Entry |
|
Name |
L-gulonate 3-dehydrogenase;
L-3-aldonate dehydrogenase;
L-3-aldonic dehydrogenase;
L-gulonic acid dehydrogenase;
L-beta-hydroxyacid dehydrogenase;
L-beta-hydroxy-acid-NAD+-oxidoreductase;
L-3-hydroxyacid dehydrogenase
|
Class |
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
|
Sysname |
L-gulonate:NAD+ 3-oxidoreductase
|
Reaction(IUBMB) |
L-gulonate + NAD+ = 3-dehydro-L-gulonate + NADH + H+ [RN: R02640]
|
Reaction(KEGG) |
|
Substrate |
|
Product |
|
Comment |
Also oxidizes other L-3-hydroxyacids.
|
History |
EC 1.1.1.45 created 1961
|
Pathway |
ec00040 | Pentose and glucuronate interconversions |
|
Orthology |
K13247 | L-gulonate 3-dehydrogenase |
|
Genes |
» show all
|
Reference |
1 |
Authors |
Dworsky, P. and Hoffmann-Ostenhof, O. |
Title |
L-3-Aldonic acid dehydrogenase from Schwanniomyces occidentalis. |
Journal |
Acta Biochim Pol 11:269-277 (1964) |
Reference |
2 |
Authors |
Smiley, J.D. and Ashwell, G. |
Title |
Purification and properties of beta-L-hydroxy acid dehydrogenase. II. Isolation of beta-keto-L-gluconic acid, an intermediate in L-xylulose biosynthesis. |
Journal |
J Biol Chem 236:357-364 (1961) |
Other DBs |
ExplorEnz - The Enzyme Database: | 1.1.1.45 |
ExPASy - ENZYME nomenclature database: | 1.1.1.45 |
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