KEGG   ENZYME: 1.1.1.9
Entry
EC 1.1.1.9                  Enzyme                                 
Name
D-xylulose reductase;
NAD+-dependent xylitol dehydrogenase;
xylitol dehydrogenase (ambiguous);
erythritol dehydrogenase;
2,3-cis-polyol(DPN) dehydrogenase (C3-5);
pentitol-DPN dehydrogenase (ambiguous);
xylitol-2-dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
xylitol:NAD+ 2-oxidoreductase (D-xylulose-forming)
Reaction(IUBMB)
xylitol + NAD+ = D-xylulose + NADH + H+ [RN:R01896]
Reaction(KEGG)
R01896
Substrate
xylitol [CPD:C00379];
NAD+ [CPD:C00003]
Product
D-xylulose [CPD:C00310];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
Also acts as an L-erythrulose reductase.
History
EC 1.1.1.9 created 1961
Pathway
ec00040  Pentose and glucuronate interconversions
ec01100  Metabolic pathways
Orthology
K05351  D-xylulose reductase
Genes
PPOI119101951
AHF112804057
SCEYLR070C(XYL2)
SEUBDI49_3597
SPAOSPAR_L01250
KLAKLLA0_D05511g
KMXKLMA_70044(SOR1)
LTHKLTH0G18986g
ZROZYRO0F02552g
NCSNCAS_0J00300(NCAS0J00300)
TDLTDEL_0C00390(TDEL0C00390)
ZMKHG535_0D06020
PPAPAS_chr1-1_0490
DHADEHA2A13992g
PICPICST_86924(XYL2)
PGUPGUG_05726
SPAASPAPADRAFT_59053(XYL2.1) SPAPADRAFT_59888(XYL2.2)
LELPVL30_002352(XYL2)
CALCAALFM_CR10840CA(XYL2)
CTPCTRG_05796
COTCORT_0D00360
CDUCD36_35570(XYL2)
CTEN18245603(PSN45_002369) 18248090(XYL2)
YLIYALI0E12463g
CLUCLUG_02658
CLUSA9F13_07g02013
CAURCJI96_0000472 CJI96_0001804
SLBAWJ20_4946(SOR1)
PKZC5L36_0C05200
BNNFOA43_001579
BBRXBRETT_002160
OPAHPODL_00131
NCRNCU00891
NTENEUTE1DRAFT71383(NEUTE1DRAFT_71383)
SMPSMAC_01577
PANPODANSg09388
PBELQC761_101490(XYL2_2)
PPSDQC762_101490(XYL2_2)
PPSPQC763_101490(XYL2_2)
PPSAQC764_101490(XYL2_2)
TTTTHITE_2120696
MTMMYCTH_2293953
CTHRCTHT_0073860
MGRMGG_01176
PPEIPpBr36_00672
PGRIPgNI_04388
TMNUCRPA7_5640 UCRPA7_6056 UCRPA7_7026 UCRPA7_8483
SSCKSPSK_01724 SPSK_01795
FGRFGSG_04247 FGSG_04922
FPUFPSE_03960 FPSE_08741
FPOAFPOAC1_006704 FPOAC1_007793
FVNFVRRES_07325 FVRRES_08328
FVRFVEG_03564 FVEG_10437
FOXFOXG_05699 FOXG_11380
NHENECHADRAFT_81006 NECHADRAFT_96600 NECHADRAFT_99030
FFCNCS54_00180200 NCS54_00868700 NCS54_01222100
FKRNCS57_00177700 NCS57_01209600
FMUJ7337_003582 J7337_011713
TRETRIREDRAFT_81271(xdh1)
TRRM419DRAFT_26280
MAW19248315(XYL2_2) 19249088(J3458_000801) 90964114(XYL2_6)
MAJMAA_01247 MAA_08094 MAA_08438 MAA_10698
PCHMVFPPC_01326 VFPPC_08769 VFPPC_11095 VFPPC_15454
CMTCCM_03621 CCM_06993
AMUSLMH87_011856
PLJ28884656(PLICBS_005880) 28892276(PLICBS_009973) 90642792(PLICBS_003751) 90643275(PLICBS_007920)
PTKZJDV02_004041 JDV02_008894(XYL2) JDV02_009623 JDV02_010303
VALVDBG_09895
VDAVDAG_06181
CFJCFIO01_01721 CFIO01_10019 CFIO01_10801
CLUPCLUP02_07016
CHIGCH63R_05393 CH63R_10797
SAPOSAPIO_CDS1318
ELAUCREL1_11318 UCREL1_6767 UCREL1_7418 UCREL1_7517
PFYPFICI_04520 PFICI_05411 PFICI_05847 PFICI_10488 PFICI_10680 PFICI_11930 PFICI_12195 PFICI_13596
SSLSS1G_05978
BFUBCIN_05g01030
MBEMBM_06974
PSCOLY89DRAFT_627171 LY89DRAFT_669699 LY89DRAFT_692458
GLZGLAREA_04650 GLAREA_10937
ANIANIA_08109 ANIA_09064
AFMAFUA_7G02550
ACTACLA_065000
NFINFIA_098450 NFIA_115270
AORAO090020000647 AO090020000676 AO090038000631 AO090103000393 AO090701000411
ANGAn05g02260 An08g09380 An12g00030 An15g04610
AFVAFLA_004927 AFLA_009114 AFLA_009974 AFLA_009999
ALUCAKAW2_60288A AKAW2_80295A AKAW2_80979S AKAW2_81370A
ACHEACHE_10088S ACHE_50430S ACHE_60231S ACHE_70571S ACHE_80524A
APUUAPUU_31523S APUU_40899A APUU_50400S APUU_60918S
PCSN7525_002218 N7525_007734 N7525_010653 N7525_010728
PDPPDIP_56650
POUPOX_b02131
TMFEYB26_009603
TRGTRUGW13939_02074 TRUGW13939_09269
CIMCIMG_07715
CPWCPC735_042480
UREUREG_07581
PBLPAAG_08336
PBNPADG_04265
ABEARB_04704
TVETRV_03145
AJEHCAG_04376
BGHBDBG_02009
PNOSNOG_11390 SNOG_14172
PTEPTT_13959 PTT_17847
BZECOCCADRAFT_104857 COCCADRAFT_38991
BSCCOCSADRAFT_250797 COCSADRAFT_40924
BORCOCMIDRAFT_34708 COCMIDRAFT_36528
AALTCC77DRAFT_1054477 CC77DRAFT_1099313
ARABEKO05_0003626 EKO05_0003745
ZTRMYCGRDRAFT_31918 MYCGRDRAFT_70997(MgXDH1)
PFJMYCFIDRAFT_85679 MYCFIDRAFT_89205
FFUCLAFUR5_11880
CBETCB0940_00152 CB0940_11633
BCOMBAUCODRAFT_145706
NPAUCRNP2_1001 UCRNP2_5372 UCRNP2_9631
TMLGSTUM_00005037001
SPO2540119(tms1)
SOMSOMG_02449(tms1)
CNECNA01050 CNA02580 CNC06670
CNBCNBA1020 CNBA2420 CNBC0530
CNGCNAG_00115 CNAG_00269 CNAG_07589
CGICGB_B1280C CGB_B2810C CGB_C0560C
CDEUCNBG_0301 CNBG_0440 CNBG_3919
TMSTREMEDRAFT_43291 TREMEDRAFT_69576 TREMEDRAFT_71743 TREMEDRAFT_73604
TASAA1Q1_00129 A1Q1_03829 A1Q1_03910 A1Q1_06087
CCACCcaHIS019_0105810(CcaverHIS019_0105810) CcaHIS019_0203390(CcaverHIS019_0203390) CcaHIS019_0204830(CcaverHIS019_0204830) CcaHIS019_0504670(CcaverHIS019_0504670) CcaHIS019_0601150(CcaverHIS019_0601150)
TVSTRAVEDRAFT_144293
DSQDICSQDRAFT_136749 DICSQDRAFT_86636
PCOPHACADRAFT_249477
SHSSTEHIDRAFT_127586 STEHIDRAFT_77236
HIRHETIRDRAFT_408174
PSQPUNSTDRAFT_99938
ADLAURDEDRAFT_110512 AURDEDRAFT_188788
FMEFOMMEDRAFT_109815 FOMMEDRAFT_109904 FOMMEDRAFT_135448 FOMMEDRAFT_157646
GTRGLOTRDRAFT_55488
LBCLACBIDRAFT_188827
CCICC1G_00399
ABPAGABI1DRAFT113352(AGABI1DRAFT_113352)
ABVAGABI2DRAFT192003(AGABI2DRAFT_192003)
PCUBJR316_0004665
MPRMPER_03874
MRRMoror_7449
MOREE1B28_007666
SCMSCHCO_02612591(SCHCODRAFT_02612591) SCHCO_02621873(SCHCODRAFT_02621873)
CPUTCONPUDRAFT_137211 CONPUDRAFT_81649
SLASERLADRAFT_461886
WSEWALSEDRAFT_16425
WICJ056_004738
UMAUMAG_02150
PFPPFL1_00406
SGRAEX895_005002
MGLMGL_4135
MRTMRET_3689
MSYMMSY001_1216
PIFPITG_04121 PITG_04983 PITG_04985 PITG_04989
PSOJPHYSODRAFT_310790
KLLBJF97_02915
KLWDA718_25210
SMARSM39_2158
SMACSMDB11_1955
SMWSMWW4_v1c27000(ydjJ)
SERFL085_15315
SERSSERRSCBI_12665
SFGAV650_13745
SSURATE40_010105
SURIJ0X03_10470
SNEMNLX84_13585
SFOZ042_20975
SGLSG0610
SODSant_3108
SLIGGTU79_26695
ETAETA_16670
ERPLJN55_05905
PANTPSNIH1_00765
PERLAC65_11285
KPIEN5580_18905
PLUplu1960
PLUMA4R40_09815
PAYPAU_02204(ydjJ)
PAKHB0X70_10095
PLUICE143_10005
PSIS70_17590
PSXDR96_2471(xyl2)
PSTABGK56_19825
PTHAOI982_05760
PVCG3341_13485
PMAGJI723_13385
MMKMU9_3130
PFQQQ39_16335
AVNAvin_16590 Avin_20290
AVLAvCA_16590 AvCA_20290
AVDAvCA6_16590 AvCA6_20290
ACXAchr_19720
ABERBSR55_14545
SPLSpea_2286
SHLShal_2008
CSACsal_2609
HALFQEN58_01205
HOLHORIV_03610
HAAA5892_17465
KUSB9G99_10290
KMAB9H00_04540
KUYFY550_02190
MARSA8C75_01555
MRZKDW95_14690
SALNSALB1_1584
BMABMAA1076
BMVBMASAVP1_0068
BMLBMA10229_0351
BMNBMA10247_A1235
BMALDM55_4585
BMAEDM78_3785
BMAQDM76_3537
BMAIDM57_11320
BMAFDM51_4751
BMAZBM44_4352
BMABBM45_3476
BPSBPSS1235
BPMBURPS1710b_A0234
BPLBURPS1106A_A1653
BPDBURPS668_A1742
BPSEBDL_4525
BPSMBBQ_4932
BPSUBBN_4664
BPSDBBX_3688
BPZBP1026B_II1310
BPQBPC006_II1646
BPKBBK_5875
BPSHDR55_4057
BPSABBU_4822
BPSOX996_4436
BUTX994_5901
BTEBTH_II1176
BTQBTQ_4460(sorD)
BTJBTJ_5441(sorD)
BTZBTL_3904
BTDBTI_3735
BTVBTHA_3976
BTHEBTN_3757
BTHMBTRA_4457(sord)
BTHADR62_3793
BTHLBG87_3916
BOKDM82_5405
BOCBG90_5203
BUUWS70_23815
BHGI6G56_21825
BUDAQ610_24555
BURBcep18194_B3068
BCMBcenmc03_4382
BCHBcen2424_5797
BCJBCAM0097
BCEOI35_4106
BMULNP80_3465
BCEDDM42_5056
BCONNL30_25000
BSEMWJ12_21085
BMECWJ16_20345
BSTLBBJ41_28420
BARINLX30_22255
BGFBC1003_3828
BYIBYI23_D008410
BUEBRPE67_DCDS10340
BULBW21_5730
BUQAC233_27380
BUMAXG89_35410
BUIAX768_17080
BURKDM992_26890
BPHBphy_6662
BGEBC1002_5589
BFNOI25_5778
BCAIK788_0000121
PARABTO02_06610
PHSC2L64_30455
PTERC2L65_27170
PGPCUJ91_28825 CUJ91_31810
PTSCUJ90_21540
PMEGFNZ07_30215
PEWKZJ38_17355
PBRYNDK50_09780
PSAAQEN71_33850
BUOBRPE64_DCDS03300
CABKNK8_60990
VPEVarpa_4066
VBOCKY39_23015
JAZYQ44_03770
JALBZG29_23780
JSVCNX70_24210
JASFJQ89_13445
JLVG3257_24455
JAHJAB4_048420
JRIP9875_24765
HSEHsero_3396
HHTF506_15925
HRBHrubri_3413
HHFE2K99_17675
HFRG5S34_18730
HEWHBDW_35380
CARELT85_3029
CPRACPter91_2190
MLOmlr4915
MLNA9174_02810
MOPMesop_0570
MAMMesau_00518
MAMOA6B35_10320
MESPC1M53_23435
MHUAMCHK_5976
MJREB229_02855
MERDEB233_02965
CHEAPVE73_08575
PHYLHB779_25075
SMESMc01992
SMKSinme_2575
SMQSinmeB_2355
SMXSM11_chr2680
SMIBN406_02374
SMEGC770_GR4Chr2627
SMELSM2011_c01992
SMERDU99_14035
SMDSmed_0849
SIXBSY16_3535
SKMPZL22_002861
STEGQA637_21165
EAHFA04_27450
ENPJVX98_04820
ATUAtu4318
ATAAWN88_04145 AWN88_04450
AGRAGROH133_13378 AGROH133_15260
ATFAch5_40550
AGTEYD00_20235 EYD00_20545
ALFCFBP5473_20840
ARUIG6M88_21470
AVQHRR99_20775
ASALCFBP5507_17620
RIRBN877_II1327 BN877_II1387
RPUSCFBP5875_20460 CFBP5875_20770
ACUCKZ699_21545
ALEGCFBP4996_22825
RETRHE_PE00181 RHE_PE00268
RECRHECIAT_PA0000139 RHECIAT_PA0000213
RELREMIM1_PD00184 REMIM1_PD00283
REPIE4803_PA00213
REIIE4771_PC00128 IE4771_PC00215
RLEpRL110382(sorD)
RLTRleg2_5833
RLGRleg_6746
RLBRLEG3_04550
RLURLEG12_00990 RLEG12_02890
RTRRTCIAT899_PC03125
RHLLPU83_pLPU83d0057
RGARGR602_PC01011 RGR602_PC01881
RHNAMJ98_PD00279
RPHAAMC79_PB00218
RHXAMK02_PE00279
RHVBA939_19180
RHKKim5_PB00159 Kim5_PB00249
REZAMJ99_PC00280
RHRCKA34_22740
RGRFZ934_25405
RADCO657_29810
ROYG3A56_13120 G3A56_23585
RIIFFM53_029830
RHIDFFM81_029045
RBQJ2J99_27925
RLNJ0663_14755 J0663_27655
RBANJ2J98_05945 J2J98_25090
RRGJ3P73_30055
RLSHB780_08640
RROSD4A92_22545
RAWNE851_03625
RSULN2599_24275 N2599_27695
RLWRlegWSM1455_30475
RRHOPR018_12775
RTUPR017_12805
ARAArad_12135 Arad_7087 Arad_8677
AROB0909_16470
RBWRLCC275e_29340
RHIZQMO80_005431
NGLRG1141_CH41290
NGGRG540_CH41810
NEOCYG48_01485
NENNCHU2750_38160
NPMQEO92_25110
RHTNT26_3942
RFVRFYW14_03974
SHZshn_17180
SOJK6301_21615
SSUMQ9314_26580
KAIK32_04730
BPSNNIK97_18840
STARG3545_21515
LNEFZC33_30715
SNOSnov_0847
APRAG3A50_17140
APOLK9D25_19780
MOCBB934_16540
MTEZHPT29_004235
MLDU0023_23310
BIDBind_2341 Bind_3810
DEQXM25_12530
DEAFPZ08_10345
DNPN8A98_14300
DOYJI749_03685 JI749_07430
YTIFNA67_16250
MHARL1P08_01940
PLEOOHA_1_04233
HDIHDIA_0690 HDIA_P0059
MMEDMame_01904
AUAM673_09200
AALAIGS74_12860
AALMLUX29_14740
AUZSa4125_08210 Sa4125_19590
JIEOH818_14440
LIZLGH83_06805 LGH83_08900
RUTFIU92_21990
RDERD1_3623(xdh)
RLIRLO149_c008420
DSHDshi_0551(xylD)
CMARIMCC12053_2454
TPROGa0080559_TMP340
PABYGa0080574_TMP197 Ga0080574_TMP496
OCDFHY55_12550
PALXGQA70_21540
TRYQF118_16000
RSQRsph17025_3580
CAZTLV780_17855
PDEPden_2163
PYEA6J80_09200 A6J80_22280
PAMNJCM7685_0945
PARREOJ32_15835
PKDF8A10_02985
PPANESD82_13270
PLIAE4191_06355
PMAUCP157_00436
PMEHJWJ88_08030
PSEWJHW44_14965
PSAPJHX88_15880
PAEXJHW48_12565
PALPJHW40_20790
PVERE3U25_23245
PFEOE3U26_11385
RMBK529_018670
DAAAKL17_2146
GFUKM031_17430
SALOEF888_13930
BOOE2K80_03620
LITFPZ52_15435
PPAFI8N54_14075
CMAGCBW24_07745
AMAQGO499_07855
PBAEP8S53_05460 P8S53_16905
GOHB932_3019
GTIFXF46_12505
GFAMKW11_06565
GDIGDI3142
GDJGdia_3230
GXLH845_1385
KEUS101446_00518
ABGAsbog_02193
KBAA0U89_01600
RGIRGI145_12850
ROSCTJ15_23505
RMUCFOB66_14520
COQD9V35_00250
COMMGN303_00435
LCKHN018_18475
RAPRHOA_4598
NGUQN315_12675
RRURru_A0252
RRFF11_01275
TIIDY252_05845
BHAIKJK41_19780
PPOLX809_28040
PMSKNP414_01889
PMQPM3016_2175
PMWB2K_11180
KRSEQG70_00825
RKRI6G21_05420
BFABfae_15800
BRXBH708_03340
BRVCFK39_00415
BGGCFK41_08865
BRZCFK38_03210 CFK38_11065
BSAUDWV08_05395
BKIM4486_05630
BHHBra3105_02415
PBOPACID_04280
AACIASQ49_02920
ACIJJS278_02913
ACQAM609_07020
ACTZCWT12_05870
AVCNCTC10951_00727
ALILD5R93_01605
WIKH8R18_05925
BLJBLD_1700(tdh3)
BLKBLNIAS_00276(tdh3)
BLZBLGT_09010
BADBAD_0317
BADLBADO_0324
BADOBBMN23_0346
BBVHMPREF9228_1701
BBREB12L_1575
BBRVB689b_1676
BBRJB7017_1843
BBRCB7019_1816
BBRSBS27_1628
BBRDBBBR_1646
BKSBBKW_0346
BCATBBCT_0305
BPSCBBPC_0333
BSUEBS3272_08260
BNKKIM372_04980
NABB1sIIB91_01955
CAPCLDAP_13590
KBBccbrp13_11680
SLOMPXH66_01865
AAQWK1X11_009795
BMEISpa11_20300
BGOKPr1d_12100
HBSIPV69_13400
TPITREPR_0134
SFCSpiaf_0415
OCKEXM22_09350
SGPSpiGrapes_2365
 » show all
Reference
1  [PMID:13692998]
  Authors
CHIANG C, KNIGHT SG.
  Title
A new pathway of pentose metabolism.
  Journal
Biochem Biophys Res Commun 3:554-9 (1960)
DOI:10.1016/0006-291x(60)90174-1
Reference
2  [PMID:13654257]
  Authors
HICKMAN J, ASHWELL G.
  Title
A sensitive and stereospecific enzymatic assay for xylulose.
  Journal
J Biol Chem 234:758-61 (1959)
Reference
3  [PMID:13789254]
  Authors
JAKOBY WB, FREDERICKS J.
  Title
Erythritol dehydrogenase from Aerobacter aerogenes.
  Journal
Biochim Biophys Acta 48:26-32 (1961)
DOI:10.1016/0006-3002(61)90511-X
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.9
IUBMB Enzyme Nomenclature: 1.1.1.9
ExPASy - ENZYME nomenclature database: 1.1.1.9
BRENDA, the Enzyme Database: 1.1.1.9
CAS: 9028-16-4

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