KEGG   ENZYME: 1.1.1.425
Entry
EC 1.1.1.425                Enzyme                                 
Name
levoglucosan dehydrogenase;
1,6-anhydro-beta-D-glucose dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
1,6-anhydro-beta-D-glucopyranose:NAD+ 3-oxidoreductase
Reaction(IUBMB)
levoglucosan + NAD+ = 3-dehydrolevoglucosan + NADH + H+ [RN:R12713]
Reaction(KEGG)
R12713
Substrate
levoglucosan [CPD:C22350];
NAD+ [CPD:C00003]
Product
3-dehydrolevoglucosan [CPD:C22351];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
Levoglucosan is formed from the pyrolysis of carbohydrates such as starch and cellulose and is an important molecular marker for pollution from biomass burning. This enzyme is present only in bacteria, and has been characterized from Arthrobacter sp. I-552 and Pseudarthrobacter phenanthrenivorans. cf. EC 2.7.1.232, levoglucosan kinase.
History
EC 1.1.1.425 created 2021
Orthology
K24995  levoglucosan dehydrogenase
Genes
PEZHWQ56_09195
PALVKSS97_18160
RFOREIFOR_02758(iolG)
SMIBN406_06768
RHINGR_b19940
SFDUSDA257_c18000 USDA257_c18100
SAMESAMCFNEI73_pC1598
RELREMIM1_PF00849 REMIM1_PF00875
REPIE4803_CH03661 IE4803_CH03684
RLTRleg2_4779
RGRFZ934_12315
PHLKKY_2595 KKY_3864
PEMOF122_01755
DEIC4375_04075
DSALK1X15_12760
PZHCX676_22085
PTPRCA23_c12140
LVSLOKVESSMR4R_02604(iolX)
FAQG5B39_17710
BACQDOE78_19795
BCOBcell_0373 Bcell_0375
BMQBMQ_1775
BMDBMD_3622
BMEGBG04_545
BFXBC359_10195
BKWBkAM31D_16255(gfo_2)
FECQNH15_23435
ACOPRI196_17985
SALEEPH95_12700
NTMBTDUT50_05740
MEKUHUW50_14340
MLITKDJ21_026285
DOMRRU94_18690 RRU94_18985
SHVAAT16_11375 AAT16_11385
PPYPPE_00856
POWIJ21_32400 IJ21_33360
PAUNMJA45_12980
COHEAV92_02890
AFASNZD89_04425
JEOJMA_08640 JMA_08660
EAVEH197_20100
BCOCBLCOC_12790(iolG_7) BLCOC_12850(iolG_8)
LUAD4A81_10270
WHJH9Q79_00380 H9Q79_00410
CMIUB1H56_01165
TEXTeth514_0988
THXThet_1927
MLVCVS47_02172(afr_3)
MSFIT882_02490
RLARhola_00001010
ARTArth_1911
ARTHC3B78_05130
ARTYAHiyo4_11790
PUEFV140_21400
PNVJMY29_03820
APNAsphe3_10730
PDELJCQ34_05035
POKSMD14_05310 SMD14_05515
KFVAS188_10240
MLYCJ228_009200
SATKSA2016_1510
TEZBKM78_07725
TLATLA_TLA_01561(iolX_2)
NHYJQS43_03090
DGODGo_PB0088
DAHDAETH_26080
 » show all
Reference
1  [PMID:7765713]
  Authors
Nakahara K, Kitamura Y, Yamagishi Y, Shoun H, Yasui T.
  Title
Levoglucosan dehydrogenase involved in the assimilation of levoglucosan in Arthrobacter sp. I-552.
  Journal
Biosci Biotechnol Biochem 58:2193-6 (1994)
DOI:10.1271/bbb.58.2193
Reference
2  [PMID:30224354]
  Authors
Sugiura M, Nakahara M, Yamada C, Arakawa T, Kitaoka M, Fushinobu S.
  Title
Identification, functional characterization, and crystal structure determination of bacterial levoglucosan dehydrogenase.
  Journal
J Biol Chem 293:17375-17386 (2018)
DOI:10.1074/jbc.RA118.004963
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.425
IUBMB Enzyme Nomenclature: 1.1.1.425
ExPASy - ENZYME nomenclature database: 1.1.1.425
BRENDA, the Enzyme Database: 1.1.1.425

DBGET integrated database retrieval system