KEGG   ENZYME: 1.13.11.37
Entry
EC 1.13.11.37               Enzyme                                 
Name
hydroxyquinol 1,2-dioxygenase;
hydroxyquinol dioxygenase;
benzene-1,2,4-triol:oxygen 1,2-oxidoreductase (decyclizing);
benzene-1,2,4-triol:oxygen 1,2-oxidoreductase (ring-opening)
Class
Oxidoreductases;
Acting on single donors with incorporation of molecular oxygen (oxygenases);
With incorporation of two atoms of oxygen
Sysname
hydroxyquinol:oxygen 1,2-oxidoreductase (ring-opening)
Reaction(IUBMB)
hydroxyquinol + O2 = maleylacetate [RN:R04061]
Reaction(KEGG)
R04061;
(other) R03891
Substrate
hydroxyquinol [CPD:C02814];
O2 [CPD:C00007]
Product
maleylacetate [CPD:C02222]
Comment
An iron protein. Highly specific; catechol and pyrogallol are acted on at less than 1% of the rate at which hydroxyquinol is oxidized.
History
EC 1.13.11.37 created 1989, modified 2013
Pathway
ec00361  Chlorocyclohexane and chlorobenzene degradation
ec00362  Benzoate degradation
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K04098  hydroxyquinol 1,2-dioxygenase
Genes
KMIVW41_06390
EBTEBL_c11380
CEMLH23_12110
CENLH86_11520
EAMEGXP68_22265
PAPPSPA7_3907
PREPCA10_31790
PFUWKF707C_25960
PCQPcP3B5_37680(npcC)
PPUNPP4_21440
PPUDDW66_3576 DW66_3593
PFEPSF113_2031(pcpA) PSF113_2035 PSF113_3444(dio1)
PFNHZ99_07105
PPUUPputUW4_02734
PKCPKB_3292(chqB)
PALKPSAKL28_30840
PPSLBJP27_05915
PUMHGP31_15790
PLALFXN65_15925
PEZHWQ56_18940 HWQ56_18960
PSEPC4K39_2722
PAZEKSS91_15355
ALCOTEC02_08745
ASHAG8E00_11110
GAGGlaag_2383
PMESFX988_00678
GAIIMCC3135_30335(chqB)
HCSFF32_04235
HAKKO116_02895
HAMHALO0126 HALO2442
HSIBOX17_05955 BOX17_13025
HBEBEI_0308(chqB)
HAGBB497_08900
HOLHORIV_70440
HTTHZS52_05525
HTXEKK97_21005
CSTEH3L98_00120
CHROCXB49_05325
RPJN234_22425 N234_22775
REHH16_B0968(pcpA)
CNCCNE_2c17420(catA) CNE_BB1p03460(tcpC) CNE_BB1p12870(pcpA) CNE_BB2p00100(chqB)
CUHBJN34_06480 BJN34_26010 BJN34_28970 BJN34_30600
REUReut_A1587 Reut_B4137
CBWRR42_s2530
CGDCR3_2773(chqB)
CCUPBKK81_23295 BKK81_27535
CUPBKK80_28790 BKK80_33020
CUUBKK79_23905 BKK79_34740
COXE0W60_02735 E0W60_29385
BPRGBP346_A0963
BUTX994_6297(pnpC)
BURBcep18194_A4486
BCMBcenmc03_1327
BCJBCAL1342
BCENDM39_2007 DM39_4144 DM39_6781(pnpC)
BCEWDM40_4058(pnpC)
BCEOI35_1237
BAMBamb_3333
BACBamMC406_3378
BMJBMULJ_05458
BMUBmul_6070
BMKDM80_6521(pnpC)
BMULNP80_5281(pnpC)
BCTGEM_5252
BCEDDM42_367(chqB)
BCEPAPZ15_10465
BPYRABD05_19345
BCONNL30_08950
BDFWI26_16515
BLATWK25_22605
BTEIWS51_01155
BSEMWJ12_06615 WJ12_23730
BPSLWS57_19045
BMECWJ16_21310
BSTLBBJ41_05385 BBJ41_36155
BANNJFN94_19955
BUGBC1001_5757
BGFBC1003_5628
BGDbgla_1g14950 bgla_2g18630
BGOBM43_4098 BM43_5582(pnpC)
BYIBYI23_C005020 BYI23_C010690 BYI23_E003790
BUEBRPE67_CCDS00240 BRPE67_CCDS06510
BUQAC233_06840 AC233_32390
BURKDM992_27845
BPHBphy_5624
BGEBC1002_6195
BPXBUPH_02467 BUPH_06038
BPYBphyt_4110
BUZAYM40_28695 AYM40_29855
BFNOI25_124(pnpC)
BCAIK788_0000211 K788_0005293
PSPWBJG93_11795 BJG93_33880
PARABTO02_06690
PARBCJU94_26715
PHSC2L64_24285 C2L64_28360 C2L64_40540 C2L64_49335
PTERC2L65_19190 C2L65_20150 C2L65_23795
PGPCUJ91_07355 CUJ91_25110
PTSCUJ90_31530
PCAFDSC91_001049 DSC91_003620
PMEGFNZ07_23640
PTROG5S35_15155
PACPFAZ97_24900 FAZ97_34765
PEWKZJ38_17255 KZJ38_28510
PPKU875_17305
PPNODA70_09450
PPNMLV28_21360
PRBX636_17110
PSPUNA29_21265
PNRAT302_00100
PCOMNTU39_07980
CABASBC2_61000(chqB) SBC2_61880(npcC)
BUOBRPE64_CCDS00240
BOHAKI39_06590
AXYAXYL_04213
AISBUW96_05140
ACHRC2U31_29965
PUDG9Q38_00545 G9Q38_13405
PIGEGT29_02970 EGT29_18370 EGT29_27115
PARKLSG25_17890
RHYRD110_23655
RHFEUB48_01185
POLBpro_2064
AAAAcav_4141
VEIVeis_4613
DACDaci_3128
VAPVapar_5310 Vapar_5652 Vapar_6138
VPEVarpa_5077 Varpa_5342
VPDVAPA_2c02420(chqB) VAPA_2c10390
VBOCKY39_11265
VAMC4F17_23620
LIHL63ED372_01214(npcC)
HYRBSY239_463
HYBQ5W_09245 Q5W_10810
HYCE5678_13040
HYNF9K07_13415
DIHG7047_13050
ATERMW290_00350
HSEHsero_3722
HSZACP92_18555
HRBHrubri_3690
HEEhmeg3_15060
HHFE2K99_18940
HFRG5S34_20280
LCHLcho_0834
THKCCZ27_18285
MLNA9174_15410 A9174_15460
MCIMesci_5341
MAMOA6B35_10150 A6B35_10200 A6B35_30250
MESWA9K65_029185 A9K65_029235
MJREB229_15610 EB229_15660
MESOBSQ44_19305 BSQ44_19355
HOEIMCC20628_03226
RPODE0E05_06005 E0E05_06055
NIYFQ775_05320 FQ775_05365
SMIBN406_06712(chqB)
SIXBSY16_5879 BSY16_5887
SAMESAMCFNEI73_pC1518
EADOV14_a0023
ESJSJ05684_b42860
EAKEKH55_4634 EKH55_4642
ARAArad_7159
AGRAGROH133_08582
ATFAch5_23960
AVIAvi_7443
AGCBSY240_3579 BSY240_3582 BSY240_3590
AROB0909_00305
REPIE4803_PC00120
REIIE4771_PD00120
RLTRleg2_5728
RLGRleg_5533
RLBRLEG3_03180 RLEG3_09685
RLURLEG12_02390
RIRBN877_p0369
RHLLPU83_3292 LPU83_3301
RGARGR602_PC02264
RHKKim5_PC00123
RJGCCGE525_27635
RHRCKA34_21585
RGRFZ934_22060 FZ934_22100
RADCO657_29300
ROYG3A56_13325
RIIFFM53_025685
RHIDFFM81_029530
RBQJ2J99_28420
RLNJ0663_26260 J0663_26300
RRGJ3P73_26405 J3P73_27940 J3P73_27980 J3P73_29815
RROSD4A92_03070 D4A92_03085
SHZshn_17050 shn_17090
SOJK6301_14530
ABAWD5400_18550
BJAbll2679(bll2679)
BJUBJ6T_64400 BJ6T_69650
BJPRN69_31210 RN69_33790
BRABRADO2272
BRSS23_46820 S23_51990
AOLS58_16190 S58_51450
BRCBCCGELA001_12555 BCCGELA001_14840
BRADBF49_1393 BF49_1887
BICLMTR13_29185 LMTR13_34060
BROBRAD285_4882 BRAD285_6477
BRKCWS35_17195 CWS35_17620
BOTCIT37_37020 CIT37_39575
BRQCIT40_08495 CIT40_11000
BGQX265_19900 X265_26860
BGZXH91_25110
BSYMCIT39_07645 CIT39_10010
BBETF8237_03685 F8237_06010
BARHWN72_15370 WN72_18055
BVZBRAD3257_5389(chqB) BRAD3257_5909(chqB)
BELBE61_72290
BDGLPJ38_17055 LPJ38_19270
BSEPHAP48_0029870
BQBJ4P68_0031145
RPBRPB_3255
TRBHB776_14820 HB776_16380 HB776_17545
BOPAXW83_24115
BVVBHK69_15985 BHK69_29690 BHK69_30645
BOIBLM15_12150
BOFFQV39_05470
XDIEZH22_27585
AZCAZC_1414
STARG3545_26745
LNEFZC33_07630 FZC33_07670
MNOMnod_0748
METXA3862_04725
MINDmvi_53100
MOCBB934_02275
CHELAL346_10240
RHZRHPLAN_08540
PHLKKY_341 KKY_96
DEAFPZ08_02910
DEVOH4N61_05190
PLEOOHA_1_04030(npcC_1) OHA_1_04040(npcC_2)
MAADAZF01_21440 AZF01_21760
MMEDMame_00357(chqB)
MLUTJET14_22370
AUAM673_20520
BRND1F64_20715
PSINCAK95_04575 CAK95_16035 CAK95_21865
PPHRAPZ00_19360
LABRCHH27_10665
LABPFJ695_08960
PHRC6569_13325
PSTGE8M01_14525
RUAD1823_11360
RPONG3256_03725
DSHDshi_0961
PGDGal_04184
PPICPhaeoP14_02544
OATOAN307_c31220(pcaH)
OTMOSB_07930(chqB)
OCTFTO60_04065
LEJETW24_15990
LEVETW23_02860
CEHCEW89_05460
MALGMALG_01196
PABYGa0080574_TMP986
SULZC1J03_01280 C1J03_12295
SULDB5M07_18660
AHTANTHELSMS3_00943(chqB)
TGLHFZ77_08235
HATRC74_11955
PPANESD82_09860
TECAKL02_012960
RBGBG454_13020
GEHHYN69_01440
TAWEI545_03215 EI545_04115
PGVSL003B_1105 SL003B_2470
CACTHZ995_04825 HZ995_11475
CMAGCBW24_17170
FAQG5B39_11520
NORFA702_20805
SPHKSKP52_13005(chqB)
SPHOC3E99_15565
SWISwit_4890 Swit_5063
SPHDHY78_16675
STAXMC45_16620
SJPSJA_C1-09540
SINBSIDU_09280
SCHSphch_2527 Sphch_4045
SBDATN00_11090
SPHBEP837_03834(catA)
SCLOSCLO_5000160 SCLO_6000330(hedE)
SAMISAMIE_4000340(hqdE)
SPHJBSL82_04300
ALHG6N82_06050
AAYWYH_01879(npcC)
ROSCTJ15_00580
RMTIAI58_06025
LCKHN018_04180
SRFLHU95_12200
AZLAZL_a08930
ALIAZOLI_p10976
AOZHUE56_29125
SKTIGS68_31315
SMUCJL100_030945
SROEJL101_032850 JL101_033170
MSAMycsm_06636
MGOAFA91_05600
MDXBTO20_24040
MSHGMSG_03203
MFJMFLOJ_00080 MFLOJ_58920
MSTOMSTO_00790
MSIMMSIM_44860
MSAKMSAS_12740
MCOOMCOO_47870
MDFK0O62_00410
MSENK3U95_01970
MPAAMKK62_17300
MSMMSMEG_4041
MSGMSMEI_3946 MSMEI_6531
MSBLJ00_20060 LJ00_33170
MSNLI99_20065 LI99_33175
MSHLI98_20070 LI98_33180
MVAMvan_4404
MCHTMCHIJ_29990(catA_1)
MAUUNCTC10437_00420(chqB_1) NCTC10437_01566(chqB_2)
CGLCgl3056(Cgl3056)
CGBcg3385(catA3)
CGUWA5_1113 WA5_2951(CatA3)
CGTcgR_2941
CGSC624_06625 C624_14990
CGGC629_06625 C629_15000
CGMcgp_1311 cgp_3385(catA3)
CGJAR0_14800
CGQCGLAR1_14655
CGXSB89_14655
CHNA605_00655
CMDB841_00410
CGYCGLY_10700(chqB)
CHMB842_00265
CDXCDES_03625(chqB)
CCJZccrud_05575
CSURN24_1281 N24_3140
CCOECETAM_00265(npcC)
COKCOCCU_00190(npcC1)
CCYCSCMU_34860
BFVC628_15410
NTPCRH09_15170 CRH09_29770
NADNCTC11293_03317(chqB)
RHARHA1_ro02997 RHA1_ro11310
ROPROP_42970
ROAPd630_LPD13005
RBYCEJ39_21865
RHBNY08_15 NY08_5248
RAVAAT18_09305 AAT18_21120
RFAA3L23_03379(npcC)
RRZCS378_24120
RKOJWS14_29270 JWS14_41630
ROZCBI38_00605
GOCCXX93_13580
GAMGII34_02385 GII34_22300
GOILK459_20900
SCBSCAB_12341(catA) SCAB_14131 SCAB_23641
SRCM271_03105 M271_39995
SBHSBI_00376
SDVBN159_7412(chqB)
SCWTU94_32205
SCXAS200_08365
SLEsle_04030(sle_04030)
SGSAVL59_15620
STSIA4E84_33885
SGMGCM10017557_34830
SCADDN051_35325
SLSSLINC_1035
SNRSNOUR_41075
SPUNBFF78_02420
SGEDWG14_00025(chqB_1) DWG14_00034(npcC_1) DWG14_00196(chqB_3) DWG14_01103(npcC_2)
SDXC4B68_05255
SGDELQ87_04785
SCYAEJ357_04125 EJ357_37245
SNQCP978_05655
SHAWCEB94_34820
SFYGFH48_02565 GFH48_03160 GFH48_10075
SAQUEJC51_40050 EJC51_44170 EJC51_45965
SPHVF9278_41175 F9278_42190
SCHACP983_03985
SCOECP976_36300
SBATG4Z16_31345
SBROGQF42_40810
STUIGCM10017668_59550
SFEUIM697_19745
SROIIAG44_37685
SXNIAG42_02970
SLFJEQ17_02165 JEQ17_08030
SDECL3078_39455 L3078_42005
STRIC7M71_022705
FRPAX769_00715
HEAHL652_06835
SUBTKPL76_07455
ARHAHiyo8_03000
ARYATC04_18360
ARNCGK93_11115
ACRYAC20117_12510 AC20117_15390
ARTPE5206_13930
ACHAchl_4566 Achl_4569
PSNINIBR502771_15875
GARAOZ07_17250
GMINMP99_16705
KPLKPaMU14_06555
KRSEQG70_02210
PAEYKUF55_02765
ORZFNH13_06935
BCAUI6G59_09650
NANOG5V58_19730 G5V58_21965
NAROCFH99_24190
NAQUENKNEFLB_03877(npcC)
NROK8W59_17640
PSIMKR76_25510
AEZC3E78_15315
AEFGEV26_15410 GEV26_15505
STRREKD16_15900(chqB)
AGRAAGRA3207_000241 AGRA3207_001766 AGRA3207_005549
NOABKM31_03440
NOWGBF35_04325 GBF35_14110
NCXNocox_40145(npcC)
BSDBLASA_2518(chqB) BLASA_2968(chqB2)
BLAPMVA48_02660
SACGFDZ84_24820
AMDAMED_4854(catA)
AMNRAM_24710
AMMAMES_4795(catA)
AMZB737_4795(catA)
AMYYYIM_23065(chqB)
APRTMUY14_13325
PDXPsed_2225 Psed_2280 Psed_4969
PSEAWY02_04130
PAUTPdca_03800 Pdca_10260(catA_1)
PBROHOP40_28665 HOP40_31480 HOP40_32530
SESPBN6_46850(chqB)
LEDBBK82_44530
SACEGIY23_17035
ACTNL083_5615
AIHAiant_77920
PSUUPsuf_069710
CAICaci_4340
EKEEK0264_05555 EK0264_11155
RMARGBA65_09705
SBAEDSM104329_04997(chqB)
ERZER308_03905
ONIOsc7112_6631 Osc7112_6636
 » show all
Reference
1  [PMID:6539772]
  Authors
Sze IS, Dagley S.
  Title
Properties of salicylate hydroxylase and hydroxyquinol 1,2-dioxygenase purified from Trichosporon cutaneum.
  Journal
J Bacteriol 159:353-9 (1984)
DOI:10.1128/JB.159.1.353-359.1984
Reference
2  [PMID:15772073]
  Authors
Ferraroni M, Seifert J, Travkin VM, Thiel M, Kaschabek S, Scozzafava A, Golovleva L, Schlomann M, Briganti F
  Title
Crystal structure of the hydroxyquinol 1,2-dioxygenase from Nocardioides simplex 3E, a key enzyme involved in polychlorinated aromatics biodegradation.
  Journal
J Biol Chem 280:21144-54 (2005)
DOI:10.1074/jbc.M500666200
  Sequence
Reference
3  [PMID:16232466]
  Authors
Hatta T, Nakano O, Imai N, Takizawa N, Kiyohara H
  Title
Cloning and sequence analysis of hydroxyquinol 1,2-dioxygenase gene in 2,4,6-trichlorophenol-degrading Ralstonia pickettii DTP0602 and characterization  of its product.
  Journal
J Biosci Bioeng 87:267-72 (1999)
DOI:10.1016/S1389-1723(99)80030-9
Other DBs
ExplorEnz - The Enzyme Database: 1.13.11.37
IUBMB Enzyme Nomenclature: 1.13.11.37
ExPASy - ENZYME nomenclature database: 1.13.11.37
UM-BBD (Biocatalysis/Biodegradation Database): 1.13.11.37
BRENDA, the Enzyme Database: 1.13.11.37
CAS: 91847-14-2

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