Oxidoreductases;
Acting on diphenols and related substances as donors;
With oxygen as acceptor
BRITE hierarchy

benzenediol:oxygen oxidoreductase

4 benzenediol + O2 = 4 benzosemiquinone + 2 H2O [RN:R00083]

R00083
Reaction

benzenediol [CPD:C01785];
O2 [CPD:C00007]

A group of multi-copper proteins of low specificity acting on both o- and p-quinols, and often acting also on aminophenols and phenylenediamine. The semiquinone may react further either enzymically or non-enzymically.

EC 1.10.3.2 created 1961, deleted 1972, reinstated 1978

1

Dawson, C.R. and Tarpley, W.B.

The copper oxidases.

In: Sumner, J.B. and Myrback, K. (Eds.), The Enzymes, 1st ed., vol. 2, Academic Press, New York, 1951, p. 454-498.

2

Keilin, D. and Mann, T.

Laccase, a blue copper-protein oxidase from the latex of Rhus succedanea.

Nature (Lond) 143:23-24 (1939)

3

Malmstrom, B.G., Andreasson, L.-E. and Reinhammar, B.

Copper-containing oxidases and superoxide dismutase.

In: Boyer, P.D. (Ed.), The Enzymes, 3rd ed., vol. 12, Academic Press, New York, 1975, p. 507-579.

4

Mayer, A.M. and Harel, E.

Polyphenol oxidases in plants.

Phytochemistry 18:193-215 (1979)

5  [PMID:13584395]

NAKAMURA T.

Purification and physico-chemical properties of laccase.

Biochim Biophys Acta 30:44-52 (1958)
DOI:10.1016/0006-3002(58)90239-7

6  [PMID:13618260]

NAKAMURA T.

Stoichiometric studies on the action of laccase.

Biochim Biophys Acta 30:538-42 (1958)
DOI:10.1016/0006-3002(58)90100-8

7  [PMID:14304827]

PEISACH J, LEVINE WG.

A COMPARISON OF THE ENZYMIC ACTIVITIES OF PIG CERULOPLASMIN AND RHUS VERNICIFERA LACCASE.

J Biol Chem 240:2284-9 (1965)

8

Reinhammar, B. and Malmstrom, B.G.

"Blue" copper-containing oxidases.

In: Spiro, T.G. (Ed.), Copper Proteins, Copper Proteins, New York, 1981, p. 109-149.