KEGG   ENZYME: 1.13.12.1
Entry
EC 1.13.12.1                Enzyme                                 
Name
arginine 2-monooxygenase;
arginine monooxygenase;
arginine decarboxylase (incorrect);
arginine oxygenase (decarboxylating);
arginine decarboxy-oxidase
Class
Oxidoreductases;
Acting on single donors with incorporation of molecular oxygen (oxygenases);
With incorporation of one atom of oxygen (internal monooxygenases or internal mixed-function oxidases)
Sysname
L-arginine:oxygen 2-oxidoreductase (decarboxylating)
Reaction(IUBMB)
L-arginine + O2 = 4-guanidinobutanamide + CO2 + H2O [RN:R00559]
Reaction(KEGG)
R00559
Substrate
L-arginine [CPD:C00062];
O2 [CPD:C00007]
Product
4-guanidinobutanamide [CPD:C03078];
CO2 [CPD:C00011];
H2O [CPD:C00001]
Comment
A flavoprotein. Also acts on canavanine and homoarginine.
History
EC 1.13.12.1 created 1972
Pathway
ec00330  Arginine and proline metabolism
ec01100  Metabolic pathways
Reference
1  [PMID:4295160]
  Authors
Olomucki A, Pho DB, Lebar R, Delcambe L, Thoai NV.
  Title
[Arginine oxygenase (decarboxylating). V. Purification and flavin nature]
  Journal
Biochim Biophys Acta 151:353-66 (1968)
DOI:10.1016/0005-2744(68)90102-2
Reference
2  [PMID:14479405]
  Authors
NGUYEN-VAN-THOAI, OLOMUCKI A
  Title
[Arginine decarboxyoxidase. I. Characteristics and nature of the enzyme].
  Journal
Biochim Biophys Acta 59:533-44 (1962)
DOI:10.1016/0006-3002(62)90631-5
Reference
3  [PMID:14479406]
  Authors
NGUYEN-VAN-THOAI, OLOMUCKI A
  Title
[Arginine decarboxyoxidase. II. Oxidation of canavanine and homoarginine to beta-guanidoxy-propionamide and delta-guanidovaleramide].
  Journal
Biochim Biophys Acta 59:545-52 (1962)
DOI:10.1016/0006-3002(62)90632-7
Other DBs
ExplorEnz - The Enzyme Database: 1.13.12.1
IUBMB Enzyme Nomenclature: 1.13.12.1
ExPASy - ENZYME nomenclature database: 1.13.12.1
BRENDA, the Enzyme Database: 1.13.12.1
CAS: 9027-36-5

  All links  
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG REACTION (1)   
   KEGG RCLASS (1)   
Protein sequence (1)   
   UniProt (1)   
DNA sequence (2)   
   GenBank (1)   
   EMBL (1)   
All databases (14)   

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