KEGG   ENZYME: 1.1.1.80
Entry
EC 1.1.1.80                 Enzyme                                 
Name
isopropanol dehydrogenase (NADP+);
isopropanol dehydrogenase (NADP+)
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
propan-2-ol:NADP+ oxidoreductase
Reaction(IUBMB)
propan-2-ol + NADP+ = acetone + NADPH + H+ [RN:R01550]
Reaction(KEGG)
R01550
Substrate
propan-2-ol [CPD:C01845];
NADP+ [CPD:C00006]
Product
acetone [CPD:C00207];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
Also acts on other short-chain secondary alcohols and, slowly, on primary alcohols.
History
EC 1.1.1.80 created 1972
Pathway
ec00650  Butanoate metabolism
ec01100  Metabolic pathways
Orthology
K23259  isopropanol dehydrogenase (NADP+)
Genes
MGLMGL_3563
EHIEHI_023110(81.t00034)
EDIEDI_033780 EDI_125570 EDI_247390 EDI_322720
EIVEIN_184550
TVATVAG_2v0231540 TVAG_2v0470960 TVAG_2v0592710
SMACSMDB11_1707(adh)
SMWSMWW4_v1c24330(ybdR)
SMAFD781_1673
SERSSERRSCBI_11475
SRZAXX16_3425
SSURATE40_008875
PSKYA6B44_02175
PATLKGI96_02165
XFHXFHB_06515
LUMCNR27_03850
PURAOC03_05590
MMAIsS8_2497
NWANwat_2663
SDFACG33_02345
TEQTEQUI_0896
TEAKUI_0298(adh)
TEGKUK_0981(adh)
TASTASI_0286
TATKUM_1324(adh)
BPSIIX83_03610
BOZDBV39_00355
OURCEQ07_06930
ACIDCBP33_05985
ACIPCBP36_06420
ACINCBP34_05770
ACISCBP35_12525
CKEB5M06_12130
CAQTKAQ61_13370
ADNAlide_1125
ADKAlide2_3762
HYRBSY239_746
HYNF9K07_06530
DPYBA022_09960
DIADtpsy_0967
AZRCJ010_03055
HFEHFELIS_04520
HHMBN341_2080
HADCDV25_07355
HSHNHP194022_03430(adh)
CAVICAV_1667
ABUAbu_1042
ABTABED_0990
ABLA7H1H_1038
AVPAVENP_1797
ADZADFLV_1732
ARCABLL_1678
AANAAANAER_1370
DSDGD606_07855
DSXGD604_05885
DOAAXF15_06605
DEOCAY53_02390
MRMA7982_07275
PCAYFRD00_25040
GOTAXE85_05885
GMONCTC11323_00742(adh)
GEQCG018_07820
GSAFOC50_07595
PDHB9T62_07995
LFELAF_0972 LAF_1372
LFRLC40_0631 LC40_0864
LFFLBFF_1063 LBFF_1491
LORAYI71_12045 AYI71_14075
LGASLG045_00385
LPASKZE55_03290
CBKCLL_A1797(adh)
CBBCLD_1638(adh)
CBFCLI_2960(adh)
CBMCBF_2952
CLJCLJU_c24860
CPASClopa_1771
CAHCAETHG_0553
CSQCSCA_1104
CTYKCTK_C28120(adhI)
CTAEBGI42_07605
CARGRSJ17_06360
CDRKB9W14_13250
CIABEN51_01390
CDYF3K33_14815
CCOHSAMEA4530647_1599(adh)
CFERD4Z93_10405
CLOSDMR38_12850
CRWCROST_028370(adh_1)
CLOHMPREF0868_1158(aDH)
CTHDCDO33_06050
EHAEthha_2217
OVAOBV_12380(adh)
BHUbhn_I0300
BPROPMF13cell1_01309(adh_2)
BLIQINP51_14750
CSHClosa_0574
HSDSD1D_1259(adh)
LUAD4A81_01075
ACELacsn021_01250(adh)
RGNRGna_15335
CASPNQ535_24685
QDOH9Q78_07930 H9Q78_12360
SALQSYNTR_2028
CALKHUE98_15725
SGYSgly_3313
DCADesca_0375 Desca_2553
DRUDesru_2988
MDVC5Q96_00455
TTETTE0695(Tdh)
TEXTeth514_0653
THXThet_2272
TPDTeth39_0218
TITThit_2177
TMTTmath_2094
TBOThebr_0224
TWIThewi_1976 Thewi_2518
TKITKV_c22260(adh)
NCDACONDI_01845(adh)
HALSD7D81_08595
IFNGM661_06035
AVGI6H45_07990
AOBI6H46_01945
KPARJL105_10205
PFTJBW_00677
STEDSPTER_41430(adh)
AFNAcfer_0888
AINAcin_0250(adh)
MGBVO56_01055
MPULBLA55_01525
MPNMPN_564(adh)
MPMMPNA5640 MPNA5641
GPOGPOL_c02640(adh1)
SHYSHJG_2468
SHOSHJGH_2233
SPRISPRI_0214 SPRI_7139
SNWBBN63_32685
SRJSRO_0536
SGFHEP81_00518
SFEUIM697_08165
LDNH9L06_06615
ORZFNH13_03230
PPCHMPREF9154_2301
NMLNamu_3460
GOBGobs_1833
PDXPsed_1708
PAUTPdca_23080
PBROHOP40_24955
ACTTDDD63_10810
ACQAM609_01035
FVGI6G91_05680
APVApar_1228
OLSOlsu_0295
OLOADJ70_00940
TIOINP52_07520
LCALATTO_05480(adh)
CGOCorgl_1434
ABAOBEQ56_01815
MEAPMTHMO_0045(adh)
RMLFF011L_29060(adh_1)
AHELQ31a_19410(adh)
RLCK227x_05250(adh)
PLSVT03_19815(adh_1)
PLHVT85_10195(adh)
LRSPX52LOC_03707
FTJFTUN_2505
KSTKSMBR1_0080(adh_1)
ALUSSTSP2_02738(adh)
TPEDTPE_0836(mtnN)
TPKJO40_03945
TRMJO41_00510
TPHGFUT81_04210
TRIDYE50_08525
TPAVHRQ91_02290
TMEDDWB79_11170
TSKHRI97_09700
SSMSpirs_1190
SCCSpico_1615
BHYBHWA1_01862(tdh)
BHDBHYOB78_06815
BRMBmur_1378
BPOBP951000_1321(adh)
BPJB2904_orf102(tdh)
BPIPBPP43_08500
BPWWESB_0114(tdh)
BIPBint_0150(tdh)
LBALebu_1419
LEOAMK43_01010
LHFJCM16775_0994
LWDJCM16777_1389
LGOJCM16774_1651
ACOAmico_1354
TLITlie_0160
SBRSY1_03930
PPIOCE91St28_08250
PDNHMPREF9137_0305(aDH)
PFUSADJ77_06970
PMUFJ4864_05835
MSTMsp_0967(adh)
METBAW729_06385
MRUmru_0065(adh1) mru_1445(adh3)
MEYETL18_05405 TL18_05580 TL18_09010
MOLYLM1_0947
MAROMarbSA_04680 MarbSA_15090
METVK4897_04415
MEWMSWAN_0857
MCUBMCBB_0894(adh)
METNBK008_07235
MEMEHYG87_06875
TGYX802_04320
MBAMbar_A2344
MBYMSBRM_1462
MBWMSBRW_2399
MBARMSBR2_0939
MBAKMSBR3_1080
MACMA_1901(adh)
MLSMSLAZ_1208
MEFMSWH1_1726
MEQMSWHS_1589
MSJMSSAC_2296
MSZMSSIH_1875
MSWMSSIT_1932
MTHRMSTHT_0422
MTHEMSTHC_0299
MHORMSHOH_1722 MSHOH_1729
MLAMlab_0764
MCHKMchiMG62_10120
MPLMpal_1399 Mpal_1415 Mpal_2770
HLULT972_05845
HALHHTSR_1102
HHSRHSR6_1139
HSUHLASF_2058
HSFHLASA_2092
SALIL593_13055
HUTHuta_2188
HTIHTIA_2052
HALAHrd1104_11655
HSNDV733_06160
HDSHSR122_2982(tdh3)
HARCHARCEL1_11955
HDOMUK72_17490
NMGNmag_0548
HRUHalru_1322
HLCCHINAEXTREME08015
NAJB1756_11925
NBGDV706_04505
NASGCU68_08765
SAWLNGM29_10620
THBN186_00385
TCBTCARB_1157
 » show all
Reference
1
  Authors
Hoshino, K.
  Title
Organism producing isopropanol from acetone. V. Enzymological [studies] on the oxidation-reduction of Lactobacillus brevis var. hofuensis. [in Japanese].
  Journal
Nippon Nogei Kagaku Kaishi 34:608-615 (1960)
Reference
2
  Authors
Hoshino, K. and Udagawa, K.
  Title
Organism producing isopropanol from acetone. VI. Isopropanol dehydrogenase and alcohol dehydrogenase of Lactobacillus brevis var. hofuensis. [in Japanese].
  Journal
Nippon Nogei Kagaku Kaishi 34:616-619 (1960)
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.80
IUBMB Enzyme Nomenclature: 1.1.1.80
ExPASy - ENZYME nomenclature database: 1.1.1.80
BRENDA, the Enzyme Database: 1.1.1.80
CAS: 37250-18-3

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