| Entry |
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| Name |
D-xylulose reductase;
NAD+-dependent xylitol dehydrogenase;
xylitol dehydrogenase (ambiguous);
erythritol dehydrogenase;
2,3-cis-polyol(DPN) dehydrogenase (C3-5);
pentitol-DPN dehydrogenase (ambiguous);
xylitol-2-dehydrogenase
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| Class |
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
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| Sysname |
xylitol:NAD+ 2-oxidoreductase (D-xylulose-forming)
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| Reaction(IUBMB) |
xylitol + NAD+ = D-xylulose + NADH + H+ [RN: R01896]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
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| Comment |
Also acts as an L-erythrulose reductase.
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| History |
EC 1.1.1.9 created 1961
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| Pathway |
| ec00040 | Pentose and glucuronate interconversions |
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| Orthology |
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| Genes |
| NCS: | NCAS_0J00300(NCAS0J00300) |
| TDL: | TDEL_0C00390(TDEL0C00390) |
| SPAA: | SPAPADRAFT_59053(XYL2.1) SPAPADRAFT_59888(XYL2.2) |
| CAL: | CAALFM_CR10840CA(XYL2) |
| CTEN: | CANTEDRAFT_103058 CANTEDRAFT_115939 |
| CAUR: | CJI96_0000472 CJI96_0001804 |
| NTE: | NEUTE1DRAFT71383(NEUTE1DRAFT_71383) |
| TMN: | UCRPA7_5640 UCRPA7_6056 UCRPA7_7026 UCRPA7_8483 |
| SSCK: | SPSK_01724 SPSK_01795 |
| FGR: | FGSG_04247 FGSG_04922 |
| FPU: | FPSE_03960 FPSE_08741 |
| FPOA: | FPOAC1_006704 FPOAC1_007793 |
| FVN: | FVRRES_07325 FVRRES_08328 |
| FVR: | FVEG_03564 FVEG_10437 |
| FOX: | FOXG_05699 FOXG_11380 |
| NHE: | NECHADRAFT_81006 NECHADRAFT_96600 NECHADRAFT_99030 |
| FFC: | NCS54_00180200 NCS54_00868700 NCS54_01222100 |
| FMU: | J7337_003582 J7337_011713 |
| TRE: | TRIREDRAFT_81271(xdh1) |
| MAJ: | MAA_01247 MAA_08094 MAA_08438 MAA_10698 |
| PCHM: | VFPPC_01326 VFPPC_08769 VFPPC_11095 VFPPC_15454 |
| PLJ: | VFPFJ_02524 VFPFJ_06453 VFPFJ_06519 VFPFJ_10159 |
| PTKZ: | JDV02_004041 JDV02_008894(XYL2) JDV02_009623 JDV02_010303 |
| CFJ: | CFIO01_01721 CFIO01_10019 CFIO01_10801 |
| CHIG: | CH63R_05393 CH63R_10797 |
| ELA: | UCREL1_11318 UCREL1_6767 UCREL1_7418 UCREL1_7517 |
| PFY: | PFICI_04520 PFICI_05411 PFICI_05847 PFICI_10488 PFICI_10680 PFICI_11930 PFICI_12195 PFICI_13596 |
| PSCO: | LY89DRAFT_627171 LY89DRAFT_669699 LY89DRAFT_692458 |
| GLZ: | GLAREA_04650 GLAREA_10937 |
| NFI: | NFIA_098450 NFIA_115270 |
| AOR: | AO090020000647 AO090020000676 AO090038000631 AO090103000393 AO090701000411 |
| ANG: | An05g02260 An08g09380 An12g00030 An15g04610 |
| AFV: | AFLA_004927 AFLA_009114 AFLA_009974 AFLA_009999 |
| ALUC: | AKAW2_60288A AKAW2_80295A AKAW2_80979S AKAW2_81370A |
| ACHE: | ACHE_10088S ACHE_50430S ACHE_60231S ACHE_70571S ACHE_80524A |
| APUU: | APUU_31523S APUU_40899A APUU_50400S APUU_60918S |
| PCS: | Pc12g02470 Pc16g10230 Pc16g10990 Pc21g11540 |
| TRG: | TRUGW13939_02074 TRUGW13939_09269 |
| PNO: | SNOG_11390 SNOG_14172 |
| BZE: | COCCADRAFT_104857 COCCADRAFT_38991 |
| BSC: | COCSADRAFT_250797 COCSADRAFT_40924 |
| BOR: | COCMIDRAFT_34708 COCMIDRAFT_36528 |
| AALT: | CC77DRAFT_1054477 CC77DRAFT_1099313 |
| ARAB: | EKO05_0003626 EKO05_0003745 |
| ZTR: | MYCGRDRAFT_31918 MYCGRDRAFT_70997(MgXDH1) |
| PFJ: | MYCFIDRAFT_85679 MYCFIDRAFT_89205 |
| CBET: | CB0940_00152 CB0940_11633 |
| NPA: | UCRNP2_1001 UCRNP2_5372 UCRNP2_9631 |
| CNE: | CNA01050 CNA02580 CNC06670 |
| CNB: | CNBA1020 CNBA2420 CNBC0530 |
| CNG: | CNAG_00115 CNAG_00269 CNAG_07589 |
| CGI: | CGB_B1280C CGB_B2810C CGB_C0560C |
| TMS: | TREMEDRAFT_43291 TREMEDRAFT_69576 TREMEDRAFT_71743 TREMEDRAFT_73604 |
| TASA: | A1Q1_00129 A1Q1_03829 A1Q1_03910 A1Q1_06087 |
| CCAC: | CcaHIS019_0105810(CcaverHIS019_0105810) CcaHIS019_0203390(CcaverHIS019_0203390) CcaHIS019_0204830(CcaverHIS019_0204830) CcaHIS019_0504670(CcaverHIS019_0504670) CcaHIS019_0601150(CcaverHIS019_0601150) |
| DSQ: | DICSQDRAFT_136749 DICSQDRAFT_86636 |
| SHS: | STEHIDRAFT_127586 STEHIDRAFT_77236 |
| ADL: | AURDEDRAFT_110512 AURDEDRAFT_188788 |
| FME: | FOMMEDRAFT_109815 FOMMEDRAFT_109904 FOMMEDRAFT_135448 FOMMEDRAFT_157646 |
| ABP: | AGABI1DRAFT113352(AGABI1DRAFT_113352) |
| ABV: | AGABI2DRAFT192003(AGABI2DRAFT_192003) |
| SCM: | SCHCO_02612591(SCHCODRAFT_02612591) SCHCO_02621873(SCHCODRAFT_02621873) |
| CPUT: | CONPUDRAFT_137211 CONPUDRAFT_81649 |
| PIF: | PITG_04121 PITG_04983 PITG_04985 PITG_04989 |
| SMW: | SMWW4_v1c27000(ydjJ) |
| AVN: | Avin_16590 Avin_20290 |
| AVL: | AvCA_16590 AvCA_20290 |
| AVD: | AvCA6_16590 AvCA6_20290 |
| PGP: | CUJ91_28825 CUJ91_31810 |
| ATA: | AWN88_04145 AWN88_04450 |
| AGR: | AGROH133_13378 AGROH133_15260 |
| AGT: | EYD00_20235 EYD00_20545 |
| RIR: | BN877_II1327 BN877_II1387 |
| RPUS: | CFBP5875_20460 CFBP5875_20770 |
| RET: | RHE_PE00181 RHE_PE00268 |
| REC: | RHECIAT_PA0000139 RHECIAT_PA0000213 |
| REL: | REMIM1_PD00184 REMIM1_PD00283 |
| REI: | IE4771_PC00128 IE4771_PC00215 |
| RLU: | RLEG12_00990 RLEG12_02890 |
| RGA: | RGR602_PC01011 RGR602_PC01881 |
| RHK: | Kim5_PB00159 Kim5_PB00249 |
| ROY: | G3A56_13120 G3A56_23585 |
| RLN: | J0663_14755 J0663_27655 |
| RBAN: | J2J98_05945 J2J98_25090 |
| RSUL: | N2599_24275 N2599_27695 |
| ARA: | Arad_12135 Arad_7087 Arad_8677 |
| HDI: | HDIA_0690 HDIA_P0059 |
| AUZ: | Sa4125_08210 Sa4125_19590 |
| LIZ: | LGH83_06805 LGH83_08900 |
| PABY: | Ga0080574_TMP197 Ga0080574_TMP496 |
| PYE: | A6J80_09200 A6J80_22280 |
| PBAE: | P8S53_05460 P8S53_16905 |
| BRZ: | CFK38_03210 CFK38_11065 |
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| Reference |
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| Authors |
CHIANG C, KNIGHT SG. |
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| Title |
A new pathway of pentose metabolism. |
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| Journal |
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| Reference |
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| Authors |
HICKMAN J, ASHWELL G. |
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| Title |
A sensitive and stereospecific enzymatic assay for xylulose. |
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| Journal |
J Biol Chem 234:758-61 (1959) |
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| Reference |
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| Authors |
JAKOBY WB, FREDERICKS J. |
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| Title |
Erythritol dehydrogenase from Aerobacter aerogenes. |
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| Journal |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 1.1.1.9 |
| ExPASy - ENZYME nomenclature database: | 1.1.1.9 |
| BRENDA, the Enzyme Database: | 1.1.1.9 |
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