KEGG   ENZYME: 1.1.3.12
Entry
EC 1.1.3.12                 Enzyme                                 
Name
pyridoxine 4-oxidase;
pyridoxin 4-oxidase;
pyridoxol 4-oxidase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With oxygen as acceptor
Sysname
pyridoxine:oxygen 4-oxidoreductase
Reaction(IUBMB)
pyridoxine + O2 = pyridoxal + H2O2 [RN:R01711]
Reaction(KEGG)
R01711
Substrate
pyridoxine [CPD:C00314];
O2 [CPD:C00007]
Product
pyridoxal [CPD:C00250];
H2O2 [CPD:C00027]
Comment
A flavoprotein. Can also use 2,6-dichloroindophenol as an acceptor.
History
EC 1.1.3.12 created 1972, modified 1976
Pathway
ec00750  Vitamin B6 metabolism
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K18607  pyridoxine 4-oxidase
Genes
MLOmll6785
MLNA9174_14005
MCIMesci_2014
MAMMesau_02077
MESWA9K65_010510
MESMEJ066_21210
MESPC1M53_04640
MHUAMCHK_0406
MJREB229_14120
MERDEB233_10970
OCHCES85_3502(pno)
PLEOOHA_1_03156(pno)
HDIHDIA_0247(pno)
MEYTM49_03740
MMEDMame_00118(pno)
AUZSa4125_23970
CEHCEW89_08875
CONTQ29_16085
PALWPSAL_024180(pno)
HTQFRZ44_40440
HADHFRZ61_38600
CPHYB5808_02080
HUMDVJ78_00575
HEAHL652_14720
 » show all
Reference
1  [PMID:5769992]
  Authors
Sundaram TK, Snell EE.
  Title
The bacterial oxidation of vitamin B6. V. The enzymatic formation of pyridoxal and isopyridoxal from pyridoxine.
  Journal
J Biol Chem 244:2577-84 (1969)
Other DBs
ExplorEnz - The Enzyme Database: 1.1.3.12
IUBMB Enzyme Nomenclature: 1.1.3.12
ExPASy - ENZYME nomenclature database: 1.1.3.12
UM-BBD (Biocatalysis/Biodegradation Database): 1.1.3.12
BRENDA, the Enzyme Database: 1.1.3.12
CAS: 37250-82-1

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