Entry |
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Name |
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Class |
Oxidoreductases;
Acting on single donors with incorporation of molecular oxygen (oxygenases);
With incorporation of two atoms of oxygen
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Sysname |
3,4-dihydroxy-L-phenylalanine:oxygen 2,3-oxidoreductase (recyclizing)
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Reaction(IUBMB) |
L-dopa + O2 = 5-(L-alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde [RN: R02076]
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Reaction(KEGG) |
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Substrate |
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Product |
5-(L-alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde [CPD: C04797]
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Comment |
The intermediate product undergoes ring closure and oxidation, with NAD(P)+ as acceptor, to stizolobinic acid. The enzyme requires Zn2+.
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History |
EC 1.13.11.30 created 1978
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Pathway |
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Reference |
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Authors |
Saito K, Komamine A. |
Title |
Biosynthesis of stizolobinic acid and stizolobic acid in higher plants. An enzyme system(s) catalyzing the conversion of dihydroxyphenylalanine into stizolobinic acid and stizolobic acid from etiolated seedlings of Stizolobium hassjoo. |
Journal |
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Reference |
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Authors |
Saito K, Komamine A. |
Title |
Biosynthesis of stizolobinic acid and stizolobic acid in higher plants. |
Journal |
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Other DBs |
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