KEGG ENZYME: 1.1.1.82

ENZYME: 1.1.1.82

Entry

EC 1.1.1.82                 Enzyme

Name

malate dehydrogenase (NADP+);
NADP+-malic enzyme;
NADP+-malate dehydrogenase;
malic dehydrogenase (nicotinamide adenine dinucleotide phosphate);
malate NADP+ dehydrogenase;
NADP+ malate dehydrogenase;
NADP+-linked malate dehydrogenase;
malate dehydrogenase (NADP+)

Class

Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor

Sysname

(S)-malate:NADP+ oxidoreductase

Reaction(IUBMB)

(S)-malate + NADP+ = oxaloacetate + NADPH + H+ [RN:R00343]

Reaction(KEGG)

R00343

Substrate

(S)-malate [CPD:C00149];
NADP+ [CPD:C00006]

Product

oxaloacetate [CPD:C00036];
NADPH [CPD:C00005];
H+ [CPD:C00080]

Comment

Activated by light.

History

EC 1.1.1.82 created 1972

Pathway

ec00620

Pyruvate metabolism

ec00710

Carbon fixation in photosynthetic organisms

ec01100

Metabolic pathways

ec01120

Microbial metabolism in diverse environments

Orthology

K00051

malate dehydrogenase (NADP+)

Genes

AJM:

119059285

ATH:

AT5G58330

ALY:

9300640

CRB:

17876624

CSAT:

104726404 104735427 104761929

EUS:	EUTSA_v10013555mg

BRP:	103845258 103851645 103856701

BNA:	106387162 106388230 106420432 106435080 106435756

BOE:	106317800 106326990 106335373

RSZ:	108828026 108842484 108842485 108844945 108847633

THJ:

104824214

CIT:

102622984

CIC:	CICLE_v10031559mg

MINC:

123228376

TCC:

18586537

GRA:

105780485

GHI:	107904294 107943658

GAB:

108457850

DZI:

111310364

EGR:

104421754

GMX:

100782567

GSJ:	114372222 114403577

PVU:	PHAVU_007G140600g

VRA:

106772560

VAR:

108321953

VUN:

114192784

CCAJ:

109805341

APRC:

113871024

MTR:

25484827

TPRA:

123908406

CAM:

101499870

PSAT:

127098517

ADU:

107466651

AIP:

107618478

AHF:	112711491 112776877

LANG:

109335149 109346097

PCIN:

129292881 129312899

FVE:

101299807

RCN:

112174171

PPER:

18785428

PMUM:

103331480

PAVI:

110760803

PDUL:

117617069

MDM:	103402801 103408309

MSYL:

126588000 126628159

PXB:	103937854 103938371 103951716

ZJU:

107413281

MNT:

21391387

CSAV:

115706014

CSV:

101211170

CMO:

103489426

BHJ:

120081316

MCHA:

111010262

CMAX:

111467500

CMOS:

111449691

CPEP:

111801663

RCU:

8271083

JCU:

105648670

HBR:

110646716

MESC:

110619296 110623872

POP:

7479845

PEU:

105130696

PALZ:

118060285

JRE:	108983075 109011340

CILL:

122288086 122301262

QSU:

111992093

QLO:

115957569

TWL:

119988885

VVI:

100247974

VRI:

117929166

SLY:	778287(chMDH)

HAN:	110872415 110894838

ECAD:

122600620

LSV:

111911144

CCAV:

112524411

CSIN:

114321212 114322741

RVL:

131318959

BVG:

104884197

SOE:

110802517

CQI:	110698354 110726180

MOF:

131165452

NNU:	104587331 104604574

MING:

122074587 122081181

TSS:	122651918 122655837

OSA:

4346332

DOSA:

Os08t0562100-01(Os08g0562100)

OBR:

102709764

OGL:

127781530

BDI:

100837587

ATS:

109767185

TDC:	119293070 119298570 119329390 119336111

TAES:

123054367 123097218 123101856 123154897 123159028 123165753

TUA:

125529370

LPER:

127315407

LRD:	124662766 124668670

SBI:	110436993 8057802

ZMA:

542374

SITA:

101754520 101775740

SVS:	117842197 117859844

PVIR:

120679202 120713117

PHAI:

112896482

PDA:

103705497

EGU:

105055621

MUS:

103973387

ZOF:

121984705

DCT:

110099942

PEQ:

110020784

AOF:

109850210

NCOL:

116252083

ATR:

18432968

SMO:	SELMODRAFT_175392 SELMODRAFT_270710

CRE:	CHLRE_09g410700v5

VCN:	VOLCADRAFT_76573

OLU:	OSTLU_42336

OTA:	OT_ostta08g00930

» show all

Reference

1 [PMID:5689906]

Authors

Connelly JL, Danner DJ, Bowden JA.

Title

Branched chain alpha-keto acid metabolism. I. Isolation, purification, and partial characterization of bovine liver alpha-ketoisocaproic:alpha-keto-beta-methylvaleric acid dehydrogenase.

Journal

J Biol Chem 243:1198-203 (1968)

Reference

2 [PMID:4397919]

Authors

Johnson HS.

Title

NADP-malate dehydrogenase: photoactivation in leaves of plants with Calvin cycle photosynthesis.

Journal

Biochem Biophys Res Commun 43:703-9 (1971)
DOI:10.1016/0006-291X(71)90672-3

Reference

3 [PMID:4395182]

Authors

Johnson HS, Hatch MD.

Title

Properties and regulation of leaf nicotinamide-adenine dinucleotide phosphate-malate dehydrogenase and 'malic' enzyme in plants with the C4-dicarboxylic acid pathway of photosynthesis.

Journal

Biochem J 119:273-80 (1970)
DOI:10.1042/bj1190273

Other DBs

ExplorEnz - The Enzyme Database:

1.1.1.82

IUBMB Enzyme Nomenclature:

1.1.1.82

ExPASy - ENZYME nomenclature database:

1.1.1.82

BRENDA, the Enzyme Database:

1.1.1.82

CAS:	37250-19-4

DBGET integrated database retrieval system