KEGG   ENZYME: 1.10.3.3
Entry
EC 1.10.3.3                 Enzyme                                 
Name
L-ascorbate oxidase;
ascorbase;
ascorbic acid oxidase;
ascorbate oxidase;
ascorbic oxidase;
ascorbate dehydrogenase;
L-ascorbic acid oxidase;
AAO;
L-ascorbate:O2 oxidoreductase;
AA oxidase
Class
Oxidoreductases;
Acting on diphenols and related substances as donors;
With oxygen as acceptor
Sysname
L-ascorbate:oxygen oxidoreductase
Reaction(IUBMB)
4 L-ascorbate + O2 = 4 monodehydroascorbate + 2 H2O [RN:R00068]
Reaction(KEGG)
R00068
Substrate
L-ascorbate [CPD:C00072];
O2 [CPD:C00007]
Product
monodehydroascorbate [CPD:C01041];
H2O [CPD:C00001]
Comment
A multicopper protein.
History
EC 1.10.3.3 created 1961, modified 2011
Pathway
ec00053  Ascorbate and aldarate metabolism
ec01100  Metabolic pathways
Orthology
K00423  L-ascorbate oxidase
Genes
MPHA105832550
ACEP105619985
PBAR105432294
VEM105564207
DQU106742289
CFO105250792
LHU105667585
PGC109853892
OBO105287676
PCF106787214
NVI100116413 100120120
FCD110847151 110848384 110851898 110853443
ADF107352115
PDAM113682968
SPIS111347093
DGT114525421 114525422
AQU100639961 100641875
ATHAT1G55560(sks14) AT1G55570(sks12) AT3G13390(sks11) AT3G13400(sks13) AT5G21100 AT5G21105
ALY110227744 9310099 9318886 9321031 9327906 9330573
CRB17882409 17883051 17884433 17892942 17893080 17898663 17900640
CSAT104706462 104706463 104709266 104736189 104736191 104742997 104742998 104745583 104745584 104758840 104758841 104765114 104765115 104777798 104777807 104778428 104778429
EUSEUTSA_v10011364mg EUTSA_v10011369mg EUTSA_v10013093mg EUTSA_v10013113mg EUTSA_v10020433mg EUTSA_v10020444mg
BRP103832574 103832576 103845074 103845610 103845611 103845612 103849284 103849761 103849762 103851396 103859514 103859515 103870173 103870175 103871036
BNA106345408 106350985 106359433 106359434 106369762 106371691 106375059 106375092 106377433 106377531 106386012 106389117 106393580 106393581 106395302 106421222 106421264 106421363 106421364 106425675 106425805 106426913 106435560 106440590 106440591 106441748 106441749 106452323 106452325 111198020 111204782 111213563 111216205
BOE106293693 106293779 106295159 106313036 106318689 106318690 106318999 106323158 106327666 106332637 106334144 106335418 106335419
RSZ108807327 108810048 108814529 108814726 108815813 108819100 108820490 108821174 108821280 108826114 108859138 108859139 108859782 108862804
THJ104799585 104810309 104810962 104822685 104822686
CPAP110809526 110809584 110810676
CIT102619158 102622926
CICCICLE_v10014733mg CICLE_v10018007mg
PVY116122674 116142154
MINC123201810 123208609 123226472
TCC18589565 18589568 18590851
GRA105783514 105783515 105783516 105783517 105785652 105792378 105793576
GHI107893726 107942731 107942799 107942800 107943178 107962792 121212625 121212627 121212628 121212629 121225277 121225279 121225280
GAB108451244 108452553 108452650 108452667 108452670 108452686 108464786 108466852 108469892 108487771
DZI111285523 111286542 111302378 111304036 111304305
EGR104421412 104423768 104423769 104433749 104433751 104433921 104451286
GMX100776011 100782413 100808812 100810107 100810636 100812197 102666289 547647(AO)
GSJ114381896 114382306 114384252 114402378 114402561 114403052 114403173 114419828 114419830
PVUPHAVU_001G269100g PHAVU_001G269200g PHAVU_002G101700g PHAVU_002G101800g PHAVU_006G011600g PHAVU_006G011700g PHAVU_008G206900g
VRA106763261 106766113 106767378 106767381 106767461 106774704 106775049 106778285
VAR108320002 108320003 108320751 108320752 108327604 108336539 108340690
VUN114163377 114177389 114177516 114178993 114179608 114179710 114188126 114188718 114195433
CCAJ109791759 109792950 109793185 109798036 109798450 109799037 109801574 109803478 109803687
APRC113846395 113849073 113855822 113858057 113859049 113859083
MTRMTR_3g078700 MTR_3g078730 MTR_3g078740 MTR_3g083390 MTR_3g083400 MTR_3g083410 MTR_3g083430 MTR_3g083440 MTR_3g083450 MTR_4g083190 MTR_4g083210
CAM101495562 101511136 101514053 101514709
LJALj2g3v2136010.1(Lj2g3v2136010.1) Lj3g3v3261440.1(Lj3g3v3261440.1) Lj4g3v0669660.1(Lj4g3v0669660.1) Lj4g3v0669710.1(Lj4g3v0669710.1) Lj6g3v0215810.1(Lj6g3v0215810.1) Lj6g3v0227360.1(Lj6g3v0227360.1) Lj6g3v1028660.1(Lj6g3v1028660.1) Lj6g3v1028700.1(Lj6g3v1028700.1)
ADU107472133 107481413 107481423 107481424 107482474 107483946 107483949 107483950 107489332 107496738
AIP107609914 107616629 107627590 107633938 107634769 107634770 107636273 107637689 107638335 110271475
AHF112702168 112720309 112734156 112734158 112734159 112740846 112741915 112741916 112741917 112764247 112789707 112791994 112791995 112791996 112795565 112796630 112796633 112796634
LANG109330592 109331691 109331912 109332114 109344096 109344097 109344964 109349522 109349587
FVE101298449 101300995 101306047
RCN112167001 112168216 112191581 112194304
PPER18772581 18772834 18775169
PMUM103319513 103319616 103319734 103319834 103330351
PAVI110746201 110758991 110758992
PDUL117632137 117632151 117632192 117632202
MDM103423174 103437331 103437332 103448151 114819401
PXB103931457 103931458 103937379 103964981 103965445
ZJU107410413 107410414 107410428 107419354 107419355
MNT112090610 21388637 21388638 21405336
CSV101206777 101211152 101215231 101217209 101221409 101221649 105435332 116403253
CMO103483330 103491644 103491682 103492477(ao3) 103492478(2C07) 103492479 103504343
BHJ120071048 120071718 120071747 120083573 120088038 120088887
MCHA111008621 111021193 111021199 111024072
CMAX111466657 111472953 111483759 111483763 111485412 111490929 111490931 111490934 111495278
CMOS111431626 111436167 111447934 111448771 111448776 111459149 111459150 111459617 111461608
CPEP111777633 111780743 111783409 111793728 111795014 111795016 111796199 111796200 111800229
RCU8271149 8282139 8282140
JCU105629313 105641014 105641022
HBR110632265 110657171 110673626 110673636
MESC110602716 110602748 110610314 110611540 110612449 110626904
POP7457680 7463558 7467963 7478578 7483226
PEU105112161 105126061 105138917 105142272 105142273
PALZ118032382 118032746 118032748 118046977 118062593
JRE108986886 108986893 108987823 108990008
QSU112026054 112036028 112036047
QLO115974362 115974599 115974675 115976749
TWL119980103 119991695 119993855 119996513 119997947 120001683
VVI100251280 100854648 100854827
VRI117910508 117917127
SLY101251411 101253411 101254961 101258916 101263934 101266911
SPEN107003297 107004828 107010225 107012865 107013548 107013895 107019029
SOT102583165 102586624 102589681 102590477 102593165 102596414 102598499 102600371
SSTN125841479 125844170 125844399 125850802 125853317 125857498 125867539 125867701 125869410
CANN107838688 107851491 107851565 107851656 107875512
NTA107763932 107766889 107767669 107773574(ntp101) 107780851 107780962 107798131 107807245 107808172 107814848 107815818(ntp201) 107826841(AAO) 107829710(ntp805) 107832494
NSY104214996 104217594 104223280 104223542 104223698 104233650 104249139
NTO104085910 104088765 104089230 104095887 104104897 104112029 104115662 104117224
NAU109210903 109211953 109215608 109218954 109218986 109225318 109237512 109241711
INI109148570 109148813 109152203 109159750 109175336 109175337
ITR116002889 116002911 116004932 116015631 116017225 116017404 116026100
SIND105161178 105163722 105170577 105170621 105170622 105170623 105170624 105170625
OEU111371401 111378276 111396530 111408228 111412906
EGT105955477 105955642 105956035 105963214 105963215 105972654
SSPL121746770 121749749 121751746 121757384 121763006 121765060 121778707 121781115 121783798 121786430 121787522 121789464
HAN110890477 110908650 110912888
ECAD122592697 122605825
LSV111884547 111898628 111911180
CCAV112501855 112504555
DCR108195383 108199574 108202009 108205281 108206205 108224123
CSIN114266555 114283398 114323084
BVG104890152 104890153 104903081
SOE110774889 110783255 110783270
CQI110701026 110701028 110711978 110736008 110736359 110740325
NNU104590804 104593517 104607198
MING122064649 122064650 122064893 122067521
TSS122641387 122649950 122650032 122655806 122655807
PSOM113309220 113310010 113310064 113310926 113311037 113311038 113321946 113321997 113322601 113324432 113324433 113358394
NCOL116252180 116253900 116254298 116263217
OSA4327488 4339141 4341335 4341337
DOSAOs01t0816700-01(Os01g0816700) Os05t0485800-00(Os05g0485800) Os06t0567200-01(Os06g0567200) Os06t0567900-01(Os06g0567900)
OBR102702982 102704421 102718659 102718934
BDI100828749 100834602 100835816 100835828
ATS109747493 109761427 109770983 109776669
TDC119269387 119277380 119308384 119312162 119329395 119329827 119337311 119339323
TAES123062413 123079553 123094405 123148029 123148031 123155476 123160095 123160290 123165322 123169232 123171311 543019
TUA125521674 125536409 125548762
SBI8055293 8064152 8076742 8076887
ZMA100194388 100273169 100285297 100285407 100285598
SITA101761454 101762191 101773103 101773513
SVS117850578 117853211 117853918 117855816
PVIR120667429 120670572 120670590 120675521 120698327 120703719 120710778
PHAI112887047 112888607 112892206
PDA103702183 103705900 103709578 103709696 103717889
EGU105044886 105046055 105047975 105052352 105057246
MUS103969432 103971537 103972366 103974310 103978083 103984189 103986213 103991220 103993434 103994093 103996975 103998252 104000025
DCT110102783 110109026 110109027 110113582
PEQ110020259 110036211 110036212
AOF109828753 109838325 109841557 109846797
ATR18428785 18440314 18448195
SMOSELMODRAFT_104957 SELMODRAFT_123038
PPP112279727 112280552 112281351 112293195 112293700
CRECHLRE_01g031500v5
MNGMNEG_8946
CSLCOCSUDRAFT_64152
CVRCHLNCDRAFT_137662
CCPCHC_T00009050001
SMPSMAC_03279
MGRMGG_09102
FGRFGSG_02330 FGSG_03507
FPUFPSE_03793 FPSE_12191
FVRFVEG_11948
FOXFOXG_03923 FOXG_22464 FOXG_22466
NHENECHADRAFT_70605 NECHADRAFT_82321
MAWMAC_05769
MAJMAA_01731
CFJCFIO01_00674 CFIO01_02193
ELAUCREL1_10277 UCREL1_9313
PFYPFICI_06862
GLZGLAREA_10474
TMFPMAA_062880
PBNPADG_07092
BGHBDBG_05624
PNOSNOG_10837
BSCCOCSADRAFT_106719
ZTRMYCGRDRAFT_35451 MYCGRDRAFT_42222
NPAUCRNP2_4117 UCRNP2_7111
SHSSTEHIDRAFT_98367(Shmco3)
HIRHETIRDRAFT_181064(HaMCO3)
WSEWALSEDRAFT_56081(Wsmco3)
UMAUMAG_05548
PFPPFL1_05105
PGRPGTG_17514 PGTG_18049 PGTG_18054
MLRMELLADRAFT_23711 MELLADRAFT_48734 MELLADRAFT_90334
MBRMONBRDRAFT_26986
SREPTSG_10043
FCYFRACYDRAFT_137507 FRACYDRAFT_181250 FRACYDRAFT_206397 FRACYDRAFT_235172
SPARSPRG_01703
DZEDd1591_1407
DICDpoa569_001155
XFAXF_2677
XFTPD_2039
XFMXfasm12_2231
XFNXfasM23_2141
XFFXFLM_04690
XFLP303_12325
XFSD934_00395
XFHXFHB_12445
XTWAB672_10630
XBCELE36_06445
PCIPCH70_42250
MPSYCEK71_08100
MMAIsS8_0210 sS8_2506
MHUAMCHK_12935
SKTIGS68_31695
CYJCyan7822_5777
MPROBJP34_20605
 » show all
Reference
1  [PMID:13787201]
  Authors
YAMAZAKI I, PIETTE LH
  Title
Mechanism of free radical formation and disappearance during the ascorbic acid oxidase and peroxidase reactions.
  Journal
Biochim Biophys Acta 50:62-9 (1961)
DOI:10.1016/0006-3002(61)91060-5
Reference
2
  Authors
Stark, G.R. and Dawson, C.R.
  Title
Ascorbic acid oxidase.
  Journal
In: Boyer, P.D., Lardy, H. and Myrback, K. (Eds.), The Enzymes, 2nd ed., vol. 8, Academic Press, New York, 1963, p. 297-311.
Reference
3  [PMID:1548698]
  Authors
Messerschmidt A, Ladenstein R, Huber R, Bolognesi M, Avigliano L, Petruzzelli R, Rossi A, Finazzi-Agro A
  Title
Refined crystal structure of ascorbate oxidase at 1.9 A resolution.
  Journal
J Mol Biol 224:179-205 (1992)
DOI:10.1016/0022-2836(92)90583-6
Other DBs
ExplorEnz - The Enzyme Database: 1.10.3.3
IUBMB Enzyme Nomenclature: 1.10.3.3
ExPASy - ENZYME nomenclature database: 1.10.3.3
BRENDA, the Enzyme Database: 1.10.3.3
CAS: 9029-44-1

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