KEGG ENZYME: 1.13.11.57

ENZYME: 1.13.11.57

Entry

EC 1.13.11.57               Enzyme

Name

gallate dioxygenase;
GalA;
gallate:oxygen oxidoreductase

Class

Oxidoreductases;
Acting on single donors with incorporation of molecular oxygen (oxygenases);
With incorporation of two atoms of oxygen

Sysname

3,4,5-trihydroxybenzoate:oxygen oxidoreductase

Reaction(IUBMB)

3,4,5-trihydroxybenzoate + O2 = (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate [RN:R09565]

Reaction(KEGG)

R09565;
(other) R03550

Substrate

3,4,5-trihydroxybenzoate [CPD:C01424];
O2 [CPD:C00007]

Product

(1E)-4-oxobut-1-ene-1,2,4-tricarboxylate [CPD:C04434]

Comment

Contains non-heme Fe2+. The enzyme is a ring-cleavage dioxygenase that acts specifically on 3,4,5-trihydroxybenzoate to produce the keto-tautomer of 4-oxalomesaconate [1,2].

History

EC 1.13.11.57 created 2011

Pathway

ec00627

Aminobenzoate degradation

ec01120

Microbial metabolism in diverse environments

Orthology

K04099

gallate dioxygenase

Genes

KPN:

KPN_04051

KPU:

KP1_5420

KPM:	KPHS_52210

KPP:

A79E_0056

KPH:	KPNIH24_25975

KPZ:	KPNIH27_24960

KPV:	KPNIH29_25920

KPW:	KPNIH30_26315

KPY:	KPNIH31_25390

KPG:	KPNIH32_27180

KPC:	KPNIH10_25945

KPQ:	KPR0928_25460

KPT:	VK055_3415

KPR:

KPR_0055

KPJ:

N559_0092

KPI:	D364_20710

KPA:	KPNJ1_00059

KPS:	KPNJ2_00060

KPX:	PMK1_01557(galA)

KPB:	FH42_16645

KPNE:

KU54_000280

KPNU:

LI86_00280

KPNK:

BN49_0056(pcaH)

KVA:

Kvar_0048

KPE:

KPK_0043

KPK:	A593_10490

KVD:	KR75_07885

KVQ:	SP68_14485

KQU:	AVR78_04155

KQV:	B8P98_00275

KAR:	LGL98_00265

KLM:	BWI76_14200

ROR:	RORB6_19035

RAO:	DSD31_00315

CRO:

ROD_31621

KAS:	KATP_00600

KLU:	K7B04_17475

IZH:	FEM41_02385

EBU:	CUC76_15870

SPE:

Spro_2096

SMAF:

D781_1923

SRZ:	AXX16_3206

SERM:

CLM71_09535

SQU:	E4343_05725

SFJ:	SAMEA4384070_2156(ligB)

SRHZ:

FO014_00005

SENP:

KHA73_10630

RAH:	Rahaq_2661

RACE:

JHW33_03865

RAA:

Q7S_13255

ROX:	BV494_03530

RVC:	J9880_20285

RBON:

QNM34_13265

RIU:	I2123_10930

RBAD:

H2866_00085

NIG:	C1N62_02350

SERA:

Ser39006_020425

SERQ:

CWC46_20430

EAM:	EAMY_1944(pcaH)

EAY:

EAM_1902

EBI:

EbC_05400

ETO:	RIN69_19390

PANS:

FCN45_11120

PANE:

P6287_11005

TCI:	A7K98_11200

VFL:	AL536_10245

VZI:	G5S32_20255

PCQ:	PcP3B5_13930(galA)

PPU:	PP_2518(glllA)

PPF:

Pput_3200

PPW:	PputW619_2030

PPB:	PPUBIRD1_3165

PPI:

YSA_00530

PPX:

T1E_3395

PPUT:

L483_20160

PPUN:

PP4_26450

PALD:

LU682_018030

PLUL:

FOB45_15920

PEZ:	HWQ56_20110

PGF:	J0G10_16060

PIZ:	LAB08_R36540

PTAI:

ICN73_17205

PSJY:

AA098_11270

PFOU:

OZ911_17840

PDEU:

QEP73_18355

PSIV:

LZ023_13915

PSTT:

CH92_18130

AVN:	Avin_31250

AVL:	AvCA_31250

AVD:	AvCA6_31250

PDEN:

F1C79_11695

ATN:	FM020_08445

SYK:	KDN34_01905

ALR:	DS731_01180

ALTO:

AltI4_17290

HARO:

R50071_30390

CSA:

Csal_0323

MPRI:

MP3633_1414

MFOI:

JSY38_07135

MPON:

MACH16_19660

VFF:	VITFI_CDS3502

PSE:

NH8B_2725

AMAH:

DLM_2050

RSL:	RPSI07_mp1412

RSY:	RSUY_46170(galA)

RSG:	JK151_11985

RME:

Rmet_3709

CCAM:

M5D45_26480

CUPE:

KLP38_23910

CUPP:

CTP10_R59760

BUR:	Bcep18194_C7572

BCEN:

DM39_6585

BCEO:

I35_7835

BMJ:	BMULJ_05486(ligB)

BMU:

Bmul_6041

BMK:

DM80_6492

BMUL:

NP80_5253

BCED:

DM42_7336(ligB)

BUB:

BW23_4779

BDF:	WI26_29680

BTEI:

WS51_29490

BPSL:

WS57_17850

BGD:	bgla_2g01750

BGO:	BM43_6953(ligB)

BYI:	BYI23_D009710

BGP:	BGL_2c21000(ligB)

BPLA:

bpln_2g21110

BURT:

BTHE68_66380

BPH:

Bphy_6377

BCAI:

K788_0005435

PHS:	C2L64_29345

PTER:

C2L65_19030

PTRO:

G5S35_16940

PACP:

FAZ97_23230

PACS:

FAZ98_26605

PSAA:

QEN71_33625

PPAI:

E1956_34555 E1956_36295

PLAD:

PPGU16_52950 PPGU16_81330

PAZZ:

PBP221_37720

BUO:	BRPE64_DCDS10470

CABK:

NK8_62560

BUE:	BRPE67_DCDS11760

BOJ:	CBF45_06980

CDN:	BN940_06091

RHOB:

HTY51_12000

RHOF:

AB3G31_06095

ACK:	C380_00245

ACRA:

BSY15_1204(ligA)

ACIQ:

ACDW_43770

VEI:

Veis_0170

VPE:	Varpa_2578

VPD:	VAPA_2c01480

VAM:	C4F17_02070

VAX:	H7F36_16945

CTES:

O987_18260

CKE:	B5M06_09345

OTK:	C6570_16450(ligA)

DIH:	G7047_15145

ATER:

MW290_13930

RGU:	A4W93_03465

HHF:	E2K99_06675

HEW:	HBDW_12210

MASW:

AM586_11765

MFY:	HH212_24595

MALI:

EYF70_25860

MUM:	FCL38_23490

MFLA:

GO485_19000

PLUE:

EWM63_10065

DUG:	HH213_29575

XYK:	GT347_11010

URU:	DSM104443_02505(galA)

THU:	AC731_013745

THAU:

C4PIVTH_1488

BEBA:

BWI17_14460

BRA:	BRADO1853(ligB)

BBT:	BBta_2174(ligB)

PHL:

KKY_2539

PSIN:

CAK95_21930

PSTG:

E8M01_02555

AEX:	Astex_2404

ASTD:

ATDW_23770

PGV:	SL003B_1110

NRE:	BES08_28870

SSY:	SLG_03330(desB)

ACOB:

P0Y56_06545

ALB:

AEB_P3471

AAY:	WYH_03044(galA)

RGI:	RGI145_21125

ROS:	CTJ15_00885

RMUC:

FOB66_01800

AZS:	E6C72_16025

AZP:	E6C67_16340

MAGX:

XM1_1091

MAGN:

WV31_13615

MICA:

P0L94_13925

PARH:

I5S86_11495

SLAU:

SLA_7098

SHUN:

DWB77_01945(ligB_1)

KSK:	KSE_75140(pcmA)

KIT:	CFP65_0440

KIS:	HUT16_35040(ligA)

AREV:

RVR_8737

PPHP:

VTA80_03100(ligA)

MHOS:

CXR34_05670(ligA)

MOO:	BWL13_00076(ligB)

MRG:	SM116_16195

ART:

Arth_4373

ARTP:

E5206_14135

APN:	Asphe3_42380

CCYC:

SCMU_02410(pcmA)

PEI:	H9L10_00565(ligA)

DCP:	RN607_01885

AMYD:

K1T34_49790

ACTN:

L083_1495

» show all

Reference

1 [PMID:16030014]

Authors

Nogales J, Canales A, Jimenez-Barbero J, Garcia JL, Diaz E

Title

Molecular characterization of the gallate dioxygenase from Pseudomonas putida KT2440. The prototype of a new subgroup of extradiol dioxygenases.

Journal

J Biol Chem 280:35382-90 (2005)
DOI:10.1074/jbc.M502585200

Reference

2 [PMID:21219457]

Authors

Nogales J, Canales A, Jimenez-Barbero J, Serra B, Pingarron JM, Garcia JL, Diaz E

Title

Unravelling the gallic acid degradation pathway in bacteria: the gal cluster from Pseudomonas putida.

Journal

Mol Microbiol 79:359-74 (2011)
DOI:10.1111/j.1365-2958.2010.07448.x

Sequence

[ag:AAN68130]

Other DBs

ExplorEnz - The Enzyme Database:

1.13.11.57

IUBMB Enzyme Nomenclature:

1.13.11.57

ExPASy - ENZYME nomenclature database:

1.13.11.57

UM-BBD (Biocatalysis/Biodegradation Database):

1.13.11.57

BRENDA, the Enzyme Database:

1.13.11.57

DBGET integrated database retrieval system