KEGG ENZYME: 1.13.11.10

ENZYME: 1.13.11.10

Entry

EC 1.13.11.10               Enzyme

Name

7,8-dihydroxykynurenate 8,8a-dioxygenase;
7,8-dihydroxykynurenate oxygenase;
7,8-dihydroxykynurenate 8,8alpha-dioxygenase;
7,8-dihydroxykynurenate:oxygen 8,8a-oxidoreductase (decyclizing)

Class

Oxidoreductases;
Acting on single donors with incorporation of molecular oxygen (oxygenases);
With incorporation of two atoms of oxygen

Sysname

7,8-dihydroxykynurenate:oxygen 8,8a-oxidoreductase (ring-opening)

Reaction(IUBMB)

7,8-dihydroxykynurenate + O2 = 5-(3-carboxy-3-oxopropenyl)-4,6-dihydroxypyridine-2-carboxylate [RN:R03253]

Reaction(KEGG)

R03253

Substrate

7,8-dihydroxykynurenate [CPD:C01111];
O2 [CPD:C00007]

Product

5-(3-carboxy-3-oxopropenyl)-4,6-dihydroxypyridine-2-carboxylate [CPD:C05641]

Comment

Requires Fe2+.

History

EC 1.13.11.10 created 1965 as EC 1.13.1.10, transferred 1972 to EC 1.13.11.10

Pathway

ec00380

Tryptophan metabolism

Reference

Authors

Kuno S, Tashiro M, Taniuchi H, Horibata K, Hayaishi O, Seno S, Tokuyama T, Sakan T.

Title

Enzymatic degradation of kynurenic acid.

Journal

Fed Proc 20:3 (1961)

Other DBs

ExplorEnz - The Enzyme Database:

1.13.11.10

IUBMB Enzyme Nomenclature:

1.13.11.10

ExPASy - ENZYME nomenclature database:

1.13.11.10

BRENDA, the Enzyme Database:

1.13.11.10

CAS:

9029-58-7

All links

No link information was found.

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