KEGG ENZYME: 1.13.11.79

ENZYME: 1.13.11.79

Entry

EC 1.13.11.79               Enzyme

Name

aerobic 5,6-dimethylbenzimidazole synthase;
BluB;
flavin destructase

Class

Oxidoreductases;
Acting on single donors with incorporation of molecular oxygen (oxygenases);
With incorporation of two atoms of oxygen

Sysname

FMNH2 oxidoreductase (5,6-dimethylbenzimidazole-forming)

Reaction(IUBMB)

FMNH2 + O2 = 5,6-dimethylbenzimidazole + D-erythrose 4-phosphate + other product(s) [RN:R09083]

Reaction(KEGG)

R09083

Substrate

FMNH2 [CPD:C01847];
O2 [CPD:C00007]

Product

5,6-dimethylbenzimidazole [CPD:C03114];
D-erythrose 4-phosphate [CPD:C00279];
other product(s)

Comment

The enzyme catalyses a complex oxygen-dependent conversion of reduced flavin mononucleotide to form 5,6-dimethylbenzimidazole, the lower ligand of vitamin B12. This conversion involves many sequential steps in two distinct stages, and an alloxan intermediate that acts as a proton donor, a proton acceptor, and a hydride acceptor [4]. The C-2 of 5,6-dimethylbenzimidazole is derived from C-1' of the ribityl group of FMNH2 and 2-H from the ribityl 1'-pro-S hydrogen. While D-erythrose 4-phosphate has been shown to be one of the byproducts, the nature of the other product(s) has not been verified yet.

History

EC 1.13.11.79 created 2010 as EC 1.14.99.40, transferred 2014 to EC 1.13.11.79, modified 2019

Pathway

ec00740

Riboflavin metabolism

ec01100

Metabolic pathways

Orthology

K04719

5,6-dimethylbenzimidazole synthase

Genes

LMB:	C9I47_0274

FAU:	Fraau_1297

DJA:	HY57_01060

DCS:	ISN74_00965(bluB)

DTL:	H8F01_03225(bluB)

DTA:	DYST_00975

VSP:

VS_II1157

VNI:	VIBNI_B0592(bluB)

VCY:	IX92_08570

VCT:	JV59_29945

VGI:	MID13_17510(bluB)

VSL:	LTQ54_18980(bluB)

VOS:	KNV97_03005(bluB)

VCRA:

IS519_19340(bluB)

VLE:	ISX51_17135(bluB)

PAE:

PA1274

PAEV:

N297_1314(bluB)

PAEI:

N296_1314(bluB)

PAU:	PA14_47750

PAP:	PSPA7_4116

PAG:	PLES_40381

PAF:	PAM18_3755

PNC:	NCGM2_2158

PAEB:

NCGM1900_5300

PDK:	PADK2_19275

PSG:	G655_18795

PRP:	M062_06935

PAEP:

PA1S_19535

PAER:

PA1R_gp4881

PAEM:

U769_19385

PAEL:

T223_20630

PAES:

SCV20265_4139

PAEU:

BN889_01358

PAEG:

AI22_14425

PAEC:

M802_1311(bluB)

PAEO:

M801_1313(bluB)

PMY:

Pmen_1752

PMK:

MDS_3110

PRE:	PCA10_18230

PPSE:

BN5_1585(bluB)

PFUW:

KF707C_38840

PALC:

A0T30_08975

PCQ:	PcP3B5_15460(bluB)

PMUI:

G4G71_10050(bluB)

PNT:	G5B91_24770(bluB)

PPAA:

B7D75_18795(bluB)

PPU:	PP_1674(bluB)

PPF:

Pput_4045

PPG:	PputGB1_1273

PPW:	PputW619_1233

PPT:

PPS_1325

PPB:	PPUBIRD1_3943

PPI:

YSA_02431

PPX:

T1E_3648

PPUH:

B479_06405

PPUT:

L483_05925

PPUN:

PP4_40970

PPUD:

DW66_1247 DW66_1609

PFV:	Psefu_1876

PMON:

X969_04500

PMOT:

X970_04475

PPJ:	RK21_03729

POR:	APT59_07125

PMOL:

CLJ08_06225(bluB)

PALD:

LU682_022800(bluB)

PIX:	RIN61_17920(bluB)

PMOS:

O165_016305

PST:	PSPTO_1710

PSB:

Psyr_3679

PSYR:

N018_07015

PSP:	PSPPH_3700

PSAV:

PSA3335_22400

PAMG:

BKM19_021940(bluB)

PCI:	PCH70_37930

PAVL:

BKM03_21205(bluB)

PVD:	CFBP1590__1585

PCAB:

JGS08_06355(bluB)

PCOF:

POR16_06885(bluB)

PTRE:

I9H09_07530(bluB)

PSYI:

MME58_18920(bluB)

PAST:

N015_19445(bluB)

PLIJ:

KQP88_17940(bluB)

PFL:	PFL_4429(bluB)

PPRC:

PFLCHA0_c45020

PPRO:

PPC_4538

PFE:	PSF113_4408(bluB)

PFN:	HZ99_25615

PFO:	Pfl01_1643

PFS:

PFLU_4489

PFC:	PflA506_3794(bluB)

PPZ:	H045_13365

PFB:

VO64_5046

PMAN:

OU5_5263

PTV:	AA957_22380

PCG:	AXG94_08115

PVR:	PverR02_22860

PAZO:

AYR47_29140

POI:	BOP93_18480

PRX:	HRH33_19520(bluB)

PMED:

E3Z27_21250(bluB)

PKR:	AYO71_11110

PMUD:

NCTC8068_03847(bluB)

PTOL:

I7845_20775(bluB)

PFW:	PF1751_v1c39830(bluB)

PFF:	PFLUOLIPICF716280

PFX:	A7318_19165

PEN:

PSEEN1380

PLUL:

FOB45_13295(bluB)

PBA:	PSEBR_a4243

PBC:	CD58_22415

PPUU:

PputUW4_03773(bluB)

PDR:	H681_18005

PSV:	PVLB_06055

PSK:	U771_23370

PKC:

PKB_1569

PCH:	EY04_22480

PCZ:	PCL1606_17510

PCP:	JM49_08710

PCHP:

C4K32_4610

PFZ:	AV641_06130

PLQ:	AA042_03935

PALK:

PSAKL28_12900

PRH:	LT40_06750

PSW:	LK03_21825

PPV:	NJ69_12250

PSES:

PSCI_0381

PSEM:

TO66_23155

PSEC:

CCOS191_1318

PPSY:

AOC04_02665

PSOS:

POS17_4501(bluB)

PFK:	PFAS1_19730

PANR:

A7J50_4169

PPSL:

BJP27_21915

PSET:

THL1_1818

PSIL:

PMA3_21100

PYM:	AK972_4372

PKE:	DLD99_09015(bluB)

PALL:

UYA_09280

PUM:	HGP31_08740(bluB)

POJ:	PtoMrB4_40760

PGG:	FX982_00179

PPSH:

G5J76_08710(bluB)

PGY:	AWU82_01175(bluB)

PLAL:

FXN65_19560(bluB)

PSEJ:

HNQ25_15570(bluB)

PVK:	EPZ47_22480(bluB)

PEZ:	HWQ56_06875(bluB)

PBZ:	GN234_25795(bluB)

PKH:	JLK41_09485(bluB)

PTY:	JWV26_19595(bluB)

PMAO:

PMYSY11_2978(bluB)

PATA:

JWU58_19455(bluB)

PDW:	BV82_4283(bluB)

PZE:	HU754_009765(bluB)

PMOE:

HV782_009240(bluB)

PCAM:

HNE05_10420(bluB)

PSEP:

C4K39_6363

PPII:

QL104_22960(bluB)

PVW:	HU752_025660(bluB)

PTRT:

HU722_0021110(bluB)

PXA:	KSS93_09790(bluB)

PSAM:

HU731_007525(bluB)

PTZ:	HU718_009445(bluB)

PQI:	KH389_20340(bluB)

PSHH:

HU773_008135(bluB)

PXN:	HU772_006285(bluB)

PHV:	HU739_009390(bluB)

PPRG:

HU725_005765(bluB)

PANH:

HU763_006315(bluB)

PASG:

KSS96_20755(bluB)

PFAK:

KSS94_06520(bluB)

PMUY:

KSS95_09350(bluB)

PMAM:

KSS90_06960(bluB)

PAZE:

KSS91_20445(bluB)

PALV:

KSS97_08065(bluB)

PORY:

EJA05_06805(bluB)

PWZ:	J7655_12945(bluB)

PTK:	EXN22_20875(bluB)

PTW:	TUM18999_41240

PZA:	HU749_022435(bluB)

PIE:	HU724_008900(bluB)

PWY:	HU734_007120(bluB)

PTAE:

NCTC10697_01153

PGF:	J0G10_09560(bluB)

PCAV:

D3880_15620(bluB)

PJU:	L1P09_05635(bluB)

PHF:	NLY38_16235(bluB)

PPHN:

HU825_10670(bluB)

PIZ:	LAB08_R44850(bluB)

PPEG:

KUA23_21885(bluB)

PSII:

NF676_08580(bluB)

PSIH:

LOY51_06685(bluB)

PCAS:

LOY40_07030(bluB)

PFIT:

KJY40_09550(bluB)

PASI:

LG197_11470(bluB)

PKM:	PZ739_06290(bluB)

PNB:	NK667_18715(bluB)

PSOA:

PSm6_02370

PTAI:

ICN73_12590(bluB)

PKK:	QQ992_06435(bluB)

PKJ:	Q1W70_17315(bluB)

PHYG:

JTY93_07300(bluB)

PHOM:

KJF94_05205(bluB)

PCHE:

QYM18_16730(bluB)

PCUC:

PSH97_08465(bluB)

PTRL:

OU419_08260(bluB)

PPAE:

LDL65_02610(bluB)

PPAO:

K3169_22350(bluB)

PRHZ:

CRX69_06275(bluB)

PSJY:

AA098_06670

PSKU:

KUIN1_36430

PSA:

PST_1293

PSZ:	PSTAB_1286

PSR:	PSTAA_1325

PSC:	A458_07185

PSJ:	PSJM300_09265

PSH:	Psest_3012

PSTT:

CH92_07715

PSTU:

UIB01_15325

PSED:

DM292_12720(bluB)

PCHL:

LLJ08_14715(bluB)

PKG:	LW136_07670(bluB)

SDEG:

GOM96_15915(bluB)

PZD:	KQ248_12780(bluB)

AVN:	Avin_33110

AVL:	AvCA_33110

AVD:	AvCA6_33110

ACX:	Achr_16200

PBB:	AKN87_04570

HPEG:

EAO82_14965(bluB)

HAES:

LO767_08720(bluB)

PDEN:

F1C79_16355(bluB)

PNN:	KEM63_09670(bluB)

PPHA:

BVH74_15360

PBAU:

OS670_02215(bluB)

MHC:

MARHY0223

MBS:	MRBBS_0221(bluB)

MSR:	AU15_14630

MPQ:	ABA45_00875

MLQ:	ASQ50_09735

MARJ:

MARI_26150(bluB)

MALL:

PBN92_01130(bluB)

MSHE:

MAALD49_02380 MAALD49_05020

MANP:

EHN06_01700(bluB)

KAK:	Kalk_03885(bluB)

SPL:

Spea_0684

SHL:

Shal_0741

SWD:

Swoo_1863

SWP:

swp_4403

SVO:

SVI_0196

SPSW:

Sps_00268

SALG:

BS332_17430

SCAA:

TUM17387_18850

SPSH:

FM037_01080(bluB)

SEUR:

FM038_001095(bluB)

SCHK:

GII14_10995(bluB)

CPS:

CPS_2468

COV:	EKO29_05845(bluB)

CATE:

C2869_01490(bluB)

HMI:	soil367_05765(bluB)

ALKM:

NKI27_12100(bluB)

ASEM:

NNL22_08515(bluB)

MVS:

MVIS_3206

MYA:	MORIYA_4222(bluB)

SPOI:

IMCC21906_01248

SNAN:

I6N98_11875(bluB)

STAW:

NCG89_05515(bluB)

ZAL:	AZF00_14410

OSG:	BST96_12065

HJA:	BST95_13980

HALC:

EY643_08260(bluB)

MCA:

MCA2289

MMT:	Metme_0236

MDN:	JT25_009245

MDH:	AYM39_01740

MKO:	MKLM6_0391

METL:

U737_00615(bluB)

MELL:

IVG45_16690(bluB)

MRP:	NM686_000835(bluB)

MMOT:

QZJ86_00745(bluB)

MAH:	MEALZ_0954(bluB)

MBUR:

EQU24_05370(bluB)

MPSY:

CEK71_07165(bluB)

MMAI:

sS8_1635

MSZE:

MSZNOR_1429(bluB)

MMOB:

F6R98_12905(bluB)

MEIN:

methR_P1912

MOZ:	MoryE10_11370

MESL:

KKZ03_17800(bluB)

MEJ:	Q7A_2235(bluB)

MPIN:

LGT42_007235(bluB)

MMAF:

GCM100_26940

MTHA:

VSX76_11680(bluB)

TSB:	HMY34_13795(bluB)

MPUR:

MARPU_06160

TSY:	THSYN_32055

CJAP:

GWK36_04180(bluB)

HHC:	M911_10240

EBS:	ECTOBSL9_3025

TKM:

TK90_1459

TVR:

TVD_07100

NAX:	HC341_03135(bluB)

SEDS:

AAY24_03460

HCH:

HCH_06460

HAHE:

ENC22_28350(bluB)

HAHH:

O5O45_28220(bluB)

HEL:	HELO_1843(bluB)

HCS:	FF32_00895

HAK:	KO116_01397

HAM:

HALO1452

HHU:	AR456_06965

HALO:

BWR19_06685

HSV:	HNO53_14265(bluB)

HPRO:

LMS44_16005(bluB)

HQD:	K1Y77_12355(bluB)

HBH:	E4T21_09050(bluB)

HBP:	HPTD01_2200

HALF:

QEN58_13810(bluB)

HHAO:

QWG60_11765(bluB)

HASO:

B2G49_02705

HALW:

B6N23_15730(bluB)

HASH:

HXW73_04200(bluB)

HALK:

CUU95_11285(bluB)

HVN:	EI420_14850(bluB)

HOL:	HORIV_49330

HNP:	SR894_14160(bluB)

HTT:	HZS52_11985(bluB)

HTX:	EKK97_15390(bluB)

HAA:	A5892_11705

KUS:	B9G99_14455

KMA:	B9H00_00535

KUY:	FY550_07875(bluB)

MMW:	Mmwyl1_1437

MME:	Marme_3143

MPRI:

MP3633_2603(bluB)

MARD:

IBG28_05965(bluB)

MFOI:

JSY38_03850(bluB)

MPRF:

J8N69_03270(bluB)

MRHI:

KDW99_06260(bluB)

MPON:

MACH16_10100

OAI:	OLEAN_C38190

MARS:

A8C75_13705

MSEC:

LN244_01045(bluB)

MRZ:	KDW95_03240(bluB)

BACZ:

KFF03_02455(bluB)

GSN:	YC6258_01114

OME:	OLMES_4860(bluB)

PLEI:

Q9312_17550(bluB)

OCE:

GU3_05380

OPE:	PU634_12510(bluB)

GBI:	PG2T_14240

GPB:	HDN1F_22590

VFF:	VITFI_CDS3318

CCAH:

DWG20_14555(bluB)

CVI:

CV_1555

CVC:	BKX93_20935

CHRO:

CXB49_14740(bluB)

CHRI:

DK842_00225(bluB)

CHRB:

DK843_05510(bluB)

CRZ:	D1345_11775(bluB)

CHRM:

FYK34_02910(bluB)

CHAE:

CH06BL_24170

PSE:	NH8B_1828 NH8B_2700

AMAH:

DLM_2228

AQS:	DKK66_15345(bluB)

IOD:	EJO50_13765(bluB)

IFL:	C1H71_07940(bluB)

MAER:

DAI18_01080(bluB)

RSO:

RSp0614

RSE:

F504_4611

RPU:	CDC45_20685(bluB)

RNC:	GO999_17115(bluB)

RSL:	RPSI07_mp0498

RSM:	CMR15_mp10570

RSY:	RSUY_38260(bluB)

RPJ:	N234_09705

RIN:	ACS15_1510(bluB)

CNC:	CNE_1c18130(bluB)

CUH:	BJN34_09130

RME:

Rmet_2213

CBW:	RR42_s2053

CCUP:

BKK81_21225

CUP:	BKK80_20655

CUU:	BKK79_25870

CPAU:

EHF44_25790(bluB)

BMA:

BMA2051

BMV:	BMASAVP1_A0862

BMAL:

DM55_2403(bluB)

BMAE:

DM78_2620(bluB)

BMAQ:

DM76_2388(bluB)

BMAI:

DM57_840

BMAF:

DM51_1710(bluB)

BMAZ:

BM44_1298(bluB)

BMAB:

BM45_860(bluB)

BPS:

BPSL2735

BPM:	BURPS1710b_3222

BPL:	BURPS1106A_3208(bluB)

BPD:	BURPS668_3169(bluB)

BPR:	GBP346_A3349(bluB)

BPSE:

BDL_2711(bluB)

BPSM:

BBQ_576(bluB)

BPSU:

BBN_704(bluB)

BPSD:

BBX_1109(bluB)

BPZ:	BP1026B_I0580

BPQ:	BPC006_I3251

BPK:	BBK_2197(bluB)

BPSH:

DR55_1783(bluB)

BPSA:

BBU_2828(rfaE)

BPSO:

X996_1424(bluB)

BUT:	X994_3423(bluB)

BTE:

BTH_I1401

BTQ:	BTQ_2531(bluB)

BTJ:	BTJ_3163(bluB)

BTZ:	BTL_1094(bluB)

BTD:	BTI_869(bluB)

BTV:	BTHA_1186(bluB)

BTHE:

BTN_294(bluB)

BTHM:

BTRA_1302(bluB)

BTHA:

DR62_460

BTHL:

BG87_1291(bluB)

BOK:	DM82_2401(bluB)

BOC:	BG90_2332(bluB)

BUU:	WS70_13950

BSAV:

WS86_04585

BHG:	I6G56_16330(bluB)

BUD:	AQ610_04225

BVI:	Bcep1808_0761

BVE:	AK36_44(bluB)

BUR:	Bcep18194_A3917

BCM:	Bcenmc03_0794

BCH:	Bcen2424_0824

BCJ:

BCAL3180

BCEN:

DM39_635(bluB)

BCEW:

DM40_1490(bluB)

BCEO:

I35_0677

BAM:

Bamb_0704

BAC:	BamMC406_0721

BMJ:	BMULJ_00679

BMU:

Bmul_2559

BMK:	DM80_861(bluB)

BMUL:

NP80_840(bluB)

BCT:

GEM_2704

BCED:

DM42_1005(bluB)

BCEP:

APZ15_07760

BDL:	AK34_2348(bluB)

BPYR:

ABD05_09740

BCON:

NL30_11665

BUB:	BW23_912(bluB)

BDF:	WI26_03625

BLAT:

WK25_03835

BTEI:

WS51_14400

BSEM:

WJ12_03730

BPSL:

WS57_21530

BMEC:

WJ16_03765

BSTG:

WT74_04030

BSTL:

BBJ41_08055

BANN:

JFN94_03885(bluB)

BARI:

NLX30_04040(bluB)

BAEN:

L3V59_04030(bluB)

BGL:	bglu_1g06950

BGU:	KS03_1624(bluB)

BUG:	BC1001_5801

BGF:	BC1003_5838

BGD:	bgla_1g07490

BGO:	BM43_2137(bluB)

BUK:

MYA_0715

BUL:	BW21_964(bluB)

BUQ:	AC233_33240

BGP:	BGL_1c06890(bluB)

BPLA:

bpln_1g06790

BUM:	AXG89_15870

BUI:	AX768_25655

BURK:

DM992_17480(bluB)

BXE:

Bxe_B1657

BXB:	DR64_6965(bluB)

BPH:

Bphy_3158

BGE:	BC1002_3795

BPX:	BUPH_05995

BPY:	Bphyt_4995

BUZ:	AYM40_25480

BFN:	OI25_4089(bluB)

BCAI:

K788_0002790

PSPW:

BJG93_27195(bluB)

PARA:

BTO02_29960

PARB:

CJU94_21265(bluB)

PHS:	C2L64_26605(bluB)

PTER:

C2L65_21780(bluB)

PGP:	CUJ91_24280(bluB)

PCJ:	CUJ87_20080(bluB)

PTS:	CUJ90_32085(bluB)

PCAF:

DSC91_001579

PMEG:

FNZ07_10820(bluB)

PTRO:

G5S35_18565(bluB)

PGIS:

I6I06_21750(bluB)

PACP:

FAZ97_16395(bluB)

PACS:

FAZ98_20950(bluB)

PEW:	KZJ38_31215(bluB)

PDIO:

PDMSB3_1431.1(bluB)

PBRY:

NDK50_29635(bluB)

PSAA:

QEN71_08685(bluB)

PKF:	RW095_08740(bluB)

PBON:

QS306_08320(bluB)

PPAI:

E1956_22570(bluB)

PVE:	UC34_18630

PFG:	AB870_05640

PLG:	NCTC10937_04026(drgA)

LMIR:

NCTC12852_01583(nox)

CABA:

SBC2_19430(bluB)

TVL:	FAZ95_24480(bluB)

TCAR:

U0034_26140(bluB)

RFR:

Rfer_2617

RAC:	RA876_06595

RHF:	EUB48_03070(bluB)

POL:

Bpro_2763

PNA:

Pnap_2149

POS:	DT070_18890(bluB)

POO:	F7R28_11685(bluB)

PVAC:

HC248_02569(bluB)

AJS:

Ajs_3177

ACID:

CBP33_07740 CBP33_18820

ACIP:

CBP36_08310 CBP36_19120

ACIN:

CBP34_07640

ACIS:

CBP35_10620 CBP35_19070

ACIO:

EAG14_08065(bluB)

ARAD:

KI609_14835(bluB)

ATEM:

PQV96_10500(bluB)

AAV:

Aave_1544

AAA:

Acav_1584

AMON:

H9L24_00845(bluB)

DAC:

Daci_2803

DEL:	DelCs14_3956

DTS:	BI380_09680

DHK:	BO996_12930

DLA:	I6G47_10220(bluB)

VAP:	Vapar_2554

VPE:	Varpa_3372

VBO:	CKY39_15830(bluB)

VAM:	C4F17_06880(bluB)

CTT:	CtCNB1_1849

CTES:

O987_11520

CKE:	B5M06_11790

CSER:

CCO03_13215

CAQT:

KAQ61_10230(bluB)

CODO:

LAD35_15490(bluB)

CTEZ:

CT3_29670

AANT:

HUK68_12180(bluB)

CRJ:	QMY55_10010(bluB)

OTD:	J1M35_08180(bluB)

DPY:	BA022_01080

DIH:	G7047_15400(bluB)

DAER:

H9K75_06245(bluB)

DRG:	H9K76_09435(bluB)

DIA:	Dtpsy_2528

CBAB:

SMCB_0328

MPT:	Mpe_B0452(cysG) Mpe_B0487(cysG)

RGE:

RGE_38910

RBN:	RBXJA2T_10966

ROI:	N4261_21040(bluB)

KIA:	G8A07_22645(bluB)

PAQA:

K9V56_018665(bluB)

HAR:

HEAR0425

MMS:

mma_2554

JAB:	VN23_17035

HSE:	Hsero_2645(nfnB)

HSZ:	ACP92_13245

HHT:	F506_13785

HRB:	Hrubri_2734(nfnB)

HEE:	hmeg3_12380(bluB)

HHF:	E2K99_14100(bluB)

HFR:	G5S34_14080(bluB)

MNR:	ACZ75_15335

MASS:

CR152_18195(bluB)

MASY:

DPH57_07805(bluB)

MANC:

IV454_30195(bluB)

MFY:	HH212_20270(bluB)

MALI:

EYF70_18620(bluB)

MUM:	FCL38_30330(bluB)

MFLA:

GO485_03375(bluB)

MPLI:

E1742_01310(bluB)

TCT:	PX653_08685(bluB)

DUG:	HH213_14780(bluB)

DZO:	SR858_23920(bluB)

RUG:	QC826_25330(bluB)

EHB:	E7V67_011765(bluB)

UPI:	EJG51_004275(bluB)

GLC:	JQN73_08110(bluB)

ACTB:

RHM62_08850(bluB)

XYK:	GT347_08685(bluB)

ETB:	N7L95_04065(bluB)

NII:	Nit79A3_2757

NCO:	AAW31_04095

DOE:	DENOEST_2511(bluB)

RBU:	PG1C_08110

TBD:

Tbd_2717

MFA:

Mfla_0115

MMB:

Mmol_0273

MEH:

M301_0171

MEI:	Msip34_0147

MEP:

MPQ_0158

MEU:	ACJ67_01710

FAM:	OYT1_ch1292

FKU:	FGKAn22_21320

SULF:

CAP31_14150

SPLB:

SFPGR_26500

DSU:

Dsui_0051

ARES:

IWH25_00295(bluB)

AIQ:	Azoinq_03840(bluB)

OTR:	OTERR_26010(bluB)

EBA:

ebA4029

ABRE:

pbN1_24710(bluB)

APET:

ToN1_35000(bluB)

RBH:	B4966_13360

DAR:

Daro_0141

DEY:	HYN24_00735(bluB)

DDEN:

KI615_00670(bluB)

DECH:

GBK02_02430(bluB)

QAU:	KI612_00610(bluB)

FLE:	KI610_00765(bluB)

AZO:

azo3524

AOA:

dqs_3667

AZA:	AZKH_0971(bluB)

AZI:	AzCIB_0846

AZD:	CDA09_05135(bluB)

AZR:	CJ010_21345(bluB)

TMZ:	Tmz1t_1140

THU:	AC731_018905

THAU:

C4PIVTH_0423(bluB)

TCL:

Tchl_0969

TAK:	Tharo_1007

AZQ:	G3580_05625(bluB)

ACOM:

CEW83_12075(bluB)

ZPA:	C3497_12735(bluB)

FPHO:

SHINM1_019340

FMY:	HO273_08710(bluB)

APP:	CAP2UW1_3912

MLO:

mll7468

MCI:	Mesci_5041

MOP:	Mesop_5628

MAM:	Mesau_05126

MAMO:

A6B35_13695

MESW:

A9K65_027695

MESM:

EJ066_19330(bluB)

MESP:

C1M53_01545(bluB)

MHUA:

MCHK_10520(bluB)

MJR:	EB229_28810(bluB)

MERD:

EB233_25160(bluB)

MOH:	IHQ72_25600(bluB)

MMEI:

LRP31_25855(bluB)

MESO:

BSQ44_15485

HOE:	IMCC20628_01361

AAK:	AA2016_2022

AMIH:

CO731_02143

AMIS:

Amn_43100

ANJ:	AMD1_2023(bluB)

PHT:	BLM14_04690

PHYL:

HB779_18605(bluB)

NRH:	T8J41_13475(bluB)

ORM:	HTY61_12580(bluB)

RBS:	RHODOSMS8_03440

SME:	SMc00166(bluB)

SMK:	Sinme_1747

SMQ:	SinmeB_1591

SMX:	SM11_chr1558(bluB)

SMI:	BN406_01574

SMEG:

C770_GR4Chr1896

SMEL:

SM2011_c00166(bluB)

SMER:

DU99_10045

SMD:

Smed_1562

RHI:	NGR_c16920(bluB)

SFH:	SFHH103_01574

SFD:	USDA257_c41170(bluB)

SIX:	BSY16_896(bluB)

SAME:

SAMCFNEI73_Ch2071(bluB)

SINO:

SS05631_c18510

ESJ:	SJ05684_c17480

EAK:	EKH55_1683

EMX:	FKV68_10605(bluB)

ENU:	PYH37_004223(bluB)

EGI:	PZN02_003263(bluB)

SKM:	PZL22_002097(bluB)

STEG:

QA637_07800(bluB)

EAH:	FA04_08000

ECAA:

J3R84_08095(bluB)

ENP:	JVX98_11790(bluB)

ATU:

Atu1654

ATA:	AWN88_13250

AGR:	AGROH133_06517

ATF:	Ach5_15820

AGC:	BSY240_349(bluB)

AGT:	EYD00_06315(bluB)

ALF:	CFBP5473_08565(bluB)

ARUI:

G6M88_01215(bluB)

AVQ:	HRR99_08145(bluB)

AVV:	RvVAT039_31310(bluB)

AVF:	RvVAR031_18280(bluB)

ASAL:

CFBP5507_06925(bluB)

RIR:	BN877_I1614(bluB)

RPUS:

CFBP5875_06860(bluB)

ACUC:

KZ699_06705(bluB)

ALEG:

CFBP4996_06620(bluB)

AVI:

Avi_2042

RET:	RHE_CH02368

REC:	RHECIAT_CH0002455

REL:	REMIM1_CH02380(bluB)

REP:	IE4803_CH02402(bluB)

REI:	IE4771_CH02490(bluB)

RLE:

RL2681

RLT:	Rleg2_1996

RLG:

Rleg_2211

RLB:	RLEG3_21715

RLU:	RLEG12_21410

RTR:	RTCIAT899_CH12935(bluB)

RHL:	LPU83_2251(bluB)

RGA:	RGR602_CH02141(bluB)

RHN:	AMJ98_CH02418(bluB)

RPHA:

AMC79_CH02487(bluB)

RHX:	AMK02_CH02433(bluB)

RHV:	BA939_02885

RHK:	Kim5_CH02485(bluB)

REZ:	AMJ99_CH02496(bluB)

RJG:	CCGE525_14150(bluB)

RHR:	CKA34_15820(bluB)

RGR:	FZ934_06825(bluB)

RAD:	CO657_10025(bluB)

RII:	FFM53_000155(bluB)

RHID:

FFM81_009510(bluB)

RBQ:	J2J99_12295(bluB)

RLN:	J0663_21365(bluB)

RBAN:

J2J98_11845(bluB)

RRG:	J3P73_13645(bluB)

RLS:	HB780_19320(bluB)

RROS:

D4A92_18545(bluB)

RAW:	NE851_22310(bluB)

RSUL:

N2599_07485(bluB)

RLW:	RlegWSM1455_11145(bluB)

RRHO:

PR018_07650(bluB)

RTU:	PR017_07830(bluB)

RCT:	PYR68_10120(bluB)

ARA:

Arad_3252

ARO:	B0909_04760(bluB)

RBW:	RLCC275e_11320(bluB)

RIF:	U5G49_002229(bluB)

NGL:	RG1141_CH16580

NGG:	RG540_CH17000

NEN:	NCHU2750_17230(bluB)

NPM:	QEO92_09265(bluB)

SHZ:

shn_09920

SOJ:	K6301_08005(bluB)

SSUM:

Q9314_18655(bluB)

PDES:

FE840_014880(bluB)

BME:

BMEII0246

BMEL:

DK63_2996(bluB)

BMI:	BMEA_B1040(bluB)

BMZ:	BM28_B1030

BMG:	BM590_B1028

BMW:	BMNI_II0996

BMEE:

DK62_2402(bluB)

BMF:

BAB2_1015

BMB:	BruAb2_0994

BMC:	BAbS19_II09410

BAA:	BAA13334_II01795

BABO:

DK55_2957(bluB)

BABR:

DO74_2595(bluB)

BABT:

DK49_3055(bluB)

BABB:

DK48_2839(bluB)

BABU:

DK53_2187(bluB)

BABS:

DK51_2767(bluB)

BABC:

DO78_2874(bluB)

BMS:

BRA1054

BSI:	BS1330_II1046

BSF:	BSS2_II1002

BSUI:

BSSP1_II1009

BSUP:

BSPT1_II1006

BSUV:

BSPT2_II1008

BSUC:

BSSP2_II1017

BMT:	BSUIS_B1050(bluB)

BSZ:	DK67_3001(bluB)

BSV:	BSVBI22_B1045

BSW:	IY71_16260

BSG:	IY72_16205

BOV:

BOV_A0993

BCS:	BCAN_B1076(bluB)

BSK:	BCA52141_II1489

BOL:	BCOUA_II1054

BCAR:

DK60_2738(bluB)

BCAS:

DA85_15545

BMR:	BMI_II1055

BPP:	BPI_II1111

BPV:	DK65_2602(bluB)

BCET:

V910_200239

BCEE:

V568_200270

BVL:	BF3285c2_0606

BRU:	BFS01_15150

BRJ:	BKD03_00105

OIN:	IAR37_12780(bluB)

BIO:	BR141012304_20838

OAN:

Oant_1328

OAH:	DR92_891(bluB)

OPS:	A8A54_00955

BPSN:

NIK97_06460(bluB)

OCH:	CES85_0268(bluB)

OCR:	HGK82_09405(bluB)

OCL:	GTN27_09715(bluB)

BJA:	bll3254(bll3254)

BJU:	BJ6T_64960

BJP:	RN69_31490

BRA:

BRADO4896

BBT:

BBta_3155

BRS:

S23_47500

AOL:	S58_27940(BluB)

BRC:	BCCGELA001_14645

BRAD:

BF49_1444

BIC:	LMTR13_27180

BRO:	BRAD285_2340(bluB)

BRK:	CWS35_19560(bluB) CWS35_24770

BOT:	CIT37_37290(bluB)

BRQ:	CIT40_10750(bluB)

BGQ:	X265_24850(bluB)

BGZ:	XH91_22890(bluB)

BSYM:

CIT39_09735(bluB)

BBET:

F8237_03880(bluB)

BARH:

WN72_17780(bluB)

BVZ:	BRAD3257_5446

BEL:	BE61_67660

BDG:	LPJ38_19085(bluB)

BSEP:

HAP48_0032315(bluB)

BQB:	J4P68_0033585(bluB)

BBAN:

J4G43_018795(bluB)

BCAN:

BcanWSM471_15495(bluB)

BAUT:

QA635_27100(bluB)

BBRA:

QA636_29050(bluB)

BGK:	IC762_13495(bluB)

BCOU:

IC761_23290(bluB)

BPAH:

QA639_16880(bluB)

BXN:	I3J27_12685(bluB)

BROS:

QUH67_09160(bluB)

BRAZ:

LRP30_14415(bluB)

RPA:	TX73_003680(bluB)

RPB:

RPB_0743

RPC:

RPC_3749

RPD:

RPD_0641

RPE:

RPE_2232

RPT:

Rpal_0782

RPX:	Rpdx1_0763

RBK:	E0H22_16585(bluB)

TRB:	HB776_11700(bluB)

TALZ:

RPMA_17430(bluB)

BOP:	AXW83_22035

BOS:	BSY19_867(bluB)

BVV:	BHK69_09235

BOI:	BLM15_18825

BOF:	FQV39_16550(bluB)

BVES:

QO058_18350(bluB)

BAPI:

BBC0122_002410

BAPA:

BBC0178_002410

XAU:

Xaut_2810

XDI:	EZH22_10855(bluB)

AZC:

AZC_4661

STAR:

G3545_08980(bluB)

LNE:	FZC33_27245(bluB)

SNO:

Snov_0877

ANC:	GBB76_01135(bluB)

APRA:

G3A50_03485(bluB)

APOL:

K9D25_19585(bluB)

MEA:	Mex_1p1981

MDI:

METDI2769

MEX:

Mext_2003

MCH:	Mchl_2280 Mchl_5732

MPO:

Mpop_1959

MZA:	B2G69_17475

MRD:	Mrad2831_1022

MET:

M446_3671

MNO:

Mnod_4520

MOR:	MOC_1239(bliB)

META:

Y590_09565

MAQU:

Maq22A_c24535(nfnB)

MPHY:

MCBMB27_00616

MEE:	DA075_24195(bluB)

METD:

C0214_11425(bluB)

METX:

A3862_25470

METS:

DK389_19950(bluB)

METI:

DK427_14150(bluB)

MMES:

MMSR116_26340(bluB)

MTEA:

DK419_22945(bluB)

MIND:

mvi_59650

MOG:	MMB17_03430(bluB)

MTAD:

M6G65_04095(bluB)

MLD:	U0023_25625(bluB) U0023_28880(bluB)

BID:

Bind_0168

MSL:

Msil_1629

MTUN:

MTUNDRAET4_3499

MLG:	CWB41_07395(bluB)

MEDK:

QEV83_02800(bluB)

BBAR:

RHAL1_01665

CHEL:

AL346_09070

CDQ:	BOQ54_02155

HDT:	HYPDE_34838

HMC:	HYPMC_2288

HNI:	W911_13010

RVA:

Rvan_1099

RLAC:

QMO75_16085(bluB)

FIL:	BN1229_v1_1057(bluB)

FIY:	BN1229_v1_1059(bluB)

RHZ:	RHPLAN_24040

MCG:

GL4_2686

METG:

HT051_06015(bluB)

DEI:	C4375_11590(bluB)

DSAL:

K1X15_07310(bluB)

DNP:	N8A98_04085(bluB)

BVR:

BVIR_899

BLAG:

BLTE_26230

MSC:

BN69_2844

MBRY:

B1812_02980

MROS:

EHO51_02065(bluB)

MHEY:

H2LOC_002235(bluB)

MPAR:

F7D14_03000(bluB)

MIWA:

SS37A_04680(bluB)

MTW:	CQW49_01800(bluB)

MECQ:

MSC49_19340

CMET:

K6K41_02475(bluB)

HDI:	HDIA_2853(nox)

AUA:	M673_15105

AUZ:	Sa4125_04160(bluB)

AUB:	LXB15_04760(bluB)

JIE:	OH818_10430(bluB)

BRN:	D1F64_17390(bluB)

NOH:	G5V57_29260(bluB)

PSF:	PSE_4445(blub)

PPHR:

APZ00_13400

LAP:	ACP90_07255

LABR:

CHH27_12970(bluB)

LABP:

FJ695_11505(bluB)

LABT:

FIU93_12910

LAGG:

B0E33_19320

SIW:	GH266_07600(bluB)

PSTG:

E8M01_25250(bluB)

LIZ:	LGH83_07435(bluB)

SIL:	SPO3254(bluB)

SIT:	TM1040_2608

RUA:	D1823_10830(bluB)

RUT:	FIU92_02435

RCON:

K3740_03775(bluB)

RDE:	RD1_3815(bluB)

RLI:	RLO149_c006290(bluB)

DSH:	Dshi_0347(bluB)

PGA:	PGA1_c00550

PGL:	PGA2_c30310

PGD:

Gal_00189

PHP:	PhaeoP97_00284

PPIC:

PhaeoP14_02998

PHQ:	D1820_10810(bluB)

OAT:	OAN307_c11000(bluB1) OAN307_c37400(bluB2)

OAR:	OA238_c14410(bluB)

OTM:

OSB_01690

LMD:	METH_00500

LEJ:	ETW24_00495(bluB)

LAQU:

R2C4_16585(bluB)

LCAE:

K3721_00655(bluB)

CID:

P73_0743

CEH:	CEW89_16045(bluB)

MALG:

MALG_01223

PABY:

Ga0080574_TMP3269

SUAM:

BOO69_01455

SULZ:

C1J03_02630(bluB)

SULI:

C1J05_01840(bluB)

SULD:

B5M07_15185

SPOT:

G6548_05290(bluB)

SMED:

JNX03_11275(bluB)

SINL:

DSM14862_02978

SFAV:

PL335_14240(bluB)

SUAL:

KDD17_12705(bluB)

SDUB:

R1T39_09060(bluB)

TOM:	BWR18_13980

RMM:	ROSMUCSMR3_02323

ROK:	RAK1035_0860

RID:	RIdsm_04823(nox_2)

ROM:	EI983_15655(bluB)

ROH:	FIU89_17280(bluB)

RPEL:

N7U68_09555(bluB)

AHT:	ANTHELSMS3_03563(bluB)

SAGU:

CDO87_04175(bluB)

THAA:

CFI11_01680(bluB)

MALU:

KU6B_24700

HAT:	RC74_03845

PALX:

GQA70_05725(bluB)

LSAL:

KBK07_02530(bluB)

MARU:

FIU81_15375

RSP:

RSP_3218

RSH:	Rsph17029_3956

RSQ:	Rsph17025_3598

RSK:	RSKD131_3398

CAZT:

LV780_17765(bluB)

RCP:	RCAP_rcc02052(bluB)

RHP:	LPB142_02350

RBL:	B6K69_04465

PDE:

Pden_2527

PAMI:

JCM7686_1428

PZH:	CX676_12530(bluB)

PARO:

CUV01_05585(bluB)

PAMN:

JCM7685_0443(bluB)

PARR:

EOJ32_03260(bluB)

PKD:	F8A10_01405(bluB)

PPAN:

ESD82_11615(bluB)

PLIA:

E4191_01230(bluB)

PMAU:

CP157_02935(bluB)

PSEW:

JHW44_15990(bluB)

PSAP:

JHX88_00455(bluB)

PFIS:

JHX87_12750(bluB)

PALP:

JHW40_15690(bluB)

PVER:

E3U25_21470(bluB)

PFEO:

E3U26_09740(bluB)

RSU:	NHU_03432(bluB)

RHM:	B5V46_03740

RHC:

RGUI_2964

RMB:	K529_012535

TSCO:

R1T40_18825(bluB)

DON:	BSK21_02535

RBZ:	B9057_11020

LVS:	LOKVESSMR4R_00075(bluB)

RBG:	BG454_16785(bluB)

GEH:	HYN69_19310(bluB) HYN69_20120(bluB)

GFU:	KM031_06480(bluB)

TAW:	EI545_12905(bluB)

SEDI:

EBB79_00800(bluB)

PPSO:

QPJ95_06285(bluB)

PSEB:

EOK75_13005(bluB)

PPRU:

FDP22_21355(bluB)

PAED:

G5B38_14380(bluB)

MON:	G8E03_05400(bluB)

PAMO:

BAR1_16135(bluB)

POZ:	I0K15_13885(bluB)

PSHQ:

F3W81_03810(bluB)

PGV:	SL003B_1177

CACT:

HZ995_08540(bluB)

NSM:	JO391_13630(bluB)

ACRO:

K3J57_02030(bluB) K3J57_03155(bluB)

SINR:

O5O51_07210(bluB)

AMYL:

QBD29_13900(bluB)

PBAE:

P8S53_11855(bluB)

LVR:	T8T21_09800(bluB)

FAQ:	G5B39_09260(bluB)

NAR:

Saro_0330

NPP:	PP1Y_AT19897

NPN:	JI59_17255

NRE:	BES08_06830

NOV:	TQ38_022005(bluB)

NOR:	FA702_01460(bluB)

NHUM:

PQ457_18135(bluB)

SPHP:

LH20_21890

SPHM:

G432_07700

STAX:

MC45_16140

SPAN:

AWL63_14885

SPLK:

AV944_15005

SPHA:

D3Y57_03040(bluB)

SPAU:

DRN02_008555(bluB)

SECH:

B18_18110

SBIN:

SBA_ch1_32960

SAER:

NEF64_15360(bluB)

SMOR:

LHA26_14895(bluB)

SHAN:

PPZ50_08525(bluB)

SSAG:

KV697_06570(bluB)

SJP:	SJA_C2-03090(bluB)

SINB:

SIDU_11840

SCH:	Sphch_3766

SYB:	TZ53_06710

SBD:	ATN00_04725

SPMI:

K663_18386

SPHB:

EP837_03436(bluB)

SPHT:

K426_22454

SYA:	A6768_22445(bluB)

SBAR:

H5V43_18260(bluB)

SPPH:

KFK14_09750(bluB)

BLAS:

BSY18_2561(bluB)

BFW:	B5J99_03765

PARJ:

J4G78_04065(bluB)

POQ:	KZX46_05935(bluB)

PMEA:

KTC28_05550(bluB)

NTD:	EGO55_18855(bluB)

GOH:

B932_2921

GTI:	FXF46_12940(bluB)

GFA:	MKW11_13465(bluB)

GBE:	GbCGDNIH1_1100

GBH:	GbCGDNIH2_1100

GBC:	GbCGDNIH3_1100

GBS:	GbCGDNIH4_1100

GDI:

GDI0656

GDJ:

Gdia_1350

GXY:

GLX_15140

GXL:

H845_259

KNA:	B0W47_10740

KEU:	S101446_02107(bluB)

KSC:	CD178_01279

KRE:	GWK63_13710(bluB)

KOI:	LV478_04780(bluB)

APT:	APA01_22470

APW:	APA42C_22470

APF:	APA03_22470

APU:	APA07_22470

APG:	APA12_22470

APQ:	APA22_22470

APX:	APA26_22470

APZ:	APA32_22470

APK:	APA386B_1106

ASZ:

ASN_886

ASV:	WG31_11375

APER:

A0U91_10690

APOM:

CPF11_09385(bluB)

ATO:	CIW82_07665(bluB)

AASC:

A4S02_00520

ACET:

DS739_11025(bluB)

AOT:	AcetOri_orf03973

AOY:	EOV40_010670(bluB)

ACEK:

FLP30_06815(bluB)

ABG:	Asbog_00257

KBA:	A0U89_06165

RGI:	RGI145_12710

ROS:	CTJ15_04825(bluB)

RMUC:

FOB66_14380(bluB)

RMT:	IAI58_10265(bluB)

RCV:	PFY06_17265(bluB)

COQ:	D9V35_02740(bluB)

COMM:

GN303_02610(bluB)

SSAM:

E3D00_09320(bluB)

EBLA:

JGUZn3_06590

LCK:	HN018_17760(bluB)

KHA:	IFJ82_02480(bluB)

RAP:	RHOA_3183(bluB)

ACIM:

GT370_20575(bluB)

KDP:	N5W20_06345(bluB)

NGU:	QN315_14990(bluB)

AZL:	AZL_d03400

ALI:	AZOLI_p40236(bluB)

ABS:	AZOBR_p140044(bluB)

ABQ:	ABAZ39_19955

ABF:	AMK58_14885

ATI:	AL072_25385

AZT:	TSH58p_24095(bluB)

AZM:	DM194_24320(bluB)

AZZ:	DEW08_00500(bluB)

AOZ:	HUE56_04845(bluB)

AARE:

D3093_22535(bluB)

AZS:	E6C72_27085(bluB)

NAO:	Y958_27810(bluB)

SKT:	IGS68_15035(bluB)

SMUC:

JL100_011105(bluB)

SROE:

JL101_014560(bluB)

RRU:

Rru_A3536

RRF:

F11_18105

RCE:	RC1_3717(bluB)

RPM:	RSPPHO_01505

MGY:	MGMSRv2__2101

MGRY:

MSR1_20970(bluB)

MAGX:

XM1_1861(bluB)

MAGN:

WV31_17055

FER:	FNB15_02575(bluB)

DEX:	HWD60_13335(bluB)

DVN:	HQ394_16925(bluB)

MAG:

amb1227

HTQ:	FRZ44_52940

HADH:

FRZ61_51430

TXI:

TH3_17990

THAC:

CSC3H3_17110(bluB)

TII:	DY252_03810(bluB)

THAI:

IT893_16995(bluB)

TLU:	R1T41_05535(bluB)

TTB:	MACH01_33450

MAGQ:

MGMAQ_2057

VSU:	P3M64_12070(bluB)

NACI:

NUH88_03590(bluB)

TMO:

TMO_c0843

MGM:

Mmc1_1683

ECOG:

FIV45_04675(bluB)

SNEA:

NBZ79_18980(bluB)

KOZ:	KFF44_03300(bluB)

HTL:

HPTL_1957

SUA:

Saut_0152

SPAL:

FM071_05130(bluB)

SMAX:

FJR03_00445(bluB)

SKU:	Sulku_0029

SBA:	Sulba_2132

ANT:	Arnit_1842

AELL:

AELL_0098(bluB)

AAQI:

AAQM_0045(bluB)

ASUI:

ASUIS_0093(bluB)

ACLO:

ACLO_0044(bluB)

AVP:	AVENP_0115(bluB)

ADZ:	ADFLV_0129(bluB)

ARC:

ABLL_0134

PACO:

AACT_0122(bluB)

AROS:

NJU99_00455(bluB)

ALK:	ALEK_0092 ALEK_0331(bluB)

ALP:	LPB137_00310

AHS:	AHALO_0060(bluB)

AMYT:

AMYT_0065(bluB)

AMAR:

AMRN_0058(bluB)

ACAA:

ACAN_0060(bluB)

AMOL:

AMOL_0056(bluB)

APAI:

APAC_0069(bluB)

HBV:	ABIV_1418(bluB)

HEBR:

AEBR_1665(bluB)

DDU:

GF1_30330

DWD:	DSCW_09240

AVM:	JQX13_42310(bluB)

CFUS:

CYFUS_006244

SCU:	SCE1572_32725

BWH:	A9C19_10130

BACI:

B1NLA3E_15285

BACO:

OXB_2234

BMQ:	BMQ_0968(bluB)

BMD:	BMD_0969(bluB)

BMH:	BMWSH_4275

BMEG:

BG04_3258(bluB)

BEO:

BEH_16050

PARH:

I5S86_07225(bluB)

PKS:	IE339_08670(bluB)

BKW:	BkAM31D_09100(bluB)

BPF:	BpOF4_04650

GTK:	GT3570_02370

ASED:

IRT44_10570(bluB)

LSP:

Bsph_2918

FEC:	QNH15_04725(bluB)

BSJ:	UP17_02580

PBUT:

DTO10_14460(bluB)

PASA:

BAOM_2057(bluB)

PFRI:

L8956_03045(bluB)

NCM:	QNK12_17950(bluB)

MSEM:

GMB29_07095(bluB)

MDG:	K8L98_13655(bluB)

MLIT:

KDJ21_019465(bluB)

DOM:	RRU94_01550(bluB)

AHAL:

FTX54_002395(bluB)

BBE:	BBR47_15030

BLR:	BRLA_c035940

BFM:	BP422_02710

BAGR:

BA6348_21240(bluB)

BRW:	GOP56_10060(bluB)

BCHS:

JNE38_08095(bluB)

BPAB:

PSE45_07515(bluB)

BAYD:

BSPP4475_14955(bluB)

PMS:	KNP414_07714

PMQ:	PM3016_7242

PMW:

B2K_36545

PNP:	IJ22_10920

PKB:	B4V02_20785

PAIH:

ASL14_07395

PCHI:

PC41400_07790(bluB)

PTHI:

NDS46_24785(bluB)

PDY:	QJQ58_27325(bluB)

PKP:	SK3146_04078(bluB)

ANX:	ACH33_02955

ASOC:

CB4_00860(bluB)

ATHE:

K3F53_15980(bluB)

AACO:

K1I37_13600(bluB)

ADAU:

NZD86_09630(bluB)

AFAS:

NZD89_11185(bluB)

ACYC:

JI721_10795(bluB)

BTS:

Btus_0240

KYR:	CVV65_04120(bluB)

TUM:	CBW65_02925

TAB:	CIG75_03810(bluB)

EFF:	skT53_30580

SPOR:

SporoP33_00575

SPOP:

SporoP37_00980

SURE:

SporoP32a_00720

SPOS:

DV702_11295(bluB)

LFB:	C1X05_02805(bluB)

TVU:	AB849_002500(bluB)

PABS:

JIR001_06230(bluB)

JPO:	G7058_04730

DAI:	Desaci_1485

EUZ:	DVS28_a2983

MTU:

Rv0306

MTV:

RVBD_0306

MTC:	MT0319(bluB)

MRA:

MRA_0315

MTF:	TBFG_10311

MTB:	TBMG_00310

MTK:	TBSG_00313

MTZ:	TBXG_000309

MTG:	MRGA327_01970

MTI:	MRGA423_01970

MTE:	CCDC5079_0284

MTUR:

CFBS_0323

MTL:	CCDC5180_0281

MTO:	MTCTRI2_0312

MTD:

UDA_0306

MTN:	ERDMAN_0340

MTJ:	J112_01665

MTUB:

MT7199_0312

MTUC:

J113_02240

MTUE:

J114_01665

MTX:	M943_01615

MTUL:

TBHG_00302

MTUT:

HKBT1_0323

MTUU:

HKBT2_0323

MTQ:	HKBS1_0323

MBO:	BQ2027_MB0314

MBB:

BCG_0346

MBT:

JTY_0316

MBM:	BCGMEX_0316

MBK:	K60_003270

MBX:

BCGT_0075

MAF:

MAF_03080

MMIC:

RN08_0350

MCE:	MCAN_03081

MCQ:	BN44_10343

MCV:	BN43_10338

MCX:	BN42_20035

MCZ:	BN45_10336

MORY:

MO_000326(bluB)

MPA:

MAP_3792c

MAO:

MAP4_3902

MAVI:

RC58_19380

MAVU:

RE97_19430

MAV:	MAV_4857(bluB)

MIT:

OCO_47660

MIA:

OCU_47580

MID:

MIP_07209

MYO:

OEM_47810

MCHI:

AN480_24765

MIR:

OCQ_48670

MMAL:

CKJ54_22675(bluB)

MMAN:

MMAN_35850

MSA:	Mycsm_05854

MUL:

MUL_1218

MMI:

MMAR_0555

MMAE:

MMARE11_05120

MLI:	MULP_00559

MPSE:

MPSD_06720

MSHO:

MSHO_19650

MMC:

Mmcs_4721

MKM:

Mkms_4807

MJL:

Mjls_5106

MMM:

W7S_23895

MKN:	MKAN_17050

MYV:	G155_26550

MYE:	AB431_08640

MHAD:

B586_00820

MDX:	BTO20_04320

MSHG:

MSG_00497(bluB)

MFJ:	MFLOJ_30080

MSTO:

MSTO_33960(bluB)

MSIM:

MSIM_19740

MSAK:

MSAS_39010

MKU:	I2456_03095(bluB)

MLW:	MJO58_02630(bluB)

MXE:	MYXE_45700

MNV:	MNVI_20540

MPAG:

C0J29_03090(bluB)

MNM:	MNVM_15180

MGOR:

H0P51_03095(bluB)

MCOO:

MCOO_36510

MBAI:

MB901379_00464

MSEO:

MSEO_44010

MHEK:

JMUB5695_04412(bluB)

MGAU:

MGALJ_38700

MLJ:	MLAC_38870

MBRD:

MBRA_11780

MMAM:

K3U93_02520(bluB)

MSPG:

F6B93_02175(bluB)

MOT:	LTS72_23145(bluB)

MPAA:

MKK62_22725(bluB)

MMEH:

M5I08_22965(bluB)

MKY:	IWGMT90018_05740

MADI:

A7U43_06540

MWU:	PT015_19840(bluB)

MSM:	MSMEG_6053(bluB)

MSG:	MSMEI_5893(bluB)

MSB:	LJ00_29930

MSN:	LI99_29935

MSH:	LI98_29940

MVA:

Mvan_0381

MGI:

Mflv_0353

MSP:	Mspyr1_04040

MCB:	Mycch_0306

MNE:	D174_24825

MYN:	MyAD_24360

MFT:	XA26_53750

MPHL:

MPHLCCUG_00478(bluB)

MVQ:

MYVA_0352

MLL:	B1R94_20635

MRH:	MycrhN_2231

MTHN:

4412656_04105(drgA_2)

MHAS:

MHAS_03791(bluB_2)

MDU:	MDUV_39870

MCHT:

MCHIJ_11870

MDR:	MDOR_32460(bluB)

MAUU:

NCTC10437_00337

MMAG:

MMAD_09640

MMOR:

MMOR_11630

MFX:	MFAL_30020(bluB)

MAIC:

MAIC_14610(bluB)

MIJ:	MINS_02920(bluB)

MALV:

MALV_42010(bluB)

MTY:	MTOK_21880(bluB)

MPSC:

MPSYJ_05740

MARZ:

MARA_47300(bluB)

MGAD:

MGAD_37820(bluB)

MHEV:

MHEL_38770

MSAR:

MSAR_02590(bluB)

MANY:

MANY_00290(bluB)

MAUB:

MAUB_23490(bluB)

MPOF:

MPOR_08770

MPHU:

MPHO_47040(bluB)

MMUC:

C1S78_023735(bluB)

MMAT:

MMAGJ_33570(bluB)

MBOK:

MBOE_05130(bluB)

MFG:	K6L26_05260(bluB)

MSEI:

MSEDJ_02680(bluB)

MFLV:

NCTC10271_00454

MCEE:

MCEL_37610(bluB)

MBRM:

L2Z93_000233(bluB)

MMON:

EWR22_25530(bluB)

MGO:	AFA91_10500 AFA91_20110

MHOL:

K3U96_03005(bluB)

MSEN:

K3U95_25610(bluB)

MPAE:

K0O64_08155(bluB)

MRF:	MJO55_01545(bluB)

MDF:	K0O62_26045(bluB)

MCRO:

MI149_09160(bluB)

MGRO:

FZ046_14350(bluB)

MKR:	MKOR_27880(bluB)

MPAK:

MIU77_17395(bluB)

MAB:

MAB_3351c

MMV:	MYCMA_1848

MABB:

MASS_3291

MABL:

MMASJCM_3350

MCHE:

BB28_16885

MIZ:	BAB75_17860

MSTE:

MSTE_03317

MSAO:

MYCSP_15295

MSAL:

DSM43276_03140(bluB_1)

MJD:	JDM601_0303

MTER:

4434518_00283(drgA)

MMIN:

MMIN_20150

MHIB:

MHIB_38080(bluB)

MHER:

K3U94_01750(bluB)

MVM:	MJO54_01520(bluB)

ASD:

AS9A_3944

CKP:	ckrop_1471

COA:	DR71_711(bluB)

CMV:	CMUST_11530

CLW:	CLAC_10360

CAQU:

CAQU_10690

CSPH:

CSPHI_10175

CXE:	FOB82_03715

CAMC:

I6I65_05765(bluB)

CFG:	CFREI_11750(bluB)

CCAW:

CCANI_11825(bluB)

CDUR:

CDUR_11520(bluB)

CHAN:

CHAN_11810(bluB)

NFA:

NFA_46050

NFR:	ERS450000_05323(nox_2)

NCY:	NOCYR_4329

NBR:	O3I_035045

NNO:	NONO_c63070

NSL:	BOX37_24565

NSR:	NS506_02094(bluB)

NOZ:	DMB37_13710(bluB)

NOD:	FOH10_03695(bluB)

NAH:	F5544_36950(bluB)

NAD:	NCTC11293_05908

NWL:	NWFMUON74_13610

NIE:	KV110_34080(bluB)

NTC:	KHQ06_12925(bluB)

NHU:	H0264_12380(bluB)

NYA:	LTV02_20560(bluB)

NGP:	LTT66_19875(bluB)

NSPU:

IFM12276_09560

NYU:	D7D52_00590(bluB)

RHA:	RHA1_ro06424

RER:

RER_23360

REY:

O5Y_10925

REB:	XU06_11145

RQI:	C1M55_12190(bluB)

ROP:

ROP_64780

ROA:	Pd630_LPD03090

RPY:	Y013_19835

RBY:	CEJ39_06250(bluB)

RHB:

NY08_4457

RAV:	AAT18_05055

RFA:	A3L23_02553(bluB_1)

RHS:	A3Q41_00810(bluB_1)

RHW:	BFN03_05010

RRZ:	CS378_20560(bluB)

RHU:	A3Q40_03153(bluB)

RHQ:	IM25_09580

RHOD:

AOT96_22405

RRT:	4535765_00760

RCR:	NCTC10994_01971

RTM:	G4H71_18425(bluB)

RKO:	JWS14_34870(bluB)

RGO:	KYT97_07190(bluB)

ROZ:	CBI38_18650

RPSK:

JWS13_09055(bluB)

RGOR:

NMQ04_03280(bluB)

RANT:

RHODO2019_10650(bluB)

REQ:

REQ_32250

PDEF:

P9209_12715(bluB)

WHR:	OG579_09575(bluB)

GPO:	GPOL_c29810(bluB)

GOR:

KTR9_2026

GOQ:	ACH46_10675

GTA:	BCM27_10890

GOC:	CXX93_12090(bluB)

GRU:	GCWB2_14845

GOM:	D7316_01112

GAV:	C5O27_13285(bluB)

GOD:	GKZ92_13660(bluB)

GJI:	H1R19_10085(bluB)

GOI:	LK459_18390(bluB)

GHN:	MVF96_10290(bluB)

GAMI:

IHQ52_17455(bluB)

GMG:	NWF22_23185(bluB)

GSI:	P5P27_10020(bluB)

TPR:

Tpau_0087

TSM:	ASU32_00990

TPUL:

TPB0596_01590

TSD:	MTP03_00730

DTM:	BJL86_3103

DIZ:	CT688_01000(bluB)

DPC:	A6048_01040

DLU:	A6035_16390

DKN:	NHB83_00905(bluB)

TOY:	FO059_17305(bluB)

TEH:	GKE56_07790(bluB)

PPC:	HMPREF9154_2365(bluB)

ARUB:

J5A65_04165(bluB)

TEZ:	BKM78_01665

TLA:	TLA_TLA_00339(bluB)

NCA:

Noca_3407

NDK:	I601_3845(bluB)

NARO:

CFH99_15715(bluB)

NPI:	G7071_10085(bluB)

NAQU:

ENKNEFLB_00275(bluB_1)

NRO:	K8W59_16030(bluB)

NPC:	KUV85_07245(bluB)

PSIM:

KR76_17070

AER:	AERYTH_08050

AMAZ:

LUW76_32115(bluB)

ACIR:

OG979_13160(bluB)

FRA:	Francci3_2878

FRE:	Franean1_7192

FAL:

FRAAL4424

FSY:	FsymDg_0790

FRI:	FraEuI1c_1386

SEN:

SACE_0750

SACG:

FDZ84_15400(bluB)

AMD:

AMED_7059

AMN:

RAM_36220

AMM:

AMES_6951

AMZ:

B737_6951

AOI:	AORI_4778(bluB)

AJA:	AJAP_15750

AMQ:	AMETH_5462

AMYC:

CU254_28560(bluB)

AORI:

SD37_18645

AACD:

LWP59_31855(bluB)

APRT:

MUY14_01250(bluB)

AROO:

NQK81_43020(bluB)

ATHM:

L1857_30290(bluB)

ARHD:

VSH64_19285 VSH64_24635(bluB)

PBRO:

HOP40_19140(bluB)

PPEL:

H6H00_17905(bluB)

APRE:

CNX65_02995(bluB)

AMI:

Amir_0603

SESP:

BN6_06460

SSYI:

EKG83_03175(bluB)

KAL:

KALB_710

KUT:	JJ691_53270 JJ691_71080

KPHY:

AOZ06_41350

LED:	BBK82_11005

ALO:

CRK56139

SACE:

GIY23_02910(bluB)

ACTU:

Actkin_04077

CROS:

N8J89_03245(bluB)

UME:	RM788_28605(bluB)

STP:	Strop_4448

SAQ:

Sare_4962

MICH:

FJK98_13025(bluB)

MCAB:

HXZ27_01050(bluB)

MSAG:

GCM10017556_28380

VER:	HUT12_13835(bluB)

MHAW:

RMN56_10410(bluB)

ASE:

ACPL_4734

AMS:	AMIS_42920

ACTN:

L083_1238

AFS:

AFR_28530

ACTS:

ACWT_4603

AIH:	Aiant_74920

ACTR:

Asp14428_02210

ACTL:

L3i22_070560

ASIC:

Q0Z83_062280(bluB)

AOU:	ACTOB_002883(bluB)

PSUU:

Psuf_061640

DVC:	Dvina_22380(bluB)

DFU:	Dfulv_23215(bluB)

DAUR:

Daura_13770(bluB)

DMAT:

Dmats_18015(bluB)

NHY:	JQS43_15980(bluB)

CCAZ:

COUCH_11790(bluB)

AEY:	CDG81_03400(bluB)

AFO:

Afer_0271

TER:

Tery_4461

FIS:	FIS3754_24110

DDR:	Deide_2p01660

DPD:	Deipe_1386

DAQU:

M8445_15565(bluB)

TTH:

TT_P0018

TTJ:	TTHB061(TTHB061)

TTS:	Ththe16_2310

TPAR:

AV541_10625

SACI:

Sinac_2349

LPRO:

PQO03_18930(bluB)

ACM:	AciX9_2619

GMA:	AciX8_3095

GRB:	GOB94_00270(bluB)

ABAS:

ACPOL_5147

CTM:	Cabther_B0726

CVL:	J8C06_12530(bluB)

CHLO:

J8C02_12580(bluB)

MSIL:

METEAL_00560

MSEA:

METESE_00470

MCOS:

GM418_17840

NKO:	Niako_0863

AUP:	AsAng_0019140

HNV:	DDQ68_09705(bluB)

FUA:	LVD17_09210(bluB)

ATK:	AUTU_33400

FCO:	FCOL_02425

FCV:	AWN65_05220

FOE:	JJC03_16025(bluB)

TDI:	AUW17_05090

TJE:	TJEJU_2902(bluB)

TOV:	PG911_07445(bluB)

TPAC:

PG913_05140(bluB)

TFI:	PJJ26_05420(bluB)

FOP:	FNB79_10720(bluB)

FEK:	C1H87_22350(bluB)

TAJ:	C1A40_12050(bluB)

AQB:	D1818_17245(bluB)

AQA:	D1815_13545(bluB)

AQD:	D1816_22885(bluB)

CTE:

CT0937

CPC:

Cpar_1182

CLZ:	BIU88_04940

CCH:

Cag_1013

CPH:	Cpha266_1116

CPB:	Cphamn1_1517

CLI:

Clim_1065

PLT:

Plut_1141

PPH:

Ppha_1263

PAA:

Paes_1270

PROS:

CHL67_05125(bluB)

CTS:

Ctha_2225

NDE:	NIDE2104(bluB) NIDE2667

NMV:	NITMOv2_1603 NITMOv2_1834

NKF:	Nkreftii_001751

NALL:

PP769_12130(bluB)

NNEO:

PQG83_02980(bluB)

LFC:

LFE_0654

LFI:	LFML04_1978

LFP:	Y981_10060

LEG:	ABH19_10435

NLI:	G3M70_14595(bluB)

NVA:	G3M78_09525(bluB)

MOX:

DAMO_2090

HHI:	HAH_1104(nfnB)

HHN:	HISP_05665

HAB:	SG26_13325

HTA:	BVU17_05395

HSIN:

KDQ40_07960(bluB)

HVO:	HVO_0641(bluB)

HME:	HFX_2169(nfnB)

HGI:	ABY42_03060

HALE:

G3A49_03280(bluB)

HLS:	KU306_07795(bluB)

HLN:	SVXHx_0600(blub)

HRE:	K6T36_15555(bluB)

HSAL:

JMJ58_01070(bluB)

NAT:

NJ7G_1056

NPE:	Natpe_1631

NVR:	FEJ81_08435(bluB)

NPL:	FGF80_03005(bluB)

NAY:	HYG81_01280(bluB)

HALY:

HYG82_04000(bluB)

HJT:	DVR14_17650(bluB) DVR14_21780(bluB)

HLO:	J0X27_03030(bluB)

HLR:	HALLA_14820

NAJ:	B1756_13280

NAG:	AArcMg_2113

NAN:	AArc1_1573

NARA:

QQ977_06230(bluB)

NBG:	DV706_12235(bluB)

NAS:	GCU68_16585(bluB)

HDA:	BB347_07340

FAC:	FACI_IFERC01G0489

FAI:	FAD_1404(bluB)

STO:

STK_06010

SOH:	D1869_02865(bluB)

SSO:

SSO2560

SOL:

Ssol_0371

SSOA:

SULA_0365(bluB)

SSOL:

SULB_0367(bluB)

SSOF:

SULC_0365(bluB)

SSHI:

J5U23_00925

SCAS:

SACC_22260

SAI:

Saci_0250

SACN:

SacN8_01220

SACR:

SacRon12I_01220

SACS:

SUSAZ_01270

SIS:	LS215_2909

SIA:	M1425_2744

SIM:	M1627_2797

SID:

M164_2727

SIY:	YG5714_2923

SIN:	YN1551_3111

SII:

LD85_3070

SIH:

SiH_2702

SIR:

SiRe_2639

SIC:

SiL_2588

SULE:

GFS03_01230(bluB)

SULO:

GFS33_06430(bluB)

SULL:

EWF20_04385(bluB)

MSE:

Msed_1226

MEMJ:

MJ1HA_1424

MCN:

Mcup_1028

MPRU:

DFR88_00225(bluB)

MJN:	MjAS7_2245

AHO:

Ahos_2079

AMAN:

B6F84_01685

ABRI:

DFR85_00545(bluB)

ASUL:

DFR86_01675(bluB)

AAMB:

D1866_05405(bluB)

ACIH:

HS5_08960

SAZO:

D1868_01125(bluB)

CSTY:

KN1_17300

STEP:

IC006_2634

SMET:

RQ359_001816(bluB)

TUZ:

TUZN_1096

NMR:

Nmar_1736

NIR:	NSED_09240

NKR:	NKOR_09225

NID:	NPIRD3C_0186(bluB)

NIN:	NADRNF5_0135(bluB)

NIW:	Nisw_05345(bluB)

NCL:	C5F47_08960(bluB)

NOX:	C5F49_08805(bluB)

NUE:	C5F50_12300(bluB)

NIP:	NsoK4_09700(bluB)

NZT:	NZOSNM25_000073

NCT:

NMSP_1655

NIC:	DSQ20_09845(bluB)

NGA:	Ngar_c24770

NVN:	NVIE_015450

NEV:

NTE_00833

TAA:	NMY3_02515(bluB_2)

NFN:	NFRAN_0098(bluB)

NCV:	NCAV_1669(bluB)

CSY:	CENSYa_1556

NBV:	T478_1447(bluB)

TAH:	SU86_006055

NIU:	DSQ19_00120(bluB)

NDV:	NDEV_2067(bluB)

» show all

Reference

1 [PMID:17301238]

Authors

Gray MJ, Escalante-Semerena JC

Title

Single-enzyme conversion of FMNH2 to 5,6-dimethylbenzimidazole, the lower ligand of B12.

Journal

Proc Natl Acad Sci U S A 104:2921-6 (2007)
DOI:10.1073/pnas.0609270104

Sequence

[rru:Rru_A3536]

Reference

2 [PMID:17377573]

Authors

Ealick SE, Begley TP

Title

Biochemistry: molecular cannibalism.

Journal

Nature 446:387-8 (2007)
DOI:10.1038/446387a

Reference

3 [PMID:17377583]

Authors

Taga ME, Larsen NA, Howard-Jones AR, Walsh CT, Walker GC

Title

BluB cannibalizes flavin to form the lower ligand of vitamin B12.

Journal

Nature 446:449-53 (2007)
DOI:10.1038/nature05611

Sequence

[sme:SMc00166]

Reference

4 [PMID:21344938]

Authors

Wang XL, Quan JM

Title

Intermediate-assisted multifunctional catalysis in the conversion of flavin to 5,6-dimethylbenzimidazole by BluB: a density functional theory study.

Journal

J Am Chem Soc 133:4079-91 (2011)
DOI:10.1021/ja1106207

Reference

5 [PMID:23457476]

Authors

Collins HF, Biedendieck R, Leech HK, Gray M, Escalante-Semerena JC, McLean KJ, Munro AW, Rigby SE, Warren MJ, Lawrence AD

Title

Bacillus megaterium has both a functional BluB protein required for DMB synthesis and a related flavoprotein that forms a stable radical species.

Journal

PLoS One 8:e55708 (2013)
DOI:10.1371/journal.pone.0055708

Other DBs

ExplorEnz - The Enzyme Database:

1.13.11.79

IUBMB Enzyme Nomenclature:

1.13.11.79

ExPASy - ENZYME nomenclature database:

1.13.11.79

BRENDA, the Enzyme Database:

1.13.11.79

DBGET integrated database retrieval system