KEGG   ENZYME: 1.13.11.82
Entry
EC 1.13.11.82               Enzyme                                 

Name
8'-apo-carotenoid 13,14-cleaving dioxygenase;
NACOX1 (gene name)
Class
Oxidoreductases;
Acting on single donors with incorporation of molecular oxygen (oxygenases);
With incorporation of two atoms of oxygen
Sysname
8'-apo-beta-carotenal:oxygen 13,14-dioxygenase (bond-cleaving)
Reaction(IUBMB)
8'-apo-beta-carotenal + O2 = 13-apo-beta-carotenone + 2,6-dimethyldeca-2,4,6,8-tetraenedial [RN:R11052]
Reaction(KEGG)
R11052
Substrate
8'-apo-beta-carotenal [CPD:C19728];
O2 [CPD:C00007]
Product
13-apo-beta-carotenone [CPD:C20696];
2,6-dimethyldeca-2,4,6,8-tetraenedial [CPD:C21078]
Comment
Isolated from the bacterium Novosphingobium aromaticivorans. It is less active with 4'-apo-beta-carotenal and gamma-carotene.
History
EC 1.13.11.82 created 2015
Orthology
K21822  8'-apo-carotenoid 13,14-cleaving dioxygenase
Genes
ACD: AOLE_09020
AWU: BEN71_01460
ACHI: CDG60_05985
RGU: A4W93_24915
MRD: Mrad2831_6035
MOR: MOC_3704
MAQU: Maq22A_2p40185
MPHY: MCBMB27_02697
METX: A3862_15320
MMES: MMSR116_02675
CSE: Cseg_2406
NAR: Saro_3580
SAL: Sala_1698
SPHP: LH20_08885
SMAZ: LH19_16255
SPHU: SPPYR_2343
 » show all
Reference
1  [PMID:22711425]
  Authors
Kim YS, Seo ES, Oh DK
  Title
Characterization of an apo-carotenoid 13,14-dioxygenase from Novosphingobium aromaticivorans that converts beta-apo-8'-carotenal to beta-apo-13-carotenone.
  Journal
Biotechnol Lett 34:1851-6 (2012)
DOI:10.1007/s10529-012-0969-5
  Sequence
[nar:Saro_3580]
Other DBs
ExplorEnz - The Enzyme Database: 1.13.11.82
IUBMB Enzyme Nomenclature: 1.13.11.82
ExPASy - ENZYME nomenclature database: 1.13.11.82
BRENDA, the Enzyme Database: 1.13.11.82

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