SHB: SU5_03397
SENS: Q786_14060
SED: SeD_A3227
SEG: SG2821(ygbJ)
SEL: SPUL_2916
SET: SEN2757(ygbJ)
SENA: AU38_14005
SENO: AU37_14015
SENV: AU39_14015
SENQ: AU40_15770
SENL: IY59_14610
SEEP: I137_13890
SENE: IA1_13980
SBG: SBG_2532
SBZ: A464_2935
SFV: SFV_2767
SFN: SFy_3922
SFS: SFyv_4000
SFT: NCTC1_03033(Hgd)
SSN: SSON_2884
SBO: SBO_2784
KPU: KP1_2632
KPP: A79E_2631
KPT: VK055_0893(ygbJ)
KPR: KPR_2490
KPX: PMK1_03926(hgd)
KVA: Kvar_2738
SPE: Spro_1492
SMAF: D781_1421
SMW: SMWW4_v1c14780(ygbJ)
SMAR: SM39_0934
SERF: L085_21065
ECA: ECA4327
PATR: EV46_21545
PATO: GZ59_44230
PCT: PC1_0118
PEC: W5S_0114
ETA: ETA_23680
EPY: EpC_25030
EPR: EPYR_02709(ygbJ)
EAM: EAMY_1099(ygbJ)
EAY: EAM_1106
EBI: EbC_42940
EGE: EM595_2345(ygbJ)
PAM: PANA_2459(ygbJ)
PLF: PANA5342_1627(ygbJ)
PAJ: PAJ_1756(ygbJ)
PVA: Pvag_1942(ygbJ)
PSTW: DSJ_15820
PLU: plu2507
PAY: PAU_02019(orf39)
PSI: S70_07805
PSX: DR96_1611
PRG: RB151_005660(hgd)
PHEI: NCTC12003_00569(Hgd)
ETR: ETAE_1922
ETD: ETAF_1734
LRI: NCTC12151_03006(garR_2)
HIN: HI1010
HIU: HIB_11490
HIZ: R2866_1375(ygbJ)
HIA: H733_1430
HAP: HAPS_1865
HPAS: JL26_10370
HPAK: JT17_07620
HSO: HS_0012
HSM: HSM_1903
PMU: PM1366
PMP: Pmu_15970
PMUL: DR93_199
MSU: MS1981(mmsB)
MHT: D648_1690
MHAT: B824_24920
MHAE: F382_07300
MHAM: J450_07730
MHAL: N220_00785
MHAQ: WC39_13280
MHAY: VK67_13285
MVR: X781_1120
ASU: Asuc_0123
AAT: D11S_0028
AAN: D7S_01614
AACN: AANUM_1071
VAG: N646_4715
PMK: MDS_1712
PSB: Psyr_0466
PSYR: N018_02240
PFL: PFL_3346
PPRC: PFLCHA0_c33770(ygbJ)
PPRO: PPC_3370
PFS: PFLU_2352
PSES: PSCI_2111
PSEM: TO66_13335
PSOS: POS17_2720
PTN: PTRA_a2901(ygbJ)
FBL: Fbal_1240
GAI: IMCC3135_12985(hgd_2)
CSA: Csal_3178
HAM: HALO0631
AHA: AHA_1061
AMED: B224_4225
ACAV: VI35_16030
CHJ: NCTC10426_00305(garR)
PSE: NH8B_1338(mmsB)
RPI: Rpic_3732
REH: H16_A1562(h16_A1562)
RME: Rmet_1835(ygbJ)
CGD: CR3_2188
BMA: BMAA0577(garR)
BML: BMA10229_0890(garR)
BMN: BMA10247_A1857(garR)
BMAI: DM57_12635
BMAF: DM51_4298
BMAZ: BM44_4835
BMAB: BM45_4898
BPS: BPSS1415
BPL: BURPS1106A_A1920(garR)
BPSE: BDL_4722
BPSM: BBQ_4733
BPSU: BBN_4860
BPSD: BBX_3885
BPK: BBK_4024
BPSH: DR55_3860
BPSA: BBU_4623
BPSO: X996_3648
BUT: X994_5703
BTQ: BTQ_4272
BTJ: BTJ_5310
BTZ: BTL_3772
BTD: BTI_3907
BTV: BTHA_4111
BTHE: BTN_3886
BTHM: BTRA_3769
BTHA: DR62_3928
BTHL: BG87_3728
BOK: DM82_5571
BOC: BG90_5039
BCN: Bcen_3212
BCJ: BCAM2395
BCEN: DM39_5452
BCEW: DM40_3059
BCEO: I35_6291
BAM: Bamb_4550
BMU: Bmul_3500
BMJ: BMULJ_05017(mmsB)
BMK: DM80_4891
BMUL: NP80_5035
BCT: GEM_3298
BCED: DM42_5593
BDL: AK34_3423
BCON: NL30_00465
BUB: BW23_3607
BLAT: WK25_27870
BTEI: WS51_08940
BSEM: WJ12_31910
BPSL: WS57_02150
BMEC: WJ16_30435
BSTG: WT74_30820
BGU: KS03_5426
BGO: BM43_4280
BUL: BW21_5901
BGP: BGL_2c05840(bdhA2)
BXE: Bxe_B2172
BXB: DR64_4502
BPH: Bphy_4423
BFN: OI25_6549
PNU: Pnuc_1634
PLG: NCTC10937_05030(Hgd_2)
BPAR: BN117_3757
BBR: BB1031
AXX: ERS451415_05696(Hgd_2)
RFR: Rfer_0446
POL: Bpro_4883
VEI: Veis_3388
DAC: Daci_2811
LIM: L103DPR2_00241(hgd_1) L103DPR2_01663(hgd_2)
LIH: L63ED372_02491(hgd_2) L63ED372_02639(hgd_3)
CFU: CFU_3492
CARE: LT85_4010
RGE: RGE_14690(ygbJ)
SMD: Smed_4321
ARA: Arad_9439
RLG: Rleg_5012
BME: BMEII1090
BMEL: DK63_2168
BMEE: DK62_2108
BABR: DO74_2302
BSZ: DK67_2173
BOV: BOV_A0134
BCAR: DK60_3028
BMR: BMI_II147
BPP: BPI_II147
BPV: DK65_2320
BJA: blr2928
BRA: BRADO2551
BBT: BBta_2897
BRS: S23_50870
AOL: S58_50620
BRAD: BF49_1763
RPD: RPD_1854
VGO: GJW-30_1_03462(Hgd_3)
AZC: AZC_2777
MAQU: Maq22A_c12795(mmsB) Maq22A_c16685(mmsB)
BID: Bind_2085
HDI: HDIA_1243(Hgd_2) HDIA_3161(garR_4)
RBM: TEF_13710
SIL: SPO2560(garR)
RDE: RD1_3786(mmsB)
DSH: Dshi_4221
MALG: MALG_01533
RHC: RGUI_4076
SPSE: SULPSESMR1_01365(hgd)
RMM: ROSMUCSMR3_03165(garR)
ACR: Acry_2431
LPIL: LIP_3223
MID: MIP_00171
MMM: W7S_08120
MSHG: MSG_00289
SMAL: SMALA_0040
RBA: RB13140(mmsB)
 » show all
Taxonomy
Reference
1  [PMID:27402745]
  Authors
Zhang X, Carter MS, Vetting MW, San Francisco B, Zhao S, Al-Obaidi NF, Solbiati JO, Thiaville JJ, de Crecy-Lagard V, Jacobson MP, Almo SC, Gerlt JA
  Title
Assignment of function to a domain of unknown function: DUF1537 is a new kinase family in catabolic pathways for acid sugars.
  Journal
Proc Natl Acad Sci U S A 113:E4161-9 (2016)
DOI:10.1073/pnas.1605546113
  Sequence
[reh:H16_A1562]
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.411
IUBMB Enzyme Nomenclature: 1.1.1.411
ExPASy - ENZYME nomenclature database: 1.1.1.411
BRENDA, the Enzyme Database: 1.1.1.411

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