KEGG   ENZYME: 1.1.99.20
Entry
EC 1.1.99.20                Enzyme                                 
Name
alkan-1-ol dehydrogenase (acceptor);
polyethylene glycol dehydrogenase;
alkan-1-ol:(acceptor) oxidoreductase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With unknown physiological acceptors
Sysname
alkan-1-ol:acceptor oxidoreductase
Reaction(IUBMB)
primary alcohol + acceptor = aldehyde + reduced acceptor [RN:R00639]
Reaction(KEGG)
R00639
Substrate
primary alcohol [CPD:C00226];
acceptor [CPD:C00028]
Product
aldehyde [CPD:C00071];
reduced acceptor [CPD:C00030]
Comment
A quinoprotein. Acts on C3-C16 linear-chain saturated primary alcohols, C4-C7 aldehydes and on non-ionic surfactants containing polyethylene glycol residues, such as Tween 40 and 60, but not on methanol and only very slowly on ethanol. 2,6-Dichloroindophenol can act as acceptor. cf. EC 1.1.2.7, methanol dehydrogenase (cytochrome c) and EC 1.1.2.8, alcohol dehydrogenase (cytochrome c).
History
EC 1.1.99.20 created 1989
Pathway
ec00071  Fatty acid degradation
Reference
1
  Authors
Kawai F, Kimura T, Tani Y, Yamada H, Ueno T, Fukami H.
  Title
Identification of reaction-products of polyethylene-glycol dehydrogenase.
  Journal
Agric Biol Chem 47:1669-1671 (1983)
Reference
2
  Authors
Kawai F, Yamanaka H, Ameyama M, Shinagawa E, Matsushita K, Adachi O.
  Title
Identification of the prosthetic group and further characterization of a novel enzyme, polyethylene-glycol dehydrogenase.
  Journal
Agric Biol Chem 49:1071-1076 (1985)
Other DBs
ExplorEnz - The Enzyme Database: 1.1.99.20
IUBMB Enzyme Nomenclature: 1.1.99.20
ExPASy - ENZYME nomenclature database: 1.1.99.20
BRENDA, the Enzyme Database: 1.1.99.20
CAS: 75496-55-8

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