KEGG ENZYME: 1.1.1.53

ENZYME: 1.1.1.53

Entry

EC 1.1.1.53                 Enzyme

Name

3alpha(or 20beta)-hydroxysteroid dehydrogenase;
cortisone reductase;
(R)-20-hydroxysteroid dehydrogenase;
20beta-hydroxy steroid dehydrogenase;
Delta4-3-ketosteroid hydrogenase;
20beta-hydroxysteroid dehydrogenase;
3alpha,20beta-hydroxysteroid:NAD+-oxidoreductase;
NADH-20beta-hydroxysteroid dehydrogenase;
20beta-HSD

Class

Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor

Sysname

3alpha(or 20beta)-hydroxysteroid:NAD+ oxidoreductase

Reaction(IUBMB)

androstan-3alpha,17beta-diol + NAD+ = 17beta-hydroxyandrostan-3-one + NADH + H+ [RN:R04330]

Reaction(KEGG)

R04330;
(other) R04831 R04834 R04844 R04847

Substrate

androstan-3alpha,17beta-diol [CPD:C03852];
NAD+ [CPD:C00003]

Product

17beta-hydroxyandrostan-3-one [CPD:C03917];
NADH [CPD:C00004];
H+ [CPD:C00080]

Comment

The 3alpha-hydroxy group or 20beta-hydroxy group of pregnane and androstane steroids can act as donor.

History

EC 1.1.1.53 created 1961, modified 1986

Pathway

ec00140

Steroid hormone biosynthesis

ec01100

Metabolic pathways

Orthology

K00038

3alpha(or 20beta)-hydroxysteroid dehydrogenase

Genes

XEU:	XSP_000405

LUS:	E5843_13750

TBV:	H9L17_09835

THEX:

ICG51_001210

LAEG:

L2Y94_07840

LAEO:

L2Y97_07255

VNA:	PN96_21715

PRE:	PCA10_29440

PMED:

E3Z27_09510 E3Z27_11200

PSET:

THL1_4166

PPSH:

G5J76_09175

PLAL:

FXN65_05805

PMAO:

PMYSY11_2429(fabG)

PRW:	PsycPRwf_0909

PSPG:

AK823_06640

PSYG:

AK825_06710

PSYY:

DLE54_04590

PCIA:

Q6344_06310

PRAE:

MN210_06160

ATN:	FM020_06230

COLW:

A3Q33_18725

PHA:

PSHAa0891

PTN:	PTRA_a1023

PNG:	PNIG_a1074

SNAN:

I6N98_03900 I6N98_08295 I6N98_16655

STAW:

NCG89_00400

ZAL:	AZF00_09860

HJA:	BST95_16185

HALC:

EY643_05850

AFUS:

EYZ66_11750

PAQM:

E0F26_01700

HAA:	A5892_06475

TWAN:

HUF19_05280

SDF:	ACG33_09105

SOK:	D0B54_05230

FCE:	JN531_005490 JN531_015650

RIN:	ACS15_4336(fabG3) ACS15_4362

BUR:	Bcep18194_B1012 Bcep18194_B1510

BCJ:	BCAM1582 BCAM1939

BCEN:

DM39_3414 DM39_5921(fabG3)

BCEO:

I35_5441 I35_5764

BAC:	BamMC406_4338 BamMC406_4593

BCT:	GEM_3731 GEM_4145

BCED:

DM42_6063 DM42_6378

BCEP:

APZ15_29245 APZ15_31375

BPYR:

ABD05_26060 ABD05_28010

BCON:

NL30_02625 NL30_04350

BDF:	WI26_21000 WI26_22930

BTEI:

WS51_05555

BPSL:

WS57_04565 WS57_06195

BMEC:

WJ16_26575 WJ16_28160

BSTL:

BBJ41_21130 BBJ41_23190

BANN:

JFN94_25465 JFN94_27665

BARI:

NLX30_27770 NLX30_30390

BAEN:

L3V59_21525 L3V59_23920

BURK:

DM992_32785 DM992_41105

PPAI:

E1956_08285 E1956_17110 E1956_31290 E1956_37475

TVL:	FAZ95_14925

BPC:

BPTD_2805

BPER:

BN118_3087

BPET:

B1917_0998

BPEU:

Q425_25250

BBM:	BN115_1129

BHO:

D560_0970

BHM:

D558_0953

BHZ:	ACR54_03739

BTRM:

SAMEA390648701966

BBRO:

BAU06_10380 BAU06_13355

BPDZ:

BBN53_04245

AXY:	AXYL_03129

AIS:	BUW96_05625

ACHR:

C2U31_27620

APES:

FOC84_18800 FOC84_29860

AAEG:

RA224_17390

ODI:

ODI_R3001

ODH:	DHf2319_03925

AAA:

Acav_2984

VBO:	CKY39_24380

VAM:	C4F17_10110

CRJ:	QMY55_06980

HPSE:

HPF_00465(fabG2)

HYN:	F9K07_07760

DIH:	G7047_28880

MPT:

Mpe_A0883

METP:

C1M51_13615

GLC:	JQN73_12650

DOE:	DENOEST_0155 DENOEST_2223(fabG) DENOEST_3326(fabG)

EBA:

ebA309

AZA:

AZKH_2309

THU:	AC731_008520

THAU:

C4PIVTH_4241(fabG)

TCL:

Tchl_1579

TAK:	Tharo_2923

MESP:

C1M53_08770

MESR:

FGU64_09845

MESO:

BSQ44_24850

AAK:	AA2016_6632

PECT:

BN1012_Phect2465

RJG:	CCGE525_03295

KAI:	K32_24590(fabG3)

BJA:	bll0026(bll0026)

BJU:	BJ6T_00290

BJP:	RN69_00125

BIC:	LMTR13_26415

BOT:	CIT37_14680

BEL:	BE61_00280 BE61_20990

BDG:	LPJ38_07075

BSEP:

HAP48_0005085 HAP48_0026745

BQB:	J4P68_0025100

BBAN:

J4G43_014970 J4G43_042965

BPAH:

QA639_34940

TALZ:

RPMA_26175

METI:

DK427_23595

MMED:

Mame_00673(fabG3)

CAUL:

KCG34_11370

BND:	KWG56_07595

BALB:

M8231_11780

CEH:	CEW89_04480

MALG:

MALG_00957

YPAC:

CEW88_22185 CEW88_23330

TPRO:

Ga0080559_TMP4125

PLCG:

RVY76_01925

PSEW:

JHW44_17050

PALS:

PAF20_18180

SALO:

EF888_11210

PALW:

PSAL_021450(fabG3)

CMAG:

CBW24_16305

NAR:	Saro_0512 Saro_3460 Saro_3667

NPP:	PP1Y_AT12924 PP1Y_AT13611 PP1Y_Mpl3491

NRE:	BES08_01630 BES08_04100 BES08_30480

NOV:	TQ38_027450

NOT:	C7W88_18590 C7W88_20490

NGF:	FRF71_08450

NOG:	GKE62_06620 GKE62_15160

NCP:	U0041_06355 U0041_06375

SPHK:

SKP52_13035(linX1)

SMAG:

AN936_15185

SMAZ:

LH19_03100

SGI:	SGRAN_1043(fabG3.1) SGRAN_3272(ucpA) SGRAN_3288(fabG3)

SPFD:

SPYCA_3265 SPYCA_3651

SWI:	Swit_0925 Swit_3288

SPHD:

HY78_03490 HY78_09115 HY78_21925

RDI:	CMV14_18875

SPHM:

G432_09540 G432_18195 G432_19875 G432_20550

SSAN:

NX02_06305 NX02_07890

SPKC:

KC8_00535 KC8_14445

SPHA:

D3Y57_15355

SARI:

H5J25_02275

SBIN:

SBA_ch1_21790 SBA_ch1_21850 SBA_ch2_3740 SBA_ch2_3860(fabG3)

SABI:

PBT88_01675

SJP:	SJA_C1-18570(orfup) SJA_C2-03690 SJA_C2-05080

SINB:

SIDU_10905 SIDU_11345 SIDU_11405

SCH:	Sphch_3068 Sphch_3070 Sphch_3469 Sphch_3499 Sphch_3501

SYB:	TZ53_08530

SBD:	ATN00_07880 ATN00_18860

SPMI:

K663_15970 K663_16040 K663_17441 K663_17556 K663_17651 K663_17736 K663_19773 K663_20588 K663_22183

SPHB:

EP837_03342 EP837_03402

SPHT:

K426_23069 K426_28100 K426_28495 K426_29265

SHYD:

CJD35_06240 CJD35_06315

SCLO:

SCLO_1032300

SUFL:

FIL70_19475

SBAR:

H5V43_09850 H5V43_21135

SPPH:

KFK14_04650 KFK14_04700 KFK14_10960

SPAG:

sphantq_01533(fabG3)

CIJ:	WG74_12050

SPHG:

AZE99_15090

SFLA:

SPHFLASMR4Y_02490(benD)

SPHY:

CHN51_06210

BLAS:

BSY18_2740

BFW:	B5J99_04655

SPHJ:

BSL82_04525 BSL82_04850

PALG:

HFP57_10445 HFP57_10490

PARJ:

J4G78_10345

PHAO:

HF685_05245 HF685_11370

SAND:

H3309_11125

POQ:	KZX46_10735

ALH:	G6N82_09335 G6N82_10755

ARUE:

QQX03_02540

QPS:	K3166_01545

ELQ:	Ga0102493_111082 Ga0102493_11146

ERF:	FIU90_01720(fabG2)

PNS:	A9D12_03615

ERYT:

KDC96_13685

PORL:

BG023_11303

PHZ:	CHX26_01280

POT:	E2E27_02170

PORC:

CBR61_00880

NTD:	EGO55_02230 EGO55_02235 EGO55_04030 EGO55_05565 EGO55_14475 EGO55_15345

CAEN:

K5X80_06045 K5X80_06050 K5X80_12515

THAR:

T8K17_15080

GME:	Gmet_2226 Gmet_2249

CFUS:

CYFUS_004796

BKO:	CKF48_08115

CSOA:

LIS82_01415

OIH:	OB0329 OB3314

OCN:	CUC15_03415 CUC15_10040 CUC15_19410

OCB:	CV093_03510 CV093_20940

OJD:	NP439_02985 NP439_05875

OON:	NP440_05910

AXL:	AXY_03970 AXY_05670

LGY:	T479_23465

LYZ:	DCE79_09825

LYG:	C1N55_20120

LYC:	FH508_0017485 FH508_0023605

LLB:	R6U77_05400

HHD:	HBHAL_1912

HLI:

HLI_05210

HNZ:	P9989_02655

HSHI:

MUO14_06860

VNE:	CFK40_02885

VIM:	GWK91_10805 GWK91_10845

VNT:	OLD84_17240

VIK:	KFZ58_18755 KFZ58_18780

SJE:	AAV35_000655

PASA:

BAOM_2736

PPSR:

I6J18_05930

RAX:	KO561_04730

BTHV:

CQJ30_05665

PSYH:

D0S48_12500 D0S48_18415

PSYO:

PB01_20610

PSYB:

KD050_14105

PRD:	F7984_06510 F7984_12640

GCS:	MUN88_10080

GSM:	MUN87_08675 MUN87_19915

RUE:	DT065_05935

SALE:

EPH95_17095

SCIA:

HUG15_20780

NMK:	CHR53_06320

NNV:	QNH39_14495

SEDD:

ERJ70_17995

BOU:	I5818_25625

PHJ:	LC071_17575

AHAL:

FTX54_001415

SEQO:

SE1039_01100

SSIF:

AL483_10050

SNL:	BJD96_13540

SFQ:	C7J90_03390

SPSD:

JMB28_00455 JMB28_13165

STAP:

AOB58_1705

SGAI:

K3U27_11165

MLEN:

H3V22_11510

MBOE:

HT586_00345

NAMP:

KPF49_00150

NMY:	CJ229_006370

EAP:	KB235_00795

EAUR:

NMQ00_14780

PNP:	IJ22_27100

PPAB:

KET34_17660

CHEB:

HH215_21285

PLIG:

NAG76_08770

ADAU:

NZD86_01700

AFAS:

NZD89_06645

SIV:	SSIL_1656 SSIL_1982

SSIL:

SOLI23_08825 SOLI23_09255 SOLI23_13810

SOB:	CSE16_13975

PLN:	Plano_2785 Plano_2867

PKU:	AUO94_01820

PLL:	I858_009050

PDG:	BCM40_00895

PHC:	BBI08_11145 BBI08_11450

PMAR:

B0X71_03575

PPLA:

BBI15_10875

PFAE:

AJGP001_15800

PLX:	CW734_17225

PGQ:	FK545_05410

PLAY:

DNR44_008330 DNR44_016720

PLIQ:

QWY22_17635

PSHE:

QWY16_17970 QWY16_17975

PSHX:

QWY21_04055

KUR:	ASO14_1945

KZO:	NCTC404_01768(fabG3)

SPSY:

AZE41_00865

LRE:

Lreu_1659

LRF:

LAR_1548

LRT:

LRI_0330

LRR:	N134_09120

LFN:	LF145_04490 LF145_07640

LPOR:

PRK60_05335

LBH:

Lbuc_0640

LBN:	LBUCD034_0661

LPAR:

FAM21731_00303

LCU:	PL11_001170 PL11_003070

LKF:	DNL43_02165 DNL43_04100

LHIL:

G8J22_00873(cpnA_3)

LBR:

LVIS_0166

LBK:	LVISKB_0165

LKO:	ABN16_07495

LSUA:

H3M12_05300

LNA:	RIN67_00620

LHO:	LOOC260_102960

LOL:	LACOL_1341

LNN:	F0161_08745

LPD:	AYR62_00725 AYR62_14590

LMAE:

FGL90_03765 FGL90_03980

LGE:	C269_05050

WJO:	FOL01_0085

ESS:	ATZ33_02920

ERAF:

J9537_17035

VFV:	K5K99_10625

VLC:	G314FT_06400(cpnA)

AUH:	AWM75_00685 AWM75_07335

FCT:	NRE15_03980

FHM:	R0V13_02445

JDA:	BW727_101599(fabG3)

JAR:	G7057_07460

JPO:	G7058_07520

EUZ:	DVS28_a0297

MTU:	Rv2002(fabG3)

MTV:

RVBD_2002

MTC:

MT2058

MRA:	MRA_2018(fabG3-1)

MTF:	TBFG_12034

MTB:	TBMG_01984

MTK:	TBSG_01995

MTZ:	TBXG_001968

MTG:	MRGA327_12335

MTI:	MRGA423_12455

MTE:	CCDC5079_1849

MTUR:

CFBS_2112(fabG4)

MTL:	CCDC5180_1824

MTO:	MTCTRI2_2036(fabG3)

MTD:	UDA_2002(fabG3)

MTN:	ERDMAN_2205(fabG3)

MTJ:	J112_10705

MTUB:

MT7199_2033

MTUC:

J113_13820

MTUE:

J114_10710

MTX:	M943_10400

MTUH:

I917_14135

MTUL:

TBHG_01960

MTUT:

HKBT1_2108(fabG3)

MTUU:

HKBT2_2108(fabG3)

MTQ:	HKBS1_2113(fabG3)

MBO:	BQ2027_MB2025(fabG3)

MBB:	BCG_2019(fabG3)

MBT:	JTY_2014(fabG3)

MBM:	BCGMEX_2001(fabG3)

MBK:	K60_020750

MBX:

BCGT_1815

MAF:	MAF_20140(fabG3)

MMIC:

RN08_2216

MCE:	MCAN_20221(fabG3)

MCQ:	BN44_40286(fabG)

MCV:	BN43_31181(fabG)

MCX:	BN42_30300(fabG)

MCZ:	BN45_50280(fabG)

MORY:

MO_002098

MPA:	MAP_1739c(fabG3) MAP_3577(fabG3)

MAO:	MAP4_0196 MAP4_2091

MAVI:

RC58_00925 RC58_10425

MAVU:

RE97_00930 RE97_10435

MAV:	MAV_2509 MAV_5136

MIT:	OCO_25040 OCO_49440 OCO_49620

MIA:	OCU_24910 OCU_49370 OCU_49550

MID:	MIP_03466 MIP_07512

MYO:	OEM_23470 OEM_49790

MCHI:

AN480_10595 AN480_12590 AN480_25755

MIR:	OCQ_23590 OCQ_50430 OCQ_50610

MMAL:

CKJ54_11350 CKJ54_23645

MLP:

MLM_0339

MMAN:

MMAN_13910(fabG3) MMAN_22090 MMAN_37530 MMAN_37720

MSER:

MTY59_12820 MTY59_13030 MTY59_35630 MTY59_40730(fabG3)

MSA:	Mycsm_03420

MUL:	MUL_1037(fabG3) MUL_1052

MMI:	MMAR_0387(fabG3) MMAR_0402 MMAR_2981(fabG3_1)

MMAE:

MMARE11_03500(fabG3) MMARE11_03650 MMARE11_29030(fabG3_1)

MLI:	MULP_00374(fabG3) MULP_00390 MULP_02842(hsd)

MPSE:

MPSD_04850 MPSD_05020 MPSD_30880(fabG3)

MSHO:

MSHO_14370 MSHO_17770 MSHO_44670(fabG3)

MMC:	Mmcs_2023 Mmcs_2711

MKM:	Mkms_2069 Mkms_2755

MJL:	Mjls_2006 Mjls_2741

MMM:	W7S_12085 W7S_24845

MKN:	MKAN_00800 MKAN_28930

MYV:	G155_12070 G155_12915 G155_12965 G155_16070

MYE:	AB431_05070 AB431_16440 AB431_22900

MDX:	BTO20_12655 BTO20_16230 BTO20_21805 BTO20_21855 BTO20_22770 BTO20_33665

MSHG:

MSG_00321 MSG_00342 MSG_02794(fabG3)

MFJ:	MFLOJ_03720(fabG3) MFLOJ_31740 MFLOJ_31960

MSTO:

MSTO_04900(fabG3) MSTO_30990 MSTO_35760 MSTO_35960

MSIM:

MSIM_21370 MSIM_21550 MSIM_48280(fabG3)

MSAK:

MSAS_09560 MSAS_36950

MKU:	I2456_02150 I2456_12855 I2456_13760

MLW:	MJO58_01755 MJO58_01850 MJO58_15170

MXE:	MYXE_24870

MNV:	MNVI_41600

MPAG:

C0J29_02140 C0J29_02220 C0J29_15030 C0J29_26240

MNM:	MNVM_16720 MNVM_17100 MNVM_24720

MGOR:

H0P51_02085 H0P51_02170 H0P51_14260 H0P51_24465 H0P51_27850

MCOO:

MCOO_09790 MCOO_13180(fabG3) MCOO_26090 MCOO_33200 MCOO_34830

MBAI:

MB901379_00298(fabG3_1) MB901379_02410(fabG3_2)

MSEO:

MSEO_16750(fabG3) MSEO_42120 MSEO_42380

MHEK:

JMUB5695_02395

MGAU:

MGALJ_07160 MGALJ_15880

MLJ:	MLAC_40580

MBRD:

MBRA_13470 MBRA_13800 MBRA_21160 MBRA_21270 MBRA_38710 MBRA_56620

MSHJ:

MSHI_33140

MMAM:

K3U93_01530 K3U93_01630 K3U93_13515

MSPG:

F6B93_12640

MOT:	LTS72_10280 LTS72_11205

MPAA:

MKK62_09880 MKK62_12615 MKK62_17850 MKK62_23390

MMEH:

M5I08_16260

MKY:	IWGMT90018_03900 IWGMT90018_04070 IWGMT90018_29330 IWGMT90018_31180(fabG3) IWGMT90018_45800 IWGMT90018_51980 IWGMT90018_54800

MADI:

A7U43_15625 A7U43_19645

MWU:	PT015_06075 PT015_07645 PT015_15040 PT015_19120 PT015_24380

MYW:	BVC93_14320

MSM:	MSMEG_2566 MSMEG_3515

MSG:	MSMEI_2506 MSMEI_3435(fabG3)

MSB:	LJ00_12770 LJ00_17490

MSN:	LI99_12770 LI99_17495

MSH:	LI98_12775 LI98_17500

MVA:	Mvan_2242 Mvan_3000

MGI:	Mflv_3281 Mflv_4104 Mflv_4505

MSP:	Mspyr1_26090 Mspyr1_34470 Mspyr1_39040

MCB:	Mycch_1986 Mycch_2878

MNE:	D174_15310

MYN:	MyAD_15035

MFT:	XA26_24780 XA26_26560 XA26_26650 XA26_32940

MPHL:

MPHLCCUG_02190 MPHLCCUG_02464(fabG3_1)

MVQ:	MYVA_1698(fabG3_1) MYVA_2160 MYVA_3063

MLL:	B1R94_04800 B1R94_13320

MRH:	MycrhN_4957

MTHN:

4412656_01659(cpnA_1)

MHAS:

MHAS_01896(fabG3) MHAS_02516(budC_1)

MDU:	MDUV_12030 MDUV_22710 MDUV_26530(fabG3)

MCHT:

MCHIJ_10070 MCHIJ_48900 MCHIJ_50700

MDR:	MDOR_20150

MAUU:

NCTC10437_01629(fabG3_2) NCTC10437_01670(fabG3_3) NCTC10437_02095(cpnA_2) NCTC10437_02864(fabG3_4)

MMAG:

MMAD_29420

MMOR:

MMOR_01060(fabG3) MMOR_34190 MMOR_41880

MFX:	MFAL_09760(fabG3) MFAL_26240

MAIC:

MAIC_28470 MAIC_41240 MAIC_46760

MIJ:	MINS_06760 MINS_06980 MINS_17180 MINS_26630(fabG3)

MALV:

MALV_14380

MTY:	MTOK_12840

MPSC:

MPSYJ_35150 MPSYJ_47960(fabG3)

MARZ:

MARA_08730 MARA_18070 MARA_41710

MGAD:

MGAD_08890 MGAD_16900

MHEV:

MHEL_07890 MHEL_12810 MHEL_52170 MHEL_52640(fabG3)

MSAR:

MSAR_24440 MSAR_39920

MANY:

MANY_14220 MANY_48780

MAUB:

MAUB_06520 MAUB_32270

MPOF:

MPOR_21830(fabG3) MPOR_25700 MPOR_34590

MPHU:

MPHO_06080 MPHO_37900 MPHO_44050

MMUC:

C1S78_011420 C1S78_015290 C1S78_025265 C1S78_028900

MMAT:

MMAGJ_55570 MMAGJ_57490 MMAGJ_57590 MMAGJ_65450

MBOK:

MBOE_41540 MBOE_48220 MBOE_48320 MBOE_50060

MFG:	K6L26_15835 K6L26_19260 K6L26_19310 K6L26_20155

MSEI:

MSEDJ_43000

MFLV:

NCTC10271_02453(fabG3_2) NCTC10271_03265(fabG3_3)

MCEE:

MCEL_07180 MCEL_14920

MMON:

EWR22_10275 EWR22_14410

MGO:	AFA91_08275 AFA91_22235

MHOL:

K3U96_12295 K3U96_16495 K3U96_25150

MSEN:

K3U95_13530 K3U95_16840 K3U95_16890 K3U95_17735

MPAE:

K0O64_04640 K0O64_15535 K0O64_22495

MRF:	MJO55_08275 MJO55_14575

MDF:	K0O62_11610 K0O62_15075 K0O62_15395

MCRO:

MI149_05305 MI149_16495 MI149_22920

MGRO:

FZ046_20440

MAUS:

JN090_10235 JN090_14285

MKR:	MKOR_29100

MPAK:

MIU77_08305 MIU77_10320 MIU77_17920

MAB:

MAB_4680c

MMV:	MYCMA_2579

MABB:

MASS_4710

MABL:

MMASJCM_4737

MCHE:

BB28_23275

MIZ:	BAB75_26335

MSTE:

MSTE_04731 MSTE_04845

MJD:	JDM601_0114(fabG) JDM601_0150(fabG3) JDM601_3608(fabG3)

MTER:

4434518_00102(fabG_2) 4434518_00137(fabG3_2) 4434518_03587(fabG3_5)

MMIN:

MMIN_11380 MMIN_18930

MHIB:

MHIB_30100 MHIB_33520 MHIB_33870

MHER:

K3U94_00725 K3U94_00910 K3U94_20380 K3U94_20435 K3U94_20470

MVM:	MJO54_00590 MJO54_00775 MJO54_20295 MJO54_20355 MJO54_20395

ASD:	AS9A_1016 AS9A_3858(fabG3)

CGT:

cgR_2841

CGS:	C624_14475

CGG:	C629_14480

CCJZ:

ccrud_00420

CPRE:

Csp1_00440

CSUR:

N24_0097

CCOY:

CCOY_03055(cpnA)

NFA:	NFA_22600 NFA_33550 NFA_48060

NFR:	ERS450000_00698(fabG3)

NCY:	NOCYR_1615(fabG) NOCYR_2461 NOCYR_2947

NBR:	O3I_010095 O3I_018235

NNO:	NONO_c26260(fabG5) NONO_c48960 NONO_c58990(fabG2) NONO_c59020(fabG3)

NSL:	BOX37_08620 BOX37_14000

NSR:	NS506_04686(entA) NS506_05856 NS506_06833 NS506_06835 NS506_06837

NTP:	CRH09_27185

NOZ:	DMB37_01165 DMB37_30710 DMB37_39935

NOD:	FOH10_15135 FOH10_22775 FOH10_22785

NAH:	F5544_13290

NAD:	NCTC11293_02699(fabG3) NCTC11293_03775

NWL:	NWFMUON74_28980 NWFMUON74_38050 NWFMUON74_45400(fabG3)

NIE:	KV110_10550

NTC:	KHQ06_23635 KHQ06_30460 KHQ06_35335 KHQ06_36020

NHU:	H0264_24860 H0264_34510 H0264_34520 H0264_34530

NYA:	LTV02_38470 LTV02_38480 LTV02_38490

NGP:	LTT66_03735 LTT66_28655 LTT66_28665 LTT66_28675 LTT66_31165 LTT66_32100

NSPU:

IFM12276_28420 IFM12276_28440(fabG3) IFM12276_28460 IFM12276_31090 IFM12276_47120

NYU:	D7D52_09695 D7D52_09705 D7D52_09715 D7D52_22935

RHA:	RHA1_ro01882 RHA1_ro05413

RER:	RER_11770 RER_34300 RER_49510 RER_51600

REY:	O5Y_05380 O5Y_23485 O5Y_24400

REB:	XU06_05625 XU06_23900 XU06_24820

RQI:	C1M55_05830 C1M55_25055 C1M55_26020

ROP:	ROP_06510 ROP_15600 ROP_20270 ROP_27350

ROA:	Pd630_LPD05001 Pd630_LPD06047 Pd630_LPD06502 Pd630_LPD07460 Pd630_LPD09005

RPY:	Y013_13845

RHB:	NY08_2135 NY08_3965

RHW:	BFN03_18320

RRZ:	CS378_16940

RHOD:

AOT96_04810 AOT96_05830 AOT96_16260 AOT96_31780 AOT96_32015

RRT:	4535765_04493(cpnA)

RCR:	NCTC10994_02926

RTM:	G4H71_08550

RKO:	JWS14_09625 JWS14_18420

RGO:	KYT97_13180 KYT97_14585

ROZ:	CBI38_01400 CBI38_08610 CBI38_08685 CBI38_14800

RPSK:

JWS13_33800 JWS13_36210

RGOR:

NMQ04_19245

RHOO:

RA302_05775 RA302_16300 RA302_24095

RHOJ:

JVH1_27880 JVH1_38765 JVH1_39960 JVH1_41835

RHS:	A3Q41_02365(cpnA)

REQ:	REQ_30210 REQ_44360 REQ_45140

WHR:	OG579_05625

GBR:

Gbro_2728

GPO:	GPOL_174p01110

GOR:	KTR9_0248 KTR9_2607 KTR9_4418

GTA:	BCM27_06705 BCM27_13840 BCM27_17645

GOM:	D7316_01206(fabG3) D7316_02578 D7316_02846

GOS:	QAD21_13635

GOJ:	GR168_13085

GAM:	GII34_12835

GPD:	GII33_12100

GJI:	H1R19_13115

GOI:	LK459_12875 LK459_20650

GHN:	MVF96_13585

GAMI:

IHQ52_13825 IHQ52_14405

GMG:	NWF22_12110

SPIN:

KV203_10865

TPR:

Tpau_3804

TSM:	ASU32_21655 ASU32_23550

TPUL:

TPB0596_41400

TSD:	MTP03_42830

DIZ:	CT688_15730

DPC:	A6048_16505

TOY:	FO059_01530

SCO:	SCO4169(SCD66.06)

SALB:

XNR_5139

SMA:	SAVERM_3801

SGR:	SGR_4223 SGR_48t SGR_7091t

SGB:

WQO_14335

SFI:

SFUL_2902

SANL:

KZO11_14795

SGRF:

SGFS_001730 SGFS_030920 SGFS_053880 SGFS_086400

SCYE:

R2B67_20950

SCB:	SCAB_52021 SCAB_90611

SSX:	SACTE_6250

SVL:	Strvi_1003 Strvi_3325 Strvi_7622

SHY:

SHJG_8575

SHO:	SHJGH_8335

SRC:	M271_08610 M271_12330 M271_20795 M271_44275 M271_44440

SMAL:

SMALA_4577

SSOI:

I1A49_26945

SBH:	SBI_06326 SBI_09851

SVE:	SVEN_1285 SVEN_1674 SVEN_3092

SDV:	BN159_0879 BN159_5018

STRP:

F750_7032

SCI:	B446_16900

SLV:	SLIV_17530

SVT:	SVTN_07885 SVTN_16140 SVTN_35935 SVTN_35940

STRE:

GZL_01228 GZL_05178 GZL_06850

SCW:	TU94_25175

SLD:	T261_0450 T261_4799

SLC:	SL103_02785

STRM:

M444_10315 M444_15505

STRC:

AA958_21590 AA958_24355

SAMB:

SAM23877_1099

SPRI:

SPRI_4289

SCZ:	ABE83_21445

SCX:	AS200_01815 AS200_04425 AS200_26065

SRW:	TUE45_04311

SLE:	sle_17540(sle_17540)

SPAV:

Spa2297_15340

STRT:

A8713_30375

SCLF:

BB341_11290

SGS:	AVL59_44245

STSI:

A4E84_03035 A4E84_17350

SKY:	D0C37_00540 D0C37_27685

SALW:

CP975_15050

SGM:	GCM10017557_35720

SCAD:

DN051_22305 DN051_43555

SPHW:

NFX46_19065 NFX46_23270 NFX46_37215

SLS:	SLINC_3715

SNR:	SNOUR_05180 SNOUR_23770 SNOUR_31920

SALU:

DC74_2167 DC74_3711 DC74_7418

SALL:

SAZ_11415 SAZ_19725 SAZ_38295

SPLU:

LK06_018905

STRD:

NI25_04545 NI25_21240

SAUO:

BV401_26735

SSIA:

A7J05_20295

SVU:	B1H20_13700

SPUN:

BFF78_24030

SGV:	B1H19_17970

SLAU:

SLA_3144

SALF:

SMD44_03674

SALJ:

SMD11_3946

SLX:	SLAV_16565 SLAV_25060 SLAV_27205

STRO:

STRMOE7_17040

SFK:	KY5_1543 KY5_1993 KY5_3511c

SNZ:	DC008_14825

SGE:	DWG14_04802

SRJ:

SRO_4203

SLK:	SLUN_17075

SDX:	C4B68_22895

SGD:	ELQ87_22165

SQZ:	FQU76_13180

SCYA:

EJ357_06005 EJ357_19805 EJ357_36955

SNQ:	CP978_31940

STIR:

DDW44_13050

SKA:	CP970_24780 CP970_32610 CP970_34985

SVN:	CP980_19440 CP980_22770 CP980_24785

SNK:	CP967_29825

SHAW:

CEB94_06210 CEB94_17810

SRK:	FGW37_13685

SFIC:

EIZ62_18960

SGAL:

CP966_15695

SSPO:

DDQ41_12955

SFY:	GFH48_23205

SAQU:

EJC51_07950 EJC51_08360 EJC51_22135

SGF:	HEP81_04375

SCAV:

CVT27_13165

SRIM:

CP984_32835

SSUB:

CP968_19290 CP968_22630 CP968_24605

SPHV:

F9278_10100 F9278_20515

SCIN:

CP977_07410

STSU:

B7R87_12760

SCHA:

CP983_24305

SGX:	H4W23_08345 H4W23_17425 H4W23_38565

SCOE:

CP976_19270

SSPB:

CP982_19245

SNF:	JYK04_02686 JYK04_03137 JYK04_03864

SPLA:

CP981_16765

SBRO:

GQF42_20320

STUI:

GCM10017668_29960

SATA:

C5746_09050 C5746_18045

SHUN:

DWB77_04418

SCYG:

S1361_17560

SFEU:

IM697_04510

SDW:	K7C20_16040

SCAL:

I6J39_13960

SAUH:

SU9_014265

SPEU:

CGZ69_15405

SROI:

IAG44_23480

SXN:	IAG42_02280 IAG42_20070 IAG42_20335 IAG42_26585 IAG42_31490

SGJ:	IAG43_18090

SHK:	J2N69_15480

SANU:

K7396_20765

STRY:

EQG64_13920

SACT:

DMT42_03415

SMAO:

CAG99_13885

SGOB:

test1122_09840

SINE:

KI385_05795 KI385_10680 KI385_19835

SLF:	JEQ17_01220 JEQ17_01875 JEQ17_20370

SDEC:

L3078_00465 L3078_19780

SAOV:

G3H79_21060

SDUR:

M4V62_24250 M4V62_31040 M4V62_33385 M4V62_39820

SYAN:

NRK68_09085 NRK68_11205 NRK68_14560

SRUG:

F0345_01090 F0345_04520

SAKB:

K1J60_00345 K1J60_25020 K1J60_42615

STAA:

LDH80_23075 LDH80_31065 LDH80_36430 LDH80_36435

SNIG:

HEK616_00470 HEK616_31530 HEK616_31570

SVIO:

HWN34_00390 HWN34_25955

SCAE:

IHE65_00395 IHE65_25555

STUB:

MMF93_11175 MMF93_14270 MMF93_22545

SSPN:

LXH13_23340

SCIR:

STRCI_003632

SXT:	KPP03845_102248 KPP03845_102643 KPP03845_103382

SLON:

LGI35_14000 LGI35_20470 LGI35_20805

STUD:

STRTU_004103

SENG:

OJ254_11805

SGK:	PET44_08935 PET44_14260

SANT:

QR300_18325

SYUN:

MOV08_04975 MOV08_24205 MOV08_31955

SJN:	RI060_24250 RI060_36855

SCYN:

N8I84_18230 N8I84_40220

SOV:	QZH56_20755

SFIY:

F0344_20925 F0344_33435

SHAU:

K9S39_25640

SKG:	KJK29_21580 KJK29_33620

SCOA:

QU709_24135

SLAI:

P8A22_22620 P8A22_31300

SROC:

RGF97_27615

SFP:	QUY26_22695

STTN:

BSL84_14310

SINN:

ABB07_21555

KBU:	Q4V64_04110 Q4V64_22590 Q4V64_43410

SARM:

DVA86_28695

SPRF:

K4G22_00035

SLUO:

PS467_24655

STPB:

QR97_14990

SRPA:

HEP86_17650

SMIB:

SMIR_21305 SMIR_35980 SMIR_36380 SMIR_39610

SCAJ:

O1G22_10645 O1G22_23880 O1G22_44090

STRW:

QHG49_20075

STRL:

HEP84_05460 HEP84_08810 HEP84_23530

STSD:

HEP87_08540 HEP87_24475

SRPZ:

HEP85_18070

KSK:

KSE_72210

KAB:	B7C62_13655

KIS:	HUT16_34180

STRI:

C7M71_025015

YIA:	LO772_01105

STRH:

GXP74_35700

ABRY:

NYE86_01125

AGLA:

OIE69_23135

LXL:	KDY119_03415

MTS:

MTES_1749

MIO:	AOA12_02820

MIH:	BJP65_09795

MICR:

BMW26_01385

MHOS:

CXR34_15850

MLV:	CVS47_03327(fabG3)

MCAW:

F6J84_13990 F6J84_14585

MRN:	K8F61_02075 K8F61_03240 K8F61_07450 K8F61_08345 K8F61_15910

MBIN:

LXM64_06175

MTEC:

OAU46_11925

MRG:	SM116_16645

MICE:

EHF32_06665

MSUF:

KV394_02715

RFS:	C1I64_07390

FSB:	GCM10025867_16000

AGY:	ATC03_10780 ATC03_16405

AARC:

G127AT_07325

AMAV:

GCM10025877_10840(fabG3_1) GCM10025877_12750 GCM10025877_20120(fabG3_2)

ALAV:

MTO99_11680

AIL:	FLP10_11505

CART:

PA27867_0918 PA27867_2445

CRY:	B7495_12160

CPHY:

B5808_20160

MALK:

MalAC0309_0008

MYL:	C3E77_06050

MSPO:

KXZ72_09360

SALA:

ESZ53_03420

HUM:	DVJ78_12150

HUW:	FPZ11_17545

GRY:	D7I44_01160

LARI:

KI794_10735

FRN:	F1C15_06910 F1C15_15640

GLN:	F1C58_09550 F1C58_11465

SUBA:

LQ955_05305 LQ955_05315

GMN:	GMOLON4_2284(hsd)

ARR:	ARUE_c18690(fabG2)

ARM:

ART_3462

ARL:	AFL94_13305

ARY:	ATC04_04660

ARU:	ASPU41_04875

ARQ:	BWQ92_06470

ARN:	CGK93_10125 CGK93_10210 CGK93_11865

ARX:	ARZXY2_2070

ARTH:

C3B78_08890 C3B78_08895

ARTP:

E5206_03925

ASUN:

KG104_08275 KG104_08940 KG104_17435

ASUF:

MNQ99_09500

ACAO:

NF551_14835

AZH:	MUK71_15645

AGEG:

MUG94_07810

AOD:	Q8Z05_06680

AKO:	N9A08_14615

AZX:	N2K95_15185

AJR:	N2K98_16190

ARTU:

E7Y32_06095

ARTZ:

FCN77_12020 FCN77_14820

ARI:	UM93_09645

PAYJ:

HMI59_12275

ARZ:	AUT26_09460

ACH:

Achl_1690

APN:	Asphe3_01900

PSLS:

KTR40_04850

GPR:	JQN66_13280

KFV:	AS188_03480

KRS:	EQG70_17555

CMUA:

P8192_00420

PAEY:

KUF55_17840

LMOI:

VV02_25060

IDO:	I598_0831(fabG3)

CET:	B8281_02615

CFI:	Celf_2643 Celf_3009

CGA:	Celgi_0772

CELZ:

E5225_03245

CELH:

GXP71_02745

CELC:

K5O09_09730

CWAN:

KG103_18410

CFEN:

KG102_12940 KG102_15975

CWN:	NP075_18775

CCHE:

NP064_05000

CXIE:

NP048_18765

OEK:	FFI11_002515 FFI11_005090

JME:	EEW87_016040

TEH:	GKE56_07440

PHW:	G7075_05715

SERW:

FY030_00205

HALT:

IM660_14560

MPH:

MLP_24360

NCA:

Noca_2813

NDK:	I601_0636(fabG3_2) I601_3497(fabG3_3)

NOO:	FE634_09480 FE634_20825

NBE:	Back2_27010

NANO:

G5V58_09560 G5V58_21995

NARO:

CFH99_11625 CFH99_24150

NPI:	G7071_16050

NPC:	KUV85_04150 KUV85_04155

NMAR:

HPC71_09220

NFC:	KG111_10135

NBI:	SHK19_12595 SHK19_12800

PSIM:

KR76_12265 KR76_13560 KR76_20075 KR76_23000 KR76_25085 KR76_26980

AEZ:	C3E78_15175

AEB:	C6I20_03580

AWN:	NQV15_08780

KFL:	Kfla_1988 Kfla_2054

KQI:	F1D05_19155

KRI:	OX958_12260

THAO:

NI17_017645

TALX:

FOF52_05280

NDA:	Ndas_4479 Ndas_4656

NAL:	B005_0300(fabG3)

NAKE:

KGD83_01865 KGD83_02690

NCG:	KGD84_13590

SNAH:

OUQ99_07505

SAIU:

J4H86_22335 J4H86_22895

TCU:

Tcur_3357

ACTW:

F7P10_03555 F7P10_03595 F7P10_03625 F7P10_05405 F7P10_23435 F7P10_34755

AMAZ:

LUW76_06735 LUW76_20495 LUW76_39840

ACIR:

OG979_06380 OG979_28715

SPIQ:

OHA34_33605 OHA34_37635

ACTQ:

OG417_17385 OG417_39915 OG417_40215 OG417_40295

SRO:

Sros_1990

NOA:	BKM31_27550 BKM31_34675

NCX:	Nocox_09515(fabG7) Nocox_15940

NGN:	LCN96_10730 LCN96_19010

NFS:	OIE67_27595 OIE67_36305 OIE67_53140

FRI:	FraEuI1c_2671 FraEuI1c_3129

NML:

Namu_4881

BSD:	BLASA_2506

AMD:	AMED_2425 AMED_3705

AMN:	RAM_12335 RAM_18865

AMM:	AMES_2398 AMES_3662

AMZ:	B737_2399 B737_3662

AOI:

AORI_2393

AJA:	AJAP_22395 AJAP_26860

AMQ:	AMETH_4959

AMYC:

CU254_09925 CU254_23490 CU254_25055

AMYB:

BKN51_04580 BKN51_15900

AAB:	A4R43_01475 A4R43_07370 A4R43_16645

AMYY:

YIM_13820(fabG7) YIM_21255(fabG14) YIM_29620 YIM_36910(fabG32)

AORI:

SD37_13025

AACD:

LWP59_27350 LWP59_29840

APRT:

MUY14_24340

AROO:

NQK81_10370

ATHM:

L1857_27565 L1857_33665

ARHD:

VSH64_01260

AMOG:

QRX60_25850

ACYN:

ORV05_06615

ACOR:

LCL61_32500

PDX:

Psed_3898

PSEE:

FRP1_11655 FRP1_17245

PSEH:

XF36_15915

PSEQ:

AD006_19315 AD006_24700

PECQ:

AD017_04290 AD017_27155

PHH:	AFB00_02475 AFB00_24400

PAUT:

Pdca_02650(fabG3_1) Pdca_08390 Pdca_56640

PBRO:

HOP40_07015 HOP40_15885 HOP40_26235 HOP40_33695

PSDS:

K1T35_06425

APRE:

CNX65_24895

AMI:

Amir_5048

SACX:

IOD16_17960

KAL:

KALB_3419

KUT:	JJ691_41040

KPHY:

AOZ06_42455

LED:	BBK82_29710 BBK82_33725 BBK82_37540 BBK82_38700

AHM:	TL08_03560 TL08_24265

AHG:	AHOG_04120(fabG3)

ALO:

CRK59559

PMAD:

BAY61_15985 BAY61_17870 BAY61_20745 BAY61_23405

SACE:

GIY23_13220

ACTU:

Actkin_04294(fabG3)

ACTY:

OG774_11845

STP:	Strop_2631

SAQ:

Sare_2828

MAU:	Micau_5142

MIL:

ML5_3168

MICB:

MicB006_4161

MTUA:

CSH63_31690

MCAB:

HXZ27_31050

VMA:	VAB18032_16785

VER:	HUT12_15715 HUT12_19755

MCHL:

PVK74_15985

MPRN:

Q3V37_15320 Q3V37_30135

MICF:

QQG74_20895

AMS:	AMIS_21770 AMIS_27340 AMIS_58450

AIH:	Aiant_18330(fabG3)

ACTR:

Asp14428_48560

ACTL:

L3i22_023550 L3i22_083970(fabG3)

ASIC:

Q0Z83_038130 Q0Z83_064950

AOU:	ACTOB_004197

ACTE:

ACTI_41680 ACTI_83090(fabG_9)

PLK:	CIK06_11160

PSUU:

Psuf_093040

PRY:	Prubr_52280

DFU:	Dfulv_34430 Dfulv_34470 Dfulv_35205

NHY:	JQS43_09650

CAI:

Caci_8769

GLY:	K3N28_09060

BAST:

BAST_0247

BCOR:

BCOR_0200

BII:	BINDI_0136

BACT:

AB656_06565

SIJ:

SCIP_1264

EKE:	EK0264_09160

JCY:	M6B22_21310

AYM:	YM304_13460

ATQ:	GH723_04550

AQZ:	KSP35_14200

IAM:	HC251_11330 HC251_17800

IMA:	PO878_16405 PO878_16545

DHI:	LH044_18945

LEPV:

J4558_05300 J4558_11115

FLN:

FLA_0730

SHT:	KO02_11345

SPDR:

G6053_15640

BBD:	Belba_1029

LBY:

Lbys_0205

SEON:

BWZ22_03950

LUY:	QZH61_12205

CPIP:

CJF12_08505

CGLE:

NCTC11432_01508(fabG3)

EVA:	EIB75_12330

MBN:

Mboo_0405

» show all

Reference

1 [PMID:718844]

Authors

Edwards CA, Orr JC.

Title

Comparison of the 3alpha-and 20beta-hydroxysteroid dehydrogenase activities of the cortisone reductase of Streptomyces hydrogenans.

Journal

Biochemistry 17:4370-6 (1978)
DOI:10.1021/bi00614a003

Reference

2 [PMID:14403761]

Authors

HUEBENER HJ, SAHRHOLZ FG

Title

[20 beta-Hydroxysteroid dehydrogenase. 2. Preparation and crystallization.]

Journal

Biochem Z 333:95-105 (1960)

Reference

3 [PMID:14403760]

Authors

HUEBENER HJ, SAHRHOLZ FG, SCHMIDT-THOME J, NESEMANN G, JUNK R

Title

[20 beta-Hydroxysteroid dehydrogenase, a new crystalline enzyme.]

Journal

Biochim Biophys Acta 35:270-2 (1959)
DOI:10.1016/0006-3002(59)90366-x

Reference

4 [PMID:13549484]

Authors

LYNN WS Jr, BROWN RH.

Title

The conversion of progesterone to androgens by testes.

Journal

J Biol Chem 232:1015-30 (1958)

Reference

5 [PMID:6936053]

Authors

Strickler RC, Covey DF, Tobias B.

Title

Study of 3 alpha, 20 beta-hydroxysteroid dehydrogenase with an enzyme-generated affinity alkylator: dual enzyme activity at a single active site.

Journal

Biochemistry 19:4950-4 (1980)
DOI:10.1021/bi00563a002

Reference

6 [PMID:6928375]

Authors

Sweet F, Samant BR

Title

Bifunctional enzyme activity at the same active site: study of 3 alpha and 20 beta activity by affinity alkylation of 3 alpha, 20 beta-hydroxysteroid dehydrogenase with 17-(bromoacetoxy)steroids.

Journal

Biochemistry 19:978-86 (1980)
DOI:10.1021/bi00546a023

Other DBs

ExplorEnz - The Enzyme Database:

1.1.1.53

IUBMB Enzyme Nomenclature:

1.1.1.53

ExPASy - ENZYME nomenclature database:

1.1.1.53

BRENDA, the Enzyme Database:

1.1.1.53

CAS:

9028-42-6

DBGET integrated database retrieval system