KEGG   ENZYME: 1.1.1.420
Entry
EC 1.1.1.420                Enzyme                                 
Name
D-apiose dehydrogenase;
apsD (gene name)
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
D-apiofuranose:NAD+ 1-oxidoreductase
Reaction(IUBMB)
D-apiofuranose + NAD+ = D-apionolactone + NADH + H+ [RN:R12502]
Reaction(KEGG)
R12502
Substrate
D-apiofuranose [CPD:C21040];
NAD+ [CPD:C00003]
Product
D-apionolactone [CPD:C22218];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
The enzyme, characterized from several bacterial species, is involved in a catabolic pathway for D-apiose.
History
EC 1.1.1.420 created 2019
Orthology
K23244  D-apiose dehydrogenase
Genes
YELLC20_03977
YAKACZ76_03285
YMADA391_06270
YHID5F51_15710
COLWA3Q33_17725
CATEC2869_05170
GAIIMCC3135_02045(yhhX_1) IMCC3135_20395(yhhX_2) IMCC3135_21765(yhhX_3)
HAAA5892_08245
KMAB9H00_09335
BCAIK788_0005386
PSPWBJG93_30030
PTERC2L65_18735
PGPCUJ91_23805
PTSCUJ90_28675
PACPFAZ97_28280
PEWKZJ38_24870
CARIFNU76_22540
AKATKWG_00535
AMIMMIM_c01400
RHYRD110_19505
POLBpro_3819
VAPVapar_6269
VAAAX767_13030
HYLLPB072_16415 LPB072_19470
HYCE5678_14695
BEBABWI17_02130
MLOmll7010
MLNA9174_13150
MCIMesci_5311
MOPMesop_5772
MAMMesau_05267
MAMOA6B35_09525 A6B35_15265
MESWA9K65_029035
MESMEJ066_15520
MHUAMCHK_0234
MJREB229_13285
MERDEB233_28460
MESOBSQ44_08090
PHTBLM14_21715
NIYFQ775_04630
NKIKW403_09355
ORMHTY61_08760 HTY61_11910
SMESM_b20353
SMKSinme_3825
SMQSinmeB_4321
SMXSM11_pD1260
SMIBN406_06319
SMEGC770_GR4pD1249
SMELSM2011_b20353
SMERDU99_31530
SMDSmed_3766
RHINGR_b22030
SFHSFHH103_05028
SFDUSDA257_c23090
SIXBSY16_3623
SAMESAMCFNEI73_pC0431
SINOSS05631_b62710
EADOV14_b0209
ARAArad_9238
RETRHE_PF00033
RECRHECIAT_PC0000973
RELREMIM1_PF00037
RLERL4420 pRL120389
RLTRleg2_4658
RLGRleg_3954 Rleg_4755
RLBRLEG3_07460 RLEG3_30850
RTRRTCIAT899_PC04810
RHLLPU83_pLPU83c0530
RGARGR602_PC01948
RHNAMJ98_PE00036
RPHAAMC79_PD00980
RHXAMK02_PD00039
REZAMJ99_PD00036
RJGCCGE525_32375
RHRCKA34_20650
RGRFZ934_27690
RADCO657_28340
RIIFFM53_014910 FFM53_024655
RBANJ2J98_22070
RRGJ3P73_22875 J3P73_25320
RLSHB780_06745
RFVRFYW14_03811
SHZshn_27380
SZOK8M09_21790
SOJK6301_18790
KAIK32_08100 K32_40750
OINIAR37_15410
OANOant_3060
OAHDR92_3443
OPSA8A54_12325
OCHCES85_5830
OCRHGK82_18425
OCLGTN27_19440
BOPAXW83_04865 AXW83_12440
BVVBHK69_03780
XDIEZH22_15220
STARG3545_23065
LNEFZC33_05825
METM446_1313
MMESMMSR116_11450
MTADM6G65_24040
MOCBB934_35085 BB934_40840
CHELAL346_05100
DEIC4375_04970
MMEDMame_04748(afr_4)
AUAM673_08895
AALAIGS74_19120
AALMLUX29_21310
AUZSa4125_32750
RBMTEF_16860
LAPACP90_20155
LABRCHH27_00105
LABPFJ695_09720
LABTFIU93_26710(ydgJ) FIU93_28805(afr4)
LAGGB0E33_03880 B0E33_28845
LIZLGH83_09595
ACUTMRB58_05620 MRB58_21515
RUAD1823_13410
RUTFIU92_00100(afr1)
JANJann_3062
RDERD1_3788
RLIRLO149_c006530
RPONG3256_03960
DSHDshi_3394
OAROA238_c24210
CMARIMCC12053_385
MALGMALG_04066
YPACCEW88_19410
TPROGa0080559_TMP299
SULZC1J03_17545
SULIC1J05_01780
SMEDJNX03_08285
TOMBWR18_11220
AHTANTHELSMS3_02504(ligC) ANTHELSMS3_04965(iolX)
THAACFI11_01770
OCDFHY55_04930 FHY55_15985
MALUKU6B_32170
HATRC74_03020 RC74_11925 RC74_11940
PALXGQA70_00805 GQA70_20180
LSALKBK07_12645
PARREOJ32_13825
PLIAE4191_17645
PMAUCP157_00839(iolG_2)
DAAAKL17_3256
TECAKL02_017820
GEHHYN69_13940
LITFPZ52_12595
POZI0K15_15440
PALWPSAL_036690(apsD_2)
PPAFI8N54_14200
CACTHZ995_04510
HDHG5B40_16325
FAPGR316_12720
FAQG5B39_17465
AMAQGO499_13005 GO499_14460
GOYGLS_c05880
ACRAcry_1061
AMVACMV_08300
LCKHN018_21640
SHUMSTHU_22600
SVCSTVA_26220
SKTIGS68_04965
SMUCJL100_022755
SROEJL101_021440
FERFNB15_20160
HADHFRZ61_46810
SNEANBZ79_06410
BOUI5818_05095
PJDPjdr2_3665
PPYPPE_03804
PAEQR50912_07855
PRIPRIO_3529
PSWUSY83_22150
PPSCEHS13_08910
PALBEJC50_26040
PRZGZH47_24970 GZH47_30105
PLYCGXP70_14455 GXP70_21880 GXP70_27330
PTRIKDC22_07460
PALOE6C60_0877 E6C60_1021
CCHLFPL14_15860
AFXJZ786_10315
PLANA1s21148_06255
TROtrd_0133
TTRTter_1997
RBARB3770
MFFMFFC18_42680(idhA)
AHELQ31a_38410(kynB)
RLCK227x_46470(iolG_15)
PNDPla175_51100(kynB)
MRIMal4_38880(ycjS_5)
SACISinac_4983
AGVOJF2_37170(ycjS_3)
ABASACPOL_4621
PMUCING2E5A_0782
HHYHalhy_1306
SMONAWR27_07845
RHOZGXP67_17710
RSIRunsl_3639
FBTD770_14515
FSNGS03_01704(iolG_1)
MAREEJ994_10370
ZGAZOBELLIA_3794
FEKC1H87_18525
AQDD1816_12935
ASAGFGM00_05285
HRRHZS55_13205
 » show all
Reference
1  [PMID:29867142]
  Authors
Carter MS, Zhang X, Huang H, Bouvier JT, Francisco BS, Vetting MW, Al-Obaidi N, Bonanno JB, Ghosh A, Zallot RG, Andersen HM, Almo SC, Gerlt JA
  Title
Functional assignment of multiple catabolic pathways for D-apiose.
  Journal
Nat Chem Biol 14:696-705 (2018)
DOI:10.1038/s41589-018-0067-7
  Sequence
[ara:Arad_9238]
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.420
IUBMB Enzyme Nomenclature: 1.1.1.420
ExPASy - ENZYME nomenclature database: 1.1.1.420
BRENDA, the Enzyme Database: 1.1.1.420

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