Entry
Name
malate dehydrogenase (NADP+);
NADP+-malic enzyme;
NADP+-malate dehydrogenase;
malic dehydrogenase (nicotinamide adenine dinucleotide phosphate);
malate NADP+ dehydrogenase;
NADP+ malate dehydrogenase;
NADP+-linked malate dehydrogenase;
malate dehydrogenase (NADP+)
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
(S)-malate:NADP+ oxidoreductase
Reaction(IUBMB)
(S)-malate + NADP+ = oxaloacetate + NADPH + H+ [RN:
R00343 ]
Reaction(KEGG)
Substrate
Product
Comment
Activated by light.
History
EC 1.1.1.82 created 1972
Pathway
ec00710 Carbon fixation by Calvin cycle
ec01120 Microbial metabolism in diverse environments
Orthology
K00051 malate dehydrogenase (NADP+)
Genes
CSAT : 104726404 104735427 104761929
BRP : 103845258 103851645 103856701
BNA : 106387162 106388230 106420432 106435080 106435756
BOE : 106317800 106326990 106335373
RSZ : 108828026 108842484 108847633
LANG : 109335149 109346097
PCIN : 129292881 129312899
QSA : O6P43_004974 O6P43_008639
MSYL : 126588000 126628159
PXB : 103937854 103938371 103951716
MESC : 110619296 110623872
CILL : 122288086 122301262
CAVE : 132186174 132188038
SLY : 543805(mdh) 778287(chMDH)
SPEN : 107004667 107015062
SSTN : 125844002 125857508
NTA : 107769200 107776723(chMDH) 107778629
SSPL : 121761461 121763643 121791094
CSIN : 114321212 114322741
MING : 122074587 122081181
TDC : 119293070 119298570 119329390 119336111
TAES : 123054367 123097218 123101856 123154897 123159028 123165753
MFLO : 136469665 136477066 136498930 136498931
SITA : 101754520 101775740
PVIR : 120679202 120713117
NCOL : 116252083 116265856
SMO : SELMODRAFT_175392 SELMODRAFT_270710
MIS : MICPUN_104869(NADP-MDH)
MPP : MICPUCDRAFT_57848(NADP-MDH)
» show all
Taxonomy
Reference
Authors
Connelly JL, Danner DJ, Bowden JA.
Title
Branched chain alpha-keto acid metabolism. I. Isolation, purification, and partial characterization of bovine liver alpha-ketoisocaproic:alpha-keto-beta-methylvaleric acid dehydrogenase.
Journal
J Biol Chem 243:1198-203 (1968)
Reference
Authors
Johnson HS.
Title
NADP-malate dehydrogenase: photoactivation in leaves of plants with Calvin cycle photosynthesis.
Journal
Reference
Authors
Johnson HS, Hatch MD.
Title
Properties and regulation of leaf nicotinamide-adenine dinucleotide phosphate-malate dehydrogenase and 'malic' enzyme in plants with the C4-dicarboxylic acid pathway of photosynthesis.
Journal
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.82
ExPASy - ENZYME nomenclature database: 1.1.1.82