KEGG ENZYME: 1.1.2.11

ENZYME: 1.1.2.11

Entry

EC 1.1.2.11                 Enzyme

Name

glucoside 3-dehydrogenase (cytochrome c);
D-glucoside 3-dehydrogenase (ambiguous);
D-aldohexopyranoside dehydrogenase (ambiguous);
D-aldohexoside:cytochrome c oxidoreductase;
hexopyranoside-cytochrome c oxidoreductase

Class

Oxidoreductases;
Acting on the CH-OH group of donors;
With a cytochrome as acceptor

Sysname

a D-glucoside:ferric c-type cytochrome 3-oxidoreductase

Reaction(IUBMB)

a D-glucoside + a ferric c-type cytochrome = a 3-dehydro-D-glucoside + a ferrous c-type cytochrome [RN:R13010]

Reaction(KEGG)

R13010

Substrate

D-glucoside [CPD:C01798];
ferric c-type cytochrome

Product

3-dehydro-D-glucoside [CPD:C22515];
ferrous c-type cytochrome

Comment

This bacterial enzyme acts on D-glucose, D-galactose, D-glucosides and D-galactosides, but the best substrates are disaccharides with a glucose moiety at the non-reducing end. It consists of two subunits, a catalytic subunit that contains an FAD cofactor and an iron-sulfur cluster, and a "hitch-hiker" subunit containing a signal peptide for translocation into the periplasm. A dedicated c-type cytochrome protein serves as an electron acceptor, transferring the electrons from the catalytic subunit to the cell's electron transfer chain. cf. EC 1.1.99.13, glucoside 3-dehydrogenase (acceptor).

History

EC 1.1.2.11 created 2022

Orthology

K26059

glucoside 3-dehydrogenase (cytochrome c) catalytic subunit

Genes

XSA:	SB85_19180

XPR:	MUG10_17350

XAG:	HEP73_01428(mpdB)

SML:

Smlt1189

SMT:

Smal_1042

BUJ:	BurJV3_1030

SMZ:

SMD_1110

STEK:

AXG53_11945

SRH:	BAY15_1184

SLM:	BIZ42_14485

STEN:

CCR98_05535

STEM:

CLM74_05525

STES:

MG068_05155

SINC:

DAIF1_10980(fdhL_1)

SPAQ:

STNY_R11600

STEQ:

ICJ04_05010

PJP:	LAG73_15755

LCP:	LC55x_4887

LGU:	LG3211_4767

LEZ:

GLE_2604

LEM:	LEN_2537(chd)

DJI:	CH75_07965

DJA:	HY57_13800

DTL:	H8F01_20920

DTA:	DYST_01541

LRZ:	BJI69_17815

LPY:	FIV34_01215

LANH:

KR767_15525

SWP:

swp_4566

CBER:

B5D82_17160

THAP:

FNC98_01770

THAT:

H3N35_18680 H3N35_22940

TACT:

SG35_009375 SG35_023955

TVD:	SG34_019850

PAT:

Patl_2686

AMC:	MADE_1002110

AMH:	I633_01895

AMAA:

amad1_01955

AMAL:

I607_01925

AMAE:

I876_02105

AMAO:

I634_02170

AMAD:

I636_01975

AMAI:

I635_01960

AMAG:

I533_01880

AMAC:

MASE_01345

AMB:	AMBAS45_01595

AMG:	AMEC673_01410

AMK:	AMBLS11_01670

ALT:	ambt_16610

AAL:	EP13_01870 EP13_04275

AAUS:

EP12_01845

ASP:	AOR13_3174

ASQ:	AVL57_02915

AAW:	AVL56_01635

ALR:	DS731_00790 DS731_01080 DS731_04930 DS731_16810 DS731_19245

ALE:	AV939_01730 AV939_12230

ALZ:	AV940_01725 AV940_11995

APEL:

CA267_011470 CA267_016770

SALM:

D0Y50_12005 D0Y50_17785

SALK:

FBQ74_01510

GAG:	Glaag_1605 Glaag_3241

GPS:	C427_0563 C427_3053

PMES:

FX988_01543 FX988_04202

LAL:	AT746_00170 AT746_00190

CATT:

OLW01_14215 OLW01_15930

CJA:

CJA_3101

CEB:	B0D95_11535 B0D95_14055

CELL:

CBR65_04570 CBR65_16515

CEK:	D0B88_04270 D0B88_06850

CEG:	D0C16_20350

SDE:

Sde_1033

MKE:	OOT55_08005 OOT55_13610 OOT55_14060 OOT55_15155

MTHD:

A3224_13355

MII:	BTJ40_06390

MCEL:

LPW13_12780

HJA:	BST95_12605

HALC:

EY643_09840

AFUS:

EYZ66_11690

HEL:	HELO_1209(lacA)

HAM:

HALO1164

HHU:	AR456_09955

HOL:	HORIV_53400

HMD:	CTT34_14590

HTT:	HZS52_10680

HPRO:

LMS44_17230

HBH:	E4T21_09670

PSPI:

PS2015_2240

MASW:

AM586_03355

MALI:

EYF70_11180

MUM:	FCL38_07550 FCL38_30260

MFLA:

GO485_02965

MPLI:

E1742_04195

TMJ:	P0M04_23575 P0M04_23650 P0M04_30470

ATU:

Atu4377

ATA:	AWN88_09505

AGR:	AGROH133_06059

ATF:	Ach5_13670

ARO:	B0909_16000

AGT:	EYD00_15670

RIR:	BN877_II0387

RPUS:

CFBP5875_15840

RHV:	BA939_25150

ROY:	G3A56_23800

CAEN:

K5X80_13585

CCR:

CC_1634

CCS:	CCNA_01706

CAK:	Caul_0419 Caul_4606

CSE:

Cseg_2107

CAUF:

CSW63_11550

PZU:

PHZ_c2153

PHB:	HYN04_12575

KVL:

KVU_0018

KRO:	BVG79_p1000152(betA)

PARR:

EOJ32_13365

PLIA:

E4191_21965

PMAU:

CP157_00932(fdhL_2)

NAR:	Saro_1208 Saro_3164

NPP:	PP1Y_Mpl7524

NRE:	BES08_18845

NOV:	TQ38_018475

NOT:	C7W88_20495

NHUM:

PQ457_12920 PQ457_15040 PQ457_16135

SPHK:

SKP52_15880

SPHX:

E5675_02890

SPHU:

SPPYR_0169

SWI:	Swit_1632 Swit_1894

SPHD:

HY78_16100 HY78_17425

SPHI:

TS85_04780

SSAN:

NX02_03565 NX02_06585 NX02_17185

SPAN:

AWL63_13110

SKR:	BRX40_12095

SPLM:

BXU08_06665

SPLK:

AV944_06190

SPHC:

CVN68_02540

SPAU:

DRN02_018095

SPAP:

H3Z74_18100

SPII:

G7077_04545

SSUA:

FPZ54_09165 FPZ54_10765

SBIN:

SBA_ch2_5040

SAER:

NEF64_01065

SQO:	NMP03_05525 NMP03_12815

SCAB:

LZK98_07355

SRAD:

LLW23_11875

SHAN:

PPZ50_10920 PPZ50_13090

SCH:	Sphch_3333

SYA:	A6768_07085 A6768_13410 A6768_22545

SPYG:

YGS_C2P1048

SAMI:

SAMIE_1030100

PHAO:

HF685_05635

SPHS:

ETR14_14330

PMEA:

KTC28_05095

CMAN:

A9D14_17345

NAO:	Y958_05220

NCB:	C0V82_03460 C0V82_18550

ECOG:

FIV45_03575

PAQI:

KW060_10790 KW060_10795 KW060_11095 KW060_12005

OBG:	Verru16b_02225(fdhL_1)

TRS:	Terro_2899

EDA:	GWR55_12280

EDG:	H7846_09460

GAU:

GAU_3131

GPH:	GEMMAAP_07015 GEMMAAP_16030

GGR:	HKW67_03755

GBA:

J421_4769

RMR:	Rmar_1737 Rmar_1738

RMG:	Rhom172_1709

RBAR:

AWN76_003120 AWN76_011750

CPI:	Cpin_3694 Cpin_5415 Cpin_5416

CBAE:

COR50_15745 COR50_15750

CHIT:

FW415_18905

CHIH:

GWR21_07690 GWR21_07695

COY:	HF329_02565 HF329_02570 HF329_06890

CFIL:

MYF79_19425 MYF79_22455 MYF79_22460

CHF:	KTO58_06205 KTO58_06210

NKO:	Niako_4747 Niako_6253 Niako_6254

NSO:	NIASO_01055 NIASO_01200

NIA:	A8C56_01535 A8C56_06475 A8C56_12710

FLA:	SY85_02915

FGG:	FSB75_06040

ARB:	A9P82_10750

AGI:	FSB73_08440

ARAC:

E0W69_018035

ATEE:

K9M52_08845

FLN:

FLA_1527

PSEG:

D3H65_23565 D3H65_23570

PGIN:

FRZ67_10645 FRZ67_10650 FRZ67_10665 FRZ67_13155

PGO:	FSB84_06395

FLS:	GLV81_04305 GLV81_07360 GLV81_07460

LACS:

H4075_20645 H4075_20650

FLC:	KJS93_09385

FLV:	KJS94_07525 KJS94_07530

SEDT:

TEGAF0_18080

HHY:	Halhy_3106 Halhy_5995

PHE:	Phep_1967 Phep_2474 Phep_3645

PEP:	AQ505_03335 AQ505_10185 AQ505_15695 AQ505_19940

PCM:	AY601_0203 AY601_0997 AY601_4788

PSTY:

BFS30_08055 BFS30_19470 BFS30_26085

PGS:	CPT03_09075 CPT03_15285

PEJ:	FYC62_11965

PEK:	FFJ24_015780

PROE:

H9L23_16635

PEX:	IZT61_18805

PMUO:

LOK61_12390

PRK:	H9N25_14945

PSN:	Pedsa_3787

SHG:	Sph21_0176 Sph21_3642

SHT:	KO02_06280

SPHN:

BV902_16590

SMIZ:

4412673_02814

SPSC:

E2P86_07800

SPHZ:

E3D81_06430

SPHE:

GFH32_05590

SPDR:

G6053_11955 G6053_25355

SDJ:	NCTC13534_04012

STHA:

NCTC11429_02580 NCTC11429_04773

SSPI:

I6J01_00810

SMUI:

I6J00_05610

SSIY:

JVX97_15200

SFAE:

MUK51_12665

MUP:	A0256_07355 A0256_12600 A0256_15620

MUC:	MuYL_3026 MuYL_3325

MGOT:

MgSA37_02853 MgSA37_03313(fdhL_2) MgSA37_03314(fdhL_3)

MUH:	HYN43_005565 HYN43_012175

MGIN:

FRZ54_17105 FRZ54_18145 FRZ54_20095

MGK:	FSB76_02735 FSB76_30780

MRUB:

DEO27_005760 DEO27_010820

MGOS:

DIU38_002285 DIU38_011655 DIU38_013890

MMAB:

HQ865_03460

MGIK:

GO620_004285

MDJ:	LLH06_15955

MJJ:	PQO05_12735 PQO05_13045 PQO05_19285

AGD:	FRZ59_13320

OLI:	FKG96_15455 FKG96_24395

SBX:	CA265_15345

CMR:	Cycma_1886

CAMU:

CA2015_1800

BBD:	Belba_3815

EVI:	Echvi_1439 Echvi_1847

EST:	DN752_13360 DN752_22850

ECHI:

FKX85_06875 FKX85_08995

EMAI:

KZP23_07040 KZP23_09360

ALM:	AO498_00475 AO498_05075

MDA:	IPZ59_00950

SLI:	Slin_4690 Slin_4949 Slin_5806 Slin_6563

SRD:	SD10_00445 SD10_22215 SD10_25210

SMON:

AWR27_16620 AWR27_16625 AWR27_22650

SPIR:

CWM47_02710 CWM47_15865 CWM47_23720 CWM47_26275

SPIK:

EXU85_01870 EXU85_20810 EXU85_22445 EXU85_32735

SPIB:

G8759_04845 G8759_27020 G8759_32295

STAE:

HNV11_09320 HNV11_19680

SRHO:

HH216_01220 HH216_07885

PSEZ:

HME7025_00207 HME7025_00599

AANH:

G9X63_05975

ALEN:

G9X62_04725

CHRW:

KA713_18580

RHOZ:

GXP67_09115 GXP67_35085

DFE:	Dfer_2494 Dfer_5724

DSN:	HWI92_09330 HWI92_09775

DYC:	NFI80_02955 NFI80_10510

LBY:

Lbys_3311

RSI:	Runsl_0516 Runsl_3527 Runsl_4138 Runsl_4816

RUN:	DR864_02025 DR864_04755 DR864_08180 DR864_08775 DR864_28700

RUP:	DTQ70_06540 DTQ70_09130 DTQ70_15450 DTQ70_21955

EOL:	Emtol_1002 Emtol_1232 Emtol_2222 Emtol_3083

FAE:	FAES_0842 FAES_1054 FAES_2381 FAES_2795

FIB:	A6C57_11220 A6C57_24360

ALS:	DJ013_04515 DJ013_15115

MAQA:

LAG90_19515 LAG90_19520

HSW:

Hsw_1405

HYM:	N008_14610

HYP:	A0257_21565

HYZ:	AXW84_12440

HNV:	DDQ68_07400

HYJ:	FHG12_16415

HQI:	H9L05_14355

HRS:	HER32_01665

HTS:	HMJ29_14610

HTB:	MTX78_00705

HYK:	O9Z63_10765

PKO:	PKOR_01650

RUF:	TH63_14970

RTI:	DC20_05350

ADD:	HUW48_08360 HUW48_20680

ASWU:

HUW51_03455

MTT:	Ftrac_0843

FBT:	D770_23805 D770_24095

CHK:	D4L85_02680 D4L85_12625 D4L85_28620

GFO:

GFO_1027

GRL:	LPB144_04725

GFL:

GRFL_2906

GRS:	C7S20_13090

FBR:	FBFL15_0127

FGL:	EM308_10765

FAO:	SHINM13_17080

FAN:	GENT5_15870

RBI:	RB2501_02785 RB2501_05705 RB2501_05745

ZPR:

ZPR_2442

FBC:	FB2170_04980 FB2170_10304

MARM:

YQ22_09250 YQ22_09280

MART:

BTR34_09330 BTR34_09360 BTR34_13670

MARB:

CJ263_07190 CJ263_16900

MARE:

EJ994_10475 EJ994_12235 EJ994_12265

CAO:	Celal_1740 Celal_1746

CLY:	Celly_1667

CLH:	IX49_08170

CBAL:

M667_06140 M667_06165

CBAT:

M666_06085 M666_06110

COMN:

PBN93_01740 PBN93_08210

KDI:	Krodi_1255

DOK:	MED134_09706(betA)

DDO:	I597_0709(fdhL)

DOD:	DCS32_05720

ZGA:	ZOBELLIA_1915 ZOBELLIA_1922 ZOBELLIA_2208

MRS:	Murru_1519 Murru_2278

MLT:	VC82_1545 VC82_1552 VC82_1980

MUT:	GVT53_05510 GVT53_12450 GVT53_18280 GVT53_18315

MAQI:

LDL77_09800 LDL77_09835 LDL77_16835

SPON:

HME9304_01715

PTQ:	P700755_001830

POM:	MED152_05190(betA)

PRN:	BW723_01820

POA:	CW731_13180

PHAL:

H9I45_11060

PLIT:

K8354_10530

PBAT:

JL193_08625

WIN:	WPG_1744 WPG_1897

SYI:	SB49_11280

LUL:	LPB138_12920 LPB138_12960

SALT:

AO058_04335 AO058_14870

SMIS:

LDL76_09365 LDL76_11620

AALG:

AREALGSMS7_01562 AREALGSMS7_01568 AREALGSMS7_03131

FEK:	C1H87_15470 C1H87_15485

AUE:	C5O00_04585

AQB:	D1818_06215

AQA:	D1815_01160

AQD:	D1816_00755

EMAR:

D1013_02015 D1013_10290 D1013_17705

MUR:	EQY75_13855 EQY75_13885

AFLA:

FHG64_18435

ANP:	FK178_05975

MESQ:

C7H62_0617

GAA:	HX109_04645 HX109_10085

CAGG:

HYG79_07165 HYG79_07195

LPAL:

LDL79_07765

SINH:

LS482_06890

ASAG:

FGM00_05335 FGM00_16375 FGM00_16405

FLG:	LV716_06580 LV716_06615

FLB:	LV704_07595 LV704_07630

SABU:

MBM09_07600 MBM09_15615

ZSP:	MQE36_03815

FBE:	FF125_17570

FBM:	MQE35_07720 MQE35_07730

CPRV:

CYPRO_1995

» show all

Reference

1 [PMID:6038493]

Authors

Hayano K, Fukui S

Title

Purification and properties of 3-ketosucrose-forming enzyme from the cells of Agrobacterium tumefaciens.

Journal

J Biol Chem 242:3655-72 (1967)

Reference

2 [PMID:838689]

Authors

Nakamura LK, Tyler DD.

Title

Induction of D-aldohexoside:cytochrome c oxidoreductase in Agrobacterium tumefaciens.

Journal

J Bacteriol 129:830-5 (1977)
DOI:10.1128/jb.129.2.830-835.1977

Reference

3 [PMID:3818559]

Authors

Takeuchi M, Ninomiya K, Kawabata K, Asano N, Kameda Y, Matsui K.

Title

Purification and properties of glucoside 3-dehydrogenase from Flavobacterium saccharophilum.

Journal

J Biochem 100:1049-55 (1986)
DOI:10.1093/oxfordjournals.jbchem.a121784

Reference

4 [PMID:2844746]

Authors

Takeuchi M, Asano N, Kameda Y, Matsui K.

Title

Physiological role of glucoside 3-dehydrogenase and cytochrome c551 in the sugar oxidizing system of Flavobacterium saccharophilum.

Journal

J Biochem 103:938-43 (1988)
DOI:10.1093/oxfordjournals.jbchem.a122390

Reference

5 [PMID:8984902]

Authors

Tsugawa W, Horiuchi S, Tanaka M, Wake H, Sode K.

Title

Purification of a marine bacterial glucose dehydrogenase from Cytophaga marinoflava and its application for measurement of 1,5-anhydro-D-glucitol.

Journal

Appl Biochem Biotechnol 56:301-10 (1996)
DOI:10.1007/BF02786960

Reference

6 [PMID:11263965]

Authors

Kojima K, Tsugawa W, Sode K.

Title

Cloning and expression of glucose 3-dehydrogenase from Halomonas sp. alpha-15 in Escherichia coli.

Journal

Biochem Biophys Res Commun 282:21-7 (2001)
DOI:10.1006/bbrc.2001.4511

Reference

7 [PMID:16292530]

Authors

Zhang JF, Zheng YG, Xue YP, Shen YC.

Title

Purification and characterization of the glucoside 3-dehydrogenase produced by a newly isolated Stenotrophomonas maltrophilia CCTCC M 204024.

Journal

Appl Microbiol Biotechnol 71:638-45 (2006)
DOI:10.1007/s00253-005-0201-9

Reference

8 [PMID:28044272]

Authors

Zhang JF, Chen WQ, Chen H.

Title

Gene cloning and expression of a glucoside 3-dehydrogenase from Sphingobacterium faecium ZJF-D6, and used it to produce N-p-nitrophenyl-3-ketovalidamine.

Journal

World J Microbiol Biotechnol 33:21 (2017)
DOI:10.1007/s11274-016-2187-0

Sequence

[ag:AMH93716]

Reference

9 [PMID:29625423]

Authors

Miyazaki R, Yamazaki T, Yoshimatsu K, Kojima K, Asano R, Sode K, Tsugawa W.

Title

Elucidation of the intra- and inter-molecular electron transfer pathways of glucoside 3-dehydrogenase.

Journal

Bioelectrochemistry 122:115-122 (2018)
DOI:10.1016/j.bioelechem.2018.03.001

Sequence

[atu:Atu4377]

Other DBs

ExplorEnz - The Enzyme Database:

1.1.2.11

IUBMB Enzyme Nomenclature:

1.1.2.11

ExPASy - ENZYME nomenclature database:

1.1.2.11

BRENDA, the Enzyme Database:

1.1.2.11

All links

Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (1)   
   KEGG REACTION (1)   
Gene (542)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (541)   
All databases (547)   

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